Lack of weight gain that is normal during pregnancy, or significant weight loss, despite having normal appetite. [hyperthyroidismsymptomsx.com]

Case presentation A 59-year-old Caucasian man was admitted with lethargy and progressive weight loss for 6 to 8 months prior to presentation. [jmedicalcasereports.biomedcentral.com]

Signs and SymptomsSigns and Symptoms – Tremulousness or jitteriness – Exophthalmos – Weight loss despite excellent appetite – hypermetabolic state – Insomnia – Fatigue – Palpitations – Heat intolerance – Sweating – Diarrhea – Deterioration in handwriting [slideshare.net]

Hyperthyroidism can accelerate your body's metabolism, causing unintentional weight loss and a rapid or irregular heartbeat. Several treatments are available for hyperthyroidism. [mayoclinic.org]

These apathetic patients were significantly older and had a longer duration of symptoms and greater weight loss. The study group had a rather typical apathetic, placid, or depressed appearance often thought to represent "old age depression." [annals.org]

Cardiovascular symptoms, atrial fibrillation, and congestive heart failure were common. They typically had evidence of a moderately severe proximal myopathy. Thyromegaly, although usually present, was not prominent and was usually multinodular. [annals.org]

Progression to congestive heart failure, refractory pulmonary edema, circulatory collapse, coma, and death may occur within 72 h. Fever ranges from 38?C (100.4?F) to 41?C (105.8?F). [emjournal.net]

Heart rate faster than 140 beats/min, hypotension, atrial dysrhythmias, congestive heart failure 3. Diarrhea, increased appetite with loss of weight 3. Nausea, vomiting, severe diarrhea, abdominal pain, hepatocellular dysfunction-jaundice 4. [emedicine.medscape.com]

heart failure.  Cardiac hypertrophy has been reported in thyrotoxicosis of different etiologies.  Severe acropachy can be disabling and can lead to total loss of hand function - clubbing of fingers with osteoarthropathy, including periosteal new bone [slideshare.net]

The Japanese Thyroid Association (JTA) criteria categorize patients based on aggregate presence of certain clinical features (CNS, fever, tachycardia, congestive heart failure, GI). [mdcalc.com]

Other symptoms of thyroid storm include chest pain,palpitations, shortness of breath,delirium,confusion, psychosis, stupor, and fatigue. Fatal health complications include heart attack and stroke. [hyperthyroidismsymptomsx.com]

Fatigue B. Palpitations C. Weight Loss D. Heat intolerance E. All the above 42 2. The most common etiology of hyperthyroidism is A. Toxic Multinodular B. Graves C. Toxic Nodular D. Amiodarone induces 43 3. [slideplayer.com]

In fact, I am normally fatigued, low mood etc. This matches the AT descriptions I have been reading. I don't remember any doctors mentioning this. I am wondering whether I should be having any different treatment, or test to confirm this. [healthunlocked.com]

Presentation Symptoms/Physical exam Hypothyroidism Hyperthyroidism Cold intolerance ( heat production) Heat intolerance ( heat production) Weight gain, appetite Weight loss, appetite Hypoactivity, lethargy, fatigue, weakness Hyperactivity Constipation [medbullets.com]

They may include Being nervous or irritable Mood swings Fatigue or muscle weakness Heat intolerance Trouble sleeping Hand tremors Rapid and irregular heartbeat Frequent bowel movements or diarrhea Weight loss Goiter, which is an enlarged thyroid that [icdlist.com]

Atrial arrhythmias frequently are accompanied by high output failure. 64 In hyperthyroid patients older than 75 years, atrial fibrillation has been reported in 32-39% of cases. 52,65 Anginal pain in the absence of coronary atherosclerosis may occur secondary [ahcmedia.com]

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Other possible side effects and complications of radioactive iodine therapy include metallic taste in the mouth, dry mouth, tightness in throat, sore throat, pain in the neck; nausea, vomiting, constipation or diarrhea; fatigue; abnormally high or abnormally [drllynch.com]

Circulation: Tachycardia is common, either sinus tachycardia (most common rhythm) or atrial fibrillation (most common dysrhythmia). Supraventricular and ventricular dysrhythmias, including ventricular fibrillation, may occur. [cdemcurriculum.com]

Cardiac symptoms may include congestive heart failure, which is often refractory to therapy, tachycardia, and a widened pulse pressure. [thebigl.co]

A life-threatening thyrotoxic crisis (ie, thyroid storm) can occur: fever, tachycardia, neurologic abnormalities, and hypertension, followed by hypotension and shock. [slideshare.net]

The most common cardiac manifestations of thyrotoxicosis are resting sinus tachycardia, supraventricular tachycardia including atrial fibrillation and atrial flutter with or without cardiac failure. [jmedicalcasereports.biomedcentral.com]

Tachycardia, fever, hyperkinesis, tremor, proximal myopathy, periodic paralysis, bulbar palsy and hypercalcaemia respond. [aic.cuhk.edu.hk]

