Presentation
Methods The clinical presentation and subsequent clinical course pertaining to an individual 9 year-old girl who ingested Deadly Nightshade berries are presented. [adc.bmj.com]
Patients may present to the emergency department with a psychotic picture [3]. [ncbi.nlm.nih.gov]
We present an infant who suffered serious seizures after ingestion of a homeopathic agent containing A. belladonna. [journals.lww.com]
The child presented at the ER with an atropinic syndrome, both central and peripheral, after ingestion of wild berries a few hours before. [semanticscholar.org]
Entire Body System
- Pain
Belladonna is used in ointments that are applied to the skin for joint pain (rheumatism), leg pain caused by a disc in the backbone pushing on the sciatic nerve ( sciatica ), and nerve pain (neuralgia). [webmd.com]
Syndrome (PBS) / Urinary Bladder, Neurogenic / Urinary Bladder, Overactive / Urinary Urge Incontinence 1 4 Completed Treatment Calcium Nephrolithiasis 1 4 Completed Treatment Hysterectomy / Postoperative pain 1 4 Completed Treatment Pain 1 4 Completed [drugbank.ca]
Belladonna is used in ointments that are applied to the skin for joint pain (rheumatism), leg pain caused by a disc in the backbone pushing on the sciatic nerve (sciatica), and nerve pain (neuralgia). 10. [slideshare.net]
Belladonna is used in ointments that are applied to the skin for joint pain, pain along the sciatic nerve, and general nerve pain. [emedicinehealth.com]
Thus, it is crucial to realize that AB poisoning should be taken into consideration in the patients with flushing, xeroderma with mydriasis, tachycardia, tremor, abdominal pain and fever symptoms. [mona.uwi.edu]
- Fever
Fever : Belladonna might increase the risk of overheating in people with fever. Stomach ulcers : Belladonna might make stomach ulcers worse. [webmd.com]
Signs include dryness of the mouth, thirst, dilated pupils, tachycardia, fever and stupor. [medical-dictionary.thefreedictionary.com]
The patient was treated with intravenous benzodiazepines and antibiotics after a full sepsis work up; all the laboratory results were normal and the fever resolved after several hours. [journals.lww.com]
Thus, it is crucial to realize that AB poisoning should be taken into consideration in the patients with flushing, xeroderma with mydriasis, tachycardia, tremor, abdominal pain and fever symptoms. [mona.uwi.edu]
- Inflammation
and endocarditis (inflammation of the lining of the heart). [livingnaturally.com]
Companies claim it helps with: colds flu fever cough sore throat inflammation joint and back pain earache gout Is It Safe to Take Belladonna? Belladonna should be safe for you if your doctor prescribes it and you take it as directed. [healthline.com]
This is used especially in cases where there is localised and painful inflammation that radiates heat[232]. It is also used to treat sunstroke and painful menstruation[238]. Other Uses Soil reclamation. [pfaf.org]
Traditional and alternative medicine A. belladonna has been used in traditional treatments for centuries for an assortment of conditions including headache, menstrual symptoms, peptic ulcer disease, histaminic reaction, inflammation, and motion sickness [tititudorancea.com]
Berries of belladonna.A. belladonna has been used in traditional treatments for centuries for an assortment of conditions including headache, menstrual symptoms, peptic ulcer disease, histaminic reaction, inflammation, and motion sickness, with at least [plainfieldgardenclub.org]
- Falling
Check out our blog featuring fall indoor plant tips . [ambius.com]
It falls in catalepsy and in a twenty hours deep sleep during which he was tormented by horrible visions: monsters, infernal landscapes, diabolic beings and satanic creatures. [flipper.diff.org]
The song portrays an abusive relationship - but also tells a story about falling in love with such toxicity. Lady Gaga's Debut Perfume "Fame" Contains "Tears" of Belladonna as a top note in the perfume to give it a unique scent. [horticultureandsoilscience.wikia.com]
But the condition can quickly progress to shock, which is marked by falling blood pressure and body temperature, confusion, clotting abnormalities and bleeding into the skin. Blood poisoning is a medical emergency and can be fatal if left untreated. [livingnaturally.com]
- Epilepsy
A drawing of the plant PROPERTIES OF BELLADONNA Medicinal uses of belladonna - Remedies with Belladonna : It has been traditionally used to combat stomach cramps, epilepsy and asthma. - Medicines with belladonna: components of this plant are used to make [botanical-online.com]
