Thoracic aortic aneurysms can be found incidentally, however, patients can also present with acute dissection and or rupture that can be fatal. Symptoms that might indicate dissection include chest and back pain as well as lightheadedness. [ncbi.nlm.nih.gov]

Patients have increased risk of presenting life threatening aortic rupture. The documents contained in this web site are presented for information purposes only. [orpha.net]

CD-68, a macrophage marker that is normally absent in aorta tissue, is weakly present in the adventitia of thoracic aorta (arrow, K) and strongly present in the media and adventitia of abdominal aorta (arrows, L). [pediatrics.aappublications.org]

• Dyspnea with Sudden Onset

  On presentation, these family members complained of dyspnea and sudden onset of severe pain in the chest, abdomen, or upper and lower extremities (Table 1). [ojrd.biomedcentral.com]

• Non-Cardiac Chest Pain

  Spiral CT in acute non-cardiac chest pain. Clin Radiol 1999; 5438–45. 12. Yamaguchi T, Kuroki K, Ohyama Y, Ishikawa T. Pitfalls of CT diagnosis of aortic dissection: nonvisualized intimal flap in the ascending aorta or aortic arch. [journals.lww.com]

• Left Ventricular Dysfunction

  One advantage of MRA over CTA is the ability to evaluate complications such as hemopericardium, left ventricular dysfunction, and valve regurgitation. [journals.lww.com]

• Short Arm

  When blood is pumped out by the heart, it first travels through the ascending thoracic aorta (up the short arm of the candy cane), then down the descending thoracic aorta (first part of the long arm) into the abdominal aorta (the bottom of the candy cane [tadcoalition.org]

• Bilateral Arm Weakness

  Our investigation revealed that both patients (VII-26 and VII-27) had complained of bilateral arm weakness, effort-induced shoulder pain, and general fatigue. [ojrd.biomedcentral.com]

A good patient history and physical examination are essential, along with imaging studies, electrocardiography, and laboratory studies (see Workup ). Acute aortic dissection can be treated surgically or medically. [emedicine.medscape.com]

PARTICIPANTS: 360 088 treatment episodes of fluoroquinolone use (78%ciprofloxacin) and propensity score matched comparator episodes of amoxicillin use (n=360 088). [ncbi.nlm.nih.gov]

Treatment for an Aortic Aneurysm Surgical or interventional treatment of an aortic aneurysm or dissection will depend on the location and size of the aneurysm. [helios-gesundheit.de]

One study1 reported a rate of aortic aneurysm or dissection of 1.2 cases per 1000 person-years among fluoroquinolone treatment episodes versus 0.7 cases per 1000 person-years among amoxicillin treatment episodes, corresponding to an estimated absolute [gov.uk]

CT scanning may be used to confirm the diagnosis but is less helpful in complications and prognosis. [patient.info]

Obstruction of branch vessels · DX o MRI if available is usually best for imaging ascending aorta o Contrast-enhanced CT can image arch and descending aorta o Transesophageal ultrasound, if available, especially for root and ascending aorta o Angiography · Prognosis [learningradiology.com]

Despite the phenotypic overlap of these syndromes, important differences in prognosis underline the importance of accurate diagnosis to optimize management strategies. [acc.org]

Prognosis is usually good if the AAA is found before it ruptures. Focusing on heart health can prevent an AAA. This means watching what you eat, exercising, and avoiding other cardiovascular risk factors such as smoking. [healthline.com]

BACKGROUND: Hereditary factors play an important etiologic role in thoracic aortic aneurysm and dissection (TAAD), with a number of genes proven to predispose to this condition. [ncbi.nlm.nih.gov]

Atherosclerosis is important for the etiology of descending aortic aneurysm and its histological features are similar to that of abdominal aortic aneurysm. Cystic medial necrosis is also important for the etiology of aortic dissection. [ci.nii.ac.jp]

The University of Michigan is home to the International Registry of Aortic Dissection, and several research laboratories that are exploring the molecular etiologies of aortic diseases. [umcvc.org]

Both twins had deep vein thrombosis of unclear etiology, possibly attributed entirely to immobility after surgery. [pediatrics.aappublications.org]

Aortopathies: etiologies, genetics, differential diagnosis, prognosis and management. Am J Med 2013;126:670-8. Elefteriades JA, Farkas EA. Thoracic aortic aneurysm clinically pertinent controversies and uncertainties. [acc.org]

The results presented confer light to the importance of mortality statistics and the need for epidemiologic studies to understand unique trends in our own population. [ncbi.nlm.nih.gov]

Data from epidemiologic and non-clinical studies indicate an increased risk of aortic aneurysm and dissection after intake of fluoroquinolones. [gov.uk]

In Brazil, epidemiologic studies on aneurysms are scarce and the available literature is outdated. [bmcpublichealth.biomedcentral.com]

Rheumatology (10) Microbiology (10) Health Care Sciences (9) Anaesthesiology and Intensive Care Medicine (9) Histology, Embryology (8) Pharmacology (8) Radiology and Imaging (7) Biophysics (6) Diabetology, Dietetics (4) Immunology, Allergology (4) Epidemiology [portal.mefanet.cz]

Genetic studies of human patients and murine models have yielded invaluable insights into the pathophysiology of aneurysm formation and progression in MFS. [ncbi.nlm.nih.gov]

Department of Pathophysiological and Experimental Pathology, Graduate School of Medical Sciences Kyushu University Higashi-ku, Fukuoka Japan [link.springer.com]

Internal Medicine (100) Oncology, Radiation Therapy (68) Paediatrics, Neonatology (64) Neurology (49) Gastroenterology and Hepatology (47) Cardiology, Angiology (44) Neurosurgery (36) Obstetrics, Gynaecology (26) Otorhinolaryngology (26) Physiology and Pathophysiology [portal.mefanet.cz]

Aortic dissection: epidemiology, pathophysiology, clinical presentation, and medical and surgical management. In: Sidawy AN, Perler BA, eds. Rutherford's Vascular Surgery and Endovascular Therapy. 9th ed. Philadelphia, PA: Elsevier; 2019:chap 81. [medlineplus.gov]

Animal studies aimed to clarify the pathophysiological mechanism of this association would also be valuable. Results of our study should be interpreted in light of both its strengths and limitations. [jamanetwork.com]

These poor outcomes are preventable by surgical repair; however, identifying at-risk individuals is difficult. [ncbi.nlm.nih.gov]