A 36-year-old Indian female presented with idiopathic AP. [read.qxmd.com]

Abstract: E1348 Type: Eposter Presentation Background Polycythemia vera (PV) and essential thrombocythemia (ET) are Phi-negative myeloproliferative neoplasms in which arterial or venous thromboses and phenotypical evolutions (leukemia, myelofibrosis) [library.ehaweb.org]

Patients presenting such symptoms were considered “neurotic,” or these symptoms were attributed to individual personality disorders. [thetartan.org]

A 38-year-old woman presented with a 6-year history of pruritus predominantly over the lower half of the body after bathing. The pruritus usually started within a minute and regressed after an hour. [ncbi.nlm.nih.gov]

Video Aquagenic pruritus Presentation Symptoms occur for up to 35 minutes; duration of an attack is typically between 10 and 120 minutes. [wikifeetinfo.blogspot.com]

• Hodgkin Lymphoma

  Aquagenic pruritus in a patient associated with myelodysplasia and T-cell non-Hodgkin's lymphoma. J Am Acad Dermatol. 2002; 46 :144–5. [ PubMed ] [ Google Scholar ] 5. Gregor M. Aquagenic pruritus and hepatitis. [ncbi.nlm.nih.gov]

  lymphoma. 38 Khalifa N...Black AK 11756965 2002 44 Aquagenic pruritus relieved by tight fitting clothing. 38 Spelman L...Dicker T 11400693 2001 45 Aquagenic pruritus responding to intermittent photochemotherapy. 38 Holme SA...Anstey AV 11260176 2001 [malacards.org]

  Aquagenic Pruritus in a patient with myelodysplastic and T-cell non-Hodgkin’s Lymphoma. Journal of the American Academy of Dermatology. 2002: 46: 144-145. [12] Ferguson JE, August PJ, Guy AJ. [sciencepublishinggroup.com]

  Paraneoplastic itch is associated with lymphoma, especially Hodgkin lymphoma, leukaemia or a solid organ tumour (eg lung, colon, brain). [dermnetnz.org]

  Khalifa N, Singer CR, Black AK: Aquagenic pruritus in a patient associated with myelodysplasia and T-cell non-Hodgkin's lymphoma. J Am Acad Dermatol 2002, 46 (1):144–145. 10.1067/mjd.2001.117391 9. [bmcdermatol.biomedcentral.com]

• Falling

  All the while, I'm expected to continue living every day whilst dodging the heat (in case I sweat) and any contact with water (even though it happens to fall from the sky nearly every day) #help #allergicreaction #aquagenicurticaria #aquagenicpruritus [justgiving.com]

  Niah, from Hastings, East Sussex, has symptoms so intense that she will often fall-asleep from exhaustion after a reaction, and has been left housebound. [mirror.co.uk]

  Her symptoms are so intense that she will often fall-asleep from exhaustion after a reaction, and has been left housebound apart from trying to sort out medications. [storytrender.com]

  Later that day, scorching drops of the stuff start falling from the sky. At the local leisure centre, she watches others splash around in a pool of the irritant. They seem unfazed, but the moment she dips her toe in, she’s faced with burning pain. [bbc.com]

  The H1 antihistamines fall into three categories including: first-generation (classic, marked sedative and anticholinergic actions; second-generation (low sedation); and third-generation (minimal or no sedation) antihistamines. [podiatrytoday.com]

• Weight Loss

  Questions focus on fatigue, concentration, early satiety, inactivity, night sweats, itching, bone pain, abdominal discomfort, weight loss, and fevers) questionnaire Quality of life through the use of validated questionnaire : the PASYMPLE questionnaire [clinicaltrials.gov]

  Patients may report headache, visual disturbances, weight loss, night sweats, and vertigo. Other symptoms include redness, warmth, and pain (erythromelalgia) of the digits. [skinsolutionsderm.com]

  Review of Systems A detailed history is important in chronic pruritus of unknown origin, including general health (fever, chills, weight loss); skin (pigmentation, sweating, asteatosis, plethora, and jaundice); hair (growth, texture, loss); nails (Beau's [clevelandclinicmeded.com]

• Pallor

  […] cooling (localized or systemic) Delayed pressure urticaria Sustained perpendicular pressure Solar urticaria Ultraviolet or visible solar radiation Localized heat urticaria Local heat contact Adrenergic urticaria (red papular wheals with surrounding pallor [clinicalgate.com]