In the nineteenth century, root and herb extracts were used for whooping cough, nervous ailments, scarlet fever, epilepsy, skin diseases, eye inflammation, and urinary and respiratory tract infections (Schneider 1974 cited in Ratsch 1998, 83). [entheology.com]
It is often serviceable in chorea and in epilepsy, with congestion. It is also recommended in infantile convulsions of an epileptiform character. [henriettes-herb.com]
Respiratoric
- Cough
The plant has been used as an anesthetic for surgery and extracts from the roots was used as a remedy for a malignant cough or a whooping-cough. Extracts of the plant are still used in the pharmaceutical industry. [herbal-supplement-resource.com]
Whooping cough. Colds. Hay fever. Parkinson's disease. Motion sickness. Arthritis -like pain. Nerve problems. Hemorrhoids. Spasms and colic -like pain in the stomach and bile ducts. Other conditions. [webmd.com]
Though widely regarded as unsafe, belladonna is taken by mouth as a sedative, to stop bronchial spasms in asthma and whooping cough, and as a cold and hay fever remedy. [emedicinehealth.com]
Belladonna is used as a sedative, to stop bronchial spasms in asthma and whooping cough, and as a cold and hay fever remedy. [slideshare.net]
Its medical applications include use as a pain reliever, muscle relaxer, anti-inflammatory, and as a treatment for whooping cough and hay fever. [ambius.com]
Gastrointestinal
- Overeating
[…] the Counter You can purchase belladonna products over the counter at your local pharmacy or health food store. [healthline.com]
Apparently, the bottle fell over and the atropine dripped onto some cooked meat below. Her mother only realised something was wrong when she began hallucinating after making herself a ham sandwich. [thepoisongarden.co.uk]
Also has a drying effect and in large doses can affect the brain, resulting in over excitement and hallucinations. Taken internally it induces sleep, loss of voice, fevers and racing pulse. The sap of the plant can cause dermatitis. [hermionesgarden.blogspot.com]
When she was finally caught and executed, it was believed that Tofana had assisted in the poisoning of over 600 men throughout Italy. [deathscent.com]
Grows in well-lit forests all over Europe, diminishing northwards. Characteristics and poison Deadly nightshade ranks among the most poisonous plants in Europe. All parts of the plant are poisonous, and contain tropane alkaloids. [poisonousnature.biodiversityexhibition.com]
Liver, Gall & Pancreas
- Jaundice
The evolution was marked by neurological improvement (GCS:15), disappearance of delirium, regression of jaundice and normalization of laboratory tests. [ncbi.nlm.nih.gov]
Avoid in newborns due to the potential for an increase in free bilirubin, jaundice, and development of kernicterus. [livingnaturally.com]
Cardiovascular
- Tachycardia
Thus, it is crucial to realize that AB poisoning should be taken into consideration in the patients with flushing, xeroderma with mydriasis, tachycardia, tremor, abdominal pain and fever symptoms. [mona.uwi.edu]
Signs include dryness of the mouth, thirst, dilated pupils, tachycardia, fever and stupor. [medical-dictionary.thefreedictionary.com]
"Atropa belladonna contains solanaceous alkaloids which can cause anticholinergic symptoms including dry mouth, tachycardia (abnormally high heart rate) and blurred vision. High dose can lead to confusion, hallucination or seizure. [info.gov.hk]
Rapid heartbeat (tachycardia) : Belladonna might make rapid heartbeat worse. Ulcerative colitis : Belladonna might promote complications of ulcerative colitis. [webmd.com]
University NHS Trust, Romford, UK 2 Regional Drugs and Therapeutics Centre, National Poisons Information Service, Newcastle-upon-Tyne, UK Abstract Aims To present the case of a 9 year-old child who presented with confusion, hallucinations, agitation, tachycardia [adc.bmj.com]
- Hypotension
The peripheral effect are mydriasis with cycloplegia, dry mucous membranes, hyperreflexia, flushed skin, diminished bowel sounds or ileus, urinary retention, tachycardia, and hypertension or hypotension. [flipper.diff.org]
Peripheral effects include mydriasis with cycloplegia, dry mucous membranes, hyperreflexia, flushed skin, diminished bowel sounds or ileus, urinary retention, tachycardia, and hypertension or hypotension 1. [drugbank.ca]
The peripheral effects that are common to anticholinergic agents include mydriasis with cycloplegia, dry mucous membranes, hyperreflexia, flushed skin, diminished bowel sounds or ileus, urinary retention, tachycardia, and hypertension or hypotension [ [panafrican-med-journal.com]
Musculoskeletal
- Muscle Spasm
