Presentation
It presents as a chronic sinusitis with headache, nasal discharge and obstruction. [aspergillus.org.uk]
The authors present a case of a patient presenting with painful tearing which elicited further evaluation with CT imaging. This revealed a maxillary sinus fungus ball as the cause for the patient's tearing. [ncbi.nlm.nih.gov]
The authors present a case of a patient presenting with painful tearing which elicited further evaluation with CT imaging. This revealed a maxillary sinus fungus ball as the cause for the patient’s tearing. [ingentaconnect.com]
Entire Body System
- Congestive Heart Failure
Further history included moderate pulmonary hypertension, New York Heart Association Class III 2 congestive heart failure and an episode of mycobacterium avium complex that was successfully treated 3 years prior to the initial visit with us. [journal.copdfoundation.org]
Respiratoric
- Cough
The initial manifestations of the disease on admission included cough, dyspnea, hemoptysis, pulmonary infiltrate, and renal failure. [ncbi.nlm.nih.gov]
They can experience unintended weight loss, a chronic cough that produces mucus, the coughing up of blood, fatigue, and shortness of breath. Less often, fever or night sweats can occur. [rarediseases.org]
[…] breath Kidney or liver failure Shock Bloody cough or massive bleeding from the lungs Allergic bronchopulmonary aspergillosis may cause: Coughing accompanied by mucus or blood Wheezing or worsening of asthma Fever Increased mucus or sputum secretions [my.clevelandclinic.org]
– you may cough up blood or lumps of mucus wheezing (a whistling sound when breathing) a high temperature of 38C or above weight loss If you already have a lung condition, your existing symptoms may get worse. a cough for more than 3 weeks a lung condition [nhs.uk]
Sometimes bothersome cough. Unpleasant infection of various internal organs. Fever. [medical-enc.com]
- Hemoptysis
[…] those with hemoptysis due to other causes. [jcm.asm.org]
The initial manifestations of the disease on admission included cough, dyspnea, hemoptysis, pulmonary infiltrate, and renal failure. [ncbi.nlm.nih.gov]
Occasionally due to surrounding reactive vascular granulation tissue, hemoptysis may be present. Occasionally, erosion into a bronchial artery may lead to life-threatening hemoptysis 1. [radiopaedia.org]
Amongst symptomatic, the most common symptoms include cough and hemoptysis. [thoracicmedicine.org]
In such cases surgical resection is indicated if significant hemoptysis occurs. [aacijournal.biomedcentral.com]
- Chronic Cough
They can experience unintended weight loss, a chronic cough that produces mucus, the coughing up of blood, fatigue, and shortness of breath. Less often, fever or night sweats can occur. [rarediseases.org]
A case report • A 71-year-old Chinese male was admitted with complaint of chronic cough and malaise for two months. He had been in Tucson, Arizona, USA, visiting for four months right before the symptoms occurred. [slideshare.net]
- Pulmonary Disorder
Chandler. (2008) The Pathology of Pulmonary Disorders Due to Aspergillus spp. Archives of Pathology & Laboratory Medicine 132 :11, 1713-1714. Online publication date: 1-Oct-2009. [archivesofpathology.org]
- Productive Cough
Patients will usually have very minor symptoms, such as a mild cough, and little evidence of systemic inflammation. When symptoms progress, patients may present with weight loss, productive cough, fatigue and shortness of breath. [journal.copdfoundation.org]
Musculoskeletal
- Osteoporosis
Radiographs revealed fungal involvement of the heads of the tibia and fibula, cavitation in femur, patella periosteal bone deposition and diffuse osteoporosis. [medicaljournals.se]
Workup
Certain associated atypical symptoms may warrant further workup. The authors present a case of a patient presenting with painful tearing which elicited further evaluation with CT imaging. [ncbi.nlm.nih.gov]
Diagnosis is often made as a result of an incidental finding on a chest X-ray or CT scan that may be performed as part of the workup for another unrelated condition. [en.wikipedia.org]
Microbiology
- Aspergillus Fumigatus in the Sputum
Clinical and immunologic significance of Aspergillus fumigatus in the sputum. [ncbi.nlm.nih.gov]
Treatment
This treatment resulted in remission of the vasculitis. [ncbi.nlm.nih.gov]
After endoscopic treatment, the right maxillary sinus was irrigated using amphotericin B for 2 weeks and then treated by iodine with gentamicin and ketoconazole for 6 weeks. At 1 month after endoscopic treatment, the mycetoma had disappeared. [surgicalcasereports.springeropen.com]
Aspergillus Fumigatus Fungus Ball in the Transplanted Lung after Single Lung Transplantation: Treatment with Cavernostomy and Withdrawal of the Mycetoma. Clin Surg. 2017; 2: 1837. [clinicsinsurgery.com]
