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2.1
Anetoderma Type Schweninger-Buzzi
Schweninger-Buzzi Anetoderma

Presentation

In the present case, the prothrombotic state was yet asymptomatic but the presence of primary anetoderma has directly led to the search for antiphospholipid antibodies. [kosmetischemedizin-online.de]

The present review summarizes the literature, from the early descriptions pointing toward an immunologic basis of PA and up to the present recognition that PA is a cutaneous sign for autoimmune disorders, in general, and the presence of antiphospholipid [ncbi.nlm.nih.gov]

The day before the admission he presented purpura of the skin of the right ankle, of the bottom and of the knees. [ispub.com]

Skin

  • Keratosis

    […] pilaris (Medical Encyclopedia) Lichen planus (Medical Encyclopedia) Milia (Medical Encyclopedia) Sebaceous cyst (Medical Encyclopedia) Seborrheic keratosis (Medical Encyclopedia) Skin lesion removal (Medical Encyclopedia) Skin lesion removal-aftercare [icdlist.com]

    September 01, 2011 Herpetic folliculitis in seborrheic keratosis of the head. September 01, 2011 Beneficial effects of neutrophil-targeted therapy for pyoderma gangrenosum associated with ulcerative colitis. [medscape.com]

    Some of this may be caused by actinic keratosis, which occurs due to overexposure to sun or with age and hormonal shifts. [en.wikipedia.org]

    Cutis 31:55–58 PubMed Google Scholar Dammerat K, Putkonen T (1958) Keratosis follicularis serpiginosa Lutz. [link.springer.com]

    Perifollicular atrophy also has been described in extreme forms of keratosis pilaris, in which large keratin plugs may produce a dilated patulous follicle. This condition usually found on the cheeks of young children. [bmcdermatol.biomedcentral.com]

  • Cutaneous Manifestation

    We recommend that PA be added to the list of the cutaneous manifestations of APS. [ncbi.nlm.nih.gov]

    Cutaneous manifestations of antiphospholipid antibody syndrome. Hematol Oncol Clin North Am. 2008 Feb. 22(1):67-77, vi. [Medline]. Kim JE, Sohn KM, Woo YJ, Jeong KH, Kim M, Lee JD, et al. [emedicine.medscape.com]

    Anetoderma, first described by Jadassohn in 1892, is a rare cutaneous disorder characterized by localized areas of elastolysis.[1] Histological examination of lesions demonstrates focal loss of elastic fibers in the superficial and mid-dermis, which manifests [jcadonline.com]

Workup

The specific diagnostic workup and treatments for corns may differ substantially from other forms of calluses. Prevention [ edit ] Corns and calluses are easier to prevent than to treat. [en.wikipedia.org]

Am J Dermatopathol 36:449–464 CrossRef PubMed Google Scholar Girardi M, Kay J, Elston DM et al (2011) Nephrogenic systemic fibrosis: clinicopathological definition and workup recommendations. [link.springer.com]

Treatment

Established lesions can be excised for definitive treatment, but this leaves permanent scars. [altmeyers.org]

We describe a striking case of primary anetoderma and review the classification, differential diagnosis, causes, and treatment. [ncbi.nlm.nih.gov]

Three recent studies have reported clinical and histopathological improvement using laser therapy as an alternative treatment modality.(4,5,6) TREATMENT: After establishing the diagnosis, the patient was sent for laboratory screening to evaluate for potential [aocd-grandrounds.org]

Prognosis

Mycosis fungoides: disease evolution and prognosis of 309 Dutch patients. Arch Dermatol 136: 504510. ‎ Seite 22 - M, et al. Transformation of mycosis fungoides: clinicopathological and prognostic features of 45 cases. [books.google.de]

This classification does not predict prognosis and is therefore no longer used. There have been many theories proposed to describe the mechanism of development of anetoderma, but at this time this remains unknown. [dermnetnz.org]

The two types of primary anetoderma can coexist in the same patient, and the prognosis and histopathology are identical in both. Thus this differentiation is of historical interest only. [dvkeywords.blogspot.com]

