Presentation
In S cells, a novel iron-binding intermediate (band D) was identified that was not present in R cells and may be a "sensitivity factor" to gallium. [ncbi.nlm.nih.gov]
In S cells, a novel iron-binding intermediate (band D) was identified that was not present in R cells and may be a “sensitivity factor” to gallium. [jpet.aspetjournals.org]
Presented at the American Society of Hematology 41st Annual Meeting. New Orleans, LA December 3–7, 1999. (abstract 2685). Google Scholar 41. [link.springer.com]
Entire Body System
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Fatigue
Fatigue Fatigue is very common, and can be due to the cancer itself or the chemotherapy. Other potential contributing factors include anemia, insomnia, depression and other medications, such as pain medications. [livestrong.com]
See All 2 Answers 2 Answers A Side effects of Eloxatin (oxaliplatin) may include: nausea or vomiting; constipation; diarrhea; loss of appetite; muscle or back pain; swelling at the site of the injection; change in taste; dizziness; fatigue; hair loss; [sharecare.com]
Additional side effects include fatigue, headaches, water retention etc. Prolonged and repeated administration of antineoplastic agents may have permanent negative effects on vital organs such as heart, kidneys, lungs or liver. [ic.steadyhealth.com]
Other side effects of these drugs are, fatigue, headaches, and water retention. The long-term use of these drugs can damage some vital organs, like the heart, kidneys, liver, and the lungs. [buzzle.com]
Some of the general adverse reactions after this drug is taken could be fatigue and headache. The level of these two can vary from patient to patient depending on the immune system. [castorlifecare.com]
Respiratoric
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Nasal Congestion
This is a clinical case report of a 45-year-old nurse who developed throat irritation and chronic nasal congestion followed by sinusitis shortly after beginning work at an oncological out-patient clinic. [ncbi.nlm.nih.gov]
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Throat Irritation
This is a clinical case report of a 45-year-old nurse who developed throat irritation and chronic nasal congestion followed by sinusitis shortly after beginning work at an oncological out-patient clinic. [ncbi.nlm.nih.gov]
Gastrointestinal
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Nausea
As control of vomiting has improved, attention has shifted to control of nausea, a related but distinct and equally important problem. Additional efforts will be necessary to understand mechanisms of nausea and to identify optimal remedies. [ncbi.nlm.nih.gov]
Toxicity includes immunosuppression with increased risk of infection and nausea and vomiting. [quizlet.com]
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Abdominal Pain
Call your doctor or midwife if you have any of these side effects: Vaginal bleeding or spotting Nausea Fatigue or lightheadedness Cramping abdominal pain 1 Answer A Potential benefits of methotrexate for ectopic pregnancy include the following: Can end [sharecare.com]
Side effects include nausea, vomiting, diarrhea, abdominal pain, stomatitis, edema, paresthesias, and hyperbilirubinemia. Often the hands and feet become dry and painful. [quizlet.com]
pain Cyclophosphamide Hemorrhagic cystitis Vincristine Neurotoxicity Irinotecan Diarrhea (early and late), nausea and vomiting, cholinergic syndrome, myelosuppression Cytarabine Cerebral damage Nearly all antineoplastic drugs have side effects that patients [doctorlib.info]
Eyes
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Dry Eyes
These included epiphora(17 cases), eye discharge(10 cases), conjunctivitis(6cases ), blurred vision(3 cases), and eye discomfort(2 cases), as well as eye pain, pruritus, dry eye, hordeolum, and visual loss(1 case each). [ncbi.nlm.nih.gov]
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Eye Pain
These included epiphora(17 cases), eye discharge(10 cases), conjunctivitis(6cases ), blurred vision(3 cases), and eye discomfort(2 cases), as well as eye pain, pruritus, dry eye, hordeolum, and visual loss(1 case each). [ncbi.nlm.nih.gov]
Skin
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Alopecia
Frequently occurring adverse effects of amsacrine include leukopenia and thrombocytopenia in patients with solid tumors; nausea, vomiting, and diarrhea; mucositis in patients receiving higher doses (leukemia patients); alopecia; hepatotoxicity; and phlebitis [ncbi.nlm.nih.gov]
Fever, rash, cellulitis, pain at the injection site, sore throat, conjunctivitis, and alopecia also occur frequently. [quizlet.com]
Treatment
