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Anonychia with Flexural Pigmentation


Presentation

  • Variably present Usually present, marked back Histopathology Hyperkeratosis Parakeratosis Infiltrate Lymphocytes Histiocytes Giant cells Dyskeratotic,Variable and focal Mostly present Focal in one to three papillary bodies Variable Variable, almost always[brainrush.com]
  • We present six unusual cases of ulcerated CCLE and LP. Case Report Clinical details of all the cases are summarized in [Table 1].[ijdpdd.com]
  • Some patients may also present dental abnormalities. As its name suggests, EBS with pyloric atresia presents with pyloric atresia at birth and, usually, blistering is widespread.[slideplayer.com]
  • Allen is a 66-year-old man who presents to your clinic for follow-up for his COPD.[quizlet.com]
  • Chronic application of topical corticosteroids can mask the clinical presentation (tinea incognito).[criticalcaremcqs.com]
Gangrene
  • Pseudomonas infection Peritonitis Anaerobic infection Clostridium gas gangrene Mrs. Nieland brings her toddler in for a routine office visit. She tells you that she has a new babysitter.[quizlet.com]

Treatment

  • Stay at the forefront of your field with updated treatment methods throughout, as well as an increased focus on patients with skin of color.[books.google.com]
  • Treatment Options Table II. Treatment Ladder for Cutaneous Lichen Planus Table II.[clinicaladvisor.com]
  • Available from: Introduction Cutaneous ulcers are challenging with respect to diagnosis and treatment because of heterogeneous etiopathogenesis.[ijdpdd.com]
  • […] of Pigmentary Disorders 59 Topical Treatment of Pigmentary Disorders 60 Chemophototherapy of Pigmentary Disorders 61 UVB Therapy for Pigmentary Disorders 62 Sunscreens and Cosmetics 63 Surgical Treatments of Pigmentary Disorders 64 Laser Treatment of[homepage.vghtpe.gov.tw]

Prognosis

  • In most patients, even with correction of pyloric atresia, prognosis is unfavorable, given the extent of systemic involvement.[slideplayer.com]
  • Slow tapering of steroid over months is required Rosacea Fulminans (Pyoderma Faciale) • Occurs almost exclusively in post-adolescent women; lots of flushing and blushing • Large coalescent nodules and confluent draining sinus occupy most of the face • Prognosis[slideshare.net]
  • A Chinese newborn with reticulate pigmented anomaly of the flexures was recently described. [21] Prognosis Dowling-Degos disease (reticulate pigmented anomaly) is slowly progressive but not life threatening.[emedicine.medscape.com]
  • […] viscera, and lymph nodes or any organ Alopecia Areata sudden, rapid, patchy hair loss usually from scalp or face patho: unknown cause; genetic-environmental interaction may trigger any hair-bearing surface may be affected regrowth begins in 1-3 months; prognosis[quizlet.com]

Etiology

  • Distinctive microscopic features Shares microscopic inflammatory pattern with several dermatoses Lichenoid reaction is just a histologic description of a pathologic characteristic resembling lichen planus back Four Ps Purple Polygonal Pruritic Papule back Etiology[brainrush.com]
  • Etiology Pathophysiology The etiology of LP is unknown. It is believed to be an autoimmune disorder involving the activation of T-lymphocytes against basal keratinocytes. Both CD4- and CD8-positive lymphocytes have been implicated.[clinicaladvisor.com]
  • Etiology See Pathophysiology. Dowling-Degos disease (reticulate pigmented anomaly) may coexist with hidradenitis suppurativa.[emedicine.medscape.com]
  • Pityriasis Rosea self-limiting inflammation of unknown cause Patho: possible infectious etiology not contagious Subjective: sudden onset w/occurence of primary (herald) oval or round plaque herald lesion often missed eruption occurs 1-3 weeks later and[quizlet.com]
  • The clinical differential diagnoses for cutaneous ulceration are wide and particularly in the Indian setting, infectious etiologies'(mycobacterial and fungal) are prime considerations.[ijdpdd.com]

Epidemiology

  • An epidemiological study of 2071 patients and a review of the literature. Arch Dermatol. vol. 127. 1991. pp. 1684-8. (Thorough study of Swedish population demonstrating no increased risk of cutaneous or internal malignancy with LP.[clinicaladvisor.com]
  • Epidemiology Frequency Dowling-Degos disease (reticulate pigmented anomaly) is a rare condition worldwide. Sex Dowling-Degos disease (reticulate pigmented anomaly) affects both sexes.[emedicine.medscape.com]
  • […] symmetric synovitis, tenosynovitis and tendon friction rubs often present; nail fold capillary dilatation and destruction  • arly onset of internal organ involvement; anti-topoisomerase 1 antibodies (SCL- E 70) in 30%; worse survival rate (15% at 12 years)Epidemiology[slideshare.net]
Sex distribution
Age distribution

Pathophysiology

  • (Archives of Dermatology) 'This book is the first comprehensive treatise on pigmentation that combines its physiology in animals with its pathophysiology and clinical aspects in humans.'[bookdepository.com]
  • Etiology See Pathophysiology. Dowling-Degos disease (reticulate pigmented anomaly) may coexist with hidradenitis suppurativa.[emedicine.medscape.com]
  • Disorders 22 Growth Factor Receptors and Signal Transduction Regulating the Proliferation and Differentiation of Melanocytes 23 Aging and Senescence of Melanocytes 24 The Genetics of Melanoma 25 The Transformed Phenotype of Melanocytes Part II: The Pathophysiology[homepage.vghtpe.gov.tw]
  • Part II: The Pathophysiology of Pigmentary Disorders. Section 3: An Overview of Human Skin Color and itsDisorders. 26 A More Precise Lexicon for Pigmentation, PigmentaryDisorders, and "Chromatic" Abnormalities ( James J.[amazon.it]
  • Etiology Pathophysiology The etiology of LP is unknown. It is believed to be an autoimmune disorder involving the activation of T-lymphocytes against basal keratinocytes. Both CD4- and CD8-positive lymphocytes have been implicated.[clinicaladvisor.com]

Prevention

  • - 0% Emergent - ED Care Needed - Preventable/Avoidable - 0% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary diagnosis[medicbind.com]
  • The skin should be left in place, functioning as a biological dressing and preventing bacterial colonization. Firm and easily torn crusts require debridement to prevent maintenance of the inflammatory process.[slideplayer.com]
  • While verification may prevent the occasional error, its purpose is to verify process and objectivity as opposed to only check results. It is also an excellent vehicle for training.”[fprints.nwlean.net]
  • "Children have very little skin mass, which prevents development of acne." "At puberty, adolescents begin to secrete more oil from sebaceous glands." While examining the skin of an 87-year-old woman, the nurse observes significant tenting.[quizlet.com]
  • […] of atopic dermatitis has been studied • Lactobacillus GG cultures were given to pregnant women with a history of atopy to assess the effect of potentially beneficial gut flora on the prevention of atopic disease in their children • Frequency of atopic[slideshare.net]

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