  • Hematologic pruritus: Patients with iron deficiency may have pallor if they have anemia; they might also have glossitis and angular cheilitis. [skinsolutionsderm.com]

• Chills

  […] underlying skin or internal disease, topical treatment may include: Wet dressings or tepid shower to cool the skin Calamine lotion (contains phenol, which cools the skin): avoid on dry skin and limit use to a few days Menthol/camphor lotion: gives a chilling [dermnetnz.org]

  Review of Systems A detailed history is important in chronic pruritus of unknown origin, including general health (fever, chills, weight loss); skin (pigmentation, sweating, asteatosis, plethora, and jaundice); hair (growth, texture, loss); nails (Beau's [clevelandclinicmeded.com]

• Dyspnea

  Patients with AP reported reduced global health status and higher fatigue, pain, and dyspnea Full Text available with Trip Pro 2013 American journal of hematology 10. [tripdatabase.com]

• Pruritus Ani

  This question featured in : Pruritus ani treatment Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. [practo.com]

  Aquagenic pruritus presents with severe pruritus or a stinging, tingling, or burning sensation without any visible skin changes... [read.qxmd.com]

  […] reasons for pruritus About 2% of pregnant women have pruritus without any obvious dermatological cause. [dermnetnz.org]

• Jaundice

  It is present in approximately 25% of patients with jaundice and in 50% of patients receiving renal dialysis. Sex The sex of the patient does not seem to be associated with pruritus in systemic diseases. [skinsolutionsderm.com]

  Review of Systems A detailed history is important in chronic pruritus of unknown origin, including general health (fever, chills, weight loss); skin (pigmentation, sweating, asteatosis, plethora, and jaundice); hair (growth, texture, loss); nails (Beau's [clevelandclinicmeded.com]

  Other causes include hepatic disease, pregnancy with intrahepatic cholestasis, obstructive jaundice, primary biliary cirrhosis, drug-induced cholestasis such as intrahepatic biliary obstruction due to chlorpromazine, contraceptive pills and testosterone [podiatrytoday.com]

• Tingling

  The only side effect I get is a flushing or tingle feeling on my skin for maybe ten minutes after taking it. One person commented on having GI trouble, but it actually made my belly feel better. [groups.io]

  Aquagenic pruritus presents with severe pruritus or a stinging, tingling, or burning sensation without any visible skin changes... [read.qxmd.com]

  This is an extremely common cause of generalized pruritus that is characterized by the development of severe, prickling like, tingling or burning skin lesion and is evoked by contact with water [ 2 ]. [bmcdermatol.biomedcentral.com]

  E-mail: [email protected] Aquagenic pruritus (AP) is a debilitating dermal condition characterized by the development of intense itching, stinging, tingling or burning sensations, without observable skin lesions, brought on by contact with [medicaljournals.se]

• Thrombocytosis

  Chronisch-myeloproliferative Erkrankungen: PVR-ET-OMF Stellenwert des Xagrid® in der Therapie der myeloproliferativen Erkrankungen Onko-Treff, Hamburg 29.11.2006 Vorträge 2004 Prof.Dr.P.E.Petrides: Results of clinical studies in the treatment of of thrombocytosis [onkologiemuenchen.de]

Since pruritus is a symptom of many serious diseases, it is important to rule out other causes before making a final diagnosis. [10] Treatment [ edit ] Since the cause of the condition cannot be fully avoided in all cases, treatment is usually focused [en.wikipedia.org]

[…] of aquagenic pruritus with montelukast. 38 Herman-Kideckel SM...Binkley K 22713437 2012 23 Treatment with propranolol of 6 patients with idiopathic aquagenic pruritus. 38 Nosbaum A...Frances C 21616525 2011 24 Aquagenic pruritus: beneath water "lies" [malacards.org]

Repeated PUVA treatment of aquagenic pruritus. Clin Exp Dermatol 2002; 27 (2): 164-5. [29] Smith RA, Ross JS, Staughtion RC. Bath PUVA as treatment for aquaenic pruritus. Br J Derm 1994; 131 (4): 584. [30] Norris JF. [sciencepublishinggroup.com]

I was promised treatment by the NHS in December 2016. I am still waiting for the treatment to start now. [justgiving.com]

Treatment Treatments can include applying capsaicin cream on the affected areas, and Ultraviolet-B Phototherapy. Some people utilize tanning beds to accomplish such treatment, but skin cancer can become a concern for frequent tanning. [wikidoc.org]

