Presentation
To guide provision of optimal clinical care and therapeutic intervention, routine assessment of ASD is recommended in youth presenting for gender dysphoria. [ncbi.nlm.nih.gov]
Psychiatrical
- Perceptual Distortion
In contrast, schizotypal PD is typified by seemingly eccentric social-contact behavior, with apparently paranoid perceptual distortion and bizarre convictions (“magical thinking”). [doi.org]
- Persecutory Delusion
P. ( 1996b ) ‘Self Discrepancies and Persecutory Delusions: Evidence for a Defensive Model of Paranoid Ideation’, Journal of Abnormal Psychology 105: 106 - 114. Google Scholar | Crossref | Medline | ISI KINDERMAN, P. & BENTALL, R. [aut.sagepub.com]
Neurologic
- Amnesia
M. ( 1997 ) ‘Asperger’s Syndrome and Memory: Similarity to Autism but Not Amnesia’, Neuropsychologia 35: 65 - 70. Google Scholar | Crossref | Medline | ISI BREWIN, C. R. ( 1985 ) ‘Depression and Causal Attributions: What Is Their Relation?’ [aut.sagepub.com]
Asperger's syndrome and memory: similarity to autism but not amnesia. Neuropsychologia. Jan 1997;35(1):65-70. [Medline]. Bowman EP. Asperger's syndrome and autism: the case for a connection. Br J Psychiatry. Mar 1988;152:377-82. [Medline]. [web.archive.org]
- Nystagmus
There are no reports in the literature of association between idiopathic infantile nystagmus (IIN) and AS. We report 2 cases of Asperger syndrome associated with idiopathic infantile nystagmus. [ncbi.nlm.nih.gov]
- Dysmetria
As the cerebellum controls sensorimotor coordination and lesions here typically cause hypotonia, dysmetria and dyscoordination, we performed a series of quantitative tests aimed at investigating cerebellar function in Asperger individuals. [dx.doi.org]
- Postural Instability
In comparison to control subjects, Asperger subject’s demonstrated: (i) decreased pointing accuracy and rate, (ii) increased postural instability, and (iii) decreased timing accuracy. [dx.doi.org]
Workup
(See Workup.) None of these studies are required for diagnosis, but the results can help guide treatment planning. If Asperger syndrome is diagnosed, social skills training and other psychological interventions may be provided. [emedicine.com]
MR
- Brain MRI Abnormal
Tomoko Miyajima, Nobusuke Kimura, Tomohiro Kumada, Nozomi Oda, Hideki Shimomura and Tatsuya Fujii, Epilepsy in pervasive developmental disorder without brain MRI abnormalities, Brain and Development, 33, 6, (504), (2011). [doi.org]
Treatment
The etiopathogenesis and treatment of Asperger's syndrome in adulthood should be further investigated. [ncbi.nlm.nih.gov]
The diagnosis of Asperger syndrome is increasingly common, and it is timely to review its phenomenology and treatment. [dx.doi.org]
Prognosis
The results underscore the importance of analysing the cognitive profile both at diagnosis and after several years, so as to be able to formulate a realistic prognosis. [ncbi.nlm.nih.gov]
Prognosis with aspergers Persons with Asperger syndrome appear to have normal lifespans, but have an increased prevalence of comorbid psychiatric conditions such as depression, mood disorders, and obsessive-compulsive disorder. [autism-help.org]
Videos Further Reading Asperger Syndrome Causes Asperger Syndrome Mechanism Asperger Syndrome Screening Asperger Syndrome Treatment Asperger Syndrome Prognosis [news-medical.net]
This model, if replicated in a prospective, population-based sample that is controlled for treatment modalities, will enhance our ability to offer a prognosis for the child with ASD and will provide a benchmark against which to judge the putative benefits [doi.org]
Google Scholar | Crossref | Medline | ISI Naseef, R, Freedman, B ( 2012 ) A diagnosis of autism is not a prognosis of divorce. Autism Advocate. Fall : 9 – 12. Google Scholar [aut.sagepub.com]
Etiology
The precise etiology is still unknown, but a multifactorial origin with genetic, neurobiological, and psychosocial components appears probable. [ncbi.nlm.nih.gov]
The aim of this review is to present a description of AS, an up to date synopsis of the literature pertaining to its etiology, co-morbidity and intervention options, and a discussion of current nosological controversies. ... weniger Klassifikation Medizin [ssoar.info]
Epidemiology
Severe impairments of social interaction and associated abnormalities in children: Epidemiology and classification. Journal of Autism and Developmental Disorders, 9 (1), 11–29. [doi.org]
Existing research is reviewed within the areas of epidemiology, medical/neurobiologic factors, genetics, and outcome, and future directions for research are recommended. [ncbi.nlm.nih.gov]
Paediatric and Perinatal Epidemiology, 22, 6, (562-568), (2008). Kristen S.L. Lam, James W. [dx.doi.org]
Pathophysiology
Comorbid conditions may be markers for underlying pathophysiology and suggest a more varied treatment approach. [ncbi.nlm.nih.gov]
Nevertheless, there is likely some role of serotonin in the pathophysiology of AS. [web.archive.org]
[…] neurodevelopmental, mental, or behavioral disorder With catatonia [2, 3, 4, 58] By the current DSM-5 criteria, individuals previously diagnosed with Asperger syndrome would be diagnosed as having ASD without language or intellectual impairment. [1] Pathophysiology [emedicine.com]
Prevention
Can it be prevented? AS cannot be prevented because we do not know what causes it. When should I call the doctor? Call your doctor if your child shows behaviors of AS from the signs and symptoms list above. [virtualpediatrichospital.org]
Misdiagnosing Asperger syndrome creates severe problems by preventing effective therapy. [ncbi.nlm.nih.gov]
(I statement) The US Preventive Services Task Force (USPSTF) makes recommendations about the effectiveness of specific preventive care services for patients without obvious related signs or symptoms. [doi.org]
It's possible that an infant's sudden, rapid head growth may be an early warning signal, which could help in early diagnosis and treatment or possible prevention of ASD. [web.archive.org]