A 36-year-old Indian female presented with idiopathic AP. [read.qxmd.com]

Abstract: E1348 Type: Eposter Presentation Background Polycythemia vera (PV) and essential thrombocythemia (ET) are Phi-negative myeloproliferative neoplasms in which arterial or venous thromboses and phenotypical evolutions (leukemia, myelofibrosis) [library.ehaweb.org]

A 38-year-old woman presented with a 6-year history of pruritus predominantly over the lower half of the body after bathing. The pruritus usually started within a minute and regressed after an hour. [ncbi.nlm.nih.gov]

Patients presenting such symptoms were considered “neurotic,” or these symptoms were attributed to individual personality disorders. [thetartan.org]

Video Aquagenic pruritus Presentation Symptoms occur for up to 35 minutes; duration of an attack is typically between 10 and 120 minutes. [wikifeetinfo.blogspot.com]

• Early Satiety

  Questions focus on fatigue, concentration, early satiety, inactivity, night sweats, itching, bone pain, abdominal discomfort, weight loss, and fevers) questionnaire Quality of life through the use of validated questionnaire : the PASYMPLE questionnaire [clinicaltrials.gov]

• Arthritis

  ] Drug-induced aquagenic pruritus has been reported in patients treated with clomipramine (a tricyclic antidepressant), bupropion (prescribed for smoking cessation), and hydroxychloroquine and chloroquine (antimalarial drugs also used for rheumatoid arthritis [rarediseases.info.nih.gov]

  Pruritus Drug-induced Aquagenic Pruritus has been reported in patients treated with clomipramine (a tricyclic antidepressant), bupropion (prescribed for smoking cessation), and hydroxychloroquine and chloroquine(antimalarial drugs also used for rheumatoid arthritis [dovemed.com]

  Arthritis Rheum 1998, 41 (4):744–745. 10.1002/1529-0131(199804)41:4 3.0.CO;2-F 13. Newton JA, Singh AK, Greaves MW, Spry CJ: Aquagenic pruritus associated with the idiopathic hypereosinophilic syndrome. [bmcdermatol.biomedcentral.com]

  The risk of psoriatic arthritis remains constant following initial diagnosis of psoriasis among patients seen in European dermatology clinics. J Eur Acad Dermatol Venereol 2010, 24: 548–554. [medicaljournals.se]

• Complete Blood Count Normal

  blood count (normal or abnormal) [ Time Frame: 1 to 60 days ] number of patients with hematologic remission : hematocrit Quality of life through the use of validated questionnaire : the MPN-SAF (Myeloproliferative Neoplasm Symptom Assessment Form) questionnaire [clinicaltrials.gov]

Since pruritus is a symptom of many serious diseases, it is important to rule out other causes before making a final diagnosis. [10] Treatment [ edit ] Since the cause of the condition cannot be fully avoided in all cases, treatment is usually focused [en.wikipedia.org]

Goodkin R, Bernhard JD: Repeated PUVA treatment of aquagenic pruritus. Clin Exp Dermatol 2002, 27 (2):164–165. 10.1046/j.1365-2230.2002.09805.x 30. Goodkin R, Bernhard JD: Repeated PUVA treatment of aquagenic pruritus. [bmcdermatol.biomedcentral.com]

Aquagenic pruritus could have been the somatic manifestation of the depressive disorder which improved with treatment. [ncbi.nlm.nih.gov]

Repeated PUVA treatment of aquagenic pruritus. Clin Exp Dermatol 2002; 27 (2): 164-5. [29] Smith RA, Ross JS, Staughtion RC. Bath PUVA as treatment for aquaenic pruritus. Br J Derm 1994; 131 (4): 584. [30] Norris JF. [sciencepublishinggroup.com]

[…] of aquagenic pruritus with montelukast. 38 Herman-Kideckel SM...Binkley K 22713437 2012 23 Treatment with propranolol of 6 patients with idiopathic aquagenic pruritus. 38 Nosbaum A...Frances C 21616525 2011 24 Aquagenic pruritus: beneath water "lies" [malacards.org]

