The distinction was historically considered important, as it differentiated those more likely to present with "typical" respiratory symptoms and lobar pneumonia from those more likely to present with "atypical" generalized symptoms (such as fever, headache [en.wikipedia.org]

We need to return to the original meaning of atypical pneumonia and restrict its use to describe pneumonia that is truly unusual in clinical presentation, epidemiology, or both. [ncbi.nlm.nih.gov]

• Fever

  During the later stages of the illness, symptoms may worsen, the fever may become higher, and coughing may yield discolored phlegm (sputum). [my.clevelandclinic.org]

  Clinical findings Incubation ± 3 weeks; insidious onset of fever, malaise, headache, myalgia, low-grade fever, cough, chest pain and respiratory disease, from asymptomatic to rhinitis, pharyngitis, tracheobronchitis and pneumonia. [medical-dictionary.thefreedictionary.com]

  His fever subsided soon and clinical symptoms improved after minocycline was administrated on Day 12. The psittacosis case was confirmed by history of psittacine bird contact, clinical symptoms, treatment response, and positive IgM titer. [ncbi.nlm.nih.gov]

  The likelihood of OP increased with increasing duration of fever (LR+ for more than three days and more than five days of fever, respectively: 1.62; 95% CI = 1.13 to 2.31 and 2.24; 95% CI = 1.35 to 3.71). [doi.org]

  He had history of prolonged low grade fever and non-productive cough for 5 days. [omicsonline.org]

• Malaise

  All are marked by extensive but short-lived pulmonary infiltration, fever, malaise, muscle pains, sore throat, and coughing. Copyright 2007. An Elsevier publication. All rights reserved. [web.archive.org]

  None had received the seasonal influenza vaccine; they had cough (92%), fever (86.8%), and malaise (73.7%). The median time from disease onset to hospital admission was 6 days (range 0-8 days). [ncbi.nlm.nih.gov]

  Atypical bacterial pneumonia generally is characterised by a symptom complex that includes headache, low-grade fever, cough, and malaise. Constitutional symptoms often predominate over respiratory findings. [bestpractice.bmj.com]

  Clinical findings Incubation ± 3 weeks; insidious onset of fever, malaise, headache, myalgia, low-grade fever, cough, chest pain and respiratory disease, from asymptomatic to rhinitis, pharyngitis, tracheobronchitis and pneumonia. [medical-dictionary.thefreedictionary.com]

• Asymptomatic

  Clinical findings Incubation ± 3 weeks; insidious onset of fever, malaise, headache, myalgia, low-grade fever, cough, chest pain and respiratory disease, from asymptomatic to rhinitis, pharyngitis, tracheobronchitis and pneumonia. [medical-dictionary.thefreedictionary.com]

  It is thought to cause 20% of all lower airway infections, and that 70% of these are either asymptomatic or not serious enough to compel the patient to seek medical attention. [elsevier.es]

  Approximately 40% of those affected are asymptomatic, and marrow failure is rare, and most of patients are diagnosed only when osteomyelitis occurs in the mandible. [hindawi.com]

  Asymptomatic carriers were found with all three mutations, and nonpenetrance rates were 41, 24, and 29%, respectively. Patients with the R767W genotype, which was found in only one family, appeared to manifest only fracture. [academic.oup.com]

• Weakness

  If your immune system is weak, stay away from crowds. Ask visitors who have a cold to wear a mask. DO NOT smoke. If you do, get help to quit. Get a flu shot every year. Ask your provider if you need a pneumonia vaccine. [nlm.nih.gov]

  Pneumonia due to Legionella pneumophila bacteria is seen more often in middle-aged and older adults, smokers, and those with chronic illnesses or a weak immune system. It can be more severe. This type of pneumonia is also called Legionnaire disease. [ufhealth.org]

  This is more likely to occur if: Your immune system is weak A germ is very strong Your body fails to filter out the bacteria from the air that you breathe. [nhlbi.nih.gov]

  However, their altered internal architecture renders them weak. Therefore, patients have dense, sclerotic, fragile bones that fracture easily. [radiopaedia.org]

• Anorexia

  The elderly may present with mainly systemic complaints of malaise, fatigue, anorexia and myalgia. Young children may present with nonspecific symptoms or abdominal pain. [patient.info]

  Initial symptoms include anorexia, vomiting, myalgia and headache. Over 90% of patients present fever between 12 and 24 h after onset of the first symptoms. [elsevier.es]

