Abstract The anorectic patient presents a dilemma to the health care provider. As the patient refuses oral intake, quality of life diminishes, and health care costs increase. [ncbi.nlm.nih.gov]

• Weight Loss

  An anorectic or anorexic is a drug which reduces appetite, resulting in lower food consumption, leading to weight loss. [1] By contrast, an appetite stimulant is referred to as orexigenic. [en.wikipedia.org]

  BACKGROUND: Phentermine--fenfluramine and dexfenfluramine use for weight loss has been previously associated with increased prevalence of valvular heart disease. [ncbi.nlm.nih.gov]

  This appetite suppressant should only be prescribed for short term weight loss. The brand name for Mazindol is Sanorex and taken only as prescribed. [addictionsearch.com]

  Benzedrine - Weight Loss Support, Positive Moods & Energy Enhancer - Ingredients/Dose Benzedrine was previously marketed as the best weight loss pharmaceutical ever. [smartbodyz.com]

• Loss of Appetite

  Marked by loss of appetite. Suppressing or causing loss of appetite. Of or affected with anorexia nervosa. n. One who is affected with anorexia nervosa. An anorectic drug. [yourdictionary.com]

  Marked by loss of appetite. 2. Suppressing or causing loss of appetite. 3. Of or affected with anorexia nervosa. n. 1. One who is affected with anorexia nervosa. 2. [medical-dictionary.thefreedictionary.com]

  […] from anorexia nervosa; anorexic. anorectic (Adjective) Causing a loss of appetite. [definitions.net]

  Marked by loss of appetite. 2. Suppressing or causing loss of appetite. 3. Of or affected with anorexia nervosa. n. 1. An agent that causes loss of appetite. 2. One affected with anorexia nervosa. [whyeat.net]

  Wiktionary anorectic a. 1 Characterised by a lack of appetite, especially as suffering from anorexia nervosa; anorexic. 2 Causing a loss of appetite. n. 1 A person suffering from anorexia nervosa; an anorexic. 2 A drug or dietary supplement that reduces [findwords.info]

• Constipation

  Dizziness, dry mouth, difficulty sleeping, irritability, nausea, vomiting, diarrhea, or constipation may occur. [drugfree.org]

  The most frequent adverse effects of sibutramine are insomnia, constipation, mouth dryness, headache, tachycardia, palpitations, hypertension. [pharmacorama.com]

• Failure to Thrive

  These treatments are reproducible in a variety of clinical care settings and stimulate oral intake in the failure-to-thrive patient. [ncbi.nlm.nih.gov]

• Hypertension

  Their use has been associated with epidemics of pulmonary hypertension and the development of valvular heart disease, hypertension, stroke and digital or mesenteric ischemia. [ncbi.nlm.nih.gov]

  Many amphetamines produce side effects, including addiction, tachycardia and hypertension, [4] making prolonged unsupervised use dangerous. [en.wikipedia.org]

  The most frequent adverse effects of sibutramine are insomnia, constipation, mouth dryness, headache, tachycardia, palpitations, hypertension. [pharmacorama.com]

• Tachycardia

  The most frequent adverse effects of sibutramine are insomnia, constipation, mouth dryness, headache, tachycardia, palpitations, hypertension. [pharmacorama.com]

  Many amphetamines produce side effects, including addiction, tachycardia and hypertension, [4] making prolonged unsupervised use dangerous. [en.wikipedia.org]

  Adverse reactions: pulmonary hypertension, addiction, abstinence syndrome, psychotic reactions or psychosis, depression, nervousness, agitation, sleep disorders, Vertigo, tachycardia, hypertension, pericardial pain; isolated-cardiovascular or cerebral-vascular [diethics.com]

• Euphoria

  Dexamphetamine, phenmetrazine and benzphetamine all tend to cause euphoria and the risk of addiction is therefore considerable. Euphoria occasionally occurs with diethylpropion, phentermine and chlorphentermine, but to a much lesser extent. [ncbi.nlm.nih.gov]

  Previous Next CNS stimulants induce wakefulness, alertness, decreased sense of fatigue, euphoria without improving depressive mood. [pharmacorama.com]

  Medications that affect catecholamine levels (such as phentermine, dietylpropion, and mazindol) may cause symptoms of sleeplessness, nervousness, and euphoria. [encyclopedia.com]

• Secondary Amenorrhea

  Abstract In sixteen adolescent anorectic inpatients with secondary amenorrhea pelvic ultrasound examination of the ovaries was performed at lowest weight and after weight recovery. [ncbi.nlm.nih.gov]

• Irritability

  Dizziness, dry mouth, difficulty sleeping, irritability, nausea, vomiting, diarrhea, or constipation may occur. [drugfree.org]

  All the drugs, with the exception of fenfluramine, have a stimulant effect on the central nervous system in some individuals, resulting in restlessness and nervousness, irritability and insomnia. [ncbi.nlm.nih.gov]

  Its principal adverse effects are: irritability, insomnia, decrease of appetite, appearance of stereotyped movements and, exceptionally, delusion and hallucinations. [pharmacorama.com]

• Agitation

  Unlikely but serious side effects include fast/irregular/pounding heartbeat, mental/mood changes (agitation, uncontrolled anger, hallucinations, nervousness), uncontrolled muscle movements, and change in sexual ability/interest. [drugfree.org]

