Presentation
To guide provision of optimal clinical care and therapeutic intervention, routine assessment of ASD is recommended in youth presenting for gender dysphoria. [ncbi.nlm.nih.gov]
Musculoskeletal
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Motor Restlessness
Tuisku K, Tani P, Nieminen-von Wendt T, von Wendt L, Holi M, Porkka-Heiskanen T, Lauerma H, Lindberg N, Appelberg B, Wahlbeck K: Lower-limb motor restlessness in Asperger’s disorder, measured using actometry. Psychol Res, in press. [oadoi.org]
Eyes
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Eye Movements Abnormal
Various eye movement abnormalities in AS have been reported in literature such as increased errors and latencies on the antisaccadic task implicating dysfunction of the prefrontal cortex, impairment of the pursuit especially for targets presented in the [ncbi.nlm.nih.gov]
Psychiatrical
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Indecisiveness
Excessively high performance standards, perfectionism, a disproportionate inclination to self-criticism, and agonizing indecisiveness when the customary rules and values do not apply are all features of compulsive personality disorder that typically are [doi.org]
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Perceptual Distortion
In contrast, schizotypal PD is typified by seemingly eccentric social-contact behavior, with apparently paranoid perceptual distortion and bizarre convictions (“magical thinking”). [doi.org]
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Persecutory Delusion
& KANEY, S. ( 1994 ) ‘The Self, Attributional Processes, and Abnormal Beliefs: Towards a Model of Persecutory Delusions’, Behaviour Research and Therapy 32: 331 - 341. Google Scholar Crossref Medline ISI BOWLER, D. [aut.sagepub.com]
Neurologic
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Amnesia
M. ( 1997 ) ‘Asperger’s Syndrome and Memory: Similarity to Autism but Not Amnesia’, Neuropsychologia 35: 65 - 70. Google Scholar Crossref Medline ISI BREWIN, C. R. ( 1985 ) ‘Depression and Causal Attributions: What Is Their Relation?’ [aut.sagepub.com]
Asperger's syndrome and memory: similarity to autism but not amnesia. Neuropsychologia. Jan 1997;35(1):65-70. [Medline]. Bowman EP. Asperger's syndrome and autism: the case for a connection. Br J Psychiatry. Mar 1988;152:377-82. [Medline]. [web.archive.org]
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Nystagmus
There are no reports in the literature of association between idiopathic infantile nystagmus (IIN) and AS. We report 2 cases of Asperger syndrome associated with idiopathic infantile nystagmus. [ncbi.nlm.nih.gov]
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Dysmetria
As the cerebellum controls sensorimotor coordination and lesions here typically cause hypotonia, dysmetria and dyscoordination, we performed a series of quantitative tests aimed at investigating cerebellar function in Asperger individuals. [dx.doi.org]
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Postural Instability
In comparison to control subjects, Asperger subject’s demonstrated: (i) decreased pointing accuracy and rate, (ii) increased postural instability, and (iii) decreased timing accuracy. [dx.doi.org]
Workup
(See Workup.) None of these studies are required for diagnosis, but the results can help guide treatment planning. If Asperger syndrome is diagnosed, social skills training and other psychological interventions may be provided. [emedicine.medscape.com]
Treatment
Differences in comparison to the control group had decreased after treatment. The treatment was acceptable to families and subject adherence was high. [ncbi.nlm.nih.gov]
Treatment There is no cure for AS, nor is there one single treatment for autism spectrum disorders. But there are ways to help reduce the symptoms of autism and to help a child learn. [web.archive.org]
Prognosis
The results underscore the importance of analysing the cognitive profile both at diagnosis and after several years, so as to be able to formulate a realistic prognosis. [ncbi.nlm.nih.gov]
Prognosis with aspergers Persons with Asperger syndrome appear to have normal lifespans, but have an increased prevalence of comorbid psychiatric conditions such as depression, mood disorders, and obsessive-compulsive disorder. [autism-help.org]
Videos Further Reading Asperger Syndrome Causes Asperger Syndrome Mechanism Asperger Syndrome Screening Asperger Syndrome Treatment Asperger Syndrome Prognosis [news-medical.net]
Those with supportive families who are knowledgeable about the condition tend to have a better prognosis. [emedicinehealth.com]
Etiology
The precise etiology is still unknown, but a multifactorial origin with genetic, neurobiological, and psychosocial components appears probable. [ncbi.nlm.nih.gov]
Epidemiology
Severe impairments of social interaction and associated abnormalities in children: Epidemiology and classification. Journal of Autism and Developmental Disorders, 9 (1), 11–29. [doi.org]
Existing research is reviewed within the areas of epidemiology, medical/neurobiologic factors, genetics, and outcome, and future directions for research are recommended. [ncbi.nlm.nih.gov]
The epidemiology of Asperger Syndrome. A total population study. Journal of Child Psychology and Psychiatry, 34, 1327–1350. PubMed CrossRef Google Scholar Everall, I. P., & LeCouteur, A. (1990). [oadoi.org]
Pathophysiology
Comorbid conditions may be markers for underlying pathophysiology and suggest a more varied treatment approach. [ncbi.nlm.nih.gov]
Likewise, relatively few studies of genetic and environmental factors in the pathophysiology of AS have involved large and well-characterized samples. [dx.doi.org]
Nevertheless, there is likely some role of serotonin in the pathophysiology of AS. [web.archive.org]
Prevention
These findings highlight a need for more specialized services to help prevent future attempts and to support this vulnerable group. [ncbi.nlm.nih.gov]
Can it be prevented? AS cannot be prevented because we do not know what causes it. When should I call the doctor? Call your doctor if your child shows behaviors of AS from the signs and symptoms list above. [virtualpediatrichospital.org]
Coping With Asperger's Your Asperger Child: Preventing Problems Rather Than Reacting to Them Your Asperger Child: Preventing Problems Rather Than Reacting to ThemSooner is better than later. [life.familyeducation.com]
(I statement) The US Preventive Services Task Force (USPSTF) makes recommendations about the effectiveness of specific preventive care services for patients without obvious related signs or symptoms. [doi.org]