Anorexia nervosa is an eating disorder characterized by a pathological fear of weight gain and usually excessive weight loss. There are two subtypes of anorexia nervosa: restricting type and binge eating–purging type.
Presentation
Anorexia nervosa patients present physical symptoms as well as behavioural and emotional symptoms.
Physical signs and symptoms of anorexia are [7]:
- Severe weight loss
- Emaciated appearance
- Extreme fatigue
- Insomnia
- Dizziness or fainting
- Bluish discoloration of the fingers
- Weak hair
- Amenorrhea
- Dry skin
- Extreme discomfort in cold conditions
- Bradycardia or tachycardia
- Hypotension
- Dehydration
- Edema
- Osteoporosis
Emotional and behavioural symptoms associated with anorexia nervosa include:
- Rejection of meals
- Hiding hunger
- Excessive fear of gaining weight
- Dishonesty when discussing how much food has been consumed
- Frequent, strenuous, or compulsive exercise
- Signs of social withdrawal
- Constant experimentation with food
- Irritability
- Constant display of uninterest
- Lack of interest in sexual activities
- Use of herbal products, laxatives, etc.
Entire Body System
- Anorexia
AN Anorexia Facts & Statistics Types of Anorexia Anorexia Symptoms Long-Term Anorexia Complications Causes of Anorexia How to Treat Anorexia Anorexia Definition Anorexia Nervosa is characterized by the National Institute of Mental Illness as individuals [eatingdisorderhope.com]
Certain factors increase the risk of anorexia, including: Genetics. Changes in specific genes may put certain people at higher risk of anorexia. [mayoclinic.org]
Anorexia nervosa Other names Anorexia "Miss A—" depicted in 1866 and in 1870 after treatment. She was one of the earliest case studies of anorexia. From the published medical papers of William Gull. [en.wikipedia.org]
Anorexia nervosa is an eating disorder that can result in severe weight loss. A person with anorexia is preoccupied with calorie intake and weight. [healthline.com]
- Weight Loss
Although there are no lab tests to specifically diagnose anorexia, the doctor might use various diagnostic tests, such as blood tests, to rule out physical illness as the cause of the weight loss, as well as to evaluate the effects of the weight loss [webmd.com]
Appearance and body image symptoms Dramatic weight loss. Rapid, drastic weight loss with no medical cause. Feeling fat, despite being underweight. [helpguide.org]
Anorexia nervosa is a medical and psychological disorder classically seen in young women who present with significant weight loss, a distorted body image, and an intense fear of gaining weight despite being underweight. [ncbi.nlm.nih.gov]
- Underweight
Intense fear of gaining weight or becoming fat, even though underweight. [nationaleatingdisorders.org]
Persons with anorexia nervosa have low body weight and distorted body image, and often deny that they are dangerously underweight. [jamanetwork.com]
These patients also may carry a heavier psychological burden than those who are underweight, due to heightened preoccupations with food avoidance and more negative feelings about body shape and weight. [sciencedaily.com]
Anorexia nervosa is a medical and psychological disorder classically seen in young women who present with significant weight loss, a distorted body image, and an intense fear of gaining weight despite being underweight. [ncbi.nlm.nih.gov]
- Malnutrition
Malnutrition, Severe Weight Loss, Extreme Weight Loss) Progression of Anorexia Nervosa (Self-Starvation, Malnutrition, Severe Weight Loss, Extreme Weight Loss) Symptoms of Anorexia Nervosa (Self-Starvation, Malnutrition, Severe Weight Loss, Extreme [myvmc.com]
Pathology was consistent with liver injury secondary to severe malnutrition rather than from refeeding syndrome. [ncbi.nlm.nih.gov]
- Anemia
Other medical complications included pericardial tamponade that was treated with an open window pericardiocentesis, hepatitis, and anemia. [ncbi.nlm.nih.gov]
Other medical conditions may also be present, such as anemia, dry skin and scalp, osteoporosis, lowered body temperature and blue fingertips, and slow thinking due to brain shrinkage. [emilyprogram.com]
