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Asperger Syndrome

Asperger's Syndrome


Presentation

  • To guide provision of optimal clinical care and therapeutic intervention, routine assessment of ASD is recommended in youth presenting for gender dysphoria.[ncbi.nlm.nih.gov]
  • Poster presented at the conference "Evidence Based Assessment and Intervention in Autism and Comorbid Disorders".[scribd.com]
Noncompliance
  • The intervention involves graduated exposure of a child to increasingly more challenging requests at a slow enough rate to ensure that noncompliance rarely occurs, providing parents with many opportunities to reinforce cooperative responses and rendering[ncbi.nlm.nih.gov]
  • . & LERMAN, D.C. ( 1999 ) ‘A Preliminary Comparison of Guided Compliance and High-Probability Instructional Sequences as Treatment for Noncompliance in Children with Developmental Disabilities’, Research in Developmental Disabilities 20: 183 - 195.[doi.org]
  • […] the pragmatics and give-and-take of normal conversation.Of the many studies on behavior-based early intervention programs, most are case reports of up to five participants and typically examine a few problem behaviors such as self-injury, aggression, noncompliance[en.wikipedia.org]
Nocturnal Awakening
  • There is no evidence that these motor skills problems differentiate AS from other high-functioning ASDs.Children with AS are more likely to have sleep problems, including difficulty in falling asleep, frequent nocturnal awakenings, and early morning awakenings[en.wikipedia.org]
Motor Restlessness
  • Tuisku K, Tani P, Nieminen-von Wendt T, von Wendt L, Holi M, Porkka-Heiskanen T, Lauerma H, Lindberg N, Appelberg B, Wahlbeck K: Lower-limb motor restlessness in Asperger’s disorder, measured using actometry. Psychol Res, in press.[oadoi.org]
Indecisiveness
  • Excessively high performance standards, perfectionism, a disproportionate inclination to self-criticism, and agonizing indecisiveness when the customary rules and values do not apply are all features of compulsive personality disorder that typically are[doi.org]
Perceptual Distortion
  • In contrast, schizotypal PD is typified by seemingly eccentric social-contact behavior, with apparently paranoid perceptual distortion and bizarre convictions (“magical thinking”).[doi.org]
Persecutory Delusion
  • . & KANEY, S. ( 1994 ) ‘The Self, Attributional Processes, and Abnormal Beliefs: Towards a Model of Persecutory Delusions’, Behaviour Research and Therapy 32: 331 - 341. Google Scholar Crossref Medline ISI BOWLER, D.[aut.sagepub.com]
Amnesia
  • M. ( 1997 ) ‘Asperger’s Syndrome and Memory: Similarity to Autism but Not Amnesia’, Neuropsychologia 35: 65 - 70. Google Scholar Crossref Medline ISI BREWIN, C. R. ( 1985 ) ‘Depression and Causal Attributions: What Is Their Relation?’[aut.sagepub.com]
  • Asperger's syndrome and memory: similarity to autism but not amnesia. Neuropsychologia . Jan 1997;35(1):65-70. [Medline]. Bowman EP. Asperger's syndrome and autism: the case for a connection. Br J Psychiatry . Mar 1988;152:377-82. [Medline].[web.archive.org]
Dystonia
  • Weight gain and fatigue are commonly reported side effects of risperidone, which may also lead to increased risk for extrapyramidal symptoms such as restlessness and dystonia and increased serum prolactin levels.[en.wikipedia.org]
  • Extrapyramidal side effects Extrapyramidal side effects are adverse, movement‐related symptoms, which include drug‐induced parkinsonism, dystonia, akathisia and tardive dyskinesia.[doi.org]
Nystagmus
  • There are no reports in the literature of association between idiopathic infantile nystagmus (IIN) and AS. We report 2 cases of Asperger syndrome associated with idiopathic infantile nystagmus.[ncbi.nlm.nih.gov]
Dysmetria
  • As the cerebellum controls sensorimotor coordination and lesions here typically cause hypotonia, dysmetria and dyscoordination, we performed a series of quantitative tests aimed at investigating cerebellar function in Asperger individuals.[dx.doi.org]
Postural Instability
  • In comparison to control subjects, Asperger subject’s demonstrated: (i) decreased pointing accuracy and rate, (ii) increased postural instability, and (iii) decreased timing accuracy.[dx.doi.org]

Workup

  • (See Workup.) None of these studies are required for diagnosis, but the results can help guide treatment planning. If Asperger syndrome is diagnosed, social skills training and other psychological interventions may be provided.[emedicine.com]

Treatment

  • Differences in comparison to the control group had decreased after treatment. The treatment was acceptable to families and subject adherence was high.[ncbi.nlm.nih.gov]
  • Treatment There is no cure for AS, nor is there one single treatment for autism spectrum disorders. But there are ways to help reduce the symptoms of autism and to help a child learn.[web.archive.org]

Prognosis

  • The results underscore the importance of analysing the cognitive profile both at diagnosis and after several years, so as to be able to formulate a realistic prognosis.[ncbi.nlm.nih.gov]
  • Prognosis with aspergers Persons with Asperger syndrome appear to have normal lifespans, but have an increased prevalence of comorbid psychiatric conditions such as depression, mood disorders, and obsessive-compulsive disorder.[autism-help.org]
  • Videos Further Reading Asperger Syndrome Causes Asperger Syndrome Mechanism Asperger Syndrome Screening Asperger Syndrome Treatment Asperger Syndrome Prognosis[news-medical.net]
  • Those with supportive families who are knowledgeable about the condition tend to have a better prognosis.[emedicinehealth.com]

Etiology

  • The precise etiology is still unknown, but a multifactorial origin with genetic, neurobiological, and psychosocial components appears probable.[ncbi.nlm.nih.gov]

Epidemiology

  • The clinical features, course, aetiology, epidemiology, differential diagnosis and management of Asperger's syndrome are described.[ncbi.nlm.nih.gov]
  • Severe impairments of social interaction and associated abnormalities in children: Epidemiology and classification. Journal of Autism and Developmental Disorders, 9 (1), 11–29.[doi.org]
Sex distribution
Age distribution

Pathophysiology

  • Comorbid conditions may be markers for underlying pathophysiology and suggest a more varied treatment approach.[ncbi.nlm.nih.gov]
  • Likewise, relatively few studies of genetic and environmental factors in the pathophysiology of AS have involved large and well-characterized samples.[doi.org]
  • Nevertheless, there is likely some role of serotonin in the pathophysiology of AS.[web.archive.org]

Prevention

  • These findings highlight a need for more specialized services to help prevent future attempts and to support this vulnerable group.[ncbi.nlm.nih.gov]
  • Can it be prevented? AS cannot be prevented because we do not know what causes it. When should I call the doctor? Call your doctor if your child shows behaviors of AS from the signs and symptoms list above.[virtualpediatrichospital.org]
  • Coping With Asperger's Your Asperger Child: Preventing Problems Rather Than Reacting to Them Your Asperger Child: Preventing Problems Rather Than Reacting to ThemSooner is better than later.[life.familyeducation.com]
  • (I statement) The US Preventive Services Task Force (USPSTF) makes recommendations about the effectiveness of specific preventive care services for patients without obvious related signs or symptoms.[doi.org]

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