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Anton Syndrome

Presentation

The defect becomes apparent when patients are found describing people or surroundings that are not present, or walking into objects, though the patient will continue to deny that they cannot see even when presented with evidence otherwise. [eyewiki.aao.org]

Outline the typical presentation of a patient with Anton syndrome. Review the risk factors for developing Anton syndrome. [ncbi.nlm.nih.gov]

The aim of this study is to present our experience in clinical presentation, diagnosis and complications of patients with OHVIRA syndrome in a 20-year period. [read.qxmd.com]

Mr B presented to the emergency department because of frequent falls and an inability to grasp anything in front of him. He could recognise his family by their voices but not by sight. [sbs.com.au]

Treatment

/ Management Treatment of ABS is based on the etiology. [ncbi.nlm.nih.gov]

[…] on the treatment of the assumed causative factor of occipital lobe damage. [eyewiki.aao.org]

Delay in diagnosis and treatment can produce serious complications in patient's life and fertility. [read.qxmd.com]

General anesthesia treatment of propriospinal myoclonus in a patient with fibrodysplasia ossificans progressiva. Char, D. S., Hutchison, H. T., Kitterman, J. A., & Gregory, G. A. (2014). [stanfordhealthcare.org]

But, says one man living with the disease, there is a way to save sight: catch it early and allow genetic therapy research enough time to create better treatment options. [sbs.com.au]

Prognosis

Cortical blindness: etiology, diagnosis, and prognosis. Ann Neurol. 1987 Feb;21(2):149-58. [PubMed: 3827223] 7. Trifiletti RR, Syed EH, Hayes-Rosen C, Parano E, Pavone P. Anton-Babinski syndrome in a child with early-stage adrenoleukodystrophy. [ncbi.nlm.nih.gov]

[…] as result of bilateral occipital cortical infarction, the prognosis is poor and patients are unlikely to ever fully recover.[1] References ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Maddula M, Lutton S, Keegan B. [eyewiki.aao.org]

Etiology

The outcome of cortical blindness depends on the age of the patient, etiology, severity, duration, initial recovery time, medical history. [ncbi.nlm.nih.gov]

Though the literature is extremely limited, this syndrome has also been reported in younger age groups when etiology is non-vascular. [eyewiki.aao.org]

Epidemiology

Progressive multifocal leukoencephalopathy, in the setting of human immunodeficiency virus infection Multiple sclerosis Posterior reversible encephalopathy syndrome (PRES) secondary to SARS-CoV-2 (COVID-19) pneumonia Fat embolism syndrome Trousseau syndrome Epidemiology [ncbi.nlm.nih.gov]

Epidemiology Anton Syndrome is most commonly secondary to cerebrovascular accident, so is primarily seen in elderly individuals with multiple vascular risk factors. [eyewiki.aao.org]

Pathophysiology

Pathophysiology of blindness: The ability to recognize visually presented objects depends on the integrity of the following: 1. [ncbi.nlm.nih.gov]

General Pathology/Pathophysiology The exact pathophysiology of Anton Syndrome is unknown. [eyewiki.aao.org]

Prevention

There is no specific primary prevention for Anton Syndrome. [eyewiki.aao.org]

Management in these circumstances should accordingly focus on secondary prevention and rehabilitation. [ncbi.nlm.nih.gov]

Preventive Genomic Sequencing and Care of the Individual Patient. Char, D. (2015). Preventive Genomic Sequencing and Care of the Individual Patient. American Journal of Bioethics, 15(7), 32–33. [stanfordhealthcare.org]

It is related to several conditions in which the physical therapy could take action-preventing co-morbidities. [read.qxmd.com]

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