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Astrovirus

Astroviruses


Presentation

  • CONCLUSIONS: The present study showed that although HAstV infections occur at low frequency, they are involved in severe pediatric cases of acute gastroenteritis presenting with a high diversity of strains, including the lineages 3c and 4c, which were[ncbi.nlm.nih.gov]
  • We have previously described the identification of several sequence fragments with limited sequence identity to known astroviruses in a stool specimen obtained from a child with acute diarrhea, suggesting that a novel virus was present.[ncbi.nlm.nih.gov]
  • The group of children between 2 and 5 years old presented the higher percentage of infections.[ncbi.nlm.nih.gov]
  • RESULTS: The detection limit of LAMP using in vitro RNA transcripts was 3.6 10 copies·μL ¹, which is as sensitive as the presently used PCR assays.[ncbi.nlm.nih.gov]
  • Three weeks after the third fludarabine course he presented with a 5-day-history of watery diarrhoea, nausea and vomiting.[ncbi.nlm.nih.gov]
Burkina Faso
  • STUDY DESIGN: Viral nucleic acids were enriched from the feces from 48 cases of unexplained diarrhea from Burkina Faso, sequenced, and compared against all known viral genomes.[ncbi.nlm.nih.gov]
  • Nitiema, Xutao Deng and Eric Delwart , New astrovirus in human feces from Burkina Faso , Journal of Clinical Virology , 60 , 2 , (161) , (2014) . Albert Bosch, Rosa M.[doi.org]
  • New astrovirus in human feces from Burkina Faso. J. Clin.[mdpi.com]
Weight Gain
  • CAstV Chicken astrovirus has been associated with runting-stunting syndrome (RSS) in chickens characterized by poor weight gain, lower feed conversion, and mortality resulting in economic losses [ 97 ], and “white chicks” disease associated with increased[mdpi.com]
Regurgitation
  • Pathogenesis Clinical signs and pathology Both adult and juvenile cheetahs present with signs of lethargy, partial to complete anorexia, diarrhea and regurgitation over an a short period of time.[awp.eduwikis.co.za]
Hypotension
  • Despite these interventions, he developed new symptoms of central dyspnea, postural hypotension, nausea, and gradually worsening balance. Repeat neurological assessment confirmed persistent vestibulocochlear dysfunction 6 weeks after symptom onset.[academic.oup.com]
Lethargy
  • The initial signs include mild lethargy, and partial anorexia that progress to a watery diarrhea and vomition.[awp.eduwikis.co.za]

Workup

Colitis
  • , unspecified 2016 2017 2018 2019 Billable/Specific Code Applicable To Colitis NOS Enteritis NOS Gastroenteritis NOS Ileitis NOS Jejunitis NOS Sigmoiditis NOS Type 1 Excludes diarrhea NOS ( R19.7 ) functional diarrhea ( K59.1 ) infectious gastroenteritis[icd10data.com]

Treatment

  • Symptomatic treatment was given but since his condition deteriorated, high-dose intravenous immunoglobulin (IvIg) treatment, 0.4 g/kg for four days was initiated.[ncbi.nlm.nih.gov]
  • […] of cells (blocking effect), direct viral activity (virucidal effect) and post-treatment of infected cells (reduction of viral yield post-infection).[ncbi.nlm.nih.gov]
  • In this work we present several experimental findings that show that human astrovirus (HAstV) RNA encodes a VPg essential for viral infectivity: (i) RNase treatment of RNA purified from astrovirus-infected cells results in a single protein of 13 to 15[ncbi.nlm.nih.gov]
  • Large immune aggregates were found after treatment of the faecal specimen with pooled human immunoglobulin.[ncbi.nlm.nih.gov]
  • Treatment consisted in symptomatic care and the outcome was favorable.[ncbi.nlm.nih.gov]

Etiology

  • MeSH terms Adolescent Agammaglobulinemia/complications* Agammaglobulinemia/genetics Astroviridae Infections/diagnosis* Astroviridae Infections/etiology Capsid Proteins/analysis Capsid Proteins/genetics Encephalitis, Viral/diagnosis* Encephalitis, Viral[ncbi.nlm.nih.gov]
  • Astrovirus infection might constitute a common etiology of gastroenteritis in patients with hematologic malignancies that have been severely immunocompromised with FAMP or other purine analogues, and therefore should be more systematically investigated[ncbi.nlm.nih.gov]
  • Abstract Many diseases with unknown etiology may be caused by unidentified viruses. Sequence-independent amplification revealed a new astrovirus, similar to VA1, in a 4-year-old male diagnosed with celiac disease.[ncbi.nlm.nih.gov]
  • In order to provide more insights into the epidemiology of enteric viruses that are not included usually in routine diagnostic tests, cases of childhood sporadic gastroenteritis of unknown etiology requiring hospital admission in Parma, Italy, during[ncbi.nlm.nih.gov]
  • Author information 1 Laboratory of Molecular Microbiology, Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russian Federation. [email protected] Abstract Human astrovirus is one of the etiological agents of acute gastroenteritis in[ncbi.nlm.nih.gov]

Epidemiology

  • Data on the epidemiology and the response to the outbreak was collected. RESULTS: All samples had a 99% match to human astrovirus type 5.[ncbi.nlm.nih.gov]
  • The data provide an epidemiological overview of HAstV infection and HAstV genotype distribution in Thailand. Copyright 2012 Wiley Periodicals, Inc.[ncbi.nlm.nih.gov]
  • KEYWORDS: astrovirus; encephalitis; epidemiology; gastroenteritis; meningitis; zoonosis[ncbi.nlm.nih.gov]
  • This report provides an epidemiological overview of SaV and HAstV infection in Nara Prefecture, Japan.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Prevention

  • Control and Prevention, Shandong Center for Disease Control and Prevention, Jinan, People's Republic of China. 3 1] School of Public Health, Shandong University, Jinan, People's Republic of China [2] Academy of Preventive Medicine, Shandong University[ncbi.nlm.nih.gov]
  • This review focuses on the basic virology, pathogenesis, host response, epidemiology, diagnostic assays, and prevention strategies for HAstVs.[ncbi.nlm.nih.gov]
  • Molecular Epidemiology of Human Astroviruses Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centres for Disease Control and Prevention, Atlanta, GA, USA Search for more papers by this[doi.org]
  • Antibodies work by binding to the spike domain and preventing virus cells from attaching to and infecting human cells.[contagionlive.com]

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