  The disease usually starts as mild cough, malaise, fatigue, and anorexia. Child can have chest pain, gastrointestinal symptoms and encephalopathy. [indianpediatrics.net]

• Cough

  During the later stages of the illness, symptoms may worsen, the fever may become higher, and coughing may yield discolored phlegm (sputum). [my.clevelandclinic.org]

  It develops gradually with a dry cough and low-grade fever as opposed to sudden fever and coughing up mucus in bacterial pneumonia [1]. [ehealthstar.com]

  […] pri·mar·y a·typ·i·cal pneu·mo·ni·a an older term referring to an acute systemic disease with involvement of the lungs, usually caused by Mycoplasma pneumoniae and marked by fever, cough, relatively few physical signs, and scattered densities on x-rays [medical-dictionary.thefreedictionary.com]

  DO NOT take cough medicines without first talking to your provider. Cough medicines may make it harder for your body to cough up the extra sputum. Drink plenty of fluids to help loosen secretions and bring up phlegm. Get a lot of rest. [nlm.nih.gov]

• Aspiration

  ^ "Aspiration Pneumonitis and Pneumonia: Overview of Aspiration Pneumonia, Predisposing Conditions for Aspiration Pneumonia, Pathophysiology of Aspiration Pneumonia". 3 February 2019. [en.wikipedia.org]

  Involved Can be caused by aspirating microbes fro intestinal tract Never caused by aspiration Environment that stimulates pneumonia Non specific Air conditioned environments where the Air-conditioning systems are not maintained. [differencebetween.net]

  Age over 60 years, aspiration pneumonia, and Gram negative infection were the only factors that independently predicted adverse outcome on adjusted mortality analysis. [ncbi.nlm.nih.gov]

  […] anesthesia during pregnancy ( O29 ) aspiration pneumonia due to anesthesia during puerperium ( O89.0 ) aspiration pneumonia due to solids and liquids ( J69.- ) aspiration pneumonia NOS ( J69.0 ) congenital pneumonia ( P23.0 ) drug-induced interstitial [icd10data.com]

  Aspiration Pneumonia This can develop after a person inhales food, liquid, gases, or dust. [everydayhealth.com]

• Pertussis

  This review will discuss the epidemiology, clinical manifestations, and laboratory diagnosis of Mycoplasma pneumoniae, Chlamydia sp., Legionella sp., Bordetella pertussis, and Coxiella bumetii, the most common agents associated with atypical pneumonia [ncbi.nlm.nih.gov]

  The Mycoplasma pneumoniae PCR assay was tested for cross reactivity against Bordetella pertussis, Bordetella parapertussis, Bordetella bronchiseptica, all relevant species of Chlamydophila, all relevant species of Legionella as well as human herpes viruses [viracoribt.com]

  There may also be dyspnea and, in some cases, the cough may take on a pertussis-like character. Some children may develop inflammation of the throat, cervical adenopathy, conjunctivitis, and myringitis. [phac-aspc.gc.ca]

  An epidemic of a pertussis-like illness caused by Chlamydia pneumoniae. Pediatr Infect Dis J 1999; 18: 271-275. 21. Thom DH, Grayston JT, Wang SP, Kuo CC, Altamn J. [indianpediatrics.net]

• Tachypnea

  (Redirected from Rapid breathing) Tachypnea Other names Tachypnoea Pronunciation Specialty Respirology Tachypnea is abnormally rapid breathing. [en.wikipedia.org]

  Significant fever, tachypnea and tachycardia. PE exam typically demonstrates purulent sputum. Course of disease is much quicker, typically under 5 days of illness before the patient presents. [forums.studentdoctor.net]

  Patients were classified into two groups: “signs of pneumonia” and “no signs of pneumonia” on the basis of the presence or absence of respiratory distress, tachypnea, or lower respiratory tract findings. [doi.org]

  The disease usually starts with upper respiratory tract signs like nasal obstruction with or without discharge, which gradually worsen to cough and tachypnea. [indianpediatrics.net]

• Rales

  As pneumonia progresses, rales appear in the chest, C. penumoniae is known to be associated with hyper-reactive airway. Infec-tion with C. pneumoniae can trigger acute epidosde of wheezing in children with asthma. [indianpediatrics.net]

  Harsh breath sounds from the larger airways that are transmitted through the inflamed lung are termed bronchial breathing and are heard on auscultation with a stethoscope.[20] Crackles (rales) may be heard over the affected area during inspiration.[20 [en.wikipedia.org]