Malignant melanoma cells are particularly well known for their unresponsiveness to chemotherapy; only about 30% of tumors exhibit a transient clinical response to treatment. [ncbi.nlm.nih.gov]
Prognosis
BACKGROUND: Although patients with neuroendocrine tumors typically exhibit an indolent clinical course, the pace of disease accelerates and the prognosis deteriorates once objective progression of disease begins. [ncbi.nlm.nih.gov]
Hence, the need to take into consideration the prognosis of the disease in assessing the extent of benefit is another sensible distinction to be made. [esmoopen.bmj.com]
As overt HF induced by chemotherapy has such a worse prognosis, there is a stringent need to improve our ability to detect CTRCD at a subclinical level. [romanianjournalcardiology.ro]
Regulatory T cells and CD20 B cells in pediatric very severe aplastic anemia: possible clinical markers for evaluating the therapeutic efficacy and prognosis. Hematology. 2018 Jul 11. 1-5. [Medline]. Brodsky RA. Acquired Aplastic Anemia. [medscape.com]
Etiology
The Drug Etiology of Agranulocytosis and Aplastic Anemia. New York: Oxford University Press; 1991. Issaragrisil S, Sriratanasatavorn C, Piankijagum A, Vannasaeng S, Porapakkham Y, Leaverton PE, et al. Incidence of aplastic anemia in Bangkok. [medscape.com]
Integrative Analysis of Lung Cancer Etiology and Risk (INTEGRAL) Consortium for Early Detection of Lung Cancer., Guida F, Sun N, Bantis LE, et al. Assessment of Lung Cancer Risk on the Basis of a Biomarker Panel of Circulating Proteins. [emedicine.medscape.com]
The most recognized clinical pattern consists of self-limiting dyspnea of uncertain etiology, in some cases involving bronchoconstriction [ 5 – 8 ]. [annonc.oxfordjournals.org]
Epidemiology
Surveillance Epidemiology and End Results (SEER) stat fact sheets. . Accessed March 15, 2010. [ajpb.com]
Surveillance, Epidemiology, and End Results Program. Available at . Accessed: April 12, 2019. Jonnalagadda S, Smith C, Mhango G, Wisnivesky JP. [emedicine.medscape.com]
Surveillance, Epidemiology, and End Results Program. SEER Stat Fact Sheets: Testis Cancer. National Cancer Institute. Available at . Accessed: September 5, 2019. American Cancer Society. Cancer Facts & Figures 2019. Available at . [medscape.com]
Since the 1970s, epidemiological studies conducted with nurses handling AD have shown an increase in risk of cancers5 6 such as leukemias5 and/or reprotoxic effects. [bmjopen.bmj.com]
Yancik R: Cancer burden in the aged: An epidemiologic and demographic overview. Cancer 80:1273-1283, 1997. 3. Barry P, Katz PR: On cancer screening in the elderly (editorial). J Am Geriatr Soc 37:913-914, 1989. 4. [cancernetwork.com]
Pathophysiology
Pathophysiology, diagnosis, and treatment of paroxysmal nocturnal hemoglobinuria: a review. Eur J Haematol. 2015 Sep. 95 (3):190-8. [Medline]. Brodsky RA, Mukhina GL, Li S, Nelson KL, Chiurazzi PL, Buckley JT, et al. [medscape.com]
Cardiotoxicity associated with cancer therapy: Pathophysiology and prevention. Rev Port Cardiol. 2013;32(5):395-409 22. Florescu M, Cinteza M, Vinereanu D. Chemotherapy-induced Cardiotoxicity. [romanianjournalcardiology.ro]
A delayed-type hypersensitivity reaction involving immunological and non-immunological mechanisms has been proposed as a possible pathophysiological mechanism [ 45 ]. [annonc.oxfordjournals.org]
Long-term cardiovascular toxicity in children, adolescents, and young adults who receive cancer therapy: pathophysiology, course, monitoring, management, prevention, and research directions a scientific statement from the american heart association. [revistas.uis.edu.co]
Prevention
[…] that are used to treat various cancers Associated cancers: Cancers of the breast, lung, ovary, liver, and bladder; cancers of the hematopoietic system Most important routes of exposure: Inhalation, skin contact, ingestion, needle stick injury Uses: Prevent [carexcanada.ca]
Inhibiting or preventing the growth or development of malignant cells. an′ti·ne′o·plas′tic n. antineoplastic [-nē′ōplas′tik] Etymology: Gk, anti neos, new, plasma, something formed 1 pertaining to a substance, procedure, or measure that prevents the proliferation [medical-dictionary.thefreedictionary.com]
Moreover, the ability of Bryo-1 to trigger RANTES and MIP1-α suggests that Bryo-1 could potentially be used to prevent HIV-1 infection. Finally, induction of a Th2 response by Bryo-1 may help treat inflammatory diseases mediated by Th1 cells. [ncbi.nlm.nih.gov]
Centers for Disease Control and Prevention. National Institute for Occupational Safety and Health. NIOSH Alert: Preventing Occupational Exposures to Antineoplastic and Other Hazardous Drugs in Health Care Settings. . Accessed March 21, 2017. 3. [oncnursingnews.com]