Fungal Sinusitis Treatment The treatment of choice for all types of fungal sinusitis is surgical. Medical treatment depends on the type of infection and the presence of invasion. [earnosethroat.com.au]
Prognosis
[…] which is a hypersensitive asthmatic reaction to Aspergillus antigens invasive aspergillosis, which is an acute infection that produces septicemia, thrombosis, and infarction of virtually any organ, especially the heart, lungs, brain, and kidneys Varied prognosis [quizlet.com]
Prognosis CNPA has a significant mortality of up to 40%, even if promptly recognised and treated. It is easy to miss and, in such cases, carries a worse prognosis. [patient.info]
Treatment and prognosis An asymptomatic aspergilloma does not necessarily require treatment, and the cavity is essentially isolated from any systemic administration of antifungal 3. [radiopaedia.org]
Voriconazole (VFEND) With proper treatment, the prognosis is general good as the disease responds well to both antibiotic and antifungal medications. [lymphedemapeople.com]
Treatment and prognosis The treatment is chosen only after distinguishing if the disease is an actinomycetoma or a eumycetoma. [afwgonline.com]
Etiology
The etiologic agents range from bacteria to fungi existing free in nature as soil or plant saprophytes gaining entrance into the tissues through abrasion or implantation. Actinomycetoma is caused by aerobic species of actinomycetes. [aspergillus.org.uk]
Root canal treated teeth with overextension of the root canal sealer or solid materials such as gutta-percha or silver cones into the sinus might be the main etiological factor for aspergillosis of the maxillary sinus in healthy patients. [ncbi.nlm.nih.gov]
Complete patients' characteristics and etiological agents are reported in Table 1. In 2 cases, the infection was acquired in India, in 2 in Ethiopia, an in 1 case each in Senegal, Tanzania, Honduras, and Italy. [karger.com]
Pseudallescheria boydii is the most common etiologic agent of eumycetoma in the United States. Madurella mycetomatis accounts for most cases worldwide. Madurella grisea is a common etiologic agent in South America. [emedicine.medscape.com]
Epidemiology
Eumycetoma and actinomycetoma–an update on causative agents, epidemiology, pathogenesis, diagnostics and therapy. J Eur Acad Dermatol Venereol 2015;29:1873-1883. van de Sande WW. [afwgonline.com]
The Conference Theme is: The Holistic management of Mycetoma The following issues will be discussed during the conference: Mycetoma Epidemiology, Control & Eradication Novel Organisms Causing Mycetoma Clinical Presentation of Mycetoma New Diagnostic Tools [aspergillus.org.uk]
The injuries were classified in five categories that pointed injuries such as pricking that had special importance in the epidemiology of mycetoma and the other included cuts, operated injuries, scratch and war injuries. [scialert.net]
Aspergilloma Epidemiology Aspergilloma has a variable prevalence depending on the amount of cavitating lung disease affecting a population. [patient.info]
Pathophysiology
Stefano Veraldi1, Anna Grancini2, Luigia Venegoni1, Valentina Merlo1, Elena Guanziroli1, Claudia Menicanti1, Gianluca Nazzaro1 and Annamaria Tortorano3 1Department of Pathophysiology and Transplantation, Università degli Studi di Milano, IRCCS Foundation [medicaljournals.se]
[…] accumulation of fungal hyphae Essential features Dense fungal growth with no tissue invasion Fruiting heads (sexual reproduction) may be seen Terminology Fungal ball, mycetoma, chronic noninvasive fungal sinusitis Sites Maxilla is most commonly affected Pathophysiology [pathologyoutlines.com]
Author Contacts Gianluca Nazzaro, MD Department of Pathophysiology and Transplantation Università degli Studi di Milano, I.R.C.C.S. [karger.com]
Pathophysiology The foot is the most common site of infection, and 70% of all mycetomas affect the foot. [emedicine.medscape.com]
Pathophysiology In a healthy, immunocompetent individual, macrophages and neutrophils normally defend against the inhaled fungus. [patient.info]
Prevention
[…] of HIV HIV Transmission and Prevention in Specific Populations Systematic Review of HIV Behavioral Prevention Research in African Americans Lynae A. [hivinsite.ucsf.edu]
These problems are addressed and measures of prevention such as smoking cessation are included. [books.google.com]
Risk & Prevention Mycetoma is a health problem in equatorial regions of Africa, Latin America, and Asia known as the “mycetoma belt.” [cdc.gov]
Prevention The best prevention of aspergillosis is a healthy way of life that is capable of normal immune system. [medical-enc.com]
Centers for Disease Control and Prevention. Disease condition caused by species of aspergillus and marked by inflammatory granulomatous lesions in the skin, ear, orbit, nasal sinuses, lungs, and sometimes in the bones and meninges. [icd10data.com]