[…] dull, and dry hair, skin, and nails Cold intolerance/hypothermia Fatigue/dizziness/fainting Abuse of laxatives, diet pills, and/or diuretics Excessive and compulsive exercise regimes Control issues Sleep difficulties (May Include) Low blood pressure Anemia [allianceforeatingdisorders.com]
Difficulties concentrating Abnormal laboratory findings (anemia, low thyroid and hormone levels, low potassium, low blood cell counts, slow heart rate) Dizziness Fainting/syncope Feeling cold all the time Sleep problems Menstrual irregularities—amenorrhea [nationaleatingdisorders.org]
Hematological (blood): About one-third of anorexic adolescents have mild anemia (low red blood cell count). Leukopenia (low white blood cell count) occurs in up to 50 percent of anorexic adolescents. [childrenshospital.org]
Gastrointestinal
- Vomiting
There are two types of anorexia nervosa: Restricting type: People limit how much they eat but do not regularly binge eat or purge—for example, by making themselves vomit (called self-induced vomiting) or taking laxatives. Some exercise excessively. [msdmanuals.com]
They may control calorie intake by vomiting after eating or by misusing laxatives, diet aids, diuretics or enemas. They may also try to lose weight by exercising excessively. [mayoclinic.org]
Self-induced vomiting and purging are secondary devices used by the patients to counteract the effects of overeating and prevent a gain in weight. [ncbi.nlm.nih.gov]
Some people with the disorder also exercise compulsively, purge via vomiting and laxatives, and/or binge eat. Anorexia can affect people of all ages, genders, sexual orientations, races, and ethnicities. [nationaleatingdisorders.org]
- Constipation
Makes frequent comments about feeling “fat” or overweight despite weight loss Complains of constipation, abdominal pain, cold intolerance, lethargy, and/or excess energy Denies feeling hungry Develops food rituals (e.g., eating foods in certain orders [nationaleatingdisorders.org]
[…] making expected developmental weight gains Thin appearance Abnormal blood counts Fatigue Insomnia Dizziness or fainting Bluish discoloration of the fingers Hair that thins, breaks or falls out Soft, downy hair covering the body Absence of menstruation Constipation [mayoclinic.org]
They include: Anaemia (iron deficiency) Compromised immune system (e.g. getting sick more often) Intestinal problems (e.g. abdominal pain, constipation, diarrhoea) Loss or disturbance of menstruation in girls and women Increased risk of infertility in [nedc.com.au]
- Abdominal Pain
pain headaches or problems sleeping feeling cold, dizzy or very tired poor circulation in hands and feet dry skin, hair loss from the scalp, or fine downy hair (lanugo) growing on your body reduced sex drive People with anorexia often have other mental [www2.hse.ie]
Makes frequent comments about feeling “fat” or overweight despite weight loss Complains of constipation, abdominal pain, cold intolerance, lethargy, and/or excess energy Denies feeling hungry Develops food rituals (e.g., eating foods in certain orders [nationaleatingdisorders.org]
pain Dry or yellowish skin Intolerance of cold Irregular heart rhythms Low blood pressure Dehydration Swelling of arms or legs Eroded teeth and calluses on the knuckles from induced vomiting Some people who have anorexia binge and purge, similar to individuals [mayoclinic.org]
- Loss of Appetite
Anorexia means a loss of appetite or the inability to eat, and it can be a symptom of various diseases. [medicalnewstoday.com]
Extreme weight loss in people with anorexia nervosa can lead to dangerous health problems and even death. The term anorexia literally means "loss of appetite." [my.clevelandclinic.org]
The term anorexia nervosa has both Greek and Latin roots: an meaning no, and orexis meaning appetite, both from Greek, and nervosa from Latin, meaning nervous – in other words, loss of appetite due to psychological reasons. [irishtimes.com]
- Nausea
[…] prolapse, abnormal heart rhythms or heart failure Bone loss (osteoporosis), increasing the risk of fractures Loss of muscle In females, absence of a period In males, decreased testosterone Gastrointestinal problems, such as constipation, bloating or nausea [mayoclinic.org]
