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Anticholinergic Syndrome

Presentation

At present, the ACB scale is the most popular available anticholinergic burden measurement tool. [cochranelibrary.com]

The present review article gives an overview over incidences, diagnostic and therapeutic issues of neurologic complications in operative patients, such as perioperative stroke, postoperative visual loss and the anticholinergic syndrome. [thieme-connect.com]

Entire Body System

  • Hyperthermia

    Frampton A, Spinks J: Hyperthermia associated with central anticholinergic syndrome caused by a transdermal hyoscine patch in a child with cerebral palsy. Emerg Med J 22: 678, 2005. [PubMed: 16113205] 6. [accessmedicina.mhmedical.com]

  • Collapse

    Collapse all Expand all Contexte Les médicaments aux propriétés anticholinergiques sont couramment prescrits aux personnes âgées. [cochranelibrary.com]

  • Gastric Lavage

    Salen P, Shih R, Sierzenski P, Reed J: Effect of physostigmine and gastric lavage in a Datura stramonium-induced anticholinergic poisoning epidemic. Am J Emerg Med 21: 316, 2003. [PubMed: 12898490] 46. [accessmedicina.mhmedical.com]

Cardiovascular

  • Hypertension

    A number of prognostic factors have been associated with the onset of dementia, including age, sex, premorbid intelligence, genetics, medical conditions (e.g. diabetes, hypertension), and lifestyle factors (e.g. physical inactivity) (Livingston 2017). [cochranelibrary.com]

Treatment

Beaver KM, Gavin TJ: Treatment of acute anticholinergic poisoning with physostigmine. Am J Emerg Med 16: 505, 1998. [PubMed: 9725967] 43. Teoh R, Page AV, Hardern R: Physostigmine as treatment for severe CNS anticholinergic toxicity. [accessmedicina.mhmedical.com]

In case of neurological complications in the perioperative phase an interdisciplinary approach in immediate diagnosis and treatment may prevent patients from permanent damage. [thieme-connect.com]

Use of measures of anticholinergic burden to guide treatment decisions is entering clinical practice. [cochranelibrary.com]

Prognosis

Discussing reporting deficiencies: prognosis research is frequently confounded by poor reporting and possible publication bias. [cochranelibrary.com]

Etiology

Determination of etiologic mechanisms of strokes secondary to coronary artery bypass graft surgery. Stroke. 2003; 34 2830-2834 8 Bucerius J, Gummert JF, Borger MA et al.. [thieme-connect.com]

Epidemiology

Isbister GK, Oakley P, Dawson AH, Whyte IM: Presumed Angel’s trumpet (Brugmansia) poisoning: clinical effects and epidemiology. Emerg Med (Fremantle) 15: 376, 2003. [PubMed: 14631706] 13. [accessmedicina.mhmedical.com]

Prevention

Improving anesthesiologic management based on consequent prevention measures can help to reduce the incidence of neurological complications after anesthesia. [thieme-connect.com]

Identification of modifiable prognostic factors are potential targets for preventing or delaying the onset of cognitive decline and dementia. [cochranelibrary.com]

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