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2.1
Angioma Serpiginosum

Presentation

To present a case of a young woman with linear distribution of angioma serpiginosum and review the common clinical characteristics and presentation of this condition. Case report with skin biopsies and dermoscopic findings. [ncbi.nlm.nih.gov]

We are presenting a case of this rare disease in an 11-year-old girl who presented with this condition on abdomen in zosteriform pattern which is rare presentation and is the first of its type. 05 Jan 2021Submitted to Clinical Case Reports 05 Jan 2021Submission [authorea.com]

CASE PRESENTATION: We describe the first Italian report of angioma serpiginosum with a congenital symmetrical presentation. The patient had a further extension of macules during puberty involving both of the soles. [moh-it.pure.elsevier.com]

Objective : To present a case of a young woman with linear distribution of angioma serpiginosum and review the common clinical characteristics and presentation of this condition. Methods : Case report with skin biopsies and dermoscopic findings. [pubfacts.com]

Case presentation: We describe the first Italian report of angioma serpiginosum with a congenital symmetrical presentation. The patient had a further extension of macules during puberty involving both of the soles. [pubmed.ncbi.nlm.nih.gov]

Entire Body System

  • Hunting

    Hunt SJ, Santa Cruz DJ. Acquired benign and “borderline” vascular lesions. Dermatol Clin 1992;10:97-115. 2. Happle R. Capillary malformations: A classification using specific names for specific skin disorders. [e-ijd.org]

    References Hunt SJ, Santa Cruz DJ (1992) Acquired benign and "borderline" vascular lesions. Dermatol Clin 10: 97-115. Chen W, Liu TJ, Yang YC, Happle R (2006) Angioma serpiginosum arranged in a systematized segmental pattern suggesting mosaicism. [omicsonline.org]

    Hunt SJ, Santa Cruz DJ. Acquired benign and "borderline" vascular lesions. Dermatol Clin. 1992;10:97–115. [PubMed] [Google Scholar] 5. Ohnishi T, Nagayama T, Morita T, Miyazaki T, Okada H, Ohara K, et al. [ncbi.nlm.nih.gov]

  • Collapse

    Open in viewer Go to Go to Show all references Request permissions Show all Collapse Expand Table Show all View all authors and affiliations CQ Library American political resourcesopens in new tab Data Planet A universe of dataopens in new tab Lean Library [journals.sagepub.com]

Skin

  • Brittle Hair

    The main features are congenital skin hypoplasia or atrophy following the lines of Blaschko, dysplastic nails, sparse or brittle hair, skin telangiectasias, limb anomalies, and multiple papillomas of the skin and mucous membranes.19 There are also reports [nature.com]

  • Darier's Sign

    However, Darier’s sign was negative. The rest of the cutaneous and systemic examination was unremarkable. Laboratory tests including blood counts and serum biochemistry were within the normal range. [termedia.pl]

    Darier's sign in mastocytosis. Blood 2014;123:1127. 9. Watkins CE, Bokor WB, Leicht S, Youngberg G, Krishnaswamy G. Telangiectasia macularis eruptiva perstans: More than skin deep. Dermatol Reports 2011;3:e12. 10. Marriott PJ, Munro DD, Ryan T. [indjvascsurg.org]

  • Hypopigmented Macule

    "Dyschromatoses" involve both hyperpigmented and hypopigmented macules. See also. [zqmjrolk.cf]

  • Lichenification

    Eczema, unlike AS, is a condition characterized by intense pruritus, xerosis, crusting, lichenification and poor circumscription [5]. Angiokeratomas may be distinguished from AS due to their rough, scaly textures [4]. [ospublishers.com]

Workup

Additionally, in the case of an erythematous lesion refractory to several months of corticosteroid therapy or multiple types of topical medications, it is beneficial to pursue further workup via skin biopsy or an earlier referral to a dermatologist. [ospublishers.com]

Treatment

Pulsed-dye laser treatment of angio- 5. ma serpiginosum. Clin Exp Dermatol. 2009;34(5):e186-8. 2. Crocco E, Abramavicus A, Russo C, Zaitz C, Nunes K. Treatment of port wine stain with pulsed light of the square pulse type. [surgicalcosmetic.org.br]

Treatment Options Treatment is usually unnecessary. It can be treated with pulsed dye laser. Optimal Therapeutic Approach for Angioma serpiginosum Treatment is usually unnecessary. Reassurance is key. [dermatologyadvisor.com]

In one patient, the angiomatous lesion improved but the patient developed hyperpigmentation at the treatment site and the treatment has been temporarily suspended. [ncbi.nlm.nih.gov]

Prognosis

Prognosis - Angioma serpiginosum- X-linked Not supplied. Treatment - Angioma serpiginosum- X-linked Not supplied. Resources - Angioma serpiginosum- X-linked [checkorphan.org]

The authors describe in-depth the clinical and morphologic aspects of each entity and detail their clinicopathologic correlation, differential diagnosis, prognosis, and therapy. [books.google.com]

Course and Prognosis After an initial period of growth, the lesions usually stop growing at puberty and remains stable during adulthood They may at times spontaneously resolve partially sometimes resulting in atrophy. [ncbi.nlm.nih.gov]

Etiology

Etiology The etiology is unknown. Pathophysiology Dilated capillaries in the dermal papillae without inflammation Systemic Implications and Complications AS is asymptomatic. It can become a cosmetic concern. [psychiatryadvisor.com]

The etiology is unknown. Some authors include angioma serpiginosum to the nevi, others to capillaritis. Localizes the process often on the skin of the feet. The lesions grow on the periphery due to the extension of knots-satellites. [medicalency.com]

Epidemiology

Summary Epidemiology The disease occurs almost exclusively in females. Etiology A mutation in the Xp11.3-Xq12 region has been identified in one of the reported families. [orpha.net]

PORCN gene mutations or deletions have been reported in angioma serpiginosum. [9] Angioma serpiginosum may represent type 1 mosaicism. [10] Etiology Angioma serpiginosum may be familial, with autosomal dominant inheritance and variable penetrance. [11] Epidemiology [emedicine.medscape.com]

The view that angioma serpiginosum represents a mild form of focal dermal hypoplasia (FDH), which can be associated with PORCN gene mutations, has also been opposed by later reports.[5] Epidemiology Females are almost exclusively affected than males with [ncbi.nlm.nih.gov]

Pathophysiology

Pathophysiology Dilated capillaries in the dermal papillae without inflammation Systemic Implications and Complications AS is asymptomatic. It can become a cosmetic concern. Treatment Options Treatment is usually unnecessary. [psychiatryadvisor.com]

Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any [books.google.de]

Prevention

Prevention - Angioma serpiginosum- X-linked Not supplied. Diagnosis - Angioma serpiginosum- X-linked Not supplied. Prognosis - Angioma serpiginosum- X-linked Not supplied. Treatment - Angioma serpiginosum- X-linked Not supplied. [checkorphan.org]

Angioma Serpiginosum may not be preventable, if it is an inherited condition. [dovemed.com]

The information presented here is not intended to diagnose, treat, cure or prevent any disease. Read disclaimer. [gulfdoctor.net]

Exclusion of purpura from the differential diagnosis is important to prevent unnecessary investigations. [ncbi.nlm.nih.gov]

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