The authors report a young infant who presented with failure to thrive and recurrent respiratory tract infections. The patient had bilaterally absent pinnae; instead small skin tags were present. [ncbi.nlm.nih.gov]

Anotia/Microtia: People of Anotia syndrome usually born without the presence of external ear, while in Microtia small portion of external ear is present, or the incompletely formed external ear is present. [imedpub.com]

According to my classification, patients with anotia always present with imbalanced facial asymmetry caused by undevelopment of the bones of the face and skull as well as of the soft tissues. [link.springer.com]

Therefore, microtia and anotia shall be considered reconstructive surgery to restore a missing or significantly deformed body part visibly present under normal circumstances. [entnet.org]

• Weakness

  Your simple wisdom helped the weak and the poor. Your lesson - to conquer jealousy and anger in yourself and then in those, who will select you as their guide. You should understand that these weaknesses are caused by fear and self-regret. [names.org]

  His patients had congenital heart disease associated with unilateral weakness of only the lower portion of the face. [indianjotol.org]

• Developmental Delay

  We reported a 2-year-old boy with developmental delay, mild mental retardation, and severe craniofacial malformation, including facial asymmetry with hypoplasia of the left zygoma, maxilla, and mandible, and left anophthalmia and anotia. [ncbi.nlm.nih.gov]

  Other associations include Treacher Collins' syndrome, Nager and CHARGE syndrome ( C oloboma, H eart defects, A tresia of the choanae, R estriction of growth and developmental delay, G enitourinary abnormalities, E ar anomalies), among others. [patient.info]

  Your baby’s provider checks your baby for language and developmental delays as he grows and may suggest therapy. Speech-language therapy is the treatment for kids with speech or language disorders. [marchofdimes.org]

• Asymmetry of the Ears

  Case Report A 2-day-old male newborn born out of nonconsanguineous parentage, full term normal vaginal delivery, who cried immediately after birth, was found to have facial asymmetry with absent ears. [ncbi.nlm.nih.gov]

  A 2-day-old male newborn born out of nonconsanguineous parentage, full term normal vaginal delivery, who cried immediately after birth, was found to have facial asymmetry with absent ears. [pediatricneurosciences.com]

• Suggestibility

  Downslanting palpebral fissures, small jaw, eyelid coloboma – suggests selected syndromes. Cervical vertebral anomalies suggests OAVS (check for radiographs). Hearing evaluation. Genetic or chromosomal testing. [cdc.gov]

  A hearing aid may be suggested and/or surgery may be performed to construct external ear structures. Depending upon the level of defect, surgery is often performed on sufferers between the ages of four and ten. [sexner.com]

  The analysis of pedigrees and familial cases suggests an autosomal dominant trait with variable expression and incomplete penetrance in a proportion of cases, or a multifactorial aetiology. [ncbi.nlm.nih.gov]

• Distractibility

  […] include Facial nerve rehabilitation; Septorhinoplasty; Vascular lesions; Craniofacial anomalies; Free tissue transfer; Craniomaxillofacial trauma; Cleft lip and palate; Surgical speech disorders; Otoplasty; Microtia; Soft tissu trauma and scar revision; Distraction [books.google.ro]

  The main symptoms are distractibility, impulsivity, hyperactivity, and often trouble organizing tasks and projects, difficulty going to sleep, and social problems from being aggressive, loud, or impatient. [rarediseases.oscar.ncsu.edu]

• Speech Disorder

  Topics include Facial nerve rehabilitation; Septorhinoplasty; Vascular lesions; Craniofacial anomalies; Free tissue transfer; Craniomaxillofacial trauma; Cleft lip and palate; Surgical speech disorders; Otoplasty; Microtia; Soft tissu trauma and scar [books.google.ro]

  May be associated with hearing loss and secondary speech disorder. [sonoworld.com]