Apart from inducing nausea, high PYY levels were also found to be associated with decreased body weight, body mass index and bone composition in subjects with anorexia. [garvan.org.au]
[…] any mental disorder. (1, 5 ) Starvation is a major cause of death, but one in five anorexia deaths is due to suicide. (4,2) Other complications include: Organ damage Anemia Heart problems Bone loss Stomach issues, such as bloating, constipation, or nausea [everydayhealth.com]
Nausea swelled in my stomach. I thought I was going to throw up but there was nothing in my stomach to throw up. My vision became distorted like I was surrounded by funhouse mirrors. Then, the strangest thing happened. [montenido.com]
Jaw & Teeth
- Parotid Swelling
[…] mm Hg decrease in systolic BP or a 10 mm Hg decrease in diastolic BP within 3 minutes of standing from a supine position.12 Other notable findings include hypercarotenemia, acrocyanosis, lanugo, dependent edema, breast atrophy, scaphoid abdomen, and parotid [journals.lww.com]
Cardiovascular
- Hypotension
Vitals on presentation were notable for hypothermia, hypotension, and bradycardia. Initial exam was significant for emaciation, lethargy, and lower extremity edema. [ncbi.nlm.nih.gov]
Hypotension and orthostatic change in pulse and blood pressure are key indicators for hospitalization for adolescents with eating disorders. 14 A study by Hudson et al 19 suggests hospitalization when systolic blood pressure is less than 80 mm Hg. [cfp.ca]
Physical ( for nasogastric resuscitation ) Bradycardia (< 50 bpm) Postural hypotension (fall in systolic BP lying to standing > 20 mmHg) Dehydration Hypothermia (temp. [rch.org.au]
- Tachycardia
This prolongation, together with the presence of bradycardia, is a risk factor for ventricular arrhythmia due to torsade de pointes polymorphic ventricular tachycardia, and thus constitutes a risk factor for sudden death. [revespcardiol.org]
[…] dysmorphia Along with these, numerous signs may be observed and they include - but are not limited to - the following: lanugo hair and/or alopecia amenorrhea (from suppression of the gonadal axis) dental caries (from purging) orthostatic hypotension or tachycardia [radiopaedia.org]
Physical signs and symptoms of anorexia are: Severe weight loss Emaciated appearance Extreme fatigue Insomnia Dizziness or fainting Bluish discoloration of the fingers Weak hair Amenorrhea Dry skin Extreme discomfort in cold conditions Bradycardia or tachycardia [symptoma.com]
Associated arrhythmias include: sinus arrest, wandering atrial pacemakers, nodal escape beats, supraventricular tachycardia, and ventricular tachycardia. [academic.oup.com]
- Orthostatic Hypotension
hypotension or tachycardia resting bradycardia halitosis lagophthalmos purpurae 2 Central nervous system Complications include global cerebral atrophy, subacute combined degeneration of the cord due to vitamin B 12 deficiency, Wernicke encephalopathy [radiopaedia.org]
Patients with anorexia nervosa are also more susceptible to orthostatic hypotension, bradycardia, and muscle cramping due to malnutrition and low level caloric diets. [physio-pedia.com]
CVS 1.Cardiomyopathy 2.Mitral valve prolapse 3.Supraventricular and ventricular dysrhythmias 4.Long QT syndrome 5.Bradycardia 6.Orthostatic hypotension 7.Shock due to congestive heart failure 23. [slideshare.net]
Consider admission for persistent and recurrent emesis alone (10 to 20 times a day), especially in the face of bradycardia or orthostatic hypotension. [acphospitalist.org]
During her first 3 days, DX's weight increased to 41.2 kg (90.64 lb) and her orthostatic hypotension and lab results remained stable. On day 3, DX began eating solid nutrition equivalent to 2,000 calories/day. [journals.lww.com]
- Acrocyanosis
PHYSICAL FEATURES • Cardiac and skeletal systems are most affected • Constipation • Amenorrhea • Vital signs: bradycardia, hypotension, and mild hypothermia • Lanugo hair in back, forearm and cheeks • Salivary gland enlargement • Acrocyanosis of the digits [slideshare.net]
