Presentation
Image Collections Hundreds of image-rich slideshow presentations visually engage and challenge readers while expanding their knowledge of both common and uncommon diseases, case presentations, and current controversies in medicine. [reference.medscape.com]
[…] live in institutions immigrants from Latin america, southeast asia, Africa Mantoux Test ( PPD) Multiple puncture test (Tine) Given ID in the forearm (read results in 48-72 hrs 10 mm or greater induration=positive reaction. ( doesn't mean disease is present [quizlet.com]
Therefore in the present investigation, we studied the synergistic effect of some plant extracts/phytochemicals along with the Isoniazid and rifampicin. The M. tuberculosis H37Ra was used as model organism. [omicsonline.org]
Patients without HIV infection typically present with chronic, nontender lymphadenopathy. 15, 17 Patients with HIV infection usually present with fever, night sweats, and weight loss. 5, 18 The nodes are discrete, firm, and nontender; with time, a firm [aafp.org]
The student will also take part in the University Graduate School and Faculty Doctoral Research Development Programme (DRDP) including transferable skills (eg presentation skills, scientific writing and employability skills) which aid in their future [westminster.ac.uk]
Entire Body System
- Fatigue
Patient Monitoring INH Prophylaxis Seen Q month & assess for s/s of liver damage or other toxic effects, anorexia, n/v, fatigue, weakness, paresthesias of hands/feet, persistent dark urine, icterus, rash, elevated temp Routine LFTs (Q mo) for patients [slideshare.net]
Clinical signs of liver toxicity can include nausea, vomiting, fatigue, abdominal pain and loss of appetite. [livestrong.com]
[…] right away if you have any of the following symptoms: Fever for 3 or more days Pain in the lower abdomen Itchiness or a rash Nausea, vomiting, or no appetite Yellowish skin or eyes Dark or brown urine Tingling, burning, or numbness of the hands and feet Fatigue [webmd.com]
CNS: Fatigue, drowsiness, headache, ataxia, confusion, dizziness, inability to concentrate, generalized numbness, pain in extremities, muscular weakness. Special Senses: Visual disturbances, transient low-frequency hearing loss, conjunctivitis. [robholland.com]
Must monitor hepatic function (e.g.,serum aspartate aminotransferase) at least once per month, especially if signs of hepatitis (anorexia, malaise, fatigue, nausea, and jaundice). May result from metabolite, acetylhydrazine. [cyto.purdue.edu]
Gastrointestinal
- Nausea
Common adverse events in clinical trials included nausea, arthralgia, and headache. Serious adverse events included elevated serum transaminase levels and rate-corrected QT-interval prolongation. [ncbi.nlm.nih.gov]
Peripheral neuropathy and CNS toxicity Causes vitamin B6 (pyridoxine) deficiency Causes decreased GABA synthesis Drug-induced hepatitis Most frequent major toxic effect, potentially fatal -> loss of appetite, nausea, vomiting, jaundice increased ALT [quizlet.com]
Most common are rash (0.8%), fever (0.5%), and nausea and vomiting (1.5%). (GG8th90). Jaundice Most notable problem and has resulted in death. [cyto.purdue.edu]
Thioacetazone may cause nausea, vomiting, diarrhoea and skin rashes. Cases of thrombocytopenia and aplastic anaemia are also recorded. Thioridazine- a study to know the effectiveness of Thioridazine treatment was carried out. [onlymyhealth.com]
Clinical signs of liver toxicity can include nausea, vomiting, fatigue, abdominal pain and loss of appetite. [livestrong.com]
- Abdominal Pain
Clinical signs of liver toxicity can include nausea, vomiting, fatigue, abdominal pain and loss of appetite. [livestrong.com]
May be worsened by isoniazid and pyridoxine. · Other effects that have been observed -- pruritus, joint pain, gastrointestinal upset, abdominal pain, malaise, headache, dizziness, mental confusion, disorientation, and possible hallucination. [cyto.purdue.edu]
Ethambutol HCl Adverse Effects Fever, malaise, dizziness, headache Dermatitis, pruritis Thrombocytopenia Common: N/V, anorexia, abdominal pain SEVERE: Optic neuritis, loss of acuity, loss of red-green discrimination Drug Interactions Aluminum salts may [slideshare.net]
