Presentation
Variably present Usually present, marked back Histopathology Hyperkeratosis Parakeratosis Infiltrate Lymphocytes Histiocytes Giant cells Dyskeratotic,Variable and focal Mostly present Focal in one to three papillary bodies Variable Variable, almost always [brainrush.com]
We present six unusual cases of ulcerated CCLE and LP. Case Report Clinical details of all the cases are summarized in [Table 1]. [ijdpdd.com]
Some patients may also present dental abnormalities. As its name suggests, EBS with pyloric atresia presents with pyloric atresia at birth and, usually, blistering is widespread. [slideplayer.com]
Allen is a 66-year-old man who presents to your clinic for follow-up for his COPD. [quizlet.com]
Chronic application of topical corticosteroids can mask the clinical presentation (tinea incognito). [criticalcaremcqs.com]
Skin
- Keratosis
[…] of the Palms and Soles Darier -White Disease ( Keratosis Follicularis;124200) Nevus Depigmentosus Tuberous Sclerosis Complex 33 Genetic Hypomelanoses : Disorders Characterized by Hypopigmentation of Hair Bird-Headed Dwarfism ( Seckel Syndrome) Down Syndrome [homepage.vghtpe.gov.tw]
Some skin and oral keratosis improved, but no palmo-plantar or nail improvement was noted. [sites.google.com]
L82.1 Other seborrheic keratosis L83 Acanthosis nigricans L84 Corns and callosities L85.0 Acquired ichthyosis L85.1 Acquired keratosis [keratoderma] palmaris et plantaris L85.2 Keratosis punctata (palmaris et plantaris) L85.3 Xerosis cutis L85.8 Other [icd10data.com]
Hypomelanosis with Punctate Keratosis of the Palms and Soles( Jean L. Bolognia ). Darier White Disease (Keratosis Follicularis;124200)( Jean L. Bolognia ). Nevus Depigmentosus ( Stella D. Calobrisi ). Tuberous Sclerosis Complex ( Pranav B. [amazon.it]
It is characterized by pigmented filiform epidermal papules closely resembling an adenoid seborrheic keratosis, but similar proliferations also develop around the variably dilated pilosebaceous follicles. [emedicine.medscape.com]
- Piebaldism
" Abnormalities 27 The Normal Color of Human Skin 28 Mechanisms that Cause Abnormal Skin Color Section 4: Disorders of Hypopigmentation, Depigmentation and Hypochromia 29 Genetic Hypomelanoses : Disorders Characterized by Congenital White Spotting - Piebaldism [homepage.vghtpe.gov.tw]
Section 4: Disorders of Hypopigmentation, Depigmentation andHypochromia. 29 Genetic Hypomelanoses: Disorders Characterized by CongenitalWhite Spotting Piebaldism, Waardenburg Syndrome, and RelatedGenetic Disorders of Melanocyte Development Clinical Aspects [amazon.it]
Section 4: Disorders of Hypopigmentation, Depigmentation and Hypochromia. 29 Genetic Hypomelanoses: Disorders Characterized by Congenital White Spotting-Piebaldism, Waardenburg Syndrome, and Related Genetic Disorders of Melanocyte Development-Clinical [bookdepository.com]
Lichen planus pilaris Piebaldism refers to KARNATAKA – PGMEE – 2006. a. Androgenetic alopecia b. Erythema nodosum leprosum c. Association of vitiligo with white forelock d. None of the above (Ref. [criticalcaremcqs.com]
- Skin Disease
The nails (see Chap. 72) can provide evidence of latent skin disease (psoriasis, lichen planus, alopecia areata, congenital ectodermal defect), as well as suggest the presence of renal or liver disease. [criticalcaremcqs.com]
Petechiae, purpura, waxy skin colored papules, alopecia, car- pal tunnel syndrome, neuropathy, arthropathSecondary AA Result of chronic disease: TB, leprosy, Hodgkin’s, RA, Reiter’s, syphilis No Skin involement Amyloid in the adrenals, liver, spleen, [slideshare.net]
Lyme Disease tick-borne disease that can lead to multi systemic infection patho: spirochete infection caused by Borrella burgdorferi. most common tick-borne disease in US spirochete is deposited by tick into skin rather than through blood stream. 3 phases [quizlet.com]
