Immunohistological and ultrastructural features of this tumor are presented. The discussion focuses on the biology, natural history, and management of this unusual neoplasm. [ncbi.nlm.nih.gov]

• Plethora

  Unlike conventional low-grade tumors, high-grade tumors associate a plethora of factors when they metastasize to other areas of the body. [en.wikipedia.org]

• Episodic Vomiting

  A 12-year-old girl child presented with episodes of generalized tonic-clonic seizures for 6 months and headache and episodic vomiting for 2 months. Neurological examination did not reveal any significant abnormality. [pediatricneurosciences.com]

• Long Arm

  Molecular analysis using 17 microsatellite markers on chromosomes 9, 10, 11, 17, 19, and 22 showed loss of heterozygosity at the D19S412 locus on the long arm of chromsome 19. [ncbi.nlm.nih.gov]

• Suggestibility

  Hemorrhage, which suggested the presence of a vascular lesion in this patient, has not been previously described as a feature of this neoplasm. [ncbi.nlm.nih.gov]

• Papilledema

  Her neurological examination showed right 6 th nerve paresis with papilledema. Brain magnetic resonance imaging (MRI) revealed well-demarcated, peripherally enhancing solid cystic mass of 6 cm in right parietal lobe with mass effect. [dx.doi.org]

  The neurological examination showed right 6 th nerve paresis with papilledema. [ncbi.nlm.nih.gov]

  Her neurological examination revealed 6th nerve palsy and papilledema. [medresearch.in]

  The neurological examination showed right sixth nerve paresis with bilateral papilledema. [cancerjournal.net]

  Bilateral papilledema was detected on fundoscopy. Routine blood and biochemical investigations were within normal limits. [pediatricneurosciences.com]

• Throbbing Headache

  headache or nausea for the patient. [en.wikipedia.org]

• Nystagmus

  Horizontal nystagmus and other involuntary eye disorders can occur. Frequent reports show that adolescents and adults with grade III and IV astroblastoma fall frequently before they even reach a doctor's office. [en.wikipedia.org]

• Motor Symptoms

  Case Description: We present the case of a 9-year-old girl who presented with headache, motor symptoms, and seizures few days before she was admitted to our institution. [surgicalneurologyint.com]

Full pathologic workup later revealed the patient had two distinct tumors occurring simultaneously, anaplastic astrocytoma and astroblastoma. [ncbi.nlm.nih.gov]

Afterwards, metastatic workup of the patient including x-ray chest and ultrasound abdomen and pelvis did not revealed any spread of the disease. [synapse.koreamed.org]

• Karyotype Abnormal

  Further cytogenetic studies will also help to identify if there are consistent karyotypic abnormalities in these enigmatic tumors. [ncbi.nlm.nih.gov]

• Foam Cell

  Foam cells were frequently infiltrated around blood vessels and among tumor cells. In some areas, a solid growth pattern of plump tumor cells with abundant inclusion-like eosinophilic cytoplasm showing rhabdoid appearance was observed. [ncbi.nlm.nih.gov]

Surgical resection is the standard initial treatment for astroblastomas. Still, some astroblastomas that have been completely resected recur. The optimal treatment for these lesions is unclear. [ncbi.nlm.nih.gov]

Chemotherapy is the preferred secondary treatment after resection. The treatment kills astroblastoma cells left behind after surgery and induces a non-dividing, benign state for remaining tumor cells. [en.wikipedia.org]

Prognosis of astroblastoma depends on the extent of resection and histology. The proliferative index may be a useful tool to define prognosis. [ncbi.nlm.nih.gov]

Hemorrhagic appearance is not uncommon; there are three reported cases in which radiologic presentation was confused with vascular etiologies because the initial presentation was acute hemorrhage.[ 1 22 31 ] Differential diagnoses in imaging are ependymoma [surgicalneurologyint.com]

Epidemiology Reliable epidemiological data regarding astroblastoma are not available. These lesions are most common in young adults, but may occur in infants and children. [prod.wiki.cns.org]

Definition / general Rare ( 3% of primary brain gliomas), compact glial neoplasm with perivascular pseudorosettes formed of GFAP cells arranged around central, often sclerotic, blood vessels Controversial entity - relationship with ependymoma is not clear Epidemiology [pathologyoutlines.com]

Astroblastomas: a Surveillance, Epidemiology, and End Results (SEER)-based patterns of care analysis. [futuremedicine.com]

Astroblastomas: a Surveillance, Epidemiology, and End Results (SEER)-based patterns of care analysis. World Neurosurg 2014; 82 (01) (02) e291-e297 10 Asha U, Mahadevan A, Sathiyabama D. et al. [thieme-connect.com]

Epidemiological, clinical, radiologic, and immunohistochemical characteristics and grading are summarized in Table 1. [ncbi.nlm.nih.gov]

We report two patients with astroblastoma who presented with hemorrhage and discuss the natural history, radiological findings, pathophysiology of hemorrhage and histopathological characteristics. [ncbi.nlm.nih.gov]

It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. [books.google.ro]

Its rarity has prevented evidenced-based treatment stratification. An 8-year-old boy presented with signs and symptoms of raised intracranial pressure. [ncbi.nlm.nih.gov]

There are no guidelines or methods available for the prevention of Astroblastoma, since the exact cause or risk factors are not known Active research is currently being performed to explore the possibilities for treatment and prevention of disorders such [dovemed.com]

Valproate therapy for prevention of posttraumatic seizures: a randomized trial. J Neurosurg 1999; 91 : 593 –600. Temkin NR, Dikmen SS, Wilensky AJ, et al. A randomized, double-blinded study of phenytoin for the prevention of post-traumatic seizures. [n.neurology.org]

At that point, January 2009, it was time to begin radiation to prevent regrowth of the tumor, which required 6 more long weeks of treatment. We had a great deal of love and support from the people around us and God used them to carry us through. [caringbridge.org]

presented a discussion on rape culture and the role men can play in preventing sexual violence last fall. “I’ve had the chance to spend some time with Emma and Lilly and their family,” Franklin said. [watertowndailytimes.com]