However, the present work has some limitations. [jstage.jst.go.jp]

Acute arsenic intoxication presenting as Guillain-Barre-like syndrome. Muscle and Nerve, 10 (2), 114-120. DOI: 10.1002/mus.880100203 Acute arsenic intoxication presenting as Guillain-Barre-like syndrome. / Donofrio, P. D.; Wilbourn, A. [experts.umich.edu]

In developing its educational products ATSDR has made a diligent effort to ensure the accuracy and the currency of the presented information. [atsdr.cdc.gov]

However, Sjögren syndrome sometimes presents with sensory neuropathy or ganglioneuritis. Ribosomal P antibody may be present in these individuals. [questdiagnostics.com]

Material and methods In the present study, 20 samples of opium were analysed for the presence of arsenic. [unodc.org]

• Burning Feet

  […] and motor weakness (most common presentation) Burning-foot syndrome : ↓ fine touch, vibration :, pain, tingling, pins-and-needles sensation or formication. [amboss.com]

  Tricyclic antidepressants such as amitriptyline or anticonvulsants such as gabapentin are useful for relief of neuropathic pain (eg, diabetic burning feet). [merckmanuals.com]

  The associated pain or pins-and-needles, burning, crawling, or prickling sensations form a typical "stocking" distribution in the feet and lower legs. [medical-dictionary.thefreedictionary.com]

• Anosmia

  […] unusually rapid heart beat (tachycardia); low levels of iron within the red blood cells (anemia); bluish discoloration (cyanosis) of the skin and mucous membranes due to insufficient oxygen supply to these tissues; and/or an impaired sense of smell (anosmia [rarediseases.org]

• Numbness of the Feet

  Malnutrition and alcohol abuse Burning, stabbing pains and numbness in the feet, and sometimes in the hands, are distinguishing features of alcoholic neuropathy. [medical-dictionary.thefreedictionary.com]

• Dysesthesia

  The common symptoms are as follows: numbness and/or tingling of extremities; burning or electric pain; dysesthesia; trouble with balance; dizziness; vision changes; and so on. [synapse.koreamed.org]

  Small-fiber neuropathies often present with burning pain, lightning-like or lancinating pain, aching, or uncomfortable paresthesias (dysesthesias). [aafp.org]

  Loss of function “- symptoms” Disordered function “+ symptoms” Sensory “Large Fiber” ↓ Vibration ↓ Proprioception Hyporeflexia Sensory ataxia Paresthesias Sensory “Small Fiber” ↓ Pain ↓ Temperature Dysesthesias Allodynia The clinical response to sensory [slideshare.net]

  Sensory effects, particularly painful dysesthesia, occur earlier and may predominate in moderate poisoning, whereas ascending weakness and paralysis may predominate in more severe poisoning. [lectrochi.com]

  In addition to sensory loss, patients often complain of paresthesias and dysesthesias, often characterized by a sense of numbness, tingling, prickling, and pins-and-needles sensations. [clevelandclinicmeded.com]

• Decreased Ankle Reflex

  decreased ankle reflexes is less valuable for diagnosis. [aafp.org]

What is the treatment for peripheral neuropathy and its symptoms? Can peripheral neuropathy be cured? The treatment for peripheral neuropathy depends on its cause. The first step in treatment is, therefore, to look for the cause. [medicinenet.com]

For the treatment of DN, tight glucose control should be preceded [ 5 ]. [synapse.koreamed.org]

Despite treatment with succimer meso-2,3-dimercaptosuccinic acid, her neuropathy progressed to ventilator dependence and quadriplegia. [ncbi.nlm.nih.gov]

Fortunately, treatment can be very helpful in the management of neuropathy symptoms. But before any treatment can begin, the most important step is to determine the underlying cause of the neuropathy to plan the correct course of treatment. [mollysfund.org]

Treatment Definitive therapy : treat the underlying disease! [amboss.com]

Prognosis varies depending on the severity of nerve damage done by the medication. Conclusions As described in this review, there are many different kinds of polyneuropathies although their symptoms and signs might look similar. [synapse.koreamed.org]