  Speech-language therapy. Your baby’s provider checks your baby for language and developmental delays as he grows and may suggest therapy. Speech-language therapy is the treatment for kids with speech or language disorders. [marchofdimes.org]

• Language Delays

  Delayed speech development, Speech delay, Language delay, Speech difficulties, Delayed speech, Delayed speech acquisition, Late-onset speech development, Speech and language delay, Delayed language development [more] A degree of language development [rarediseases.oscar.ncsu.edu]

  In cases of bilateral microtia, the child will have significant speech and language delays if the hearing loss is left untreated. [everydayhearing.com]

• Delayed Speech and Language Development

  Delayed speech development, Speech delay, Language delay, Speech difficulties, Delayed speech, Delayed speech acquisition, Late-onset speech development, Speech and language delay, Delayed language development [more] A degree of language development [rarediseases.oscar.ncsu.edu]

Reconstructive surgery is appropriate as a primary treatment in both children and adults. [entnet.org]

Regarding microtia, there are several different modes of treatment. [letdowsrasac.tk]

Prognosis of Anotia Prognosis of Anotia differs from one patient to another. Prognosis is good if the child is treated in his/her early childhood. [epainassist.com]

Prognosis for patients with anotia is generally very good when treated in early childhood. When anotia is an isolated condition, patients can typically lead normal lives after treatment. [earwells.com]

Anotia Prognosis The outcome of the condition differs from one child to another. Treating the disorder during the early childhood of patients helps to get a better outcome. [hxbenefit.com]

Traumatic facial palsy in neonates carries good prognosis as compared to developmental facial palsy that carries poor functional outcome. Conclusion CFP can be developmental or acquired. [ncbi.nlm.nih.gov]

Etiology : Autosomal dominant inheritance in some cases [6]. Pathogenesis : unknown. [sonoworld.com]

Additional study for factors associated with these characteristics could reveal clues for the etiology of these ear anomalies. [ncbi.nlm.nih.gov]

Our findings point to some potentially modifiable risk factors and provide further leads toward understanding the etiology of anotia/microtia. [jhu.pure.elsevier.com]

The etiology of microtia and the cause of this wide variability in In this paper we review current knowledge of the epidemiology and genetics of microtia, In this paper, the term “microtia” includes anotia as the most severe. Microtia & Atresia. [letdowsrasac.tk]

Anotia Prevention In most cases, it is not possible to prevent the disorder due to its unknown etiology. However, avoiding the use of thalidomide during pregnancy can help lower the risk of having the condition for an unborn baby. [hxbenefit.com]

Highly Cited 1995 Highly Cited 1995 Epidemiology and genetics of microtia-anotia: a registry based study on over one million births. [semanticscholar.org]

BACKGROUND: There is a paucity of epidemiologic information about the external ear malformations anotia and microtia. [ncbi.nlm.nih.gov]

We examined the association between selected Hispanic ethnicity and acculturation factors and anotia/microtia in the National Birth Defects Prevention Study. [ncbi.nlm.nih.gov]

This work has been released into the public domain by its author, Centers for Disease Control and Prevention, National Center on Birth Defects and Developmental Disabilities. This applies worldwide. [commons.wikimedia.org]

Study 30928866 2019 43 Selected acculturation factors and birth defects in the National Birth Defects Prevention Study, 1997-2011. 62 Hoyt AT...National Birth Defects Prevention Study 31021057 2019 44 Reconstruction of Congenital Microtia and Anotia: [malacards.org]

We conducted a comprehensive assessment of a wide range of potential risk factors using data from the National Birth Defects Prevention Study (NBDPS), a population-based case-control study of non-chromosomal structural birth defects in the United States [jhu.pure.elsevier.com]

CDC funds the Centers for Birth Defects Research and Prevention, which collaborate on large studies such as the National Birth Defects Prevention Study (NBDPS; births 1997-2011) and the Birth Defects Study To Evaluate Pregnancy exposureS (BD-STEPS; began [cdc.gov]