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Atrial Arrhythmia


Presentation

  • In this review, we first present findings that have yielded a robust and detailed biophysical representation of fibrotic substrate electrophysiological properties.[ncbi.nlm.nih.gov]
  • Evidence for a focal atrial arrhythmia was present in 20 of the total group of 50 patients (40%).[ncbi.nlm.nih.gov]
  • Abstract We discuss the case of a 38-year-old black man who presented at our hospital with his first episode of syncope, recently developed atrial arrhythmias refractory to pharmacologic therapy, and a left atrial thrombus.[ncbi.nlm.nih.gov]
  • Thirty-nine patients (25.2%) presented with late atrial arrhythmia.[ncbi.nlm.nih.gov]
  • OBJECTIVES: We present three patients in whom atrial arrhythmia was treated by ablation of electrical conduction across a surgical suture line.[ncbi.nlm.nih.gov]
Respiratory Distress
  • They reported a case of severe cardiopulmonary toxicity (acute respiratory distress syndrome and AF) after gemcitabine infusion and suggest an inflammatory pathogenetic mechanism mediated by cytokine release resulting in myofibroblast proliferation and[onlinejacc.org]
Heart Disease
  • METHODS: Discussion of the history of anti-arrhythmic treatments in congenital heart disease.[ncbi.nlm.nih.gov]
  • METHODS: Data from ASD type secundum patients, included in the Belgian Congenital Heart Disease Registry, were analyzed.[ncbi.nlm.nih.gov]
  • No risk factors for cerebro-vascular disease or significant valvular heart disease were present. Return to sinus rhythm was achieved in 143 (91%) procedures.[ncbi.nlm.nih.gov]
  • Abstract Atrial arrhythmia (AA) is common in adult patients with congenital heart disease (CHD). To enable the prevention of AA or its complications, timely identification of adult patients with CHD at risk of AA is crucial.[ncbi.nlm.nih.gov]
  • BACKGROUND: In patients late after surgical repair of congenital heart disease (CHD), areas with abnormal electrophysiologic properties may serve as slow conducting pathways within a macroreentrant circuit or may be the source of focal atrial tachycardia[ncbi.nlm.nih.gov]
Tachycardia
  • The mechanism of atrial tachycardia was scar related intra-atrial reentry (n 27), cavotricuspid-related atrial flutter (n 21), atrial fibrillation (n 2), or focal atrial tachycardia (n 10).[ncbi.nlm.nih.gov]
  • All patients with RA origin of the tachycardia were successfully ablated.[ncbi.nlm.nih.gov]
  • The data set used in this study shows that, for 78.08% of infants, the occurrence of tachycardia can be accurately predicted.[ncbi.nlm.nih.gov]
  • RESULTS: Paroxysmal supraventricular tachycardia terminated after adenosine administration in 198 patients (99% [95% CI, 96% to 100%]).[ncbi.nlm.nih.gov]
  • Few studies explore the impact of early AF (EAF) and atrial tachycardia (EAT) on long-term outcomes. Furthermore, EAF/EAT have not been characterized after wide pulmonary vein isolation.[ncbi.nlm.nih.gov]
Skipped Beats
  • Here’s how patients have described their experience: “My heart flip-flops, skips beats, and feels like it’s banging against my chest wall, especially if I’m carrying stuff up my stairs or bending down.” “I was nauseated, light-headed, and weak.[heart.org]
  • While some people can't tell they even have AFib, most describe the following heart-related symptoms: •Skipping beats •Flip-flopping •Beating fast and/or hard Other common symptoms include: •Weakness •Fatigue •Shortness of breath •Light-headedness •Chest[pnj.com]
  • With AFib, your heart quivers, beats too quickly, or skips beats. It can't pump blood through its chambers and out to your body as well as it should. Sometimes blood can pool in the heart and form clots, which could lead to a stroke .[webmd.com]
  • With AFib, your heart quivers, beats too quickly, or skips beats. It can't pump blood through its chambers and out to your body as well as it should. Sometimes blood can pool in the heart and form clots, which could lead to a stroke.[webmd.com]
Polyuria
  • 23 (82%) 0.999 Nausea 19 9 (13%) 10 (36%) 0.012 Vomiting 2 1 (1%) 1 (4%) 0.484 Abdominal pain 5 2 (3%) 3 (11%) 0.312 Loss of appetite 31 20 (28%) 11 (39%) 0.336 Anxiety 59 37 (51%) 22 (79%) 0.014 Reduced physical capacity 87 62 (86%) 25 (89%) 0.999 Polyuria[bmccardiovascdisord.biomedcentral.com]
  • Further, frequent urination (Polyuria) may be associated with the release of atrial natriuretic peptide, particularly as episodes of AF begin or terminate. [3] An irregular pulse should raise the suspicion of AF.[physio-pedia.com]
Stroke
  • Stroke physicians and cardiologists differ in their diagnosis and management of these patients.[ncbi.nlm.nih.gov]
  • METHODS: An online survey was sent to cardiologists and stroke physicians in the UK, via their national societies. RESULTS: A total of 205 clinicians responded to the survey (130 stroke physicians, 64 cardiologists, 11 other).[ncbi.nlm.nih.gov]
  • If a clot breaks off, enters the bloodstream and lodges in an artery leading to the brain, a stroke results. About 15–20 percent of people who have strokes have this heart arrhythmia.[heart.org]
  • Blood-thinning (anticoagulants) medications may be prescribed to reduce stroke risk following atrial fibrillation.[dukemedicine.org]
  • Anticoagulant (blood thinner) medications are the most effective treatment for preventing blood clots and lowering your risk of stroke. Anticlotting medications (antiplatelet agents) also can lower your risk for stroke.[uncmedicalcenter.org]
Polyneuropathy
  • BACKGROUND: Cardiac autonomic dysfunction is a common complication of familial amyloidotic polyneuropathy (FAP), but cardiac arrhythmia and conduction disturbances are also common.[ncbi.nlm.nih.gov]