[…] hypotension, bradycardia, hypothermia, and orthostatic changes greater than a 20 mm Hg decrease in systolic BP or a 10 mm Hg decrease in diastolic BP within 3 minutes of standing from a supine position.12 Other notable findings include hypercarotenemia, acrocyanosis [journals.lww.com]
Examination can be normal but findings could include bradycardia, hypotension, peripheral oedema, gaunt face, lanugo hair, scanty pubic hair, and acrocyanosis (hands or feet are red or purple). [patient.info]
Involvement Individuals with anorexia nervosa may exhibit but are not limited to the systemic complications listed below: Cardiovascular Complications [2] Bradycardia Orthostatic Hypotension Decreased myocardial contractility Delayed capillary refill Acrocyanosis [physio-pedia.com]
Dermatological complications include lanugo, acrocyanosis, and thinning hair [10]. [intechopen.com]
Musculoskeletal
- Osteoporosis
Subchondral insufficiency fracture (SIF) is a fragility fracture secondary to osteoporosis that leads to collapse of the femoral head with no evidence of osteonecrosis. [ncbi.nlm.nih.gov]
Having an eating disorder, like anorexia nervosa, can increase your risk of osteoporosis and broken bones. [theros.org.uk]
Weight restoration with re-feeding techniques is essential for prevention of sequelae, such as heart failure, fertility problems, and osteoporosis. Patients are often identified through family intervention and the patient's non-specific complaints. [bestpractice.bmj.com]
[…] include: brittle hair and nails dry or yellowing skin feeling cold easily a soft downy hair growing all over your body irregular heartbeat, which can increase your risk of having a heart attack difficulty with concentration and memory development of osteoporosis [au.reachout.com]
- Muscular Atrophy
She was admitted to a highly specialised eating disorder facility with distended abdomen, muscular atrophy, ulcerative dermatitis, electrolyte derangements and low serum albumin. [ncbi.nlm.nih.gov]
Skin
- Lanugo
INTEGUMENTARY 1.Dry skin and hair 2.Hair loss 3.Lanugo hair/hypertrichosis 27. HEMATOLOGY 1.Anemia 2.Leukopenia 3.Thrombocytopenia 28. REPRODUCTION 1.Infertility 2.Low-birth-weight 29. [slideshare.net]
[…] include: anxiety, mood swings, depression irritable weak, lack of energy dizzy, headaches low blood pressure stomach or intestinal problems low body temperature loss of bone density hair loss or thinning soft, fine hair that grows on the face and body (lanugo [keltyeatingdisorders.ca]
Muscle loss and weakness Abnormally slow and/or irregular heartbeat Irregular menstruation or Amenorrhea Heart damage Weak or brittle bones/osteoporosis Dehydration/kidney failure Edema (swelling) Memory loss/disorientation Growth of fine, downy hair (lanugo [allianceforeatingdisorders.com]
[…] the risk for osteoporosis/osteopenia increases as bone density decreases Muscle loss and weakness Dehydration (which can result in kidney failure) Fainting, fatigue, and overall weakness Dry hair and skin, hair loss Growth of a downy layer of hair (lanugo [magnolia-creek.com]
[…] your periods not starting (in younger women and girls) bloating, constipation and abdominal pain headaches or problems sleeping feeling cold, dizzy or very tired poor circulation in hands and feet dry skin, hair loss from the scalp, or fine downy hair (lanugo [www2.hse.ie]
- Dry Skin
Physical symptoms can include: absence of regular menstrual cycles dry skin low pulse rate, and low blood pressure Behavioral changes commonly occur such as: social withdrawal irritability moodiness, and depression Without treatment, this disorder can [aacap.org]
Other medical conditions may also be present, such as anemia, dry skin and scalp, osteoporosis, lowered body temperature and blue fingertips, and slow thinking due to brain shrinkage. [emilyprogram.com]
skin, hair loss from the scalp, or fine downy hair (lanugo) growing on your body reduced sex drive People with anorexia often have other mental health problems. [www2.hse.ie]
[…] period dry skin low blood pressure You may also notice behaviors such as: excessive exercise pushing food around the plate instead of eating it, or cutting food into small pieces irritability withdrawal from social activities depressed mood hunger denial [healthline.com]
