Presentation
Conclusions Male patients with BAV present more frequently with ≥moderate AR at first presentation whereas female present more frequently with ≥moderate AS. Furthermore, diffuse dilatation of the aorta was more prevalent in male. [onlinejacc.org]
Cystic medial necrosis present in the aneurysmal wall probably arose as a consequence of poststenotic dilatation. [jhu.pure.elsevier.com]
Presented at: American College of Cardiology Scientific Session; March 17-19, 2017; Washington, D.C. Yoon SH, et al. J Am Coll Cardiol. 2017;doi:10.1016/j.jacc.2017.03.017. Disclosure: Yoon reports no relevant financial disclosures. [healio.com]
Failure to present until clinical symptoms develop—either because the murmur is not detected or is lost to follow-up—can have important consequences. [bmj.com]
Entire Body System
- Coarctation of the Aorta
THIS IS CASE 4,555 OF 4,932 JUMP TO CASE 4,554 Coarctation of the Aorta with Dilated Left Subclavian Artery 4,553 Type A Dissection Nicely Seen with Gated Acquisition CURRENT CASE Bicuspid valve with Extensive Calcification and Aortic Stenosis 4,556 Pericardial [ctisus.com]
The bicuspid aortic valve is associated with abnormalities of the aortic wall such as coarctation of the aorta, aortic dissection, and aortic aneurysm. Most patients with a bicuspid aortic valve will develop some complication during life. [ncbi.nlm.nih.gov]
This arrangement is much more common in patients with coarctation of the aorta, whose valves function adequately. [emedicine.medscape.com]
Coarctation of the aorta signifies a constriction of the aorta in the region of its juncture with the ductus arteriosus or its vestige. The term, congenital stenosis of the isthmus, is also employed. [jamanetwork.com]
Other associated lesions include VSD, coarctation of the aorta, and the Shone complex (coarctation of the aorta, parachute mitral valve, supravalvular mitral ring, sub-AS). [ecrjournal.com]
Cardiovascular
- Heart Disease
Session Title: Valvular Heart Disease: AV - Bicuspid/Gender; Low Gradient/Preserved EF Abstract Category: 40. Valvular Heart Disease: Clinical Presentation Number: 1193M-01 2016 American College of Cardiology Foundation [onlinejacc.org]
Disease 502 The Heart and Pregnancy 537 Chapter32 Women and Heart Disease 553 The Elderly and Aging 561 Chapter34 EndofLife Care 587 The Heart and Other Organ Systems 595 Chapter 35B Hematologic Disorders and the Heart 604 Chapter35C The Heart and the [books.google.com]
The Cardiology section is involved in treating patients with disorders of the heart and vascular tree including coronary artery disease, congestive heart failure, valve disease, congenital heart defects, cardiomyopathy and peripheral vascular disease. [hopkinsmedicine.org]
[…] defect (Medical Encyclopedia) [ Read More ] Heart Valve Diseases Also called: Valvular heart disease Your heart has four valves. [icdlist.com]
Further Reading All Congenital Heart Disease Content Congenital heart disease and exercise Cyanotic Congenital Heart Diseas Causes and Symptoms of Hypoplastic Left Heart Syndrome Double Inlet Left Ventricle (DILV) Last Updated: Feb 26, 2019 Written by [news-medical.net]
- Heart Murmur
Get your heart murmur checked People with heart murmurs are at an increased risk of an aortic valve disease called bicuspid aortic valve disease. [pennmedicine.org]
A heart murmur was noted during that consultation but not followed up. He later recalled that as a child he underwent annual review for a heart murmur. At age 16 he was reassured and discharged from clinic. [bmj.com]
The main sign of heart valve disease is an unusual heartbeat sound called a heart murmur. Your doctor can hear a heart murmur with a stethoscope. But many people have heart murmurs without having a problem. [icdlist.com]
Both ways cause the heart to work harder which may lead to heart failure later in life. The symptoms of failing valves include difficulty in breathing, chest pain, fainting (syncope), heart murmur and fatigue. [singhealth.com.sg]
- Systolic Murmur
An attenuation of systolic murmur also occurred. No aortic diastolic murmur was detected. [jpgmonline.com]
3/6 or louder systolic murmur. [aafp.org]