  […] hypothermia (< 35°C) Tachypnea (>18 respirations/min) Use of accessory respiratory muscles Tachycardia (>100 bpm) or bradycardia (< 60 bpm) Central cyanosis Altered mental status Physical findings may include the following: Adventitious breath sounds, such as rales [emedicine.com]

• Loss of Appetite

  Common symptoms of walking pneumonia include chills, cough, headache, fever, muscle aches, muscle stiffness, loss of appetite, shortness of breath, and rapid breathing. [belmarrahealth.com]

  Infection takes 3-5 days to incubate and shows clinical signs like loss of appetite, fever (mild to high), sepsis symptoms, lethargy and other pneumonia symptoms that leads to death. [epainassist.com]

  Comments In addition to fever and respiratory symptoms, SARS may be associated with other symptoms including: headache, muscular stiffness, loss of appetite, malaise, confusion, rash, and diarrhea. * * * Until more is known about the cause of these outbreaks [web.archive.org]

  […] of appetite, low energy, and fatigue Muscle aches and joint stiffness Sweating and clammy skin Less common symptoms include: Diarrhea (often with legionella pneumonia) Ear pain (with mycoplasma pneumonia) Eye pain or soreness (with mycoplasma pneumonia [nlm.nih.gov]

• Chest Pain

  Herein we report a 44-year-old male patient displaying atypical pneumonia symptoms of intermittent fever, dry cough, chest pain, dyspnea, headache, hepatitis, and hyponatremia. He had two sick cockatiels, one of which had died a month previously. [ncbi.nlm.nih.gov]

  Cough, fever, and substernal chest pain were common presenting complaints, and upper respiratory symptoms were often present. White blood cell counts ranged from 6,500 to 18,300/mm 3. [annals.org]

  If you have chest pain or confusion, you should seek emergency care. [emedicinehealth.com]

  Clinical findings Incubation ± 3 weeks; insidious onset of fever, malaise, headache, myalgia, low-grade fever, cough, chest pain and respiratory disease, from asymptomatic to rhinitis, pharyngitis, tracheobronchitis and pneumonia. [medical-dictionary.thefreedictionary.com]

  Minimally to non-productive cough often with chest pain (from cough, not pleuritic) with negative sputum stain. CXR often negative or demonstrating typically unilateral interstitial infiltrate. Mycoplasma is the big one, chlamydia pneumoniae #2. [forums.studentdoctor.net]

• Myalgia

  The key symptoms of atypical pneumonia are fever, headache, sweating and myalgia along with bronchopneumonia. Atypical pneumonia is treated with macrolide class of antibiotics like clarithromycin or erythromycin. [differencebetween.net]

  Clinical findings Incubation ± 3 weeks; insidious onset of fever, malaise, headache, myalgia, low-grade fever, cough, chest pain and respiratory disease, from asymptomatic to rhinitis, pharyngitis, tracheobronchitis and pneumonia. [medical-dictionary.thefreedictionary.com]

  In contrast, atypical CAP is characterized by preceeding upper airway symptoms, myalgias, fever without chills, headache and unproductive cough. [lungindia.com]

  The elderly may present with mainly systemic complaints of malaise, fatigue, anorexia and myalgia. Young children may present with nonspecific symptoms or abdominal pain. [patient.info]

• Eye Pain

  (with mycoplasma pneumonia) Eye pain or soreness (with mycoplasma pneumonia) Neck lump (with mycoplasma pneumonia) Rash (with mycoplasma pneumonia) Sore throat (with mycoplasma pneumonia) People with suspected pneumonia should have a complete medical [nlm.nih.gov]

  (with mycoplasma pneumonia) Eye pain or soreness (with mycoplasma pneumonia) Neck lump (with mycoplasma pneumonia) Rash (with mycoplasma pneumonia) Sore throat (with mycoplasma pneumonia) Exams and Tests People with suspected pneumonia should have a [ufhealth.org]

  […] sweating Symptoms that occur rarely include diarrhea, ear and eye pain, rashes, neck lumps, and sore throat In general, the symptoms may improve after 4 days, but complete recovery takes about 2 weeks Individuals with severe cases of Atypical Pneumonia [dovemed.com]

• Sweating

  The key symptoms of atypical pneumonia are fever, headache, sweating and myalgia along with bronchopneumonia. Atypical pneumonia is treated with macrolide class of antibiotics like clarithromycin or erythromycin. [differencebetween.net]

