Presentation
CONCLUSIONS: The present study showed that although HAstV infections occur at low frequency, they are involved in severe pediatric cases of acute gastroenteritis presenting with a high diversity of strains, including the lineages 3c and 4c, which were [ncbi.nlm.nih.gov]
With the evidence presented here, we highlight the need for future research as well as the potential for astrovirus to be a target for vaccine development. [jhu.pure.elsevier.com]
Entire Body System
- Fever
[…] infected with classic HAstV is highly variable, ranging from newborns to over 5 years; however, infection is more common among those younger than 2.Typically, HAstV infection induces a mild, watery diarrhea that lasts 2 to 3 days, associated with vomiting, fever [certest.es]
These studies have shown that HAstV infections are clinically milder (diarrhea, vomiting, fever) than infections with other enteric agents. Among the 8 serotypes of HAstV identified, serotype 1 is the predominant strain worldwide. [kjp.or.kr]
IMPORTANCE: Human astroviruses (HAstVs) infect nearly every person in the world during childhood and cause diarrhea, vomiting, and fever. [ncbi.nlm.nih.gov]
- Asymptomatic
Upon phylogenetic analysis, the nucleotide sequences showed high similarity to type 5 between the patients, asymptomatic controls, asymptomatic food handler and ground water (Figure 2). [omicsonline.org]
Of 217 childrentested, 73 (34%) were infected with astrovirus; infections in 35 (48%) were symptomatic and in 38 (52%) asymptomatic. The six outbreaks lasted 11 to 44 days (median 22 days). [jpeds.com]
Supporting this are studies demonstrating that astroviruses can also be isolated in a subset of asymptomatic individuals, suggesting that a proportion of infected individuals shed the virus asymptomatically or for some time after the resolution of other [springer.com]
- Pain
Symptoms of diarrhea, vomiting, and abdominal pain generally persist for only a few days. [web.stanford.edu]
[…] variable, ranging from newborns to over 5 years; however, infection is more common among those younger than 2.Typically, HAstV infection induces a mild, watery diarrhea that lasts 2 to 3 days, associated with vomiting, fever, anorexia, and abdominal pain [certest.es]
Typically, HAstV infection induces a mild, watery diarrhea that lasts 2 to 3 days, associated with vomiting, fever, anorexia, and abdominal pain. [savyondiagnostics.com]
Ten individuals experienced general clinical symptoms, which included abdominal pain, diarrhea, and headache. [omicsonline.org]
- Fatigue
Other symptoms such as general malaise, low grade fever, nausea and fatigue are also present in over 90% of cases. The incubation period of the disease is generall between 12 and 48 hours, while infection lasts between 12 and 60 hours. [certest.es]
Indications of dehydration in adults These include: Excessive thirst Dry mouth or skin Little or no urination Weakness, dizziness or lightheadedness Fatigue Dark-colored urine Indications of dehydration in infants and young children These include: Not [mayoclinic.org]
Entamoeba histolytica Abdominal cramps Diarrhea Passage of 3 - 8 semiformed stools per day Passage of soft stools with mucus and occasional blood Fatigue Intestinal gas (excessive flatus) Rectal pain while having a bowel movement (tenesmus) Unintentional [wikidoc.org]
In addition, physical fatigue in riot police that have been dispatched and returned may decrease the tolerance against astrovirus infection and lead to the onset of symptoms. [omicsonline.org]
Fruit juice and coconut water can restore carbohydrates and help with fatigue. Avoid caffeine, which may irritate the digestive tract. [healthline.com]
- Malaise
[…] children in childcare backgrounds or adults in military barracks are most likely to develop the disease Human disease An important infection of Astrovirus is called gastroenteritis, and the main symptoms are diarrhoea, followed by nausea, vomiting, fever, malaise [wikidoc.org]
Symptoms include diarrhea, vomiting, nausea, fever, malaise and abdominal pain. Symptoms will generally dissipate on their own within a period of 3 to 4 days. [virology.microbiologyguide.com]
Other symptoms such as general malaise, low grade fever, nausea and fatigue are also present in over 90% of cases. The incubation period of the disease is generall between 12 and 48 hours, while infection lasts between 12 and 60 hours. [certest.es]
Gastrointestinal
- Diarrhea
In this 1 case, HAstV-2 was detected in a sample 1 week before the start of diarrhea, and 2 consecutive stool samples taken during the diarrhea episode and 1 taken after the diarrhea episode were negative for HAstV by both RT-PCR analysis and EIA We tested [academic.oup.com]
Abstract Astroviruses are a known cause of human diarrhea. Recently the highly divergent astrovirus MLB1 (MLB1) was identified in a stool sample from a patient with diarrhea. [ncbi.nlm.nih.gov]
