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Angiostrongylus Costaricensis


Presentation

  • The present work demonstrated the usefulness of the egg antigen in the development of a specific diagnostic test for abdominal angiostrongylosis.[ncbi.nlm.nih.gov]
  • Extensive inflammatory lesions of terminal ileum and cecum, with perforations of the first, were present, and ileocecal resection was performed.[ncbi.nlm.nih.gov]
  • Abdominal pain which presents as a palpable mass on clinical examination Anorexia Diarrhoea VomitingIn the blood and tissue biopsy there is eosinophilia. Other methods of diagnosis from a biopsy are eggs and larvae in the blood vessels.[en.wikipedia.org]
  • All patients presented with abdominal pain associated with high blood eosinophilia (median: 7.24 G/L [min 4.25; max 52.28 G/L]).[ncbi.nlm.nih.gov]
  • Total cellular extracts from both genders showed similar 2-DE profiles, with 60% of all protein spots focused between pH 5-7 and presenting molecular masses from 20.1 to 66 kDa.[ncbi.nlm.nih.gov]
Anemia
  • Cerebrovascular disease in symptomatic and asymptomatic patients with sickle cell anemia: screening with duplex transcranial Doppler US — correlation with MR imaging and MR angiography. Radiology 1993; 189:457-466. ‎[books.google.es]
  • These two cases were characterized by weight loss, anemia, and a long hospital stay ( Table 1 ), consistent with the results observed in the three reported pediatric cases in Martinique and Guadeloupe in the 1980's [ 24, 26 ].[parasite-journal.org]
Weight Loss
  • These two cases were characterized by weight loss, anemia, and a long hospital stay ( Table 1 ), consistent with the results observed in the three reported pediatric cases in Martinique and Guadeloupe in the 1980's [ 24, 26 ].[parasite-journal.org]
Acute Abdomen
  • We report here a case of abdominal angiostrongyliasis in a 9-year-old girl, from Itatiba, State of Espirito Santo, Brazil, submitted to exploratory laparotomy for acute abdomen.[ncbi.nlm.nih.gov]
  • The clinical symptoms were those of "acute abdomen," with pain at the right iliac fossa, pain on palpation, a tumor-like mass, abdominal rigidity, and painful rectal examination. The picture was, nevertheless, mild to moderate.[ncbi.nlm.nih.gov]
Abdominal Rigidity
  • The clinical symptoms were those of "acute abdomen," with pain at the right iliac fossa, pain on palpation, a tumor-like mass, abdominal rigidity, and painful rectal examination. The picture was, nevertheless, mild to moderate.[ncbi.nlm.nih.gov]
Abdominal Tenderness
  • Case definition We defined a confirmed case as a patient with clinical symptoms and biological results consistent with HAA (fever, abdominal tenderness, and blood eosinophilia) and histopathological findings of HAA (identification of worms, eggs, or larvae[parasite-journal.org]
Colic
  • Imagery was performed two days following hospitalization and revealed a distended left colic flexure. Figure 2 Microscopical aspects of the ileal specimen and parasitic stools examination of case No. 1. A.[parasite-journal.org]
Testicular Pain
  • An 8-year-old boy was admitted to hospital with acute testicular pain. A diagnosis of torsion of the testicle was made, and an orchidectomy was performed.[ncbi.nlm.nih.gov]

Workup

Pneumoperitoneum
  • Pneumoperitoneum under the right hypochondria (white arrow). B. Focus on the pneumoperitoneum (white arrow). Figure 4 Case No. 2 microscopic aspects of the ileo-colic specimen stained with HES. A.[parasite-journal.org]
Wuchereria Bancrofti
  • The antigen was cross-reactive with 30 cases from 9 out of 10 different kinds of nematodiasis (gnathostomiasis, strongyloidiasis, ascariasis, hookworm infections, trichinosis, toxocariasis, trichuriasis, onchocercosis and Wuchereria bancrofti infections[ncbi.nlm.nih.gov]

Treatment

  • Through this test it was possible to demonstrate a sharp and early decline in IgG1 antibody in serum samples taken from patients with histopathological diagnosis of abdominal angiostrongyliasis at different time points after surgical treatment.[ncbi.nlm.nih.gov]
  • Moreover, our findings represent a first step in the search for candidate proteins for diagnostic assays and the treatment of this parasitic infection. Copyright 2011 Elsevier B.V. All rights reserved.[ncbi.nlm.nih.gov]
  • , treatment, prevention, prognosis, and additional useful information HERE .[dovemed.com]
  • The four patients in our case series were treated with an anthelmintic as standard treatment for cases of high eosinophilia before diagnostic confirmation.[parasite-journal.org]
  • Among various treatment options, corticosteroid is the only effective treatment.[eurekaselect.com]

Prognosis

  • […] infections from these parasites resolve spontaneously without treatment Please find comprehensive information on Angiostrongyliasis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis[dovemed.com]
  • […] headaches significantly. 5 Albendazole may induce an exacerbation of meningitis, possibly due to an inflammatory response following parasite death. 6 Therefore a combination of corticosteroids and albendazole or mebendazole has been proposed. 5,7 The prognosis[academic.oup.com]
  • The disease is generally mild and self-limiting, but some cases can be complicated by intestinal infarction, pseudo-tumor, acute appendicitis, or digestive perforation, requiring emergency laparotomy and surgical care with an unpredictable prognosis [[parasite-journal.org]

Etiology

  • Etiological diagnoses were established by the discovery of Angiostrongylus costaricensis parasite in ileal pathological specimens.[clinicaltrials.gov]
  • Eosinophilia of undetermined origin is often treated using empirical anthelmintic treatment (generally a combination of albendazole or flubendazole and ivermectin) to cover a broad range of parasitic disease etiologies known in Martinique, including ascariasis[parasite-journal.org]

Epidemiology

  • Environmental and epidemiological studies are needed to broaden our knowledge of the burden of this disease.[ncbi.nlm.nih.gov]
  • Angiostrongyliasis, Angiostrongylus cantonensis, cerebrospinal fluid, diagnosis, eosinophilic meningitis, snail, eosinophils, Gnathostoma spinigerum, Taenia solium, Baylisascaris procyonis, gnathostomiasis, baylisascariasis, Angiostrongylus costaricensis, EPIDEMIOLOGY[eurekaselect.com]
Sex distribution
Age distribution

Prevention

  • […] the infections from these parasites resolve spontaneously without treatment Please find comprehensive information on Angiostrongyliasis regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention[dovemed.com]
  • Bulletin de l’Académie Nationale de Médecine, 178, 625-631. [ 13 ] Zanini, G.M. and Graeff-Teixeira, C. (1995) Abdominal Angiostrongyliasis: Its Prevention by the Destruction of Infecting Larvae in Food Treated with Salt, Vinegar or Sodium Hypochlorite[scirp.org]
  • Indeed, detection of A. costaricensis eggs in feces has rarely been described, since their elimination is prevented by the inflammatory reaction in the intestinal wall.[parasite-journal.org]

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