  […] distinction was historically considered important, as it differentiated those more likely to present with "typical" respiratory symptoms and lobar pneumonia from those more likely to present with "atypical" generalized symptoms (such as fever, headache, sweating [en.wikipedia.org]

  […] yourself) Other symptoms include: Chest pain that gets worse when you breathe deeply or cough Confusion, most often in older people or those with legionella pneumonia Headache Loss of appetite, low energy, and fatigue Muscle aches and joint stiffness Sweating [nlm.nih.gov]

• Skin Rash

  In atypical pneumonia, very few signs, such as crackling sounds during lung auscultation and occasional skin rash (erythema multiforme or nodosum), can be observed [4,17]. Picture 1. [ehealthstar.com]

  rash Your doctor will ask about your symptoms and medical history. [health.cvs.com]

  rash Diagnosis Your doctor will ask about your symptoms and medical history. [winchesterhospital.org]

• Eruptions

  Generalized cutaneous exanthema consisting of pruritic red erythematous plaques with papulovesicular eruptions at their center (bullous target lesions) on the patient's back. Fig. 2. Mucopurulent conjunctivitis and oral mucositis. [archbronconeumol.org]

  Dental problems like delayed tooth eruption, ankylosis, abscesses, cysts, and fistulas are common in patients with benign osteopetrosis. [hindawi.com]

  Skin manifestations include erythema multiforme, erythema nodosum, maculopapular and vesicular eruptions, and urticaria. [aafp.org]

• Increased Sweating

  A risk factor increases ones chances of getting a condition compared to an individual without the risk factors. Some risk factors are more important than others. [dovemed.com]

• Hunger

  By JEN GUNTER Well Photo Credit Illustration by Celia Jacobs Outrunning Hunger Intense exercise may change the way certain neurons influence our appetite and metabolism. [nytimes.com]

  Shortness of breath occurs when the individual is running, climbing up stairs, or swimming Other symptoms that occur less commonly are: Chest pain, confusion (mostly in elderly individuals), headaches, lack of energy, hunger, joint stiffness, increased [dovemed.com]

• Headache

  Despite general symptoms and problems with the upper respiratory tract (such as high fever, headache, a dry irritating cough followed later by a productive cough with radiographs showing consolidation), there are in general few physical signs. [en.wikipedia.org]

  Herein we report a 44-year-old male patient displaying atypical pneumonia symptoms of intermittent fever, dry cough, chest pain, dyspnea, headache, hepatitis, and hyponatremia. He had two sick cockatiels, one of which had died a month previously. [ncbi.nlm.nih.gov]

  These might include a prominent headache, a low-grade fever, an earache, and a sore throat. [medicalnewstoday.com]

  Atypical bacterial pneumonia generally is characterised by a symptom complex that includes headache, low-grade fever, cough, and malaise. Constitutional symptoms often predominate over respiratory findings. [bestpractice.bmj.com]

• Confusion

  As such, the use of atypical pneumonia is often inaccurate, potentially confusing, and of dubious scientific merit. [ncbi.nlm.nih.gov]

  In mycoplasma pneumonia specifically, a rash may appear, while those with legionella pneumonia may also experience diarrhea and confusion. [belmarrahealth.com]

  This can result in severe headaches and confusion Severe infections of the lung due to the disease can cause permanent lung damage, in some rare cases. [dovemed.com]

  This diversity is, in part, what causes the confusion; antibiotics are no use against viral pneumonia, and vice versa. There are also significant variations in severity. [bustle.com]

Challenges in Community-Acquired Pneumonia American Family Physician Atypical pneumonia General Practice Notebook Bono MJ, Mycoplasmal pneumonia Emedicine Bono MJ, Mycoplasmal pneumonia, clinical presentation Emedicine Bono MJ, Mycoplasmal pneumonia, workup [ehealthstar.com]

Urine assays Sputum, serum, and/or urinary antigen tests Immune serologic tests Histologic examination Histologic inflammatory lung changes vary according to whether the patient has lobar pneumonia, bronchopneumonia, or interstitial pneumonia. [2] See Workup [emedicine.com]

• Atelectasis

  Subsegmental and sometimes segmental atelectasis from small airway obstruction may occur. The radiographic features are often more extensive than what is suggested clinically. [radiopaedia.org]

  Other findings that suggest the presence of pneumonia include air bronchograms; the silhouette sign; parapneumonic effusions; and complications of pneumonia, such as lung abscesses, and atelectasis. [emedicine.medscape.com]