[…] among children, resulting in outbreaks of diarrhea and occasionally hospitalization. [kjp.or.kr]
- Vomiting
Vomiting duration was similar for AsV and SaV (about 3 days) and slightly longer than for NoV (about 2 days); median diarrhea duration was about 5 days for all three viruses. [mdedge.com]
We found vomiting associated with 75% of the positive cases, fever with 82.3%, and dehydration with 76.9%. [ncbi.nlm.nih.gov]
Symptoms of diarrhea, vomiting, and abdominal pain generally persist for only a few days. [web.stanford.edu]
However, severe cases of vomiting and diarrhea ought to be treated by a doctor. Note that, if left untreated vomiting and diarrhea can cause serious weight loss, dehydration or even death. [whatisstomachflu.com]
[…] children infected with classic HAstV is highly variable, ranging from newborns to over 5 years; however, infection is more common among those younger than 2.Typically, HAstV infection induces a mild, watery diarrhea that lasts 2 to 3 days, associated with vomiting [certest.es]
- Acute Diarrhea
Keywords: Epidemiology | Acute gastroenteritis | Diarrhea | Human astrovirus | Serotype [kjp.or.kr]
Most of studies on acute diarrhea have been made on infants aged below 5 years and few efforts have been made to identify the etiological agents of acute diarrhea in people over five, especially in China. 271 diarrhea cases and 149 healthy controls over [ddd.uab.cat]
We have previously described the identification of several sequence fragments with limited sequence identity to known astroviruses in a stool specimen obtained from a child with acute diarrhea, suggesting that a novel virus was present. [ncbi.nlm.nih.gov]
Acute diarrhea was defined as diarrhea lasting less than 14 days at the time of admission. Persistent diarrhea was defined as diarrhea lasting more than 14 days. [scielo.br]
- Nausea
Three weeks after the third fludarabine course he presented with a 5-day-history of watery diarrhoea, nausea and vomiting. [ncbi.nlm.nih.gov]
In humans, Astrovirus causes gastroenteritis, characterized by diarrhoea, nausea, vomiting, fever and abdominal pain. Infection is common, usually not severe and often asymptomatic. [bio-rad-antibodies.com]
In humans, Astrovirus causes gastroenteritis, characterised by diarrhoea, nausea, vomiting, fever and abdominal pain. Infection is common, usually not severe and often asymptomatic. [mybiosource.com]
Gene was looking up my symptoms online the other night (Diarrhea, stomache pain, nausea) and found some references to the Astrovirus.. So the poor guy has a new nickname now! At least he forgot about Astro-ganoff for now :| [flickr.com]
Common symptons of astrovirus include nausea, vomiting and diarrhea. Human astroviruses are transmitted by contact with infected individuals and formited, followed by the ingestion of contaminated food and water. [mid.journals.ekb.eg]
- Abdominal Pain
Symptoms of diarrhea, vomiting, and abdominal pain generally persist for only a few days. [web.stanford.edu]
Typically, HAstV infection induces a mild, watery diarrhea that lasts 2 to 3 days, associated with vomiting, fever, anorexia, and abdominal pain. [savyondiagnostics.com]
Ten individuals experienced general clinical symptoms, which included abdominal pain, diarrhea, and headache. [omicsonline.org]
Psychiatrical
- Suggestibility
It has been suggested that nsP1a/4 protein is involved in the RNA replication process in endoplasmic reticulum-derived intracellular membranes. [ncbi.nlm.nih.gov]
We observe that distinct transmission zones determine the prevailing astrovirus host and virus diversity, which in turn suggests that no single host group (e.g., bats) can be the natural reservoir, as illustrated through our phylogenetic analysis. [research.monash.edu]
Strong preliminary studies suggest that diverse viral genotypes co-circulate in pediatric oncology patients with boys being four times more likely to be infected than girls, and that viruses isolated from patients have distinct in vitro phenotypes. [grantome.com]
Neurologic
- Seizure
She was then transferred to the general pediatric ward under the impression of a febrile seizure. However, during the following hours seizures reoccurred. [jmedicalcasereports.biomedcentral.com]
Initially, the prolonged seizures ceased after systemic midazolam treatment and were thought to be fever associated. However, her mental status remained altered, and after seizure recurrence, she was transferred to our pediatric intensive care unit. [edoc.rki.de]
[…] we - + + + + Undercooked meats More common in hunters or people who eat traditionally uncooked meats Taenia spp Any ages - 1 larva or egg 2-4 m - + + + + Undercooked beef and pork Neurocysticercosis: Cysts located in the brain may be asymptomatic or seizures [wikidoc.org]
Multiorgan dysfunction developed, including hepatic dysfunction and pulmonary infiltrates with respiratory distress and seizures, which required patient admission to the intensive care unit. [journals.plos.org]
