Presentation
Two cases involving retinal detachment caused by breaks in the pars plicata of the ciliary body are presented. In both, retinal detachment developed following surgery for atopic cataract. [ncbi.nlm.nih.gov]
We discuss in detail about the presentation, clinical features, and surgical management of these patients presenting with RD, cataracts and related clinical problems secondary to severe AD. [nature.com]
Case presentation We report two cases of children with AD who developed posterior sub-capsular cataracts. [jmedicalcasereports.biomedcentral.com]
Cardiovascular
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Vascular Disease
Master the latest advances in ophthalmology: radical changes in the management of macular disease, including the widespread introduction of VEGF inhibitor therapy; recent developments in the investigation and treatment of retinal vascular disease; new [books.google.com]
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Tachycardia
[…] vision. [12] [13] People with Parkinson's disease are at risk of falling due to gait disturbances, loss of motion control including freezing and jerking, autonomic system disorders such as orthostatic hypotension, fainting, and postural orthostatic tachycardia [en.wikipedia.org]
Skin
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Facial Skin Lesion
Indeed, the presence of facial skin lesions in AD correlates with progression of the cataract [ 3 ]. An alternative hypothesis suggests that the cataract is secondary to compromise of the blood-aqueous barrier. [jmedicalcasereports.biomedcentral.com]
In a study of 41 patients, Nagaki et al. (20) showed that cataract progression was statistically significantly related to facial skin lesions. [medicaljournals.se]
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Macula
He developed a macula off, temporal retinal detachment in his right eye due to a GRT, extending 180 degrees. PPV, cryopexy, and gas tamponade was performed and vision recovered to 6/12. [nature.com]
Swelling or edema of the central part of the retina, called macula, resulting in macular edema, can occur a few days or weeks after surgery. Most such cases can be successfully treated. [en.wikipedia.org]
Eyes
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Thickened Eyelids
Retinal examination can be difficult due to corneal problems, thickened eyelids making indentation tough and also cataract may obscure the retinal details. [nature.com]
– Eyelid margin thickening: Eyelid margins may be thickened, oedematous and hyperaemic. – Dennie-Morgan lines: Eyelid oedema may lead to Dennie-Morgan lines, single or double creases in the lower eyelid, secondary to chronic eye rubbing. – Lateral canthal [aimu.us]
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Corneal Opacity
Approximately 25% of female carriers have minor corneal opacities. The corneal opacities are not known to affect visual acuity. An example of findings in X-linked ichthyosis is shown in the image below. [emedicine.medscape.com]
Psychiatrical
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Suggestibility
This case seems to suggest that prompt control of severe dermatitis on the face in patients with atopic dermatitis is important for prevention of atopic cataract, whether the dermatitis on the face is atopic or nonatopic in nature. [ncbi.nlm.nih.gov]
This case seems to suggest that prompt control of severe dermatitis on the face in patients with atopic dermatitis is important for prevention of atopic cataract, whether the dermatitis on the face is atopic or nonatopic in nature. 1986 S. [karger.com]
Workup
Infants with bilateral cataracts and failure to thrive should receive a full metabolic workup in conjunction with a pediatrician and geneticist, if possible. [aao.org]
[…] syndrome, with affected males presenting with dense visually significant cataracts. 20 Investigations Although 60% of pediatric cataracts are idiopathic, 40 based on the antenatal history, family history, and the type of cataract, a baseline laboratory workup [dovepress.com]
Treatment
Apply the latest best practices through new and updated treatment algorithms. Find therapeutic drug information more easily with guidance incorporated into each chapter. [books.google.com]
Inadequate treatment of atopic dermatitis may lead to other ocular complications such as keratitis and permanent visual loss. [jmedicalcasereports.biomedcentral.com]
Treatment. The only known effective treatment for cataract is surgical removal of the lens (lens extraction or cataract extraction). The procedure of choice was formerly intracapsular extraction, with total removal of the lens within its capsule. [medical-dictionary.thefreedictionary.com]
Prognosis
Only an estimated 10% of patients older than 20 years continue to be symptomatic. [5] Prognosis The prognosis is good if the inflammation can be kept under control with therapy. [emedicine.medscape.com]
