Structurally, the most promising compounds (both urea and thiourea derivatives) presented smaller lateral chains and unsubstituted or para-substituted phenyl ring with a methyl group. [ncbi.nlm.nih.gov]

• Neonatal Hemorrhage

  Hemorrhagic Disease in the Neonate Hemorrhagic disease of the newborn due to vitamin K deficiency has been described after gestational use of anticonvulsant drugs especially phenobarbital and phenytoin (Davis 1970, Hill, Horning and Horning 1973) Vitamin [web.archive.org]

• Epilepsy

  Future discoveries by the ASP (now renamed the Epilepsy Therapy Screening) can be expected to make additional contributions to improving the health of persons with epilepsy. KEYWORDS: Anti-seizure; Anticonvulsant; Epilepsy; Screening; Seizure [ncbi.nlm.nih.gov]

  Alcohol and Marijuana: Effects on epilepsy and use by patients with epilepsy. Epilepsia 2001:42(10);1266-72. [bpac.org.nz]

  See separate leaflets called Living with Epilepsy and Epilepsy - Contraception/Pregnancy Issues for more details. [patient.info]

  Emeside, Zarontin, ethosuximide an anticonvulsant drug (trade names Emeside and Zarontin) used to treat petit mal epilepsy Neurontin, gabapentin an anticonvulsant (trade name Neurontin) used to control some types of seizures in the treatment of epilepsy [vocabulary.com]

• Fatigue

  Side effects can include fatigue, imbalance, and behavioral changes, which often dissipate after the first month of treatment. [healthcommunities.com]

  It curbs your pain and can help your fatigue and sleep problems. Gabapentin ( Neurontin ). Research shows this drug lessens pain and fatigue, and improves sleep. It's similar to pregabalin, and works in the same way. [webmd.com]

  Fycompa can cause dizziness, fatigue, and neuropsychiatric changes including alterations in mood, and aggression. For this reason, it contains a boxed warning. [verywellhealth.com]

  Side Effects of Anticonvulsants Dizziness Drowsiness Fatigue Tremors Rash Weight Gain Long term use leads to liver damage Confusion Nausea or vomiting Common Anticonvulsant Drugs Neurontin Tegretol Topamax Dilantin Valpropate Stop suffering from the side [recoveryconnection.org]

• Acute Intermittent Porphyria

  Safety of anticonvulsants in hepatic porphyrias. Neurology 1981;31:480-4. 7. Larson AW, Wasserstrom WR, Felsher BF, Chih JC. Posttraumatic epilepsy and acute intermittent porphyria: effects of phenytoin, carbamazepine, and clonazepam. [porphyria.eu]

• Transient Hypothyroidism

  Although both women received anticonvulsant therapy, transient hypothyroidism was observed only in the hypothyroid woman and was found after treatment with classic anticonvulsant agents (carbamazepine and sodium valproate) but not with gabapentin. [ncbi.nlm.nih.gov]

• Nausea

  All anticonvulsants have dose-dependent side effects on the central nervous system such as somnolence and nausea, but some agents have more specific side effects (e.g., gingival hyperplasia caused by phenytoin). [amboss.com]

  Common side effects include tingling sensations in the arms and legs, irregular eye movements, appetite loss, nausea, and others. [healthcommunities.com]

  Headaches, chest pain, nausea, and fever are some of the side effects of this drug. [webmd.com]

  Nausea, vomiting, indigestion, headaches, confusion and drowsiness sometimes occur but usually subside in a few weeks. Dosages Recommended By Investigators. Comes in 250 and 500 mg capsules. Dose is primarily based on body weight. [anxieties.com]

• Constipation

  It can also lead to stomach pain, constipation, nausea, and trouble concentrating. Muscle Relaxants Although experts aren't sure why, muscle relaxants can treat a variety of fibromyalgia symptoms. Cyclobenzaprine ( Flexeril ). [webmd.com]

  The most common side effects are constipation, mild nausea or vomiting, and mild dizziness, drowsiness, or lightheadedness. These problems usually go away as the body adjusts to the drug and do not require medical treatment. [science.jrank.org]

  ‘Patients should be warned of possible side effects of this anticonvulsant medication (eg, nausea, vomiting, headache, diplopia, constipation, confusion, ataxia).’ ‘Her eyesight was impaired by glaucoma and she was on anticonvulsant drugs.’ [en.oxforddictionaries.com]

• Abdominal Pain

  Side effects are usually mild or moderate and include the following: Abdominal pain, nausea, vomiting Dizziness Double vision Drowsiness, fatigue Hyponatremia Loss of coordination, abnormal gait Zonisamide (Zonegram)—This drug is approved for use in adults [healthcommunities.com]

  Other general side effects of anticonvulsants that do not usually require medical attention include: mild coordination problems mild dizziness abdominal pain or cramping sinus pain sleeplessness or nightmares change in appetite mild feelings of anxiety [encyclopedia.com]

  These include nausea, abdominal pain, dizziness, sleepiness, irritability, anxiety or mood changes. These are usually not serious, but may worry some people and should be discussed with your doctor or pharmacist. [rch.org.au]

  Side effects for the drug are behavioral disturbances, nausea and drowsiness, hiccups, headache, rash, decrease in appetite, abdominal pain, and an unsteady walk. [dash.harvard.edu]

• Mucocutaneous Rash

  Anticonvulsant hypersensitivity syndrome is a disease characterized by multisystemic involvement, fever, lymphadenopathy, mucocutaneous rash, hypertransaminasemia and peripheral eosinophilia. [ncbi.nlm.nih.gov]

• Seizure

  Individuals whose seizures at the most recent visit were fully controlled (seizure-free) for 6 months or longer were more likely to have ever tried, or currently used, oxcarbazepine or carbamazepine than those with uncontrolled seizures. [ncbi.nlm.nih.gov]

