Presentation
We present the case of a middle-aged Caucasian patient, who presented with fever and headache within a few hours of starting cetuximab therapy and was diagnosed with cetuximab-induced aseptic meningitis after a complete workup. [ncbi.nlm.nih.gov]
Entire Body System
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Pseudotumor
Pseudotumor cerebri was appropriately ruled-out. Summary of data altogether lead us suggest that isotretinoin triggered DIAM, possible due to a delayed hypersensitivity mechanism type III or IV. [ncbi.nlm.nih.gov]
Respiratoric
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Saddle Nose
She gradually developed neurosensory hearing loss, vertigo, and saddle nose while glucocorticosteroid therapy and combined cyclophosphamide could not control her headache. Ultimately, cyclosporin A was tried showing a good response. [ncbi.nlm.nih.gov]
Course
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Severe Clinical Course
Compromised BBB function correlated positively with length of hospitalization (p 0.007), indicative of a more severe clinical course. [ncbi.nlm.nih.gov]
Musculoskeletal
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Acroparesthesia
Neurological symptoms in Fabry disease mainly include stroke, acroparesthesia, cranial nerve palsies and autonomic dysfunction. We report on aseptic meningitis in Fabry patients. [ncbi.nlm.nih.gov]
Neurologic
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Flaccid Paralysis
Focal central nervous system infections, such as occur in the spinal cord with viral myelitis, are much less common and may be confused with noninfectious disorders that cause acute flaccid paralysis. [ncbi.nlm.nih.gov]
Workup
We present the case of a middle-aged Caucasian patient, who presented with fever and headache within a few hours of starting cetuximab therapy and was diagnosed with cetuximab-induced aseptic meningitis after a complete workup. [ncbi.nlm.nih.gov]
Other Pathologies
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Hepatic Necrosis
In younger patients, like babies, a meningeal inflammation can be noticed along with the possibility of hepatic necrosis and myocarditis. [en.wikipedia.org]
Treatment
DIAM has been recognized with various treatments including non-steroidal anti-inflammatory drugs, monoclonal antibodies and some antibiotics. [ncbi.nlm.nih.gov]
Prognosis
Clinicians need to consider syphilis in the differential diagnosis of macular or papular rashes with neurological conditions, particularly aseptic meningitis, as early diagnosis and treatment lead to a better prognosis. [ncbi.nlm.nih.gov]
Etiology
Further prospective studies are warranted to identify the correlations between the clinical characteristics and the etiologies of meningitis. 2015 Wiley Periodicals, Inc. KEYWORDS: aseptic meningitis; cerebrospinal fluid; etiology; signs and symptoms [ncbi.nlm.nih.gov]
Epidemiology
Abstract We reviewed the epidemiological and clinical characteristics of 927 aseptic meningitis patients in Shandong in 2014, and the phylogeny of predominant enterovirus (EV) types causing this disease was analyzed. [ncbi.nlm.nih.gov]
Prevention
[…] for Disease Control and Prevention, Jinan, People's Republic of China; Academy of Preventive Medicine, Shandong University, Jinan, People's Republic of China. 3 Shandong Provincial Key Laboratory of Infectious Disease Control and Prevention, Shandong [ncbi.nlm.nih.gov]