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Anterior Cerebral Artery Occlusion


Presentation

  • Abstract Three cases of bilateral anterior cerebral artery occlusion are presented with akinetic mutism.[ncbi.nlm.nih.gov]
  • Brain CT scan revealed the presence of mild low density foci presenting an irregular enhancement, which followed the distribution of mesial frontal gyri and paracentral lobulus, bilaterally.[ncbi.nlm.nih.gov]
  • Unique Presentation of Akinetic Mutism and Coexisting Thyroid Storm Relating to Stroke.[connection.ebscohost.com]
  • Akinetic mutism and bilateral anterior cerebral artery occlusion Abstract Three cases of bilateral anterior cerebral artery occlusion are presented with akinetic mutism.[jnnp.bmj.com]
  • Gegenhalten and grasp reflex were present bilaterally. Sensations could not be tested.[neurologyindia.com]
Vertical Gaze Palsy
  • One patient had a clear vertical gaze palsy in the upward and downward direction unaccompanied by pupillary abnormalities.[link.springer.com]
Monoplegia
  • Capsular branch occlusion (Heubner Artery ) clinical features Faciobrachial monoplegia which is proximal more than distal, i.e. involving the shoulder more than the hand.[notes.medicosnotes.com]
  • Overview Contralateral monoplegia with mild upper-extremity involvement is an unusual condition classically described as occurring when ischemia involves the anterior cerebral artery territory.[medlink.com]
Focal Seizure
  • A 49 year old former airman was admitted with history of sudden onset of loss of consciousness and right focal seizures becoming generalized. He had exertional breathlessness for two days prior to admission. He was a heavy smoker and alcoholic.[neurologyindia.com]

Treatment

  • In the latter subjects we assessed the frequency of treatment-induced anterior cerebral artery emboli.[ajnrdigest.org]
  • Access the comprehensive, expert clinical guidance you need to recognize the clinical manifestations of stroke, use the latest laboratory and imaging studies to arrive at a diagnosis, and generate an effective medical and surgical treatment plan.[books.google.com]
  • Emergency administration of abciximab for treatment of patients with acute ischemic stroke: results of an international phase III trial: Abciximab in Emergency Treatment of Stroke Trial (AbESTT-II). Stroke. 2008 Jan. 39(1):87-99. [Medline].[medscape.com]
  • Safe Treatment of Pulmonary Hypertension With Bosentan in a Patient With Moyamoya Disease and Cerebral Ischemia. Day, Ronald W.; Brockmeyer, Douglas L.; Feola, G.[connection.ebscohost.com]
  • Treatment of distal anterior cerebral artery aneurysms with the Pipeline Embolization Device. Journal of Clinical Neuroscience, 35, 133-138.[scholars.northwestern.edu]

Prognosis

  • Case series show a favorable prognosis for patients, with up to 68% of patients in one series had a modified Rankin scale score of 2 or less at discharge. [3] [4] [6] With regards to specific deficits, studies suggest that aphasias from ACA infarcts tend[ncbi.nlm.nih.gov]

Etiology

  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • Etiologies: Most often embolic from heart, aorta or the internal carotid artery. Rarely, due to intrinsic atherosclerotic disease of the ACA.[casemed.case.edu]
  • In this article, the authors provide a comprehensive description of the clinical manifestations, topographical distribution, etiology, and outcome of anterior cerebral artery stroke.[medlink.com]
  • Conclusion: Anterior cerebral artery (ACA) atherosclerosis is the most important stroke etiology in our population, causing infarction with various mechanisms.[neurology.org]
  • The risk factors and etiology of strokes in this vascular territory are largely the same as for the other principal cerebral arteries including hypertension, dyslipidemias, diabetes mellitus, smoking, atherosclerosis, and cardioembolism.[ncbi.nlm.nih.gov]

Epidemiology

  • Delay in presentation and evaluation for acute stroke: Stroke Time Registry for Outcomes Knowledge and Epidemiology (S.T.R.O.K.E.). Stroke. 2001 Jan. 32(1):63-9. [Medline]. Puolakka T, Väyrynen T, Häppölä O, Soinne L, Kuisma M, Lindsberg PJ.[medscape.com]
  • The significance of this particular mechanism of infarction lies in its potential for adverse outcomes secondary to distal occlusions after an otherwise effective recanalization of an affected vessel. [10] Epidemiology Infarctions of the anterior cerebral[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Gain fresh perspectives and up-to-date insights from the world’s leading authorities on the pathophysiology, diagnosis, and management of stroke.[books.google.com]

Prevention

  • Stay up to date on hot topics such as mechanisms of action of commonly used drugs, neuronal angiogenesis and stem cells, basic mechanisms of spasm and hemorrhage, prevention of stroke, genetics/predisposing risk factors, and much more.[books.google.com]
  • A randomized trial of low-dose aspirin in the primary prevention of cardiovascular disease in women. N Engl J Med. 2005 Mar 31. 352(13):1293-304. [Medline]. [Guideline] Hughes S. New AHA/ASA Stroke Secondary Prevention Guidelines.[medscape.com]
  • Therefore, preventive treatment of cerebral arterial complication should be taken into account, especially in cases with high white blood cell count. Key Words: Acute promyelocytic leukemia · All-trans retinoic acid syndrome · Cerebral infarction[e-jnc.org]
  • Collateral circulation is not always sufficient to prevent a stroke. Some people lack one or more of the communicating arteries in the Circle of Willis.[csuchico.edu]
  • Dual antiplatelet therapy (aspirin and clopidogrel) are recommended to start within 24 hours for 21 days in patients with minor stroke for early secondary stroke prevention.[ncbi.nlm.nih.gov]

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