  Children treated as outpatients should have a follow-up examination within 24 to 72 hours. 31 View/Print Table TABLE 3 Conditions that May Mimic Community-Acquired Pneumonia Acute respiratory distress syndrome Atelectasis Bronchiolitis obliterans with [aafp.org]

• Legionella Pneumophila

  Pneumonia due to Chlamydia pneumoniae, Legionella pneumophila or Mycoplasma pneumoniae seems to be rare in Danish human immunodeficiency virus-infected patients, but might be considered as a possible cause in cases of treatment failure. [ncbi.nlm.nih.gov]

  Review article DOI: 10.1016/j.hgmx.2015.06.005 Atypical pneumonias caused by Legionella pneumophila, Chlamydophila pneumoniae and Mycoplasma pneumonia Neumonías atípicas causadas por Legionella pneumophila, Chlamydophila pneumoniae y Mycoplasma pneumoniae [elsevier.es]

In the azithromycin treatment group, Mycoplasma pneumoniae was identified in 65, Chlamydia spp. in 9 and Coxiella burnetti in 1 patient. [ncbi.nlm.nih.gov]

Treatment failure: as defined in study, with and without treatment modifications. 21. Mechanical ventilation. 22. Adverse events: life‐threatening events, events necessitating specific medical treatment, events requiring cessation of treatment. [doi.org]

CONCLUSION: This analysis of pneumonia in the Al-Qassim area indicates the pattern and prognosis of acute bacterial and atypical pneumonia that requires admission to hospital in the central region of Saudi Arabia. [ncbi.nlm.nih.gov]

Prognosis for the AD adult subtype is good with a reasonable life expectancy. [radiopaedia.org]

Prognosis. Chlamydia pneumoniae infection is usually mild, but may last for several weeks or months; in older individuals, it may be life-threatening; mortality among individuals treated with antibiotics is ~5% [9,11]. [ehealthstar.com]

Noninfectious etiologies must be considered in atypical and nonresolving pneumonias. [emedicine.medscape.com]

M. pneumoniae was an important microorganism in the etiology of atypical pneumonia of childhood in our community. [ncbi.nlm.nih.gov]

Abstract INTRODUCTION According to Smadel, 16 "Primary atypical pneumonia is a clinical-pathological entity which has a diverse etiology. [annals.org]

SUMMARY: There are few advances in our knowledge of the epidemiology of atypical pathogens or the effectiveness of antimicrobial therapy--empirical or pathogen specific. [ncbi.nlm.nih.gov]

Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 56 (‎20)‎, 158. https://apps.who.int/iris/handle/10665/223490 Revue Weekly Epidemiological Record = Relevé épidémiologique hebdomadaire, 56 (‎20)‎: 158 [apps.who.int]

There are few advances in our knowledge of the epidemiology of atypical pathogens or the effectiveness of antimicrobial therapy - empirical or pathogen specific. [journals.lww.com]

Amongst pathophysiological causes, tachypnea can be a symptom of sepsis, compensation for diabetic ketoacidosis or other metabolic acidosis, pneumonia, pleural effusion, carbon monoxide poisoning, pulmonary embolism, asthma, COPD, laryngospasm, allergic [en.wikipedia.org]

References Cheng AC, BartJC (2005) Melioidosis: Epidemiology, Pathophysiology, andManagement, Clinical Microbiology Review 12: 383-416. [omicsonline.org]

Pathophysiology The organism responsible for mycoplasmal pneumonia, M pneumoniae, is a pleomorphic organism that, unlike bacteria, lacks a cell wall, and unlike viruses, does not need a host cell for replication. [emedicine.com]

Centers of Disease Control and Prevention [ehealthstar.com]

Medicine, Hygiene | keywords: | published on: 23.6.2016 Loaóza discipline: Epidemiology, Preventive Medicine, Hygiene | keywords: | published on: 21.12.2016 Dirofilarióza discipline: Epidemiology, Preventive Medicine, Hygiene | keywords: | published [portal.mefanet.cz]

(November 6, 2017) Centers for Disease Control and Prevention. CDC Features: Pneumonia can be prevented—vaccines can help. Available online at https://www.cdc.gov/Features/Pneumonia/. Accessed on September 8, 2018. [labtestsonline.it]

CONCLUSION: TCM intervention could effectively control and alleviate the symptoms and prevent the disease from exacerbation. [ncbi.nlm.nih.gov]