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Anisakis


Presentation

  • In the present study we determined the levels of anti-Anisakis antibodies in the serum of healthy people, and their relationship with the B and T cell subsets.[ncbi.nlm.nih.gov]
  • Commonly, these efforts have been focused on the developing of cDNA libraries, where virtually all expressed mRNAs are present, by using immunoreactive patient serum or polyclonal antibodies.[ncbi.nlm.nih.gov]
  • BACKGROUND: Anisakissimplex is the main organism responsible for the zoonotic disease anisakiasis which follows the ingestion of live larvae present in raw or undercooked marine fish.[ncbi.nlm.nih.gov]
  • The authors present four cases of infection due to Anisakis in an area where people are prone to infectious diseases transmitted by raw fish, but in which the presence of this parasite has never been reported.[ncbi.nlm.nih.gov]
  • We present three patients with proven hypersensitivity to A. simplex together with rheumatologic complaints after ingestion of parasitized fishes.[ncbi.nlm.nih.gov]
Dyspepsia
  • Comments: This 61 year old restaurant owner was referred for upper endoscopy to evaluate typical longstanding dyspepsia and reflux type symptoms.[web.archive.org]
Regurgitation
Arthritis
  • A. simplex must be considered in the differential diagnosis of arthralgias/ arthritis especially if associated with urticaria.[ncbi.nlm.nih.gov]
  • New research work is finding that helminths secrete interesting molecules which may have beneficial effects for cardiovascular disease ( 170 ), bowel disease, arthritis ( 191 ), and even allergic diseases ( 246 ).[dx.doi.org]
Arthralgia
  • A. simplex must be considered in the differential diagnosis of arthralgias/ arthritis especially if associated with urticaria.[ncbi.nlm.nih.gov]
  • […] aspects of A. simplex pathogenesis, such as rheumatologic manifestations, carcinogenic effects, and autoimmunity, may be associated with immunomodulatory effects and still remain to be explained, and the link between A. simplex and rheumatologic symptoms (arthralgia[dx.doi.org]

Workup

Gastric Lesion
  • The present results show that in the cases included in the study, gastric and intestinal localisations had very similar frequencies, only slightly higher for gastric lesions.[parasite-journal.org]
Polyps
  • In the course of the last EGDS, a white color round worm on antrum and a small polyp on the fundus of the stomach were observed.[ncbi.nlm.nih.gov]
  • Since the symptoms of anisakiasis are not pathognomonic, gastric anisakidosis is often misdiagnosed as peptic ulcer, stomach tumour or stomach polyps, while intestinal anisakidosis is often misdiagnosed as appendicitis, ileus, or peritonitis [ 62, 103[parasite-journal.org]
HLA-B12
  • Class I HLA expressed by the patient was type HLA-B12. Other secondary causes of nephrotic syndrome were carefully ruled out. These data suggest, for the first time, the association between allergy to A. simplex and nephrotic syndrome.[ncbi.nlm.nih.gov]

Treatment

  • […] retained their allergenicity even after the larvae were killed by both heat treatments.[ncbi.nlm.nih.gov]
  • There are cases of successful medical treatment and other cases of endoscopic treatment avoiding surgical procedure.[ncbi.nlm.nih.gov]
  • This can be suspected in cases of gastritis or non filiated enteritis with a torpid evolution following the conventional treatment and especially if the onset of the symptoms is related with the intake of fish.[ncbi.nlm.nih.gov]
  • Since conservative medical treatment for acute anisakiasis relies on endoscopic removal of the nematode from the gastrointestinal wall if performed within 12h from the ingestion of contaminated fish, it should be compulsory to consider this parasitosis[ncbi.nlm.nih.gov]
  • The stability to pepsin digestion and heat treatment of rAni s 11-like protein was also analysed by IgE immunoblotting.[ncbi.nlm.nih.gov]

Etiology

  • In recent years, Anisakis simplex has been shown to be an important etiologic agent responsible for food allergy and for gastrointestinal anisakiasis.[ncbi.nlm.nih.gov]
  • The molecular identification of the etiological agent at the species level allows to identify what Anisakidae species play a zoonotic role and which are the fish host species.[ncbi.nlm.nih.gov]
  • Etiological study of nephrotic syndrome and urticaria/angioedema, cutaneous test, serum total and specific IgE determination, IgE-immunoblotting, and HLA typing were performed for diagnostic evaluation.[ncbi.nlm.nih.gov]
  • After genomic DNA isolation of the nematode from the histological section, and amplification at the mitochondrial cytochrome oxidase 2 locus, etiological agent has been identified as Anisakis pegreffii.[ncbi.nlm.nih.gov]
  • BACKGROUND: The etiology of Crohn's disease (CD) is still unknown although new theories are based on defects in innate immunity. We have previously shown a decrease in γδ T cells in CD patients.[ncbi.nlm.nih.gov]

Epidemiology

  • Female Fish Diseases/epidemiology Fish Diseases/parasitology* Humans Male Morocco/epidemiology Muscles/parasitology Perciformes* Polymerase Chain Reaction Polymorphism, Restriction Fragment Length Prevalence RNA, Ribosomal, 5.8S/genetics Seasons Substances[ncbi.nlm.nih.gov]
  • Used methodology suggests that screening of archival suspicious sections is feasible in order to study epidemiology of this zoonotic disease poorly recognised in Croatia.[ncbi.nlm.nih.gov]
  • In spite of the animal and human health significance of these parasites, there are still gaps in our understanding of the systematics, biology, epidemiology and ecology of anisakids.[ncbi.nlm.nih.gov]
  • This finding is of great epidemiological relevance for wildlife managers and consumers, considering the zoonotic and gastroallergic threats posed of these parasites.[ncbi.nlm.nih.gov]
  • Geographical distribution and epidemiology, p. 31-36. In H. Ishikura and M. Namiki (ed.), Gastric anisakiasis in Japan. Epidemiology, diagnosis, treatment. Springer-Verlag, Tokyo, Japan. 21. Asato, R., M. Wakuda, and T. Sueyoshi. 1991.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Prevention

  • Anisakiasis and gastroallergic reactions can be prevented by consuming only fish that has been frozen to -20 C to the core for at least 24 hours before preparation.[ncbi.nlm.nih.gov]
  • The study suggested the importance to adopt specific prevention strategies against exposure to AS in the occupational setting.[ncbi.nlm.nih.gov]
  • Preventive measures for anisakiosis focus on post-harvest handling.[ncbi.nlm.nih.gov]
  • Although preliminary, our data may suggest that parenteral corticosteroids could be a reasonable, inexpensive, and safe alternative in these patients to prevent intestinal resection.[ncbi.nlm.nih.gov]
  • Raising consumer and producer awareness about the existence of anisakid worms in fish is a critical and effective prevention strategy. Anisakiasis can be easily prevented by adequate cooking at temperatures greater than 60 C or freezing.[en.wikipedia.org]

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