- Alopecia
[…] restriction of caloric intake low body weight relative to age, sex and health unjustified fear of weight gain body dysmorphia Along with these, numerous signs may be observed and they include - but are not limited to - the following: lanugo hair and/or alopecia [radiopaedia.org]
Patients may also suffer from bone loss, dry mouth, low blood pressure, and alopecia. Female patients usually experience missing or stopped periods. All other symptoms characteristic to malnutrition may appear in a person with anorexia nervosa. [bulimia.com]
[…] loss of muscle mass listlessness, fatigue, exhaustion hypotension, or blood pressure lightheadedness or dizziness hypothermia, or low body temperature, and cold hands and feet bloated or upset stomach and constipation dry skin swollen hands and feet alopecia [medicalnewstoday.com]
- Hirsutism
Common physical findings include bradycardia, low blood pressure, hypothermia, lanugo hair or slight hirsutism, and edema. Body fat is greatly reduced. [merckmanuals.com]
Psychiatrical
- Low Self-Esteem
Anorexia nervosa results from severe maladaptive behaviors triggered by trauma, anxiety, fear, low self-esteem, and difficulty resolving conflicts. It is not due to a failure of behavior or will, nor is it easily controlled. [centerfordiscovery.com]
The most common element surrounding ALL Eating Disorders, including Anorexia, is the inherent presence of a low self esteem Anorexia Nervosa Those who are suffering with this illness have a low self-esteem and often a tremendous need to control their [something-fishy.org]
Feelings of inadequacy, low self-esteem, anxiety, anger, or loneliness also might contribute to the development of the disorder. [webmd.com]
The causes that may contribute to a person developing anorexia nervosa include: Psychological factors, such as a high level of perfectionism or obsessive-compulsive personality traits, feeling limited control in life and low self-esteem, a tendency towards [healthdirect.gov.au]
- Denial
Feelings of guilt after eating Denial of severity of low weight High levels of anxiety and/or depression Low self-esteem Self-injury Social isolation Excuses for not eating/denial of hunger Food rituals Intense, dramatic mood swings Pale appearance/yellowish [allianceforeatingdisorders.com]
[…] intake, resulting in significantly low body weight Intense fear of gaining weight or becoming fat (despite significantly low body weight) Disturbance in the experience of body weight or shape; undue influence of weight or shape on self-evaluation, or denial [magnolia-creek.com]
Disturbance in the way in which one's body weight or shape is experienced, undue influence of body weight or shape on self-evaluation, or denial of the seriousness of the current low body weight. [nationaleatingdisorders.org]
Self-denial was continued until her planned discharge; however, positive behavioural change was recorded whilst her blood showed normokalaemia for a whole week until her discharge. [ncbi.nlm.nih.gov]
Disturbance in the experience of body weight or shape, undue influence of weight or shape on self-evaluation, or denial of the seriousness of low body weight. Loss of menstrual periods in girls and women post-puberty. [studenthealth.sa.ucsb.edu]
- Preoccupation with Food
The Shape and Weight Concern items primarily loaded together on one factor, along with preoccupation with food and fear of losing control over eating, two Eating Concern items. [ncbi.nlm.nih.gov]
Preoccupation with food, body weight, and shape may also signal an eating disorder. Common eating disorders include anorexia nervosa, bulimia nervosa, and binge-eating disorder. [nimh.nih.gov]
Read Lauren's story Warning signs of anorexia nervosa Some of the more common signs and symptoms of anorexia nervosa are: Preoccupation with body shape, weight and/or appearance Intense fear of gaining weight Preoccupation with food or food related activities [eatingdisorders.org.au]