Minor adverse effects include nausea, vomiting, epigastric pain, abdominal pain, arthralgia, arthritis, peripheral neuropathy, cutaneous pruritus, headache, and changes in behavior (insomnia, anxiety, decreased libido, and euphoria). [scielo.br]
Treatment
In most susceptible cases, the patient undergoes 6 months of treatment. Treatment lasts for 9 months if the patient's sputum culture result is still positive after 2 months of therapy. [emedicine.medscape.com]
Bedaquiline is a novel agent with a unique mechanism of action and has the potential to meet a great need in patients with MDR TB who have no other treatment options. [ncbi.nlm.nih.gov]
Treatment Categories have not been used by WHO since 2010. There is more about Treatment Categories. [tbfacts.org]
The participants were patients treated with Directly Observed Treatment (DOT) with treatment schemes I and II (I: indicated for never-treated patients; and II: indicated for relapses and those who had previously discontinued treatment, then returned). [archbronconeumol.org]
Indications for drug therapy Prevention & treatment of tuberculosis No prototype – each drug differs from the others TB: Highly contagious Reportable disease Treatment initiated by specialist Refer for initial work-up & treatment PCP ROLE: Follow patient [slideshare.net]
Prognosis
Abstract Effective antituberculosis drugs have radically improved the prognosis of the patient with active tuberculosis. Surgical therapy is rarely needed, and sanatoria have largely vanished. [ncbi.nlm.nih.gov]
Single-center experience with drug-induced liver injury from India: causes, outcome, prognosis, and predictors of mortality. Am J Gastroenterol. 2010;105:2396–404. [tropicalgastro.com]
Patients with cholestatic hepatitis have a better prognosis. Acute cellular necrosis is indistinguishable from viral hepatitis, which is why extremely high aminotransferase levels can be found. [scielo.br]
Etiology
Competing etiologies particularly acute viral hepatitis may need to be excluded. Risk factors for TB DILI Interactions between genetic, host and environmental factors contribute towards the development of TB DILI. [tropicalgastro.com]
Epidemiology
Faire une suggestion Affiner la recherche Etendre la recherche sur niveau(x) vers le bas Article : Fascicule Article : Fascicule Article : Fascicule Article : Fascicule Article : Fascicule Article : Fascicule Article : Fascicule Article : Fascicule Epidemiology [documentation.ehesp.fr]
The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and [ingentaconnect.com]
References [1] WHO Global tuberculosis control: epidemiology, strategy, financing: WHO report 2011 [2] World Health Organization Global tuberculosis control. [archbronconeumol.org]
Europe and United States: epidemiology, surveillance, and control. Clin Chest Med. 2009;30(4):637-65, vii. [ Links ] 59. Saukkonen JJ, Cohn DL, Jasmer RM, Schenker S, Jereb JA, Nolan CM, et al. [scielo.br]
Miliary tuberculosis: epidemiology, clinical manifestations, diagnosis, and outcome. Rev Infect Dis. 1990;12:583–90. 41. Trautner BW, Darouiche RO. Tuberculous pericarditis: optimal diagnosis and management. Clin Infect Dis. 2001;33:954–61. 42. [aafp.org]
Pathophysiology
The latest recommendations include the new MyPlate guide, the Dietary Guidelines for Americans 2010, new and expanded chapters, and a large variety of tables, boxes, and pathophysiology algorithms, all providing need-to-know information with ease. [books.google.com]
Prevention
Encyclopedia Definition 1 Any agent that is active against Mycobacterium tuberculosis and can be used in the treatment of or in the prevention of tuberculosis. [tititudorancea.com]
Centers for Disease Control and Prevention (CDC) (2002 August 13, Reviewed). Frequently Asked Questions, Questions and Answers about TB. National Center for HIV, STD and TB Prevention Division of Tuberculosis Elimination [On-line information]. [labtestsonline.it]
Preventing or treating tuberculosis. 2. An agent used to prevent or treat tuberculosis. Synonym: antituberculotic [medical-dictionary.thefreedictionary.com]
Allium cepa (onion) possesses antibiotic activity against both Gram-positive and Gram-negative bacteria and can be used to prevent tuberculosis most effectively. [globaljournals.org]
We also establish the causality, severity and preventability of the suspected ADR. [ispub.com]