On clinical examination the patient had severe aortic stenosis with a slow rising pulse, narrow pulse pressure, and an ejection systolic murmur radiating to the carotids. … View Full Text Log in Log in using your username and password Log in through your [bmj.com]
On clinical examination the patient had severe aortic stenosis with a slow rising pulse, narrow pulse pressure, and an ejection systolic murmur radiating to the carotids. He had left ventricular failure. [ncbi.nlm.nih.gov]
Physical exam reveals a systolic crescendo-decrescendo murmur, heard best at the heart base and radiates to the carotids. He is sent for further evaluation with an echocardiogram. [medbullets.com]
- Pulsus Parvus et Tardus
parvus et tardus weak pulses with a delayed peak Imaging Radiography indication for all patients findings cardiomegaly calcification pulmonary congestion Echocardiography indications for all patients diagnostic test views transthoracic echocardiogram [medbullets.com]
Signs Examination of the pulse in significant AS reveals a slow-rising, flat character called pulsus parvus et tardus. [ 7 ] Blood pressure will show a narrow pulse pressure (difference between systolic and diastolic pressures). [patient.info]
The phenomenon known as pulsus parvus et tardus refers to a weak (parvus) and delayed (tardus) carotid upstroke. To asses for parvus, it is often helpful to palpate one’s own carotid artery while concurrently palpating the patient’s carotid artery. [healio.com]
A pulsus parvus et tardus (the arterial pulse is slow to increase and has a reduced peak) can be appreciated by palpating the carotid pulse of patients with severe aortic stenosis. [textbookofcardiology.org]
- Narrow Pulse Pressure
On clinical examination the patient had severe aortic stenosis with a slow rising pulse, narrow pulse pressure, and an ejection systolic murmur radiating to the carotids. … View Full Text Log in Log in using your username and password Log in through your [bmj.com]
On clinical examination the patient had severe aortic stenosis with a slow rising pulse, narrow pulse pressure, and an ejection systolic murmur radiating to the carotids. He had left ventricular failure. [ncbi.nlm.nih.gov]
Signs Examination of the pulse in significant AS reveals a slow-rising, flat character called pulsus parvus et tardus. [ 7 ] Blood pressure will show a narrow pulse pressure (difference between systolic and diastolic pressures). [patient.info]
Neurologic
- Stroke
TAV: 2.5%, p = 0.82) but a higher rate of stroke (BAV: 2.4 vs TAV: 1.6%, p = 0.02) among bicuspid patients. With CMS-linkage, the combined endpoint of death and stroke were similar at 1-year (BAV: 12.9 vs. TAV: 14.1%, p = 0.75). [acc.org]
Skip to main content Search American Heart Association Search" Heart Attack And Stroke Symptoms Volunteer Donate Now Find Your Local Office Healthy Living Healthy Living Healthy Eating Healthy Lifestyle Fitness Pets and Your Health / Healthy Bond for [heart.org]
[ Time Frame: 1 month ] Stroke [ Time Frame: 6 months ] Stroke [ Time Frame: 1 year ] Stroke [ Time Frame: 2 years ] Stroke [ Time Frame: 3 years ] Stroke [ Time Frame: 4 years ] Stroke [ Time Frame: 5 years ] Myocardial infarction [ Time Frame: 1 month [clinicaltrials.gov]
Weak pulse in one arm or thigh compared with the other Leg pain Difficulty walking Leg paralysis When to see a doctor If you have signs or symptoms such as severe chest pain, fainting, sudden onset of shortness of breath or symptoms of a stroke, call [mayoclinic.org]
First, in the elderly, the rate of serious complications from valvulotomy (especially stroke, heart attack, and aortic regurgitation ) is very high. In fact, up to 20% of these patients die before leaving the hospital. [verywell.com]
- Dizziness
[…] become more severe and cause: chest pain brought on by physical activity (angina) – caused by your heart having to work harder shortness of breath – at first you may only notice this when you exercise, but later you may experience this even when resting dizziness [nhs.uk]
[…] with a bicuspid valve are asymptomatic, the most common symptoms include: Shortness of breath, during exercise or when you are lying in bed Constant tiredness or fatigue Coughing at night or when in bed Rapid or fluttering heart palpitations Feeling dizzy [uofmhealthblogs.org]