The signs and symptoms of anorexia nervosa can include: sudden or significant weight loss sudden or significant reduction in amount of food eaten or in types of foods eaten loss of menstrual period preoccupation with food and weight weight and body shape [healthywa.wa.gov.au]
- Compulsive Behavior
Also eating disorder-specific cognitions and compulsive behaviors remitted. Previous studies have applied much lower doses and showed no effect of dronabinol upon the urge to be physically active. [ncbi.nlm.nih.gov]
The restrictive eating behaviors associated with anorexia may therefore result from an imbalance between inhibitory and reward systems, which leads to a shift to compulsive behaviors. [brainblogger.com]
behavior irritability over-exercising Food and eating become associated with guilt. [medicalnewstoday.com]
Neurologic
- Lethargy
Initial exam was significant for emaciation, lethargy, and lower extremity edema. Laboratory work-up revealed markedly elevated LFTs, hypoglycemia, thrombocytopenia and elevated INR and lipase. ECG showed sinus bradycardia with prolonged QTc. [ncbi.nlm.nih.gov]
Inability to maintain normal body weight for age and height, failure to grow as expected • Loss or disturbance of menstruation • Fainting or dizziness • Sensitivity to the cold • Bloating, constipation, or the development of food intolerances • Fatigue or lethargy [nedc.com.au]
Makes frequent comments about feeling “fat” or overweight despite weight loss Complains of constipation, abdominal pain, cold intolerance, lethargy, and/or excess energy Denies feeling hungry Develops food rituals (e.g., eating foods in certain orders [nationaleatingdisorders.org]
Extreme fear of becoming fat Excessive physical activity Denial of hunger Fixation with food preparation Unusual eating behaviors Physical symptoms can include: Poor nutritional status Dehydration Being very thin Stomach pain or bloating Constipation Lethargy [hopkinsmedicine.org]
Urogenital
- Amenorrhea
KEYWORDS: Anorexia nervosa; Bone metabolism; Hypothalamic amenorrhea; Low bone density [ncbi.nlm.nih.gov]
Amenorrhea: The illness also causes a woman's menstrual cycle to stop, a condition called amenorrhea. Impotence: Men with anorexia often become impotent. [pamf.org]
Endocrine (hormones): One of the most telling symptoms of anorexia is amenorrhea, or when the menstrual cycle is missed for three or more consecutive cycles without any other underlying cause. [childrenshospital.org]
It most commonly affects young women and can lead to amenorrhea, malnutrition, brittle bones, and other physiological changes. anorexia nervosa a disorder characterized by a prolonged refusal to eat, resulting in emaciation, amenorrhea, emotional disturbance [medical-dictionary.thefreedictionary.com]
- Kidney Failure
failure infertile, unable to get pregnant dry, yellow skin joint pain swollen hands or feet insomnia (for girls and women) irregular or no menstrual periods AN can lead to many medical problems. [keltyeatingdisorders.ca]
failure Edema (swelling) Memory loss/disorientation Growth of fine, downy hair (lanugo) Decreased growth hormone which may lead to delayed physical maturation Decreased estrogen/testosterone/thyroid hormone Infertility Electrolyte imbalance that can [allianceforeatingdisorders.com]
[…] increases as bone density decreases Muscle loss and weakness Dehydration (which can result in kidney failure) Fainting, fatigue, and overall weakness Dry hair and skin, hair loss Growth of a downy layer of hair (lanugo) all over the body, including the [magnolia-creek.com]
Severe dehydration, which can result in kidney failure. Fainting, fatigue and overall weakness. Dry hair and skin; hair loss. Growth of a downy layer of hair called lanugo all over the body, including the face. [pbs.org]
- Irregular Menstruation
[…] heartbeat Irregular menstruation or Amenorrhea Heart damage Weak or brittle bones/osteoporosis Dehydration/kidney failure Edema (swelling) Memory loss/disorientation Growth of fine, downy hair (lanugo) Decreased growth hormone which may lead to delayed [allianceforeatingdisorders.com]
[…] or irregular menstruation Constipation Irregular heart rhythms Dehydration and electrolyte imbalances Frequent feeling of cold Receiving Anorexia Treatment: What to Do After Recognizing Anorexia Symptoms Eating disorders, especially anorexia, often develop [mccallumplace.com]
