Symptoma

Arsenic-Induced Polyneuropathy

Polyneuropathy Arsenic Ind

It details the typical pathological features of each disease by presenting color photographs and example cases that provide a brief clinical history and pertinent electrophysiological and other laboratory data. [books.google.de]

Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. [books.google.com]

However, the present work has some limitations. [jstage.jst.go.jp]

  • Disability

    This market-leading text covers everything from basic examination and psychological assessment to electrodiagnosis, therapeutic exercise, orthotics and assistive devices, and in-depth clinical management of the full range of childhood disabilities and [books.google.com]

    The disorder does not usually cause life-threatening complications, but it can be uncomfortable or disabling. [medlineplus.gov]

    According to US governmental agencies, mercury and other heavy metals cause adverse health effects and learning disabilities in millions of people in the United States each year. The elderly and children are especially susceptible. [nervedoctor.info]

    If the cause cannot be corrected, treatment focuses on minimizing disability and pain. Physical and occupational therapists can recommend useful assistive devices. [merckmanuals.com]

    Heavy metals, solvents and pesticides, among other chemicals, may induce such disability. [file.scirp.org]

  • Burning Feet

    feet syndrome with worsening of symptoms at night Cranial nerve involvement is very common (especially of the oculomotor and abducens nerve ) Trophic skin changes ; (due to autonomic neuropathy ): anhidrosis ;, edema, ulcers Autonomic features: erectile [amboss.com]

    Tricyclic antidepressants such as amitriptyline or anticonvulsants such as gabapentin are useful for relief of neuropathic pain (eg, diabetic burning feet). [merckmanuals.com]

    For example, painful, burning feet may be a symptom of alcohol abuse, diabetes, HIV infection, or an underlying malignant tumor, among other causes. Without further details, effective treatment would be difficult. [medical-dictionary.thefreedictionary.com]

  • Gastric Lavage

    Gastric lavage: consider if a significant amount has been ingested Whole bowel irrigation with polyethylene glycol may be used to prevent arsenic absorption. [patient.info]

  • Anosmia

    […] unusually rapid heart beat (tachycardia); low levels of iron within the red blood cells (anemia); bluish discoloration (cyanosis) of the skin and mucous membranes due to insufficient oxygen supply to these tissues; and/or an impaired sense of smell (anosmia [rarediseases.org]

  • Failure to Thrive

    Fred Ferri’s popular "5 books in 1" format provides quick guidance on menorrhagia, Failure to Thrive (FTT), Cogan’s syndrome, and much more. [books.google.com]

  • Tinnitus

    COBALT POISONING Cobalt, used in making jet engines, may cause nausea, vomiting, lack of appetite (anorexia), ear ringing (tinnitus), nerve damage, respiratory diseases, an unusually large thyroid gland (goiter), and/or heart and/or kidney damage. [rarediseases.org]

  • Desquamating Rash

    Chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (Mees) lines in the fingernails. (Adams et al., Principles of Neurology, 6th ed, p1212) [xmri.com]

    Chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (Mees) lines in the fingernails. [connects.catalyst.harvard.edu]

  • Numbness of the Feet

    Malnutrition and alcohol abuse Burning, stabbing pains and numbness in the feet, and sometimes in the hands, are distinguishing features of alcoholic neuropathy. [medical-dictionary.thefreedictionary.com]

  • Myopathy

    Causes of generalized weakness include motor neuron disease, disorders of the neuromuscular junction and myopathy. Peripheral neuropathy can also be mimicked by myelopathy, syringomyelia or dorsal column disorders, such as tabes dorsalis. [aafp.org]

  • Dysesthesia

    The common symptoms are as follows: numbness and/or tingling of extremities; burning or electric pain; dysesthesia; trouble with balance; dizziness; vision changes; and so on. [synapse.koreamed.org]

    Small-fiber neuropathies often present with burning pain, lightning-like or lancinating pain, aching, or uncomfortable paresthesias (dysesthesias). [aafp.org]

    Loss of function “- symptoms” Disordered function “ symptoms” Sensory “Large Fiber” Vibration Proprioception Hyporeflexia Sensory ataxia Paresthesias Sensory “Small Fiber” Pain Temperature Dysesthesias Allodynia The clinical response to sensory nerve [slideshare.net]

    Sensory effects, particularly painful dysesthesia, occur earlier and may predominate in moderate poisoning, whereas ascending weakness and paralysis may predominate in more severe poisoning. [lectrochi.com]

    In addition to sensory loss, patients often complain of paresthesias and dysesthesias, often characterized by a sense of numbness, tingling, prickling, and pins-and-needles sensations. [clevelandclinicmeded.com]

  • Meningism

    Ferri’s popular "5 books in 1" format provides quick guidance on short QT syndrome, microscopic polyangiitis, fungal meningitis, and much more. This medical reference makes the answers you need even easier to find - anytime, anywhere. [books.google.com]

    There were no signs of meningeal irritation and systemic examination did not reveal any abnormality. Investigations revealed anemia with hemoglobin of 10.3 gm%. [annalsofneurosciences.org]

    View/Print Table TABLE 4 Neuropathies with Less Common Patterns of Involvement Neuropathies with cranial nerve involvement Diabetes mellitus Guillain-Barré syndrome HIV/AIDS Lyme disease Sarcoidosis Neoplastic invasion of skull base or meninges Diphtheria [aafp.org]