Atropine and scopolamine have almost the same uses, but atropine is more effective at relaxing muscle spasms and regulating heart rate. It’s also used to dilate the pupils during an eye exam. [healthline.com]
It overcomes spasm of the involuntary, but is less effectual in spasm of the voluntary, muscles. Spasm of the anus, biliary spasm, uterine, cystic, intestinal and urethral spasms, and spasm of the ureters are relieved by it. [henriettes-herb.com]
Eyes
- Visual Impairment
Handling the berries can cause eruptions on the face and visual impairment. People have reportedly died after dining on birds and rabbits which have fed on the berries. [hermionesgarden.blogspot.com]
Skin
- Flushing
Thus, it is crucial to realize that AB poisoning should be taken into consideration in the patients with flushing, xeroderma with mydriasis, tachycardia, tremor, abdominal pain and fever symptoms. [mona.uwi.edu]
He displayed psychomotor agitation, confusion, flushed and warmed skin, urinary retention, dry mouth and dilated pupils within 3 hours of ingesting of a plant, Atropa belladonna, which has been used as a traditional folk remedy for relieving peptic ulcer [pjms.com.pk]
Symptoms include dryness of the mouth, thirst, dilated pupils, flushed skin or rash on the face, neck, and upper trunk, tachycardia, fever, delirium, and stupor. [medical-dictionary.thefreedictionary.com]
5-lobed, dull red-purple or greenish purple; fruit a glossy, purple-black berry Family: Solanaceae Origin: Eurasia Poison Part: All parts, mainly berries Poison Delivery Mode: Ingestion Symptoms: Fever, rapid pulse, dilation of pupils, hot and dry flushed [plants.ces.ncsu.edu]
Moving further with the information on toxicity of deadly nightshade, the symptoms of belladonna poisoning is almost similar to those for atropine which include fever, hallucination, dilation of pupils, headache, flushed skin, nausea, loss of balance, [belladonnakillz.com]
- Skin Rash
rash, stomach discomfort, stomach ulcers, and vomiting. [livingnaturally.com]
There are many possible symptoms of poisoning, including: rapid heartbeat dry mouth slurred speech light sensitivity blurred vision inability to urinate loss of balance flushed skin a rash memory loss seizures confusion hallucinations Severe poisoning [owlcation.com]
Psychiatrical
- Euphoria
Euphoria, crying fits, agitation, thought disturbance, confusion, screaming, diverse hallucinations, frenzy, rage and madness often occur as well. Death may result from respiratory paralysis. [entheology.com]
Neurologic
- Confusion
The risk of poisoning in children is important because of possible confusion with other berries. [ncbi.nlm.nih.gov]
Conclusion The case and background information highlights the importance of considering poisoning in the differential diagnosis of children with confusion, hallucinations and agitation. [adc.bmj.com]
Cases of deadly nightshade intoxication may also be confused with post-traumatic brain damage, and acute psychosis. [panafrican-med-journal.com]
He displayed psychomotor agitation, confusion, flushed and warmed skin, urinary retention, dry mouth and dilated pupils within 3 hours of ingesting of a plant, Atropa belladonna, which has been used as a traditional folk remedy for relieving peptic ulcer [pjms.com.pk]
- Seizure
We present an infant who suffered serious seizures after ingestion of a homeopathic agent containing A. belladonna. [journals.lww.com]
High dose can lead to confusion, hallucination or seizure. It is not recommended for human consumption, including leaves and fruits. In addition, the root of the plant is generally found to be the most toxic part," a spokesman for the CHP explained. [info.gov.hk]
Absorbing enough belladonna could cause hallucinations and seizures, too. Back to questions [poison.org]
The toxicity associated with physostigmine consists mostly of seizures and cardiac arrhythmia, and occurs when used in the absence of anticholinergic symptoms. [panafrican-med-journal.com]
- Agitation
Conclusion The case and background information highlights the importance of considering poisoning in the differential diagnosis of children with confusion, hallucinations and agitation. [adc.bmj.com]
He displayed psychomotor agitation, confusion, flushed and warmed skin, urinary retention, dry mouth and dilated pupils within 3 hours of ingesting of a plant, Atropa belladonna, which has been used as a traditional folk remedy for relieving peptic ulcer [pjms.com.pk]
Benzodiazepines may be used for sedation if the patient is very agitated [2]. [panafrican-med-journal.com]