Visible signs that she is starving herself include extreme weight loss, abnormal thinness, brittle nails, hair loss, constipation, irregular menstruation, and swelling. [childmind.org]
Pale complexion (almost a pasty look) Physical/Medical Complications Fatigue and lack of energy Amenorrhea (loss of menstruation) Skin problems Dizziness and headaches Dehydration Shortness of breath Irregular heartbeats Cold hands and feet Bloating [mirror-mirror.org]
- Secondary Amenorrhea
Anorexia nervosa Treatment of secondary amenorrhoea and infertility Secondary amenorrhea is a hallmark of anorexia nervosa. [jeatdisord.biomedcentral.com]
Endocrine symptoms in anorexia nervosa include hypothermia (feeling cold), delayed onset of menses or secondary amenorrhea, and osteopenia progressing to osteoporosis. 11, 12 More than one-half of patients with eating disorders meet criteria for a current [aafp.org]
The continuous downward spiraling of weight loss then causes secondary amenorrhea and loss of secondary sexual characteristics, further worsening weight loss. [emedicine.medscape.com]
- Sexual Dysfunction
Partners may become more anxious to conceive, increasing sexual dysfunction.[17] Marital discord often develops, especially when they are under pressure to make medical decisions. [en.wikipedia.org]
Workup
Although there is no clear evidence to show that any particular treatment for anorexia nervosa works better than others, evidence shows that early intervention and treatment often prove effective in handling of the condition [9]. In general, anorexia nervosa treatment is focused on addressing these three main areas:
- Restoration of the individual to a healthy weight
- Treatment of psychological disorders related to the ailment
- Reduction or eradication of behaviours responsible for the disorder in the first instance
X-Ray
- Delayed Bone Age
[medical citation needed] Height potential is normally preserved if the duration and severity of illness are not significant or if the illness is accompanied by delayed bone age (especially prior to a bone age of approximately 15 years), as hypogonadism [en.wikipedia.org]
Serum
- Calcium Decreased
[…] little data that supplementation of calcium decreases the risk of fractures.[99] While some meta-analyses have found a benefit of vitamin D supplements combined with calcium for fractures, they did not find a benefit of vitamin D supplements (800 IU/ [en.wikipedia.org]
QT, RR, ST Intervals
- Prolonged QT Interval
Cooke et al9 analyzed the QT interval in 41 adult patients and showed a prolonged QT interval in 15% of the patients, with sudden death occurring in two. [revespcardiol.org]
An ECG may show bradycardia or a prolonged QT interval in those with more severe anorexia. [patient.info]
Prolonged QT intervals may increase the risk for cardiac dysrhythmias and sudden death.14,15 The gastrointestinalsystem is affected as well, including possible dysphagia from weakened and uncoordinated pharyngeal muscles, slowed gastric emptying, and [journals.lww.com]
Some patients have prolonged QT intervals (even when corrected for heart rate), which, with the risks imposed by electrolyte disturbances, may predispose to tachyarrhythmias. Sudden death, most likely due to ventricular tachyarrhythmias, may occur. [merckmanuals.com]
Treatment
Treatment of this condition requires a physical, social and psychological assessment of the individual by health professionals, especially an eating disorder specialist. This assessment is important to decide the most suitable care plan to follow.
Generally, treatment of the condition will involve a combination of psychological therapy and individually tailored advice on eating and nutrition. This will help the patient gain weight safely.
Psychiatrists, specialist nurses and dietitians contribute at different stages to the treatment of anorexic individuals. The treatment is done on an outpatient basis except in serious cases where the individual must be treated in a hospital or specialist eating disorder clinics.