(Outcomes/Resolutions) The prognosis of Aquagenic Pruritus is dependent upon the severity of the signs and symptoms and associated complications, if any Addressing the cause of Aquagenic Pruritus may help reduce the symptoms The prognosis may be assessed [dovemed.com]

Myeloproliferative neoplasms - Clinical Keyword(s): Thrombosis, Quality of Life, prognosis, Essential Thrombocytemia [library.ehaweb.org]

The ICP has a good prognosis for the mother with usually rapid recovery after delivery but is associated with adverse fetal outcomes, such as preterm delivery, intrapartum fetal distress, meconium contamination of the amniotic fluid and stillbirth, particularly [zora.uzh.ch]

It can be severe, which may imply a worse prognosis. Excoriations, papules and prurigo nodules from continuous scratching may also be present. [podiatrytoday.com]

Pruritus and Systemic Disease (Overview) of cholestatic pruritus depends on the underlying etiology. [tripdatabase.com]

Pruritus: Etiology and patient evaluation. UpToDate. Waltham, MA: UpToDate; October, 2016; Le Gall-Ianotto C et al. Clinical characteristics of aquagenic pruritus in patients with myeloproliferative neoplasms. Br J Dermatol. [rarediseases.info.nih.gov]

(Etiology) The underlying cause of Aquagenic Pruritus is unknown. In some cases, it is a symptom of polycythemia vera or another underlying condition. Aquagenic Pruritus may precede a diagnosis of polycythemia vera by several years or more. [dovemed.com]

Definition and etiology Pruritus or itch is defined as an unpleasant sensation of the skin that provokes the urge to scratch. [clevelandclinicmeded.com]

Although this is the most common way to acquire the condition, it may also be of unknown etiology. This disorder is not a result of psychiatric or psychological problems, though. [ignoringfriction.blogspot.com]

Epidemiology More common in middle aged males III. Symptoms Intense itching within 15 minutes of water contact Persists on average for 40 minutes IV. Signs No associated skin findings (except excoriations) V. Differential Diagnosis See VI. [tripdatabase.com]

Contact sensititivity reaction to water, 1964) EPIDEMIOLOGY SEX This condition affects women more often than men. According to the literature, both sexes are involved equally in the infantile form of aquagenic urticaria. [flipper.diff.org]

The epidemiology of pruritus depends on its underlying cause or causes. However, in general, the incidence of chronic pruritus increases with age, it is more common in women, and in those of Asian background. [dermnetnz.org]

• Four patients with aquagenic pruritus (AP), one patient with polycythemia rubra vera, one patient with cold urticaria, and three normal control volunteers were studied to better understand the pathophysiology of water-induced itching. [jamanetwork.com]

Ekpe EL, Utomi Mercy Nkemjika, Aquagenic Pruritus: A Review of the Pathophysiology – Beyound Histamine, Central African Journal of Public Health. [sciencepublishinggroup.com]

Pruritus and Systemic Disease (Overview) Pruritus and Systemic Disease: Background, Pathophysiology, Etiology Edition: No Results No Results Please confirm that you would like to log out of Medscape. [tripdatabase.com]

To date, the pathophysiology and mechanism of action of APE have not been elucidated. [read.qxmd.com]

Back to Top Pathophysiology Peripheral Mechanisms Physical Stimuli and Neural Pathways Itch can be produced by mechanical (gentle touch, pressure, vibration, and wool), thermal and electrical stimuli such as transcutaneous or direct nerve stimulation. [clevelandclinicmeded.com]

The use of cotton clothes and bedding can prevent itch or provide relief to some sufferers. External links There is a support group for sufferers Steinman H, Greaves M (1985). "Aquagenic pruritus". J Am Acad Dermatol. 13 (1): 91–6. PMID 2411768. [wikidoc.org]

The goal of the therapy is the prevention of the common thrombotic events. During the course of the disease, cytoreductive treatment is indicated in most of the patients. [ncbi.nlm.nih.gov]

Sibbald et al. demonstrated that complete removal of the stratum corneum appeared to worsen the reaction, rather than prevent urticaria. [flipper.diff.org]

Review of manuscript Review of the manuscript was performed by the BSH (...) of acute thrombotic events and secondary prevention of thrombosis in PV. [tripdatabase.com]