- Localized Scleroderma
[…] syndrome Autosomal dominant polycystic kidney disease Chronic nonbacterial osteomyelitis/Chronic recurrent multifocal osteomyelitis Dermatomyositis Familial dysfibrinogenemia Hemophilia Hemophilia A Hemophilia B Immunoglobulin A vasculitis Kawasaki disease Localized [se-atlas.de]
Chronic disease of unknown etiology affecting the microvasculature and loose connective tissue.Classification Localized Scleroderma • Morphea → most common type • Generalized morphea → morphea, symmetric and bilateral lesions; but absence of Raynaud’ [slideshare.net]
scleroderma [morphea] L94.1 Linear scleroderma L94.2 Calcinosis cutis L94.3 Sclerodactyly L94.4 Gottron's papules L94.8 Other specified localized connective tissue disorders L94.9 Localized connective tissue disorder, unspecified L95.0 Livedoid vasculitis [icd10data.com]
- Acne Vulgaris
White, MDC o n t e n t s4.1 Acne Vulgaris. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. 764.2 Rosacea. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. ... 794.3 Psoriasis. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. .. 814.4 Psoriatic [slideshare.net]
vulgaris L70.1 Acne conglobata L70.2 Acne varioliformis L70.3 Acne tropica L70.4 Infantile acne L70.5 Acné excoriée L70.8 Other acne L70.9 Acne, unspecified L71.0 Perioral dermatitis L71.1 Rhinophyma L71.8 Other rosacea L71.9 Rosacea, unspecified L72.0 [icd10data.com]
Acne vulgaris Cherry angioma Miliaria Trichotillomania The examiner notes hyperkeratosis on a patient's palms and soles. [quizlet.com]
Treatment
Treatment Options Table II. Treatment Ladder for Cutaneous Lichen Planus Table II. [clinicaladvisor.com]
This fully revised and updated edition of GENETIC SKIN DISORDERS reflects the most current understanding of the diagnosis, treatment, genetic basis, and differential diagnoses of inherited skin disorders. [books.google.com]
2016/3/1/7/184006 Introduction Cutaneous ulcers are challenging with respect to diagnosis and treatment because of heterogeneous etiopathogenesis. [ijdpdd.com]
[…] of Pigmentary Disorders 59 Topical Treatment of Pigmentary Disorders 60 Chemophototherapy of Pigmentary Disorders 61 UVB Therapy for Pigmentary Disorders 62 Sunscreens and Cosmetics 63 Surgical Treatments of Pigmentary Disorders 64 Laser Treatment of [homepage.vghtpe.gov.tw]
Prognosis
In most patients, even with correction of pyloric atresia, prognosis is unfavorable, given the extent of systemic involvement. [slideplayer.com]
Slow tapering of steroid over months is required Rosacea Fulminans (Pyoderma Faciale) • Occurs almost exclusively in post-adolescent women; lots of flushing and blushing • Large coalescent nodules and confluent draining sinus occupy most of the face • Prognosis [slideshare.net]
A Chinese newborn with reticulate pigmented anomaly of the flexures was recently described. [21] Prognosis Dowling-Degos disease (reticulate pigmented anomaly) is slowly progressive but not life threatening. [emedicine.medscape.com]
[…] viscera, and lymph nodes or any organ Alopecia Areata sudden, rapid, patchy hair loss usually from scalp or face patho: unknown cause; genetic-environmental interaction may trigger any hair-bearing surface may be affected regrowth begins in 1-3 months; prognosis [quizlet.com]
Etiology
Distinctive microscopic features Shares microscopic inflammatory pattern with several dermatoses Lichenoid reaction is just a histologic description of a pathologic characteristic resembling lichen planus back Four Ps Purple Polygonal Pruritic Papule back Etiology [brainrush.com]