Symptoms of a stenotic valve include chest pain, shortness of breath and dizziness or fainting caused by inadequate blood flow to the brain. If the bicuspid valve does not close completely, blood can flow backwards into the heart. [my.clevelandclinic.org]
[…] buildup of calcium deposits which causes narrowing Radiation therapy Medications A history of rheumatic fever or high cholesterol Patients with aortic stenosis may have no symptoms or may experience: Chest discomfort Shortness of breath Lightheadedness Dizziness [umcvc.org]
Should a child develop moderate or severe tightness (aortic stenosis) or leaking (aortic regurgitation), or severe dilation of the ascending aorta, he or she might show signs of shortness of breath, exercise intolerance, fatigue, chest pain, dizziness [childheartassociates.com]
Workup
The size of the proximal aorta should be evaluated carefully during the workup. [en.wikipedia.org]
Diagnosis of aortic stenosis is suspected on physical examination (abnormal heart sounds, abnormalities in the pulse) and confirmed by echocardiography. 2,9 (For a detailed description of the history, physical examination, differential diagnosis, and workup [uspharmacist.com]
X-Ray
- Calcified Aortic Valve
In young patients with congenital forms of aortic stenosis, valvulotomy is often a good option. Unfortunately, in older people with heavily calcified aortic valves, the results with valvulotomy have not been good. [verywell.com]
On transthoracic echocardiogram, the parasternal short-axis view showed a calcified aortic valve with probable bicuspid morphology (panel A). [tandfonline.com]
Rare initial symptoms in a patient with aortic stenosis include embolic phenomenon from calcified aortic valve plaques or massive GI bleeding due to angiodysplasia (Heyde’s syndrome). [healio.com]
[…] valvular stenosis (see Reference 20). 6,20,21 In younger patients with mild valvular deformity, the risk of infective endocarditis is higher as compared with older patients with degenerative calcified aortic valves, although it can occur in the geriatric [uspharmacist.com]
Hypertrophy
- Left Ventricular Hypertrophy
A S4 heart sound is also often present due to the severe concentric left ventricular hypertrophy that develops in aortic stenosis. [healio.com]
If there are signs of left ventricular hypertrophy (thickening of the ventricle walls) or arrhythmia in conjunction with moderate stenosis, then the patient should be confined to moderate levels of isotonic exercise and should avoid isometric exercise [pted.org]
Left ventricular hypertrophy is present in bicuspid aortic stenosis. [5] Pathological Findings Images shown below are courtesy of Professor Peter Anderson DVM PhD [6] and published with permission. [wikidoc.org]
His electrocardiogram showed left ventricular hypertrophy with widespread fixed T wave inversion (fig 1). [ncbi.nlm.nih.gov]
Not helpful in screening of BAV Image : “Left ventricular hypertrophy in short axis view.” by Patrick J. Lynch, medical illustrator. [lecturio.com]
Treatment
Conversely, even if no symptoms are present, it may be advisable to proceed with treatment or repairs based on the test results. Possible treatments may include valve repair or valve replacement. [heart.org]
We have vast experience in endovascular treatment, and it may be a treatment option for you. [umcvc.org]
Treatments Like many diseases, bicuspid aortic valve (BAV) will affect each patient differently. [nm.org]
Although surgical correction is a more definitive treatment modality, BAV has a long-term durability and is the treatment of choice in patients presenting early. [louisville.edu]
Prognosis
Prognosis The prognosis depends upon the presence of other complications and how they are treated. Calcified and fibrosed valves are more prone to be stiff or to regurgitate blood back into the heart. [news-medical.net]
Natural History and Prognosis Valvular AS is frequently a progressive disease, the severity increasing over time. [rjmatthewsmd.com]