Workup

  • […] disease, sleep apnoea, and other respiratory diseases Chronic kidney disease Integrated management of patients with atrial fibrillation Evidence supporting integrated atrial fibrillation care Components of integrated atrial fibrillation care Diagnostic workup[escardio.org]
Dyslipidemia
  • BACKGROUND: Lifestyle-related diseases, such as obesity and dyslipidemia are important risk factors for atrial fibrillation (AF). However, the underlying mechanism linking these diseases and AF has not been fully investigated.[ncbi.nlm.nih.gov]
2:1 Atrioventricular Block
  • 1 atrioventricular block) 4:1 is also common (3:1 and 1:1 block uncommon) Atrial fibrillation P waves absent; oscillating baseline f (fibrillation) waves Atrial rate 350-600 beats/min Irregular ventricular rhythm Ventricular rate 100-180 beats/min As[bmj.com]
Premature Atrial Contractions
  • Types of Supraventricular Arrhythmias Supraventricular arrhythmias begin in the atria Types of supraventricular arrhythmias include: Premature atrial contractions (PACs) Early, extra heartbeats that originate in the atria.[my.clevelandclinic.org]
  • Premature Supraventricular Contractions Also called “premature atrial contractions” (PACs), they happen when the atria contract too soon, causing the heart to beat out of sequence.[texasheart.org]
Left Atrial Hypertrophy
  • An echocardiogram showed some left atrial hypertrophy and septal hypokinesis, but it remained unclear if this was caused by the steroids. He was hospitalized and converted spontaneously to SR after two days of stopping the intake of the steroids.[onlinejacc.org]
Electrocardiogram Change
  • Other side effects of clozapine such as orthostatic hypotension, sinus tachycardia, heart failure, and electrocardiogram changes are well known ( 60 ).[onlinejacc.org]

Treatment

  • Sarcoidosis is important in the differential diagnosis because of its progressive nature and its potential for treatment with pharmacologic, surgical, and catheter-based interventions.[ncbi.nlm.nih.gov]
  • METHODS: Discussion of the history of anti-arrhythmic treatments in congenital heart disease.[ncbi.nlm.nih.gov]
  • If you think you may have atrial fibrillation, here are your most important steps: Know the symptoms Get the right treatment Reduce risks for stroke and heart failure We’re here to help you live your healthiest life![heart.org]
  • In many cases, effective treatment of such rhythm disorders is severely hindered by a lack of mechanistic understanding relating features of fibrotic remodelling to dynamics of re-entrant arrhythmia.[ncbi.nlm.nih.gov]
  • The unique statistical properties of this type of distribution should be considered in designing outcome measures for treatment of atrial tachyarrhythmias.[ncbi.nlm.nih.gov]