Prognosis
The prognosis of anorexia nervosa varies. Morbidity rates often range from 10 to 20% with only 50% of patients being able to recover fully. Of the remaining, 20% remain emaciated while another 25% still present thin body. The remaining either dies of starvation or become overweight [6].
However, mortality following complications as a result of starvation is far less frequent in patients with anorexia nervosa as death arising from suicide which is the chief source of mortality incidence. Suicide attempts are higher in people with a history of artificial inducement of physical pain, drug use, and laxative use.
Etiology
Anorexia nervosa is as a result of a complex interchange between social biologic and psychological factors [3]. It affects more women than men and in women it is mostly seen in adolescents.
Patients who develop anorexia nervosa often display a relatively high incidence of premorbid anxiety disorders. Since most cases of anorexia nervosa are seen within the pubescent years, experts believe that exertion of control over body weight and food consumption is the adolescents attempting to make up for what is seen as absence of selfhood and autonomy.
Some predisposing factors in eating disorders include:
- Female sex
- Difficulty discussing negative emotions
- Low self-esteem
- Family history of any kinds of eating disorders
- Perfectionistic personality
- Difficulty resolving conflict
Maternal encouragement of weight loss (actively or passively) is also a risk factor for anorexia nervosa especially when the disorder is seen in children. The possibility of genetic predisposition has been pointed out following reported cases of anorexia nervosa in twins and triplets.
In individuals with anorexia nervosa, there is a lifelong incidence of anxiety, depressive disorders as well as obsessive-compulsive disorder. Systemic lupus eythematosus and congenital adrenal hyperplasia are common disorders associated with anorexia nervosa.
Epidemiology
The condition is seen in all developed countries and cuts across all socioeconomic classes. It occurs worldwide around the same rates of incidence of 0.3 to 1% in women and 0.1 to 0.3% in men. It is also seen in developing countries like China and Brazil [4].
Pathophysiology
A standard case of anorexia begins with a young individual mildly overweight or normal weight going on a diet or exercise regime with a plan to lose weight. Following the initial positive results, he or she receives compliments from peers or family. This is deemed high reward by the individual and makes it difficult for them to stop this behaviour as soon as an ideal weight is achieved [5].
Malnutrition as a result of self-starvation brings about protein deficiency and a disruption of multiple organ systems including the cardiovascular, renal, gastrointestinal, neurologic, endocrine, integumentary, reproductive and hematologic systems.
Prevention
There's no guaranteed way to prevent anorexia nervosa or other forms of eating disorders [10].
Summary
Anorexia nervosa refers is an eating disorder where patients try their best to keep their body weight as low as they can [1]. They achieve this by severely restricting the amount of food they eat and vomiting after meals. They also engage in excessive exercising.
This condition develops as a result of anxiety about the shape of the body and weight and fear of becoming fat. Anorexic individuals often have a false image of themselves [2]. This makes they feel they are fat when in reality, they may be perfectly normal.
Anorexia is seen both sexes and peak age for the condition is 16 to 17 years.
Patient Information
Anorexia nervosa refers to an eating disorder which causes people be overly obsessed with their weight and what they consume. In such people, the focus is on trying to maintain body weight that is well below what is deemed normal for their height and age and they achieve this by starving themselves or exercising excessively.
People who have this problem make the mistake of equating thinness with self-worth.
This condition is difficult to overcome but with the right treatment and psychotherapy, the individual can return to a normal eating habit and also reverse any damages already caused by the condition.
References
- Miller KK, Grinspoon SK, Ciampa J, Hier J, Herzog D, Klibanski A. Medical findings in outpatients with anorexia nervosa. Arch Intern Med. Mar 14 2005;165(5):561-6.
- Eisler I, Simic M, Russell GF, Dare C. A randomised controlled treatment trial of two forms of family therapy in adolescent anorexia nervosa: a five-year follow-up. J Child Psychol Psychiatry. Jun 2007;48(6):552-60.
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