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Anti-p200 Pemphigoid


  • Twelve patients had atypical clinical presentation, including eczematous, urticarial, prurigo-like, dyshydrosis-like and rosette-like skin lesions. Eight patients (57%) had mucosal involvement.[ncbi.nlm.nih.gov]
  • We present an overview of the pathogenesis, clinical features, diagnosis and treatment of this new disease entity.[unboundmedicine.com]
Down Syndrome
  • This phenomenon is noted in several distinct dermatological entities, including Beçhet’s, pyoderma gangrenosum, Sweet’s syndrome, neonates with Down’s syndrome, myleoproliferative disorders, non-Hodgkin’s lymphoma, chronic myeloid leukemia treated with[ncbi.nlm.nih.gov]
  • We report here the first patient with anti-p200 pemphigoid probably provoked by oral intake of penicillin given because of prolonged cough.[medicaljournals.se]
Skin Ulcer
  • We report here a severe and refractory case of anti-p200 pemphigoid that developed in a 53-year-old woman, in which blisters led to multiple skin ulcers, followed by severe scar formation.[ncbi.nlm.nih.gov]
  • ulcers and scar formation. ( 19060472 ) 2009 18 The autoantigen in anti-p200 pemphigoid is synthesized by keratinocytes and fibroblasts and is distinct from nidogen-2. ( 17637825 ) Hofmann S.C....Bruckner-Tuderman L. 2008 19 Anti-p200 pemphigoid associated[malacards.org]
  • Goto-Ohguchi Y, Nishie W, Akiyama M et al (2009) A severe and refractory case of anti-p200 pemphigoid resulting in multiple skin ulcers and scar formation. Dermatology 218:265–271 PubMed CrossRef 24.[springermedizin.de]
  • At this time there was post-inflammatory hyperpigmentation but no scarring on the skin. During the next 3 months prednisone was tapered and withdrawn.[medicaljournals.se]
  • Minocycline-induced hyperpigmentation in patients with pemphigus and pemphigoid. Arch Dermatol. 2000;136(9):1133-8. Nagashima R, Tsuge K, Harada M, Katagiri Y, Shinzawa H, Takahashi T.[malattierare.regione.veneto.it]
  • Overlap of Bullous, Anti–Laminin-332, and Anti-p200 Pemphigoid With Concomitant Anti–Contactin-1–Positive Inflammatory Polyneuropathy Treated With Intravenous Immunoglobulins as a Manifestation of Epitope Spreading JAMA Dermatology ( IF 8.107 ) Pub Date[x-mol.com]
  • 1 Overlap of Bullous, Anti-Laminin-332, and Anti-p200 Pemphigoid With Concomitant Anti-Contactin-1-Positive Inflammatory Polyneuropathy Treated With Intravenous Immunoglobulins as a Manifestation of Epitope Spreading. ( 30892575 ) 2019 2 Case of anti-p200[malacards.org]
  • SanderAbstractThe risk of epileptic seizures seems increased in several systemic autoimmune disorders including systemic lupus erythematosus, type 1 diabetes mellitus, myasthenia gravis, celiac disease, rheumatoid arthritis, Hashimoto’s encephalopathy[medworm.com]


  • CONCLUSION: Treatment of anti-p200 pemphigoid is difficult. In our case, treatment by mycophenolate mofetil was effective and could offer an alternative to dapsone.[pesquisa.bvsalud.org]
  • We describe the clinical, histologic, and immunopathologic features in a patient with anti-p200 pemphigoid, as well as his favorable response to treatment with systemic glucocorticosteroids and dapsone.[utsouthwestern.influuent.utsystem.edu]


  • Most of the previous cases have been successfully treated using mild-to-moderate immunosuppressive therapies, which resulted in a good prognosis.[ncbi.nlm.nih.gov]
  • Many patients with anti-p200 pemphigoid had heterogeneous clinical presentation and a more severe prognosis than previously suspected.[m.eurekamag.com]
  • CONCLUSION: Many patients with anti-p200 pemphigoid had heterogeneous clinical presentation, and a more severe prognosis than previously suspected. This article is protected by copyright. All rights reserved.[medworm.com]