Etiology Pathophysiology The etiology of LP is unknown. It is believed to be an autoimmune disorder involving the activation of T-lymphocytes against basal keratinocytes. Both CD4- and CD8-positive lymphocytes have been implicated. [clinicaladvisor.com]
Etiology See Pathophysiology. Dowling-Degos disease (reticulate pigmented anomaly) may coexist with hidradenitis suppurativa. [emedicine.medscape.com]
Pityriasis Rosea self-limiting inflammation of unknown cause Patho: possible infectious etiology not contagious Subjective: sudden onset w/occurence of primary (herald) oval or round plaque herald lesion often missed eruption occurs 1-3 weeks later and [quizlet.com]
The clinical differential diagnoses for cutaneous ulceration are wide and particularly in the Indian setting, infectious etiologies'(mycobacterial and fungal) are prime considerations. [ijdpdd.com]
Epidemiology
An epidemiological study of 2071 patients and a review of the literature. Arch Dermatol. vol. 127. 1991. pp. 1684-8. (Thorough study of Swedish population demonstrating no increased risk of cutaneous or internal malignancy with LP. [clinicaladvisor.com]
Epidemiology Frequency Dowling-Degos disease (reticulate pigmented anomaly) is a rare condition worldwide. Sex Dowling-Degos disease (reticulate pigmented anomaly) affects both sexes. [emedicine.medscape.com]
[…] symmetric synovitis, tenosynovitis and tendon friction rubs often present; nail fold capillary dilatation and destruction • arly onset of internal organ involvement; anti-topoisomerase 1 antibodies (SCL- E 70) in 30%; worse survival rate (15% at 12 years)Epidemiology [slideshare.net]
Pathophysiology
(Archives of Dermatology) 'This book is the first comprehensive treatise on pigmentation that combines its physiology in animals with its pathophysiology and clinical aspects in humans.' [bookdepository.com]
Etiology See Pathophysiology. Dowling-Degos disease (reticulate pigmented anomaly) may coexist with hidradenitis suppurativa. [emedicine.medscape.com]
Disorders 22 Growth Factor Receptors and Signal Transduction Regulating the Proliferation and Differentiation of Melanocytes 23 Aging and Senescence of Melanocytes 24 The Genetics of Melanoma 25 The Transformed Phenotype of Melanocytes Part II: The Pathophysiology [homepage.vghtpe.gov.tw]
Part II: The Pathophysiology of Pigmentary Disorders. Section 3: An Overview of Human Skin Color and itsDisorders. 26 A More Precise Lexicon for Pigmentation, PigmentaryDisorders, and "Chromatic" Abnormalities ( James J. [amazon.it]
Etiology Pathophysiology The etiology of LP is unknown. It is believed to be an autoimmune disorder involving the activation of T-lymphocytes against basal keratinocytes. Both CD4- and CD8-positive lymphocytes have been implicated. [clinicaladvisor.com]
Prevention
0% Emergent - ED Care Needed - Preventable/Avoidable - 0% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary diagnosis [medicbind.com]
The skin should be left in place, functioning as a biological dressing and preventing bacterial colonization. Firm and easily torn crusts require debridement to prevent maintenance of the inflammatory process. [slideplayer.com]
While verification may prevent the occasional error, its purpose is to verify process and objectivity as opposed to only check results. It is also an excellent vehicle for training.” [fprints.nwlean.net]
"Children have very little skin mass, which prevents development of acne." "At puberty, adolescents begin to secrete more oil from sebaceous glands." While examining the skin of an 87-year-old woman, the nurse observes significant tenting. [quizlet.com]
[…] of atopic dermatitis has been studied • Lactobacillus GG cultures were given to pregnant women with a history of atopy to assess the effect of potentially beneficial gut flora on the prevention of atopic disease in their children • Frequency of atopic [slideshare.net]