  • Decreased Ankle Reflex

    decreased ankle reflexes is less valuable for diagnosis. [aafp.org]

The textbookprovides an evidence-based approach to testing, differential diagnosis, and treatment, and should serveas a trusted resource for healthcare professionals confronting the many manifestations of peripheralneuropathy in clinical practice. [books.google.com]

What is the treatment for peripheral neuropathy and its symptoms? Can peripheral neuropathy be cured? The treatment for peripheral neuropathy depends on its cause. The first step in treatment is, therefore, to look for the cause. [medicinenet.com]

For the treatment of DN, tight glucose control should be preceded [ 5 ]. [synapse.koreamed.org]

Despite treatment with succimer meso-2,3-dimercaptosuccinic acid, her neuropathy progressed to ventilator dependence and quadriplegia. [ncbi.nlm.nih.gov]

Fortunately, treatment can be very helpful in the management of neuropathy symptoms. But before any treatment can begin, the most important step is to determine the underlying cause of the neuropathy to plan the correct course of treatment. [mollysfund.org]

Prognosis varies depending on the severity of nerve damage done by the medication. Conclusions As described in this review, there are many different kinds of polyneuropathies although their symptoms and signs might look similar. [synapse.koreamed.org]

Pregnancy and breast-feeding: arsenic is probably transferred to the baby via the placenta and breast milk. [ 2 ] Prognosis [ 2 ] The prognosis varies with the amount and rate of arsenic ingestion. [patient.info]

Lancet I: 791–794 Google Scholar Juntunen J, Antti-Poika M, Tola S, et al. (1982) Clinical prognosis of patients with diagnosed chronic solvent intoxication. [link.springer.com]

Prognosis  Each patient's prognosis depends on the severity of the neuropathy when exposure is ceased or reduced to levels that will not affect health negatively. 44. [slideshare.net]

Code First Code First Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]

Diagnostic tests, usually beginning electrodiagnostic testing, are indicated in patients with atypical clinical features, unknown etiology, and/or severe or rapidly progressive symptoms. [amboss.com]

Though the etiological agent could not be confirmed with investigations, probable toxin induced polyneuropathy due to arsenic still remains the most likely diagnosis. [annalsofneurosciences.org]

We conducted an open label study of patients with peripheral neuropathy of multiple etiologies. [practicalpainmanagement.com]

demyelinating vs. axonal), by etiology, or by pattern of inheritance. [fpnotebook.com]

Epidemiologic Reviews, 16 (2), 184-209 (1994). Enterline, P. E. and Marsh, G. M., Cancers among workers exposed to arsenic and other substances in a copper smelter. American Journal of Epidemiology, 116 (6), 895-911 (1982). Falk, H., Caldwell, G. [consultox.com]

Epidemiological evidence indicates that chronic arsenic exposure is associated with vasospasm and peripheral vascular insufficiency. [lectrochi.com]

[…] table Free element of arsenic appears in two allotropic forms: grey and yellow (crystalline) Can also exist in various oxidation states, inorganic and organic forms, exposure to inorganic arsenic is associated with most cases of arsenic induced toxicity Epidemiology [pathologyoutlines.com]

Causation and causal inference in epidemiology. Am J Public Health 95 (Suppl 1): S144–50, 2005. Dalakas MC. Peripheral neuropathy and antiretroviral drugs. J Periph N Syst 6:14-20, 2001. Gaist D, Jeppesen U, Anderson M, et al. [now.aapmr.org]

Lead  Epidemiology of lead toxicity  Common in children: Especially black non-hispanic children (22%)  Most common in homes built from 1920 to 1950  Identical twins often have concordant lead levels  Lead neuropathy: Especially from industrial exposure [slideshare.net]

[…] is present in air, usually due to volcanic eruption and purposeful human activities Arsenic also found as sulphuric compound in lead, copper, nickel and ferrous ores; also in soil in small quantities Also a medicinal used by physicians for 2000 years Pathophysiology [pathologyoutlines.com]

Our grasp of the pathophysiologic basis of the clinical PN has increased rapidly, but these advances are primarily descriptive and little progress has been made in understanding the fundamental pathogenic events that underlie the polyneuropathies. [practicalpainmanagement.com]

Because pathophysiology and symptoms are related, polyneuropathies are often classified by area of dysfunction: Myelin Vasa nervorum Axon Polyneuropathies may be acquired or inherited. [merckmanuals.com]

Pathophysiology Although peripheral neuropathy has multiple etiologies, the nerve has a limited number of ways to respond to injury. 4, 5 The damage can occur at the level of the axon (i.e., axonopathy). [aafp.org]

The exact pathophysiology of arsenic toxicity is not known, but it has been suggested that arsenic is primarily toxic to the cell body; segmental demyelination occurs prior to axonal degeneration 1 ). [jstage.jst.go.jp]

Rapidly find the answers you need with separate sections on diseases and disorders, differential diagnosis, clinical algorithms, laboratory results, and clinical preventive services, plus an at-a-glance format that uses cross-references, outlines, bullets [books.google.com]

Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. [books.google.de]

SLIDESHOW Diabetic Peripheral Neuropathy: Improve Diabetes Nerve Pain See Slideshow Can peripheral neuropathy be prevented? Certain forms of peripheral neuropathy can be prevented. [medicinenet.com]