At high levels, atropine can block signals in the nervous system, "which in turn causes the very fast heart rate, red skin and acute agitation and confusion [as] we saw in our case," Chadwick said. [livescience.com]
- Mydriasis
Thus, it is crucial to realize that AB poisoning should be taken into consideration in the patients with flushing, xeroderma with mydriasis, tachycardia, tremor, abdominal pain and fever symptoms. [mona.uwi.edu]
The peripheral effect are mydriasis with cycloplegia, dry mucous membranes, hyperreflexia, flushed skin, diminished bowel sounds or ileus, urinary retention, tachycardia, and hypertension or hypotension. [flipper.diff.org]
Peripheral effects include mydriasis with cycloplegia, dry mucous membranes, hyperreflexia, flushed skin, diminished bowel sounds or ileus, urinary retention, tachycardia, and hypertension or hypotension 1. [drugbank.ca]
The peripheral effects that are common to anticholinergic agents include mydriasis with cycloplegia, dry mucous membranes, hyperreflexia, flushed skin, diminished bowel sounds or ileus, urinary retention, tachycardia, and hypertension or hypotension [ [panafrican-med-journal.com]
- Ataxia
Central nervous effect are ataxia, disorientation, short-term memory loss, confusion, hallucinations, psychosis, agitated delirium, seizures, coma, respiratory failure or cardiovascular collapse. [flipper.diff.org]
Central symptoms, which are dose-dependent and anticholinergic agent-specific, include ataxia, disorientation, short-term memory loss, confusion, hallucinations, psychosis, agitated delirium, seizures, coma, respiratory failure or cardiovascular collapse [drugbank.ca]
Central effects are dose-dependent and agent-dependent [5], Patients with central anti-cholinergic syndrome may present with ataxia, disorientation, short-term memory loss, confusion, hallucinations, psychosis, agitated delirium, seizures, coma, respiratory [panafrican-med-journal.com]
Treatment
He survived after treatment with intravenous administration of physostigmine. [ncbi.nlm.nih.gov]
Treatment Vaginal Surgery 1 4 Recruiting Treatment Urinary Tract Infection 1 4 Terminated Treatment Urinary Bladder, Overactive 1 Not Available Completed Supportive Care Elective Cystoscopy / General Surgery / Ureteroscopy 1 Not Available Completed Treatment [drugbank.ca]
Astasis complaint was relatively higher (p Conclusions: AB poisoning may seriously progress in the act of late diagnosis and treatment in childhood. [mona.uwi.edu]
Belladonna is used as a powder (0.3% belladonna alkaloids, calculated as hyoscyamine) and tincture in the treatment of diarrhea, asthma, colic, and hyperacidity. [medical-dictionary.thefreedictionary.com]
Etiology
Among the causes of this, toxic etiology due to a herbal medicine is not rare. This article reports a case who was brought to emergency department because of the anticholinergic syndrome. [pjms.com.pk]
Therefore, in case of excitability and confusion, as well as somnolence or coma of uncertain etiology, an anticholinergic syndrome caused by ingestion of atropine-containing plants or psychoactive drugs should be included in the differential diagnosis [panafrican-med-journal.com]
Epidemiology
"Blood Pressure" [SH] (epidemiology AND humans) [SH] SI Secondary Source ID The SI field identifies secondary source databanks and accession numbers, e.g., GenBank, GEO, PubChem, ClinicalTrials.gov, ISRCTN. [biomedsearch.com]
Epidemiology Frequency United States Incidence is sporadic, with clusters of poisoning cases, mostly among adolescents using plants for their hallucinogenic effects. [emedicine.medscape.com]
[PubMed] [Google Scholar] Articles from The Pan African Medical Journal are provided here courtesy of African Field Epidemiology Network [ncbi.nlm.nih.gov]
Pathophysiology
Pathophysiology Toxicity from plants containing tropane alkaloids manifests as classic anticholinergic poisoning. [emedicine.medscape.com]
Prevention
"The public should avoid picking atropa belladonna for consumption in order to prevent poisoning. If symptoms of poisoning develop, they should immediately consult medical professionals for advice and prompt treatment," the spokesman urged. [info.gov.hk]
Midwives would use it to help prevent miscarriages and others would use it during childbirth to ease labor. A salve applied topically can induce a trance-like or altered state inducing the infamous "witches flight" that many attribute to this herb. [rdalchemy.com]
Tea tree oil : Tea tree oil is purported to have antiseptic properties, and has been used traditionally to prevent and treat infections. [livingnaturally.com]
Atropine blocks the muscarinic receptors of the system, preventing the acetylcholine from transmitting nerve impulses. [owlcation.com]