- Irritability
But when diarrhea lasts beyond a few days into weeks, it usually indicates that there's another problem — such as irritable bowel syndrome (IBS) or a more serious disorder, including persistent infection, celiac disease or inflammatory bowel disease [mayoclinic.org]
The main target of this process is to reduce its irritant property. The earlier cultures are performed, the greater the chance of obtaining a positive result. It is useful in many diseases mainly in which Virechana recommended. [portalvalidation.ldc.com]
Avoid caffeine, which may irritate the digestive tract. Decaffeinated teas with soothing herbs such as chamomile, peppermint, and dandelion may help calm an upset stomach. Read about more remedies for an upset stomach. [healthline.com]
By mid-December, the patient had become increasingly withdrawn, irritable, and intermittently agitated. He remained lymphopenic (lymphocytes 0.54 × 10 6 /μL [normal range, 1.2–3.6 × 10 6 /μL]). [academic.oup.com]
Workup
Colonoscopy
- Colitis
unspecified 2016 2017 2018 2019 Billable/Specific Code Applicable To Colitis NOS Enteritis NOS Gastroenteritis NOS Ileitis NOS Jejunitis NOS Sigmoiditis NOS Type 1 Excludes diarrhea NOS ( R19.7 ) functional diarrhea ( K59.1 ) infectious gastroenteritis [icd10data.com]
인터넷에서 구한 amebic colitis 내시경 사진 몇 개를 모았습니다. 어느 것도 flask-shpaed ulcer는 아니군요. 아메바 장염 아메바 장염. 아메바 장염. 간혹 Behcet colitis에서 large undermining ulcer가 발견되는데 오히려 이를 flask-shaped ulcer라고 부를 수 있지 않을까요? 홍성노 선생님께서 제공해주신 Behcet colitis 사진 3개를 소개합니다. [endotoday.com]
A06 이질 아메바에 의한 감염 Infection due to Entamoeba histolytica A060 급성 아메바이질 Acute amoebic dysentery A060 급성 아메바증 Acute amoebiasis A060 장아메바증 NOS Intestinal amoebiasis NOS A061 만성 장아메바증 Chronic intestinal amoebiasis A062 아메바성 비이질성 결장염 Amoebic nondysenteric colitis [druginfo.co.kr]
May cause bacteremia, Guillain-Barré syndrome (GBS), hemolytic uremic syndrome (HUS) and recurrent colitis Yersinia enterocolitica <10 y - 104 -106 1-11 d + + + + + Meats (pork, beef, lamb, etc.), oysters, fish, crabs, and raw milk. [wikidoc.org]
Treatment
The report covers exhaustive analysis on: Astrovirus Infection Treatment Market Segments Astrovirus Infection Treatment Market Dynamics Historical Actual Market Size, 2013 - 2017 Astrovirus Infection Treatment Market Size & Forecast 2017 to 2026 Astrovirus [persistencemarketresearch.com]
Symptomatic treatment was given but since his condition deteriorated, high-dose intravenous immunoglobulin (IvIg) treatment, 0.4 g/kg for four days was initiated. [ncbi.nlm.nih.gov]
Etiology
MeSH terms Adolescent Agammaglobulinemia/complications* Agammaglobulinemia/genetics Astroviridae Infections/diagnosis* Astroviridae Infections/etiology Capsid Proteins/analysis Capsid Proteins/genetics Encephalitis, Viral/diagnosis* Encephalitis, Viral [ncbi.nlm.nih.gov]
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
Epidemiology
A better understanding of the molecular epidemiology and characteristics of HAstV strains may be valuable to develop specific prevention strategies. Keywords: Epidemiology | Acute gastroenteritis | Diarrhea | Human astrovirus | Serotype [kjp.or.kr]
The understanding of molecular epidemiology and molecular processing of the virus may lead to specific prevention strategies. [journals.lww.com]
The data provide an epidemiological overview of HAstV infection and HAstV genotype distribution in Thailand. Copyright © 2012 Wiley Periodicals, Inc. [ncbi.nlm.nih.gov]
The changing epidemiology of astrovirus‐associated gastroenteritis: a review. ]. [clinicalmicrobiologyandinfection.com]
Pathophysiology
DOI https://doi.org/10.31274/rtd-180813-12257 Publisher Digital Repository @ Iowa State University, http://lib.dr.iastate.edu/ Copyright Owner Mari Lynn Thouvenelle File Format application/pdf Recommended Citation Thouvenelle, Mari Lynn, "The pathophysiology [lib.dr.iastate.edu]
For example, little or no information is available on the in vivo cell tropism, pathophysiology, and host responses. [grantome.com]
Prevention
Control and Prevention, Shandong Center for Disease Control and Prevention, Jinan, People's Republic of China. 3 1] School of Public Health, Shandong University, Jinan, People's Republic of China [2] Academy of Preventive Medicine, Shandong University [ncbi.nlm.nih.gov]
Epidemiology of astrovirus infection in children Division of Enteric and Hepatitis Viruses, Center for Infectious Disease, Korea National Institute of Health, Korea Centers for Disease Control and Prevention, Cheongwon, Korea Corresponding Author: Doo-Sung [kjp.or.kr]
Molecular Epidemiology of Human Astroviruses Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centres for Disease Control and Prevention, Atlanta, GA, USA Search for more papers by this [doi.org]
The new findings provide a roadmap for researchers to design a vaccine based on the spike domain that can induce neutralizing antibodies and prevent infection in children. [news.ucsc.edu]