Here we report a rare case of arsenical keratosis presented with multiple polymorphic eruptions combined with chloracne. [tandfonline.com]

This study presents the case of a 38-year-old patient from Pakistan with vitiligo, who developed multiple verrucous papules on the palms and soles several years after receiving "herbal treatment" from a travelling Indian doctor for a period of 12 months [ncbi.nlm.nih.gov]

Arsenicism is a systemic disease that can present with cutaneous, neurologic, and/or gastrointestinal symptoms. Acute arsenic toxicity most commonly presents with gastrointestinal symptoms with nausea, vomiting, and diarrhea. [clinicaladvisor.com]

ArKs may also present as slightly elevated, erythematous, scaly or pigmented plaques. [dermaamin.com]

• Palmoplantar Keratosis

  PUVA can be used for eczematized palmoplantar keratosis treatment. Suggestions Surgery and CO2 laser can treat local severe palmoplantar keratosis [waitall.com]

  Whenever a patient presents with palmoplantar keratosis, chronic arsenic poisoning should be part of the differential. [doi.org]

• Leukonychia

  The prevalence rates of Mee lines (transverse bands of leukonychia) on the nails, arsenic keratoses, and pigment disorders among these patients were 86.1%, 77.2%, and 67.8%, respectively. [20] Race Several large studies have focused in regional endemic [emedicine.medscape.com]

• Palmar Keratosis

  keratosis Patient voluntarily agreed to participate Patient did not receive topical application of any drug for the last three months Patient who understood the instructions of applying drug and could apply drug as per as instructions - Exclusion Criteria [clinicaltrials.gov]

• Koilonychia

  Changes of finger nails often present as Mees’ lines or koilonychia. High incidence of multiple carcinomas such as squamous-cell carcinoma and basal cell carcinoma are documented [8]. [tandfonline.com]

• Desquamating Rash

  Chronic exposure is associated with mucosal irritation, desquamating rash, myalgias, peripheral neuropathy, and white transverse (Mees) lines in the fingernails. [bioportfolio.com]

Workup may include: CBC with differential, liver function tests, renal function tests, blood and urine arsenic levels. Arsenic levels in tissue, hair and nails can be performed, but may be normal if only distant exposure. [wiydx.com]

A thorough history and physical examination should be performed and further imaging and workup should be based on these findings. [clinicaladvisor.com]

• Pseudomonas

  The growth of Pseudomonas spp. increased in different sites of the skin. But in patient of arsenicosis, the skin of the palm shows the growth of Enterobacter spp. Downloads Download data is not yet available. [banglajol.info]

• Intranuclear Inclusion Bodies

  Vacuolated cells were demonstrated by light microscopy, while the characteristic electron microscopic features of both lesions were the appearance of nuclear bodies and the presence of radially arranged, intranuclear inclusion bodies of high electron [karger.com]

Read more about this topic: Arsenical Keratosis Other articles related to " treatment, treatments ": Sleep Disorder - General Principles of Treatment ... [liquisearch.com]

There is no such study where effects of antimicrobials have been evaluated as the treatment of arsenical keratosis. [clinicaltrials.gov]

The recommended dosing regime is several treatment pulses, which are separated by several 4-day periods without treatment. PUVA can be used for eczematized palmoplantar keratosis treatment. [waitall.com]

Treatment with oral etretinate is reported in a case of arsenical keratosis with Bowen's disease. Good (80%) clearance in keratoses was obtained, which is maintained after 15 months' follow up. [ncbi.nlm.nih.gov]

Side effects associated with these treatments are inflammation, oozing, ulceration, crusting, pain, hypo/hyperpigmentation, and treatment failure. Surgical excision can be performed for arsenical keratoses. [clinicaladvisor.com]

The prognosis of Arsenical Keratosis is generally excellent with suitable early treatment Who gets Arsenical Keratosis? (Age and Sex Distribution) Arsenical Keratosis usually forms over many decades (20-30 years). [dovemed.com]

Prognosis and Clinical Course ArKs and arsenical-induced BD tend to persist for many years, and progression to invasive SCC is believed to be relatively rare. [dermaamin.com]

Pregnancy and breast-feeding: arsenic is probably transferred to the baby via the placenta and breast milk. [ 2 ] Prognosis [ 2 ] The prognosis varies with the amount and rate of arsenic ingestion. [patient.info]

Léčba this psoriázy arrow-down Epidemiology Pustcular a rozsáhlá ložisková psoriáza Visual třetí arrow-down Presentation arrow-down Differential diagnosis arrow-down Psoriázy arrow-down Complications arrow-down Prognosis arrow-down Palmoplantar pustulosis [omycoricy.ga]

Epithelioma of the back of the hand is usually responsive to proper measures, but the prognosis is not so favorable as with the ordinary face cases, and axillary gland involve ment sometimes presents early. [doctortreatments.com]

Bowen's precancerous dermatosis and multiple benign superficial epithelioma; evidence of arsenic as an etiological agent Anderson, Anderson Arsenical epitheliomas of medicinal origin Arhelger, Arhelger; Kremen, Kremen Radio‐autographic studies of the [deepdyve.com]

(This article gives a thorough review of the literature regarding the etiology, epidemiology, and most common clinical presentations of chronic arsenic exposure. [clinicaladvisor.com]

(Etiology) Arsenical Keratosis is caused when skin cells (the keratinocytes that form the epidermis) are damaged from prolonged and frequently severe exposure to arsenic or arsenic-based compounds, over many decades Study research indicate that chronic [dovemed.com]

History Etiology and Pathogenesis Arsenic is present as either organic or inorganic compounds as well as in three potential oxidative states: metalloid, trivalent, and tetravalent. Trivalent arsenicals are the most common and hazardous to humans. [dermaamin.com]

No global epidemiologic studies have been performed, and no direct predilection has been found among persons of different races. [emedicine.medscape.com]

[…] mechanisms of one of the most toxic minerals in the world • Helps readers understand potential health effects of arsenic, using population studies, mammalian and invertebrate models, and pharmacokinetic and toxicokinetic models • Discusses outcomes, epidemiology [books.google.com]

Case Overview arsenical keratosis Member Rated 0 Patient case no. 2022 Date added 18 May 2003 Patient details Age --Undetermined-- Localisation Upper limbs / hands / palms Description Primary Lesions Papule / hyperpigmented Hyperkeratosis Pathophysiology [dermquest.com]

Pathophysiology: The inorganic form of arsenic is more toxic than organic arsenic. [visualdx.com]

Pathophysiology[edit] Arsenite impairs nucleotide excision repair,[6] and it may also affect gene expression by increasing or decreasing DNA methylation. [en.wikipedia.org]

Pathophysiology The exact mechanism for chromosomal damage has yet to be fully elucidated. [clinicaladvisor.com]

OBJECTIVE: For early detection and prevention of the arsenic-induced malignancies, the authors analyzed the clinical characteristics of arsenic-induced skin diseases. [koreamed.org]

The article reports treatment and preventative measures based on a review of the literature.) [clinicaladvisor.com]

Systemic Implications and Complications It’s important to treat squamous cell carcinomas early on to prevent the risk of metastasis. [dermatologyadvisor.com]

Medical treatment of PCOS is tailored to the patient's goals ... insulin levels Restoration of fertility Treatment of hirsutism or acne Restoration of regular menstruation, and prevention of endometrial hyperplasia and ... reasons for this is the lack [liquisearch.com]

Commencing early treatment can help prevent a progressive deterioration of Arsenical Keratosis and avoid complications. Several management measures are available and these include: Use of topical ointments, lotions, and creams. [dovemed.com]