Pregnancy and breast-feeding: arsenic is probably transferred to the baby via the placenta and breast milk. [ 2 ] Prognosis [ 2 ] The prognosis varies with the amount and rate of arsenic ingestion. [patient.info]

Lancet I: 791–794 Google Scholar Juntunen J, Antti-Poika M, Tola S, et al. (1982) Clinical prognosis of patients with diagnosed chronic solvent intoxication. [link.springer.com]

Prognosis  Each patient's prognosis depends on the severity of the neuropathy when exposure is ceased or reduced to levels that will not affect health negatively. 44. [slideshare.net]

Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]

Diagnostic tests, usually beginning electrodiagnostic testing, are indicated in patients with atypical clinical features, unknown etiology, and/or severe or rapidly progressive symptoms. [amboss.com]

Though the etiological agent could not be confirmed with investigations, probable toxin induced polyneuropathy due to arsenic still remains the most likely diagnosis. [annalsofneurosciences.org]

[…] various forms of polyneuropathy are categorized by the type of nerve affected (e.g., sensory, motor, or autonomic), by the distribution of nerve injury (e.g., distal vs. proximal), by nerve component primarily affected (e.g., demyelinating vs. axonal), by etiology [fpnotebook.com]

We conducted an open label study of patients with peripheral neuropathy of multiple etiologies. [practicalpainmanagement.com]

Epidemiologic Reviews, 16 (2), 184-209 (1994). Enterline, P. E. and Marsh, G. M., Cancers among workers exposed to arsenic and other substances in a copper smelter. American Journal of Epidemiology, 116 (6), 895-911 (1982). Falk, H., Caldwell, G. [consultox.com]

Epidemiological evidence indicates that chronic arsenic exposure is associated with vasospasm and peripheral vascular insufficiency. [lectrochi.com]

[…] table Free element of arsenic appears in two allotropic forms: grey and yellow (crystalline) Can also exist in various oxidation states, inorganic and organic forms, exposure to inorganic arsenic is associated with most cases of arsenic induced toxicity Epidemiology [pathologyoutlines.com]

Lead  Epidemiology of lead toxicity  Common in children: Especially black non-hispanic children (22%)  Most common in homes built from 1920 to 1950  Identical twins often have concordant lead levels  Lead neuropathy: Especially from industrial exposure [slideshare.net]

Causation and causal inference in epidemiology. Am J Public Health 95 (Suppl 1): S144–50, 2005. Dalakas MC. Peripheral neuropathy and antiretroviral drugs. J Periph N Syst 6:14-20, 2001. Gaist D, Jeppesen U, Anderson M, et al. [now.aapmr.org]

[…] is present in air, usually due to volcanic eruption and purposeful human activities Arsenic also found as sulphuric compound in lead, copper, nickel and ferrous ores; also in soil in small quantities Also a medicinal used by physicians for 2000 years Pathophysiology [pathologyoutlines.com]

Our grasp of the pathophysiologic basis of the clinical PN has increased rapidly, but these advances are primarily descriptive and little progress has been made in understanding the fundamental pathogenic events that underlie the polyneuropathies. [practicalpainmanagement.com]

Because pathophysiology and symptoms are related, polyneuropathies are often classified by area of dysfunction: Myelin Vasa nervorum Axon Polyneuropathies may be acquired or inherited. [merckmanuals.com]

Pathophysiology Although peripheral neuropathy has multiple etiologies, the nerve has a limited number of ways to respond to injury. 4, 5 The damage can occur at the level of the axon (i.e., axonopathy). [aafp.org]

The exact pathophysiology of arsenic toxicity is not known, but it has been suggested that arsenic is primarily toxic to the cell body; segmental demyelination occurs prior to axonal degeneration 1 ). [jstage.jst.go.jp]

Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]

Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. [books.google.de]

SLIDESHOW Diabetic Peripheral Neuropathy: Improve Diabetes Nerve Pain See Slideshow Can peripheral neuropathy be prevented? Certain forms of peripheral neuropathy can be prevented. [medicinenet.com]

Phenytoin, which is prescribed to prevent seizures, and disulfiram, which is given to fight alcohol addition, both have been linked to peripheral neuropathy. [livestrong.com]