  Adverse reactions: pulmonary hypertension, addiction, abstinence syndrome, psychotic reactions or psychosis, depression, nervousness, agitation, sleep disorders, Vertigo, tachycardia, hypertension, pericardial pain; isolated-cardiovascular or cerebral-vascular [diethics.com]

  Intravenous agitated saline was infused to optimize the evaluation of systolic PAP. [doi.org]

• Insomnia

  The most frequent adverse effects of sibutramine are insomnia, constipation, mouth dryness, headache, tachycardia, palpitations, hypertension. [pharmacorama.com]

  All the drugs, with the exception of fenfluramine, have a stimulant effect on the central nervous system in some individuals, resulting in restlessness and nervousness, irritability and insomnia. [ncbi.nlm.nih.gov]

  It was mentioned that sympathomimetric drugs, including phendimetrazine have potential for adverse effects similar to amphetamine, such as insomnia. Therefore, phemdimetrazine was used for short-term treatment (less than 12 weeks) 21. [scialert.net]

• Hyperactivity

  […] patients, including factor I (eating behavior meeting the criteria of anorexia; concern with weight, foods, and denial), factor II (bulimia; including bingeing, disposing, furtive eating and purging, and talk about thinness and dieting), and factor III (hyperactivity [ncbi.nlm.nih.gov]

  […] necessary before prescription of a treatment by sibutramine Sibutramine MERIDIA* Capsules Other stimulants Methylphenidate inhibits dopamine and noradrenaline reuptake and is used clinically in a paradoxical therapeutic indication, the management of hyperactivity [pharmacorama.com]

Binge eating status was also assessed in pre-treatment. [ncbi.nlm.nih.gov]

Effects of a combination therapy of anticoagulant and vasodilator on the long-term prognosis of primary pulmonary hypertension. Jpn Circ J 1993;57:63–9. Kawut SM, Horn EM, Berekashvili KK, et al. [acc.org]

Prognosis depends on the ability of the RV to maintain its function in the face of increased afterload (2). [imaging.onlinejacc.org]

Fourth, our results did not determine the prognosis of patents after discharge because we examined only dropout from inpatient treatment. [bpsmedicine.biomedcentral.com]

A very poor prognosis of PAH and a median survival of 2.8 years after diagnosis were observed. 18,19 Based on estimates obtained from the proportional-hazards (PH) models, an NIH equation was devised to predict a patient’s likelihood of survival according [ahajournals.org]

In addition, the mechanism by which anorexigens cause vascular disease has relevance to the etiology and treatment of pulmonary and systemic hypertension. Recent discoveries have clarified how the anorexigens cause vasoconstriction and hypertension. [ncbi.nlm.nih.gov]

[…] challenging entity that affects 10-52 adults per million. 1 From a hemodynamic perspective, PAH is characterized by the presence of elevated mean pulmonary artery pressures 25 mm Hg in the setting of a normal pulmonary capillary wedge pressure 2 The etiology [acc.org]

In 1996, the report of the International Primary Pulmonary Hypertension Study (IPPHS) indicted anorexigens, particularly fenfluramine or its congener, dexfenfluramine, as etiological agents. 30 The report, based on case-control epidemiological studies [doi.org]

Epidemiologic studies showed that amphetaminic anorexiants - as well as fenfluramine which has serotoninomimetic properties - could, especially in prolonged use, elicit pulmonary arterial hypertension, rare but severe adverse effect, as well as alteration [pharmacorama.com]

Articles include: Epidemiology of Pulmonary Arterial Hypertension, Pathology of Pulmonary Hypertension, Genetics of Pulmonary Arterial Hypertension, Diagnosis of Pulmonary Arterial Hypertension, Pulmonary Hypertension Owing to Left Heart Disease, Pulmonary [books.google.ro]

Author Affiliations From the Centre for Clinical Epidemiology and Community Studies, McGill University and Sir Mortimer B. [doi.org]

This is probably related to the primary pathophysiologic characteristics of the illness but could also reflect secondary functional and anatomic alterations of the brain. [ncbi.nlm.nih.gov]

These 3 factors may contribute to dyssynchronous RV wall motion with several pathophysiological mechanisms. [imaging.onlinejacc.org]

The pathophysiologic mechanism in patients with ergot-alkaloid–induced valve disease has not been established, but the similar chemical structures of serotonin, methysergide, and ergotamine may provide a clue. 16 Ergotamine-induced and carcinoid valve [oadoi.org]

Adiposopathy represents a unified, pathophysiologic process that is a root cause of metabolic diseases such as Type 2 diabetes mellitus, high blood pressure and dyslipidemia [10] Bays H. [doi.org]

Similarly, i.c.v. administration of neurotensin prevents only the orexigenic effect of MCH, but does not prevent the appetite-stimulating effect of NPY. [ncbi.nlm.nih.gov]

Roles of pharmacists, doctors and nurses and the prevention of the abuse of anorectic drugs: To prevent the misuse and abuse of anorectic drugs, the roles of the health professionals are indispensable. [scialert.net]

Understanding the mechanisms by which protein suppresses appetite may establish targets for more acceptable interventions to treat or prevent obesity. [endocrine-abstracts.org]