Prognosis

  • ., in terms of atrial arrhythmia in the natural prognosis and the surgically modified course and in terms of surgical versus transcatheter approaches.[ncbi.nlm.nih.gov]
  • Frequency and prognosis of arrhythmias after operative ‘correction’ of tetralogy of Fallot. Am J Cardiol . 1990 ; 66 :346-349. Crossref Medline Google Scholar 15 Burns RJ, Liu PP, Druck MN, Seawright SJ, Williams WG, McLaughlin PR.[ahajournals.org]
  • In this Review, Ko et al . discuss sex-specific differences in the incidence, prevalence, risk factors, and pathophysiology of atrial fibrillation, and the clinical presentation and prognosis of patients with this prevalent arrhythmia.[nature.com]
  • Prognosis Patients with atrial fibrillation and flutter can live a normal life for many years as long as the arrhythmia is controlled and serious blood clots are prevented.[medical-dictionary.thefreedictionary.com]
  • Those who respond poorly to treatments will have a poorer prognosis. VFib needs immediate treatment (CPR and defibrillation) or the person will likely die within a few minutes.[medicinenet.com]

Etiology

  • KEYWORDS: Atrial fibrillation; fibrosis; granuloma/pathology; sarcoidosis, cardiac/diagnosis/etiology/epidemiology/therapy/pathology[ncbi.nlm.nih.gov]
  • Bryan Au discuss the presentation, etiology, precipitants, management and disposition of Atrial Fibrillation in the Emergency Department.[emergencymedicinecases.com]
  • But first, a word about the etiology, classification, and diagnosis of AF.[mdedge.com]
  • Alcohol has long been considered to play an etiological role in PAF, a correlation underlined in the expression "holiday heart" [ 11 ].[bmccardiovascdisord.biomedcentral.com]
  • Etiology and mechanisms of AF Atrial fibrillation is associated with morphologic changes in the atrial myocardium.[onlinejacc.org]

Epidemiology

  • KEYWORDS: Atrial fibrillation; fibrosis; granuloma/pathology; sarcoidosis, cardiac/diagnosis/etiology/epidemiology/therapy/pathology[ncbi.nlm.nih.gov]
  • SETTING: The Rochester Epidemiology Project (REP). PARTICIPANTS: Elderly adults consecutive undergoing hip fracture repair from 1988 to 2002 in Olmsted County, Minnesota (N 1,088, mean age 84.0 7.4, 80.2% female).[ncbi.nlm.nih.gov]
  • In this Review, Ling and colleagues present the current understanding of the epidemiology and pathophysiology of AF–HF, and the roles of pharmacological and interventional therapies in the management of patients with this comorbidity.[nature.com]
  • Journal (2010) 31, 2369–2429 Published in 2010 Reference AFIB - Additional References Published in 2011 Reference ESC Statement on Dronedarore Table of contents: Full Text (ESC Clinical Practice Guidelines) Abbreviations and acronyms Preamble Introduction Epidemiology[escardio.org]
Sex distribution
Age distribution

Pathophysiology

  • In this Review, Ko et al . discuss sex-specific differences in the incidence, prevalence, risk factors, and pathophysiology of atrial fibrillation, and the clinical presentation and prognosis of patients with this prevalent arrhythmia.[nature.com]
  • Permanent AF is not an inherent pathophysiologic attribute of AF, but rather an acceptance of AF where the patient and physician abandon further efforts to restore and/or maintain sinus rhythm.[mdedge.com]
  • Acceptance of permanent AF represents a therapeutic attitude on the part of the patient and clinician rather than an inherent pathophysiological attribute of AF.[physio-pedia.com]
  • Introduction Epidemiology and impact for patients Incidence and prevalence of atrial fibrillation Morbidity, mortality, and healthcare burden of atrial fibrillation Impact of evidence-based management on outcomes in atrial fibrillation patients Gender Pathophysiological[escardio.org]

Prevention

  • A 3-month randomized crossover trial of atrial preventative pacing features did not result in adverse effects, but there was no clinical efficacy for prevention of AT/AF.[ncbi.nlm.nih.gov]
  • OBJECTIVES: This study sought to determine the risk of TEC in this population and the role of anticoagulation therapy in TEC prevention.[ncbi.nlm.nih.gov]
  • In this paper, a data mining algorithm (G-algorithm) is proposed for extraction of robust rules that can be used in clinical practice for better understanding and prevention of unwanted medical events.[ncbi.nlm.nih.gov]
  • Based on the evidence of a biological effect of the atrial therapies (burden reduction) studies to determine of the effects of AT/AF prevention and termination algorithms on morbidity and quality of life in ICD recipients are underway.[ncbi.nlm.nih.gov]
  • Further studies are indicated to determine whether prevention of PAA will reduce mortality in this population. 2015, Copyright the Authors Journal compilation 2015, The American Geriatrics Society.[ncbi.nlm.nih.gov]

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