  • The etiology of the disease is unknown. EBA antibodies bind to type VII collagen within anchoring fibrils at the dermo-epidermal junction.[bib.irb.hr]
  • Twin research is an informative approach for understanding the genetic , environmental The historical roots of twin studies Biological Psychology. environment in the etiology of OCD include twin , adoption pdf studies 1 Department of Biological Psychology[zsvhbgwbr.ml]
  • […] blistering disorder. 1 Approximately 70 cases have been published so far. 2 Clinically, it may resemble bullous pemphigoid (BP), 1 , 2 linear IgA bullous dermatosis (LABD), 2 or dermatitis herpetiformis (DH). 3 Some cases coexisted with psoriasis. 3 - 5 The etiology[jamanetwork.com]
  • Pemphigus: Etiology, pathogenesis, and inducing or triggering factors: Facts and controversies. Clin Dermatol 2013;31:374-81. 10. Shephard M, Hodgson T, Hegarty AM. Vesiculobullous disorders affecting the oral cavity.[e-ijd.org]


  • The epidemiological features of these diseases vary substantially in different regions of the world. Observational studies investigating comorbidities and associations among patients wit...[medworm.com]
  • Epidemiological studies showed some triggers to the development of autoimmune dysregulation, e.g. drugs. Furthermore, it has been shown that genetic factors play a role in the pathogenesis of the disease.[clinicaltrials.gov]
  • Pemphigoid gestationis (if pregnant) Pemphigus Stevens-Johnson syndrome Toxic epidermal necrolysis Monitoring Epithelial basement membrane zone IgA antibody testing or epithelial skin antibodies to monitor disease activity and response to therapy Background Epidemiology[arupconsult.com]
  • Epidemiology Anti-p200 pemphigoid: 1.3% of seropositive sAIBD (unpublished) Dermal side binding by IIF SSS: 23.5% 21.6%54.9% Anti-p200 pemphigoid Anti–LN-332 MMP EBA 38.[slideshare.net]
Sex distribution
Age distribution


  • The aim of this study was to clarify the pathophysiological importance of IL-17A in BP. We found elevated numbers of IL-17A CD4 lymphocytes in the peripheral blood of BP patients and identified CD3 cells as major source of IL-17A in early BP ...[medworm.com]
  • To this end, various in vitro and animal experiments have been used to understand some basic pathophysiological mechanisms in these diseases.[clinicaltrials.gov]
  • Abstract Knowledge of the pathophysiology of immunobullous diseases has been advanced by the demonstration that passive transfer of antibodies against skin autoantigens can induce blisters in experimental animals with clinical, histologic, and immunopathologic[jci.org]
  • […] colitis , Crohn disease , gastric hypochlorhydria, thyrotoxicosis , systemic lupus erythematous , dermatomyositis , rheumatoid arthritis Malignancies Lymphoma or chronic lymphocytic leukemia (rare in both) Carcinoma of the bladder , thyroid , or esophagus Pathophysiology[arupconsult.com]
  • Important: The pathophysiology of bullous pemphigoid revolves around hemidesmosomes, while desmosomes are associated with the pathophysiology of pemphigus Vulgaris. Hemidesmosomes connect the basal keratinocytes to the basal lamina in the skin.[lecturio.com]


  • More Articles Review articles Cutaneous adverse events associated with vemurafenib in patients with metastatic melanoma: practical advice on diagnosis, prevention and management of the main treatment‐related skin toxicities Authors: R. Sinha, K.[bjdonline.com]
  • The researchers wrote that preventive therapies for pneumocystis pneumonia include trimethoprim-sulfamethoxazole, atovaquone (Mepron, GlaxoSmithKline), dapsone (Aczone, Allergan) and pentamide.[healio.com]
  • GMT TB Infection - Centers for Disease Control and Prevention - penfigoide anti p200 similar a EBA. Penfigoide De Mucosas Pdf Download shorl. Scribd is the world' s largest social reading and publishing site.[upucareryme.tk]
  • Activation of naïve B cells in the traepithelial Lymphocytes Mainly CD8 T cells represents a very large Preventing Infection pptx.[evarcofu.tk]

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