Presentation
At present, the clinician has neither of these ( Nelson et al., 1996 ; Wheatcroft et al., 1997 ). [academic.oup.com]
In addition, in the present case, the marked increase in luteinizing hormone with relatively normal follicle stimulating hormone raises the possibility of a non-steroidal inhibitory feedback of follicle stimulating hormone. [ncbi.nlm.nih.gov]
الصفحة 37 - Defective presentation to class I-restricted cytotoxic T lymphocytes in vaccinia-infected cells is overcome by enhanced degradation of antigen. J Exp Med 168: 1211 22. [books.google.com]
Here we present two cases of young women with premature ovarian failure who were treated with glucocorticoids in the hopes of restoring fertility. [olympias.lib.uoi.gr]
Weight loss will also occur with hypopituitarism which also presents with secondary amenorrhoea. [endobible.com]
Musculoskeletal
- Knee Pain
Glucocorticoid administration is the most frequent cause of osteonecrosis of the hip or knee ( Mankin, 1992 ). Pain is usually the presenting symptom of osteonecrosis, and the pain exacerbates with the use of the joint. [academic.oup.com]
Urogenital
- Amenorrhea
METHOD OF STUDY: The medical history of three young women who presented with secondary amenorrhea following HPV vaccination was collected. [ncbi.nlm.nih.gov]
[…] before the age of 40 years (secondary amenorrhea) [ 1, 2 ]. [ojrd.biomedcentral.com]
M Sobral, J Dias, O Viseu Keywords hormonal replacement, hypergonadotropic hypogonadism, premature ovarian failure, primary amenorrhea, savage syndrome Citation M Sobral, J Dias, O Viseu. Premature Ovarian Failure in a 16 year old girl. [ispub.com]
Women with POF or early menopause will have high FSH, low estrogen, and amenorrhea or no menstrual periods. In many cases, POF can begin in women in their 20s, and it affects on average 1% of women overall. [whitelotusclinic.ca]
Chatzikosta’ General State Hospital, Ioannina, Greece * Corresponding author Email: [email protected] Abstract Introduction Autoimmune oophoritis is a rare condition, which provokes ovarian failure with either primary amenorrhea or secondary amenorrhea [oapublishinglondon.com]
- Secondary Amenorrhea
METHOD OF STUDY: The medical history of three young women who presented with secondary amenorrhea following HPV vaccination was collected. [ncbi.nlm.nih.gov]
[…] before the age of 40 years (secondary amenorrhea) [ 1, 2 ]. [ojrd.biomedcentral.com]
Autoimmune oophoritis is a distinct clinical entity and one of the causes of POF, particularly in women with secondary amenorrhea [ 6, 7, 8 ]. [oapublishinglondon.com]
[…] and 4–18% in those with secondary amenorrhea. 4 POI may be developed as a result of many pathogenic mechanisms such as chromosomal or genetic abnormalities, autoimmune, infectious, or iatrogenic causes. [glowm.com]
Among younger women (aged 30 years or younger) with secondary amenorrhea, 13% also have been noted to have an abnormal karyotype ( 5 ). [acog.org]
- Ovarian Disorder
Disorders The ovaries are part of the female reproductive system. [icdlist.com]
- Adnexal Mass
Case reports Case 1 A 26-year-old woman (gravida 2, para 1, abortus 1) presented to her private physician with acute abdominal pain and a right adnexal mass. At surgery, a 7 cm multiloculated cystic structure was removed from the right ovary. [academic.oup.com]
Workup
If your doctor runs a fertility workup and concludes you have diminished ovarian reserve or even premature ovarian failure, it doesn't mean you won't ever have children. [self.com]
The diagnostic workup is aimed at determining theetiology where possible and is followed by a screenfor syndromic conditions. Estrogen replacement and fertility options need tobe reassessed at intervals and clinicians have to bevigilant for psychological [slideshare.net]
Imaging Studies Primary ovarian insufficiency: Ovarian ultrasonography can be useful in the workup of patients with POI/POF as it will identify those women with multifollicular ovaries and suggest the diagnosis of either autoimmune oophoritis or 17-20 [emedicine.medscape.com]
Serum
- Abnormal Thyroid Function Test
39 THE THYROID NODULE 374 HORMONE ERNEST L MAZZAFERRI 402 THYROID HORMONE RESISTANCE KENNETH D BURMAN 428 THYROID FUNCTION TESTS 329 and LEONARD WARTOFSKY 440 THYROID SONOGRAPHY COMPUTED and MARTIN 1 SURKS 454 ABNORMAL THYROID FUNCTION TEST 47 THYROID [books.google.com]
Treatment
During that treatment her menses did not resume. The corticosteroid treatment was complicated by iatrogenic Cushing syndrome and osteonecrosis of the knee. [academic.oup.com]
Until the results from this trial are available, there is still no treatment that has been proved effective by prospective, randomized, controlled study to restore fertility for these women. [utsouthwestern.influuent.utsystem.edu]
Data regarding type of vaccine, number of vaccination, personal, clinical and serological features, as well as response to treatments were analyzed. [ncbi.nlm.nih.gov]