– Visual prognosis: Visual prognosis is worse for AKC. – Peri-orbital skin and eyelid: There is increased peri-orbital and eyelid skin involvement in AKC as compared to VKC which generally spare skin. – Papillae: AKC usually presents with micro-papillae [aimu.us]
What is the prognosis of cataracts? The rate of progression of cataracts is usually predictable and surgery is successful in restoring vision in a large majority of cases. [medicinenet.com]
It can rarely deteriorate to symptomatic keratoconjunctivitis that may have a poor prognosis. Statistical methods Continuous variables were expressed as mean and standard deviation. Categorical variables were expressed as percentages. [medicaljournals.se]
Prognosis [ 2, 15 ] Adults Age-related cataracts are progressive and the progression is variable and unpredictable. Without treatment, most people with a cataract will develop severe visual impairment. [patient.info]
Etiology
The etiology, and therefore the basic pathophysiology, of childhood cataract varies widely; in many children, the etiology may not be determined. [aao.org]
Etiological factors in keratoconus.Ophthalmology. 1995;102(suppl):156 57) Zadnik K, Barr JT, Edrington TB, et al. [gatinel.com]
Slit lamp appearance of the eyes is shown below: What type of cataract is this and what is the etiology? These cataracts have an unusual appearance because of the refractile intralenticular crystals, which are cholesterol deposits. [ophthalmologyweb.com]
Complete retinal detachment (both eyes): with special reference to allergy as a possible primary etiologic factor. Am J Ophthalmol 1937; 20 : 580–582. 2. Ingram RM. Retinal detachment associated with atopic dermatitis and cataract. [nature.com]
In fact, the etiology of allergic cataract has not been fully elucidated until recently. 2,6 We now know that the allergic process itself causes the cataract, with allergy as the probable initiating factor. [crstodayeurope.com]
Epidemiology
American journal of epidemiology, 137(3), 342-354 Winter DA, Patla AE, Frank JS, Walt SE. Biomechanical walking pattern changes in the fit and healthy elderly. Phys Ther. 1990;70(6):340–347. Elble RJ, Thomas SS, Higgins C, Colliver J. [en.wikipedia.org]
J Dermatol 1999;26:658-65. [ PUBMED ] [Table 1], [Table 2] This article has been cited by 1 Epidemiology and clinical features of atopic dermatitis in India Kanwar, A., De, D. [ijdvl.com]
Trends in the epidemiology and prescribing of medication for eczema in England. J R Soc Med 2009; 102 (3): 108–117. 4. Eiseman AS. The ocular manifestations of atopic dermatitis and rosacea. Curr Allergy Asthma Rep 2006; 6 (4): 292–298. 5. [nature.com]
Nonetheless, patients frequently have a history of food or inhalant allergies or eventually develop them. [3] Epidemiology Frequency United States An estimated 3-12% of the population will be affected at some point during their lifetime. [emedicine.medscape.com]
Pathophysiology
Despite much current research interest, the pathophysiology of these disorders and their optimum treatment remain uncertain. [books.google.com]
Conclusions: : Our results suggested that PAI-1 and TGF-β1 synergistically play some roles for the pathophysiology of atopic cataracts. [iovs.arvojournals.org]
Atopic Glaucoma: Clinical and Pathophysiological Analysis. [benthamopen.com]
Allergic conjunctivitis: Update on pathophysiology and prospects for future treatment. J Allergy Clin Immunol. 2005; 115:118-22. Bielory L. Allergic and Immunologic Disorders of the Eye. Part II: Ocular Allergy. [verywell.com]
Atopic dermatitis: therapeutic concepts evolving from new pathophysiologic insights. J Allergy Clin Immunol. 2008 Dec. 122(6):1074-81. [Medline]. Bezan DJ. Eye itch. Bezan DJ, Larussa FP, Nishimoto JH, et al, eds. [emedicine.medscape.com]
Prevention
This case seems to suggest that prompt control of severe dermatitis on the face in patients with atopic dermatitis is important for prevention of atopic cataract, whether the dermatitis on the face is atopic or nonatopic in nature. [ncbi.nlm.nih.gov]
This case seems to suggest that prompt control of severe dermatitis on the face in patients with atopic dermatitis is important for prevention of atopic cataract, whether the dermatitis on the face is atopic or nonatopic in nature. 1986 S. [karger.com]
[…] for Disease Control and Prevention Preventing Falls: What Works―A CDC Compendium of Effective Community-based Interventions from Around the World US Centers for Disease Control and Prevention (PDF) Preventing Falls: How to Develop Community-based Fall [en.wikipedia.org]
The end result is a decrease in degranulation of mast cells, which prevents release of histamine and other chemotactic factors that are present in the preformed and newly formed state. [emedicine.medscape.com]