(Outcomes/Resolutions) The prognosis of Aquagenic Pruritus is dependent upon the severity of the signs and symptoms and associated complications, if any Addressing the cause of Aquagenic Pruritus may help reduce the symptoms The prognosis may be assessed [dovemed.com]

Myeloproliferative neoplasms - Clinical Keyword(s): Thrombosis, Quality of Life, prognosis, Essential Thrombocytemia [library.ehaweb.org]

The ICP has a good prognosis for the mother with usually rapid recovery after delivery but is associated with adverse fetal outcomes, such as preterm delivery, intrapartum fetal distress, meconium contamination of the amniotic fluid and stillbirth, particularly [zora.uzh.ch]

It can be severe, which may imply a worse prognosis. Excoriations, papules and prurigo nodules from continuous scratching may also be present. [podiatrytoday.com]

Pruritus and Systemic Disease (Overview) of cholestatic pruritus depends on the underlying etiology. [tripdatabase.com]

Pruritus: Etiology and patient evaluation. UpToDate. Waltham, MA: UpToDate; October, 2016; Le Gall-Ianotto C et al. Clinical characteristics of aquagenic pruritus in patients with myeloproliferative neoplasms. Br J Dermatol. [rarediseases.info.nih.gov]

(Etiology) The underlying cause of Aquagenic Pruritus is unknown. In some cases, it is a symptom of polycythemia vera or another underlying condition. Aquagenic Pruritus may precede a diagnosis of polycythemia vera by several years or more. [dovemed.com]

Definition and etiology Pruritus or itch is defined as an unpleasant sensation of the skin that provokes the urge to scratch. [clevelandclinicmeded.com]

Although this is the most common way to acquire the condition, it may also be of unknown etiology. This disorder is not a result of psychiatric or psychological problems, though. [ignoringfriction.blogspot.com]

Epidemiology More common in middle aged males III. Symptoms Intense itching within 15 minutes of water contact Persists on average for 40 minutes IV. Signs No associated skin findings (except excoriations) V. Differential Diagnosis See VI. [tripdatabase.com]

Contact sensititivity reaction to water, 1964) EPIDEMIOLOGY SEX This condition affects women more often than men. According to the literature, both sexes are involved equally in the infantile form of aquagenic urticaria. [flipper.diff.org]

The epidemiology of pruritus depends on its underlying cause or causes. However, in general, the incidence of chronic pruritus increases with age, it is more common in women, and in those of Asian background. [dermnetnz.org]

• Four patients with aquagenic pruritus (AP), one patient with polycythemia rubra vera, one patient with cold urticaria, and three normal control volunteers were studied to better understand the pathophysiology of water-induced itching. [jamanetwork.com]

Ekpe EL, Utomi Mercy Nkemjika, Aquagenic Pruritus: A Review of the Pathophysiology – Beyound Histamine, Central African Journal of Public Health. [sciencepublishinggroup.com]

Pruritus and Systemic Disease (Overview) Pruritus and Systemic Disease: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. [tripdatabase.com]

To date, the pathophysiology and mechanism of action of APE have not been elucidated. [read.qxmd.com]

Back to Top Pathophysiology Peripheral Mechanisms Physical Stimuli and Neural Pathways Itch can be produced by mechanical (gentle touch, pressure, vibration, and wool), thermal and electrical stimuli such as transcutaneous or direct nerve stimulation. [clevelandclinicmeded.com]

The use of cotton clothes and bedding can prevent itch or provide relief to some sufferers. External links There is a support group for sufferers Steinman H, Greaves M (1985). "Aquagenic pruritus". J Am Acad Dermatol. 13 (1): 91–6. PMID 2411768. [wikidoc.org]

The goal of the therapy is the prevention of the common thrombotic events. During the course of the disease, cytoreductive treatment is indicated in most of the patients. [ncbi.nlm.nih.gov]

Sibbald et al. demonstrated that complete removal of the stratum corneum appeared to worsen the reaction, rather than prevent urticaria. [flipper.diff.org]

Review of manuscript Review of the manuscript was performed by the BSH (...) of acute thrombotic events and secondary prevention of thrombosis in PV. [tripdatabase.com]