For others, the following treatments are recommended: Hormone therapy Adding calcium and vitamin D supplements to the diet It’s important to talk to your doctor to form a treatment plan designed personally for you. [rockymountainwomenshealthcenter.com]
Prognosis
[…] for prevention of osteoporosis symptomatic control of hot flashes and vaginal dryness prevention of coronary artery disease recommended until after age 50 Assisted reproductive technologies in vitro fertilization with donor oocytes or donor embryos Prognosis [medbullets.com]
GP Information Links Trending Red Flags A-Z GP contract GP Training GP Locums GP Wellbeing Diagnosis and management of premature ovarian insufficiency (POI), including clinical features, investigations to conduct, lifestyle and hormone treatment and prognosis [gponline.com]
Prognosis Sex steroid replacement for women with POI up to the normal age of natural menopause will not only improve symptoms but also reduce the risk of osteoporosis and cardiovascular disease. [patient.info]
Long-term prognosis in galactosaemia: results of a survey of 350 cases. J Inherit Metab Dis 1990; 13(6):802-18 14 Carp HJ, Selmi C, Shoenfeld Y. The autoimmune bases of infertility and pregnancy loss. [glowm.com]
Etiology
There remains, however, a group of POF patients without a known etiology, the so-called "idiopathic" form. An autoimmune etiology is hypothesized for the POF cases with a concomitant Addison's disease and/or oöphoritis. [ncbi.nlm.nih.gov]
We present a case of premature ovarian failure in a 16 year-old girl and discuss the possible etiology, treatment and follow-up in these cases. [ispub.com]
Etiological implicition of autoantibodies to zona pellucida in human female infertility. Am J Reprod Immunol 1992; 28: 104–9. PubMed Google Scholar 15. Smith S, Hosid S. Premature ovarian failure associated with autoantibodies to zona pellucida. [link.springer.com]
Hormone replacement therapy Regardless of the etiology, patients with POI are estrogen deficient. [glowm.com]
Regardless of the etiology, patients with primary ovarian insufficiency are estrogen deficient. [acog.org]
Epidemiology
The next and largest section of the book concerns autoimmune thyroid disease, and authors of these chapters take the reader through the basic epidemiology, genetic and environmental risk factors, immunopathogenesis, and the diagnostic and management aspect [books.google.com]
So to establish a potential correlation, large epidemiological studies are required. [skepticalraptor.com]
[…] menopause) rate of follicle depletion may be accelerated by genetic disorders and toxins to the ovary toxins galactose metabolites chemotherapy/radiation therapy viruses (mumps and CMV) causing oophoritis decreased steroid production without oocyte loss Epidemiology [medbullets.com]
Current research has allowed a greater understanding of the changing epidemiology in POI, genetic f... more Background: Primary ovarian insufficiency (POI) is characterized by 4 to 6 months of amenorrhea and elevated serum FSH and LH in females less than [scinapse.io]
Likewise, each year of delay in age at menopause was found to be associated with a 2.8% increased risk of breast cancer in a collaborative reanalysis of data from 51 epidemiological studies [33]. [journals.plos.org]
Pathophysiology
Published on Apr 26, 2013 pathophysiology of ovarian failure 1. ByProf .Refaat AlshimyAlAzhar University20092009 2. [slideshare.net]
Pathophysiology of impaired ovarian function in galactosaemia. Hum Reprod Update 2006; 12(5):573-84 13 Waggoner DD, Buist NR, Donnell GN. Long-term prognosis in galactosaemia: results of a survey of 350 cases. [glowm.com]
[…] fonti inedite - commento scientifico Vai 2015 Multicavity halloysite-amphiphilic cyclodextrin hybrids for co-delivery of natural drugs into thyroid cancer cells Articolo su rivista Vai 2015 The hypertension of Cushing's syndrome: Controversies in the pathophysiology [unipa.it]
Prevention
Other times there are steps you can take to prevent or delay it. Prevention tips include: Stop smoking immediately. Exercise regularly, which can keep you healthy and prevent obesity. Maintain a healthy weight. [healthline.com]
[…] of osteoporosis symptomatic control of hot flashes and vaginal dryness prevention of coronary artery disease recommended until after age 50 Assisted reproductive technologies in vitro fertilization with donor oocytes or donor embryos Prognosis, Prevention [medbullets.com]
The authors report a case of ovarian failure in a 16 year old girl, most likely due to Savage Syndrome, who started hormonal replacement for normal development of sexual characteres and for osteoporosis prevention. [ispub.com]
Hormone replacement therapy is recommended for treatment of symptoms and prevention of diseases including osteoporosis. [bestpractice.bmj.com]
Most focus on the problems associated with a lack of estrogen, especially as it pertains to preventing osteoporosis. Thus, your doctor will likely want to treat you with hormone therapy. [fibromyalgiatreating.com]