Presentation
In the present study, nine cases presented with the symptoms of fever, cough with chest pain and suffocation, while two cases presented with a mass in the chest and throat. Short-term symptoms progressed rapidly, with an average of 10–20 days. [spandidos-publications.com]
Conclusion Askin’s tumor is a rare tumor of childhood which usually presents with common respiratory symptoms. Pediatrician must be far sighted to suspect this rare entity with such common presentations. [hindawi.com]
The common presentation in patients with askin's tumor is chest pain, respiratory distress or a chest wall mass [3]. Rarely, It may present as pathological fracture or metastasis related symptoms [5]. [panafrican-med-journal.com]
A history of tubercular contact was present in her mother 4 years back. [ncbi.nlm.nih.gov]
Visit our Pediatric Community CASE SUMMARY A previously healthy 9-year-old male presented with a several-week history of progressive shortness of breath. [appliedradiology.com]
Workup
It requires immunohistochemical workup supported by imaging investigations. Treatment is not yet codified. However, surgery is predominant. The Prognosis is poor. We describe a case of a 18 year old male without metastatic disease at presentation. [panafrican-med-journal.com]
Treatment
Therefore, the survival ratio was significantly improved in the combined treatment group compared with that of the single treatment group (P<0.05). [spandidos-publications.com]
Treatment of Askin's tumor should be multimodal, requiring discussion in multidisciplinary tumor working groups. The treatment includes chemotherapy, radiotherapy and surgery. [panafrican-med-journal.com]
So it is of utmost importance to make an early diagnosis and proper referral/treatment in such cases. We highlighted diagnostic challenge, treatment, and favorable outcome of a case that presented to us. [ncbi.nlm.nih.gov]
Lewis et al., “Results of the EICESS-92 study: two randomized trials of Ewing's sarcoma treatment-cyclophosphamide compared with ifosfamide in standard risk patients and assessment of benefit of etoposide added to standard treatment in high risk patients [hindawi.com]
Patients and methods Table 1Patients with Askin tumor: Primary site and treatment Case (age [y], sex) Chief symptom Primary site Treatment for primary tumor 1 (32, F) Abnormal shadow on chest film Right posterior pleura Chest wall resection with 4 ribs [jtcvs.org]
Prognosis
We believe that this prognosis would have been better if the diagnosis was made earlier, allowing surgical excision. [panafrican-med-journal.com]
However, recent genetic research has led to the conclusion that it is essentially the same as Ewing sarcoma, and now is part of the collective term Ewing sarcoma family of tumors, sharing similar demographics, imaging findings and prognosis 2,3. [radiopaedia.org]
Univariate analysis revealed that poor prognosis was associated with a tumor diameter >5 cm, LDH levels >240 U/l and late stage (stage III or IV) tumors. [spandidos-publications.com]
It would require a high index of suspicion on behalf of the general pediatrician for the early recognition of this tumor so that chances of better outcome and prognosis shall be there. [hindawi.com]
Crossref PubMed Scopus (500) Google Scholar Askin tumors typically involve the periosteum, soft tissues, and extrapulmonary tissue of the thoracic wall, and the prognosis is very poor. 2 Contesso G Llombert-Bosch A Terrier P Peydro-Olaya A Henry-Amar [jtcvs.org]
Etiology
With this case report we hope to highlight the importance of keeping in mind askin tumors as one etiologic possibility of chest wall tumor. Early diagnosis could improve the prognosis. [panafrican-med-journal.com]