This classification is only of historical interest, because the two types of lesions can co-exist in the same patient; the prognosis and the histopathology are also the same. [dermaamin.com]

Etiology

Abstract Anetoderma is a rare disease of unknown etiology, today classified as a subtype of the circumscribed elastotic disorders. [onlinelibrary.wiley.com]

[…] that the biopsy demonstrates a loss of elastic fibers along with vascular inflammation, there are multiple etiologies that might be possible in this case. [vgrd.org]

The progressive positivization of autoimmunity of this patient seems to be triggered by HSP or to be linked to the etiology of the purpura. [ispub.com]

All of these studies returned as unremarkable, ruling against an autoimmune etiology. [aocd-grandrounds.org]

Anetoderma is a rare benign condition of diverse etiology whose characteristic is the diminution or absence of the dermal elastic fibers. Classified as primary and secondary, the latter associated with tumors, inflammatory, and infectious diseases. [pubfacts.com]

Epidemiology

Definition / general Benign disorder of focal loss of dermal elastic tissue, causing focal flaccid or saclike skin Either primary (idiopathic) arising in normal skin, or secondary arising at site of previous skin lesions Terminology Greek: Anetos means slack Epidemiology [pathologyoutlines.com]

▪ ANETODERMA History Epidemiology The lesions in anetoderma usually occur in young adults between the age of 15 and 30 years of age and more frequently in women than men. Anetoderma is rare, but the incidence is unknown. [dermaamin.com]

Pharmaco-epidemiological data indicate that 30% of anthrax vaccine recipients experience mild local reactions. With large numbers of military personnel being vaccinated, emergency physicians may encounter more vaccine-related adverse reactions.” [medscienceresearch.com]

These findings suggest that in addition to elastolytic overactivity, altered reassembly of elastic fibers may also play a significant role in the pathogenesis anetoderma. [4] Epidemiology Frequency The exact incidence of anetoderma is unknown, but secondary [emedicine.medscape.com]

Pathophysiology

Case Overview anetoderma Member Rated 0 Patient case no. 2362 Date added 14 June 2003 Patient details Age --Undetermined-- Localisation Upper limbs / Folds / axillae Primary Lesions Anetoderma Pathophysiology Symptoms Asymptomatic, Diagnosis anetoderma [dermquest.com]

[…] such as whole-exome sequencing will identify even more single-gene disorders and even allow us to classify them according to their patient-specific mutations. 3 Recently, studies in rare inherited skin disorders have also led to new insight into the pathophysiology [accessmedicine.mhmedical.com]

Moreover, the pathophysiology, as well as a temporary relationship between APA, SLE development and onset of anetoderma, have not been well established. [medicaljournals.se]

A familial form that manifests as primary anetoderma has also been described. [1] Pathophysiology The exact cause of anetoderma is unknown. [emedicine.medscape.com]

Specifically, impairments of the SC permeability barrier, antimicrobial barrier, and immunologic barrier contribute markedly to the fundamental pathophysiology of AD. [read.qxmd.com]

Prevention

Your skin Holds body fluids in, preventing dehydration Keeps harmful microbes out, preventing infections Helps you feel things like heat, cold, and pain Keeps your body temperature even Makes vitamin D when the sun shines on it Anything that irritates [icdlist.com]

Prevention [ edit ] Corns and calluses are easier to prevent than to treat. When it is usually not desirable to form a callus, minimizing rubbing and pressure will prevent callus formation. [en.wikipedia.org]

Colchicine has been shown to prevent the development of new primary anetoderma lesions. In secondary anetoderma, control of the causative dermatoses should theoretically prevent the development of new lesions (Kineston DP et al 2008). [altmeyers.org]

SHOWING 1-10 OF 76 REFERENCES Antiphospholipid syndrome associated recurrent pregnancy loss: treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone APLASA study update: primary thrombosis prevention in asymptomatic aPL( ) patients [semanticscholar.org]

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