Table 2 presents the analysis of these data. [htct.com.br]

The present study deals with the successful screening of potent microorganisms producing l-asparaginase. 47 microorganisms were screened including bacteria, fungi, and yeasts. [ncbi.nlm.nih.gov]

• Thyroid Nodule

  The effect of L-asparaginase on the thyroid gland has not been well documented. We report the first two cases of hyperthyroidism associated with thyroid nodule following L-asparaginase therapy for acute lymphoblastic leukemia (ALL). [ncbi.nlm.nih.gov]

• Esotropia

  Ocular motor examination revealed esotropia with a right abduction deficit, consistent with a sixth nerve palsy, and funduscopy revealed bilateral optic disc edema. [ncbi.nlm.nih.gov]

• Focal Seizure

  Intracranial hemorrhage and focal seizures secondary to use of l-asparaginase during induction therapy of acute lymphocytic leukemia. J Pediatr. 1980; 97:829-33. [PubMed 6933231] 101. Priest JR, Ramsay NKC, Steinherz PG et al. [web.archive.org]

• Glutamine Increased

  The substitution of Ser-254 with either an asparagine or a glutamine increases the l-asparagine specificity but only when combined with the E63Q mutation. [ncbi.nlm.nih.gov]

• Diffuse Encephalopathy

  encephalopathy or reversible posterior leukoencephalopathy syndrome. [eviq.org.au]

Treatment Adult Acute Lymphocytic Leukemia 3 4 Completed Treatment Lymphoma, Lymphoblastic 1 4 Recruiting Treatment Acute Lymphobkastic Leukemia 1 4 Recruiting Treatment Acute Lymphoblastic Leukaemias (ALL) 1 4 Recruiting Treatment Peripheral T Cell [drugbank.ca]

This will render the drug ineffective and may result in loss of treatment effect. [eviq.org.au]

Acute Lymphobkastic Leukemia 1 4 Completed Treatment Acute Lymphoblastic Leukemia (ALL) 5 4 Completed Treatment Leukemia, Lymphocytic, Acute, Adult 4 4 Completed Treatment Lymphoma, Lymphoblastic 1 4 Recruiting Treatment Peripheral T Cell Lymphoma (PTCL [go.drugbank.com]

Therefore, little is known about this subtype of lymphoma, including its treatment and prognosis. A 65-year-old man was diagnosed with T-cell lymphoma with abundant CD20 expression. [ncbi.nlm.nih.gov]

ALL in children has a much better prognosis than in adults, with over 90% of children going into remission and an 80% cure rate with chemotherapy. [encyclopedia.com]

Reversible posterior leukoencephalopathy syndrome (RPLS) is being increasingly described with various etiologies even in the absence of hypertension. [ncbi.nlm.nih.gov]

Notably, more than half of the CVTs were diagnosed prior the administration of asparaginase which accentuates the role of other risk factors on the pathophysiology of CVT compared to truncal or central venous line (CVL) VTs in adult ALL patients. © 2017 [ncbi.nlm.nih.gov]

We review the previously reported cases and discuss the clinical presentation, pathophysiology, and suggested treatment of this syndrome. © 1988 by the American Academy of Neurology AAN Members: Sign in with your AAN member credentials (e-mail or 6-digit [n.neurology.org]

Effective strategies to prevent and treat AD remain elusive despite major efforts to understand its basic biology and clinical pathophysiology. Significant investments in therapeutic ... [doi.org]

Timing of reaction (after the second or third exposure most common in true hypersensitivity), symptoms (angioedema, pathognomonic for true hypersensitivity), and therapeutic drug monitoring are all items that may give clues as to the underlying pathophysiology [frontiersin.org]

Prevention Avoidance of alcohol is a key preventative measure. [eviq.org.au]

Octreotide 100 μg subcutaneously 3 times/day, utilized as a chemoprotectant, was found to prevent pancreatitis recurrence. [ncbi.nlm.nih.gov]