There is a favorable long-term outcome following aortic valve surgery and relatively low operative risk. 6 This should be considered in light of the prognosis of congestive heart failure in the very old as worse than the prognosis of most cancers ( 1 [uspharmacist.com]
MSCT may be useful in quantifying the valve area and coronary calcification, which aids in assessing prognosis. [patient.info]
Etiology
The University of Michigan is home to the International Registry of Aortic Dissection, and several research laboratories that are exploring the molecular etiologies of aortic diseases. [umcvc.org]
Etiology can be organic or functional. [textbookofcardiology.org]
[…] definition narrowing of the aortic valve Epidemiology demographics bicuspid aortic valve calcification presents at a younger age tricuspid aortic valve calcification > 65 years of age risk factors hypertension coronary artery disease rheumatic heart disease Etiology [medbullets.com]
Etiology – Aortic Stenosis The most common cause of aortic stenosis in a person over age 70 years is calcification of a normal trileaflet aortic valve; this process is sometimes referred to as “senile degeneration.” [healio.com]
The TVT registry does not allow for further details of stroke, but it is reasonable to assume an embolic etiology from the calcified valve itself. [acc.org]
Epidemiology
Introduction Clinical definition narrowing of the aortic valve Epidemiology demographics bicuspid aortic valve calcification presents at a younger age tricuspid aortic valve calcification > 65 years of age risk factors hypertension coronary artery disease [medbullets.com]
Epidemiology of Bicuspid Aortic Valve Disease Bicuspid aortic valve disease is one of the prominent causes of death worldwide and considered one of the most common causes of inherited heart diseases. [lecturio.com]
Complications stemming from structural heart issues are most often treated through surgical intervention, which could include aortic valve replacement, or balloon valvuloplasty. [16] Epidemiology [ edit ] Bicuspid aortic valves are the most common cardiac [en.wikipedia.org]
However, epidemiological studies, histopathological studies and recent experimental evidence have indicated that calcification of the aortic valve is an active biological process rather than a passive process within the leaflet, thus causing regulated [scielo.br]
Epidemiology [ 1 ] AS has become the most frequent type of valvular heart disease in Europe and North America. [patient.info]
Pathophysiology
[…] of the aorta. [1] Pathophysiology of Aortic Stenosis The pathophysiology of aortic stenosis is described in the main chapter on the pathophysiology of aortic stenosis here. [wikidoc.org]
Pharmacotherapy: A Pathophysiologic Approach. 7th ed. New York, NY: McGraw-Hill Inc.; 2008:315-330. 15. Novaro GM, Tiong IY, Pearce GL, et al. [uspharmacist.com]
Cardiol Res Pract. 2012;2012:478259. doi: 10.1155/2012/478259. 26 - Pathophysiological implications of different bicuspid aortic valve configurations. Kari FA, Beyersdorf F, Siepe M. [escardio.org]
1243 Percutaneous Coronary Intervention 1258 Percutaneous Cardiac Procedures 1273 Coronary Artery Bypass Surgery 1290 Approaches to the Patient with Prior Bypass Surgery 1306 Percutaneous Valve Dilatations 1316 Global Pandemic of Heart Failure 1330 Pathophysiology [books.google.com]
This paper article will discuss our current knowledge of the anatomy, pathophysiology, genetics, and clinical aspects of bicuspid aortic valve disease. 1. [hindawi.com]
Prevention
Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. [books.google.com]
Bicuspid Aortic Valve - How to prevent? Bicuspid Aortic Valve - Preparing for surgery Bicuspid Aortic Valve - Post-surgery care Bicuspid Aortic Valve - Other Information [singhealth.com.sg]
Both are safe and effective ways of managing bicuspid aortic stenosis and both prevent the adverse effects described above. [louisville.edu]
Prevention Get prompt treatment for a sore throat that lasts longer than 48 hours, especially if accompanied by a fever. Timely administration of antibiotics may prevent the development of rheumatic fever which can cause valvular heart disease. [hopkinsmedicine.org]
Make sure it's well-controlled to prevent aortic regurgitation. Aug. 02, 2017 [mayoclinic.org]