His chest X-ray showed cardiomegaly but no pulmonary oedema. However his 12-lead electrocardiogram showed complete heart block with underlying atrial fibrillation (Figure 1 ). [jmedicalcasereports.biomedcentral.com]

Most patients will have weight loss, evidence of cardiomyopathy, myopathy and may have atrial fibrillation, congestive heart failure, cardiomegaly and muscle weakness. Thyroid storm. [ocw.tufts.edu]

The chest radiographic finding noted in some of these patients was essentially that of increased cardiothoracic ratio suggestive of cardiomegaly. [pjms.com.pk]

- Echocardiography, which may disclose a pericardial effusion associated to cardiomegaly, increased thickness of all cardiac walls and reduced cardiac output. - Computed tomography (CT) of the brain that is normal in most patients with primary hypothyroidism [frontiersin.org]

[…] agranulocytosis, granulopenia, and thrombocytopenia), aplastic anemia, drug fever, a lupus-like syndrome (including splenomegaly and vasculitis), periartentis, and hypoprothrombinemia, bleeding, nephritis, glomerulonephritis, interstitial pneumonitis, exfoliative dermatitis [drllynch.com]

vision, protrusion of the eyes, characteristic gaze or stare, double vision (diplopia), all together termed asophthalmopathy. [hyperthyroidismsymptomsx.com]

Usually, these subjects have previously been taking l -thyroxine substitution therapy, unless they have subsequently withdrawn it on their own initiative. [frontiersin.org]

Although β-blockers will rapidly alleviate symptoms in all types of hyperthyroidism, definitive treatment is also necessary, and when euthyroidism is restored β-blockers can be gradually withdrawn. [enetmd.com]

The patient is mentally slow and withdrawn. The skin is dry, coarse, cool, and wrinkled. There may be muscle wasting and proximal myopathy. 53 Weakness in respiratory and skeletal muscles may be factors in decreased exercise tolerance and dyspnea. [ahcmedia.com]

Dementia and severe psychomotor retardation may be the most prominent findings. 60 The Heart in Thyrotoxicosis. Thyrotoxicosis increases the work of the heart. [ahcmedia.com]

Other symptoms of thyroid storm include chest pain,palpitations, shortness of breath,delirium,confusion, psychosis, stupor, and fatigue. Fatal health complications include heart attack and stroke. [hyperthyroidismsymptomsx.com]

Confusion, agitation, delirium, frank psychosis, seizures, stupor or coma Certain unusual presentations include chest pain, acute abdomen, status epilepticus, stroke, acute renal failure due to rhabdomyolysis, and apathetic thyroidism. [emedicine.medscape.com]

On examination, the patient appeared ill, prostrated, and confused. Blood pressure was 190/120 mm Hg, pulse was 148/min and irregular, and respiratory rate was 20/min. Mucous membranes were dry and a pulse deficit of 20 was present. [thefreelibrary.com]

Skin usually moist and warm - confusion, fits, coma, muscle weakness. Very common. Features of UMN lesions have been described as has rhabdomyolysis and sudden onset of thyrotoxic periodic paralysis - arrhythmias, cardiac failure. [aic.cuhk.edu.hk]

Specific Code heart E05.90 - see also Hyperthyroidism Failure, failed Note: heart failure stages A, B, C, and D are based on the American College of Cardiology and American Heart Association stages of heart failure, which complement and should not be confused [icd10data.com]

The patient had a recent history of decreased mentation and apathy, and laboratory findings were found to be consistent with hyperthyroidism. [thefreelibrary.com]

Apathy, or symptoms of depression? Often seen in elderly – apathetic hyperthyroidism. Are there associated cardiovascular complaints? Dyspnea? Chest pain? Acute myocardial infarction can trigger or be triggered by thyroid storm. [cdemcurriculum.com]

Overt thyrotoxic crisis : Fever; extreme agitation and worsening of psychotic symptoms; sometimes somnolence, apathy, or even coma; in some cases, status epilepticus; sudden worsening of cardiovascular symptoms (severe tachycardia, atrial fibrillation [empendium.com]

Apathy, stupor and coma may occur. Laboratory evaluation of thyrotoxicosis begins with a measurement of TSH. If TSH is suppressed ( Figure 1. [ocw.tufts.edu]

Confusion, agitation, delirium, frank psychosis, seizures, stupor or coma Certain unusual presentations include chest pain, acute abdomen, status epilepticus, stroke, acute renal failure due to rhabdomyolysis, and apathetic thyroidism. [emedicine.medscape.com]

Features of thyroid storm: hyperthermia; tachycardia; possible atrial fibrillation; heart failure; GI-hepatic dysfunction: nausea/vomiting, diarrhea, jaundice; altered mental status: agitation, delirium, extreme lethargy, seizure, coma; precipitating [clinicaladvisor.com]

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