• Nystagmus

  Symptoms seen in anticonvulsant toxicity can include confusion, nystagmus, ataxia lethargy, coma, respiratory depression, and death. [ncbi.nlm.nih.gov]

  Inactivation of Na+ channels Zero-order elimination (i.e., constant rate of drug eliminated) Gingival hyperplasia Stevens-Johnson syndrome Hirsutism Drug-induced lupus erythematosus Osteopathies Megaloblastic anemia Nystagmus, diplopia, ataxia Peripheral [amboss.com]

  Adverse reactions that may occur with the administration of an anticonvulsant drug include the following: • Drowsiness, weakness, dizziness • Headache, somnolence • Nystagmus (constant, involuntary movement of the eyeball) • Ataxia (loss of control of [basicmedicalkey.com]

  Overdoses of gabapentin have produced dizziness and diarrhoea, and those of lamotrigine lethargy, ataxia and nystagmus. [link.springer.com]

[…] or a delayed systemic hypersensitivity reaction after intake of a drug that they had also taken during a previous anticonvulsant DRESS which had occurred months or years earlier; in the fifth, a possible reaction was prevented thanks to the allergy workup [ncbi.nlm.nih.gov]

Initial emergency interventions by the interprofessional team include: Obtaining a thorough history and drug history whenever possible Recognition of toxidromes when present Stabilization including hemodynamic and airway support Laboratory workup including [statpearls.com]

Refer patients with intractable spells to a neurologist or an epileptologist for further workup, including video-electroencephalographic (EEG) monitoring, to characterize the etiology of their seizures. [emedicine.medscape.com]

• Human Herpesvirus 6

  Human herpesvirus 6 (HHV6) antibody titers increased significantly within 15 days. There was a favourable outcome after discontinuation of the drugs and corticosteroid therapy. [ncbi.nlm.nih.gov]

[…] should be avoided if possible → teratogenic effects Newer anticonvulsants: lack of medical data and trials during pregnancy Choice of treatment depends on type of seizure and which substance enables optimal control of treatment. [amboss.com]

Severe neurological and psychomotor deterioration combined with increased seizure activity showed a lack of response to the treatment. At the age of 29 mon the patient was in a pre-comatose stage at which time melatonin was added to treatment. [ncbi.nlm.nih.gov]

Anticonvulsants are also being used in the treatment of neuropathic pain and as mood stabilizers in the treatment of psychiatric disorders such as bipolar disorder. [medlink.com]

As has been the trend with prognosis in sICH, scores have been developed to stratify sICH patients’ risk of seizures. [ahajournals.org]

Prognosis Patients often recover fully from anticonvulsant toxicity. Cardiac and neurologic complications may lead to permanent debilitating conditions if resuscitation is not available. This can cause significant morbidity and mortality. [ncbi.nlm.nih.gov]

Kaplan, The Clinical Features, Diagnosis, and Prognosis of Nonconvulsive Status Epilepticus, The Neurologist, 10.1097/01.nrl.0000162954.76053.d2, 11, 6, (348-361), (2005). [doi.org]

There is some evidence that initiating anticonvulsants after a single seizure may not result in improvement in the long term prognosis and may not reduce the risk of injury or mortality.1,2 Selection of an anticonvulsant is generally guided by the type [bpac.org.nz]

The most common etiologic factors were hypoglycemia (14.6%), hypoxic ischemic encephalopathy (12.2%), and hypocalcemia (12.2%). [go.gale.com]

Investigations ruled out an infectious etiology; an adverse event following phenobarbital administration was considered. [ncbi.nlm.nih.gov]

It is hoped that this will further our understanding of the initial stages of pregnancy and the etiology of various reproductive disorders. [news-medical.net]

Investigators have reported epidemiologic data and described the pathophysiology, diagnostic criteria, and management options. [ncbi.nlm.nih.gov]

Epidemiological and medical aspects of epilepsy in the elderly. Epilepsy Res 2006; 68:Suppl 1:S39-S48. [slideshare.net]

The epidemiology of epilepsy revisited. Curr Opin Neurol, 16 (2003), pp. 165-170 [4] P.M. Preux, M. Druet-Cabanac. Epidemiology and aetiology of epilepsy in sub-Saharan, Africa. Lancet Neurol, 4 (2005), pp. 21-31 [5] T.L. Mac, D.S. Tran, F. Quet, P. [elsevier.es]

Finally, areas for future research and exploring the pathophysiology and use of AEDs in this population are also discussed. © The Author(s) 2015. Published by Oxford University Press on behalf of the Society for Neuro-Oncology. All rights reserved. [ncbi.nlm.nih.gov]

Perhaps the greatest evidence that glutamate modulation might be important in the pathophysiology of mood disorders comes from the clinical use of the anticonvulsant lamotrigine. [dictionary.cambridge.org]

Preventing or arresting seizures. 2. An agent having such action. anticonvulsant A drug used to prevent or reduce the severity of epileptic attacks, or to prevent dangerous muscle contraction in electroconvulsive therapy. [medical-dictionary.thefreedictionary.com]

Treatment with antiepileptic drugs (AEDs) can alleviate spontaneous seizure activity without preventing the progression and development of epileptogenesis. [ncbi.nlm.nih.gov]

Retrieved from https://www.yourdictionary.com/anticonvulsant anticonvulsant noun A drug that prevents or relieves convulsions. [yourdictionary.com]

Anticonvulsant drugs prevent the convulsions typical of epilepsy and other disorders. Anticonvulsant medicines are used to treat epilepsy by controlling convulsions. An anticonvulsant drug is used to prevent or alleviate convulsions. [collinsdictionary.com]