Presentation
The present observation is difficult to explain by the current view on the origin of latent P. malariae infections and recurrences which are thought to arise from intra-erythrocytic development stages susceptible to common antimalarials. [ncbi.nlm.nih.gov]
Malaria - Overview How to Protect Yourself Against Malaria World Malaria Risk Chart Risk is present throughout the country, including urban areas, risk present at all altitudes. Limited risk is present in the city of Antananarivo. [iamat.org]
[…] on admission presenting instead with vomiting and diarrhea. [bioline.org.br]
Presently, he directs a toxicology division within the Drug Development Unit at NUS. He has published more than 40 papers in internationally recognized journals and has won multiple university-level teaching excellence awards. [books.google.de]
Cardiovascular
- Cyanosis
Methemoglobinemia is a complication that may be associated with high-dose regimens of quinine or the derivatives chloroquine and primaquine. [24] A patient presenting with cyanosis and a normal PaO 2 on room air should be suspected of having methemoglobinemia [emedicine.medscape.com]
Liver, Gall & Pancreas
- Liver Dysfunction
Agranulocytosis; aplastic anemia; hypersensitivity reactions like rashes, fixed drug eruptions, erythema multiforme of the Steven Johnson type, exfoliative dermatitis, serum sickness; liver dysfunction; anorexia, vomiting and acute hemolytic anemia can [malariasite.com]
Workup
Rhythm
- Sinus Arrhythmia
Cardiovascular effects have been recorded with bradycardia and sinus arrhythmia being consistently recorded in 68% of patients treated with mefloquine (in one hospital-based study). [en.wikipedia.org]
Less frequently it can cause nightmares, sleeping disturbances, dizziness, ataxia, sinus bradycardia, sinus arrhythmia, postural hypotension, and an ‘acute brain syndrome’ consisting of fatigue, asthenia, seizures and psychosis. [malariasite.com]
Blocks
- First-Degree Atrioventricular Block
Some cardiac changes were reported during a clinical trial, notably non specific ST changes and a first degree atrioventricular block (these disappeared when the patients recovered from the malarial fever). [en.wikipedia.org]
Treatment
Drug resistance may lead to treatment failure, but treatment failure is not necessarily caused by drug resistance despite assisting with its development. [en.wikipedia.org]
Oral artemisinin-based combination treatments now form the basis of antimalarial treatment policies in most malaria endemic countries. [eurekalert.org]
Although ACT has become the official first-line treatment for uncomplicated malaria in Burkina Faso since 2005, malaria control in the study area continues to be mainly based on home treatment with CQ [18], [40]. [dx.doi.org]
Prognosis
[…] diagnosis of cutaneous lupus erythematosus / FlorianWeber, Peter Fritsch ; Photosensitivity in lupus erythematosus / Percy Lehmann, Annegret Kuhn ; Relationship between cutaneous and systemic lupus erythematosus / Christof Specker, Matthias Schneider ; Prognosis [worldcat.org]
Little Annabelle Potts needs your help The devastating prognosis of DIPG has sent some Australian parents to Mexico, paying up to $300,000 a year for an unproven therapy in the hope to save their children, as reported in The Sunday Telegraph last week [dailytelegraph.com.au]
What Is the Prognosis for Malaria? If promptly diagnosed and treated, malaria is usually not fatal. Long-term effects are uncommon with prompt treatment. [emedicinehealth.com]
Etiology
Similar to proposed etiologies for SLE, current theories discuss a multifactorial relationship leading to the development of cutaneous lupus including genetic susceptibility, autoimmune induction, and immune system damage. B. [ncbi.nlm.nih.gov]
Epidemiology
[…] open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of infectious and sexually transmitted diseases in humans, as well as related molecular genetics, pathophysiology, and epidemiology [eurekalert.org]
The life‐history timings used in Figures 1 and 2 are arbitrary and will vary according to local epidemiology, particularly prevailing levels of human immunity. [onlinelibrary.wiley.com]
Recent remarkable molecular epidemiological studies in South America, southern Africa, and Southeast Asia have challenged this view. [doi.org]
The epidemiology of malaria with special emphasis on transmission, morbidity, mortality and disease control in Ghana. Legon, Ghana, Noguchi Memorial Institute for Medical Research, 1995 (unpublished research report). 8. Ahmed K. [scielosp.org]
Pathophysiology
Infectious Diseases is an open access journal publishing original peer-reviewed research articles in all aspects of the prevention, diagnosis and management of infectious and sexually transmitted diseases in humans, as well as related molecular genetics, pathophysiology [eurekalert.org]
The pathophysiology of vivax malaria. Trends Parasitol, 2009, 25, 220–227 [ PubMed ] [ Google Scholar ] Atteke C., Ndong J.M., Aubouy A., Maciejewski L., Brocard J., Lebibi J. & Deloron P. [ncbi.nlm.nih.gov]
Prevention
There are two general approaches to preventing the spread of resistance: preventing malaria infections, and preventing the transmission of resistant parasites. [en.wikipedia.org]
Intermittent preventive treatment for the prevention of malaria during pregnancy in high transmission areas. Malar J. 2007 Dec 4. 6:160. [Medline]. [Full Text]. Trape JF, Tall A, Diagne N, et al. [emedicine.medscape.com]
Travelers to these areas need to protect themselves from malaria by preventing mosquito bites and taking medication to prevent malaria infection. [travelreadymd.com]
I would have just gone and been really nervous, but this helped reassure me that I was taking precautions to prevent medical issues. I ended up getting pills for malaria prevention and typhoid and some antibiotics for travelers’ stomach.” [passporthealthusa.com]
Antimalarial medicine for prevention If you are travelling to an area with a risk of malaria, your doctor will recommend you take antimalarial tablets to prevent you from becoming infected. [hse.ie]