Symptoma

Autoimmune Pancreatitis

AIP

Homepage Rare diseases Search Search for a rare disease Autoimmune pancreatitis Disease definition Autoimmune pancreatitis (AIP) is a rare pancreatic disease characterized by chronic non-alcoholic pancreatitis that presents with abdominal pain, steatorrhea [orpha.net]

Although there can be multisystem involvement, rarely, the cholangitis associated with AIP can present radiologically in a manner similar to that of Klatskin tumour. [ncbi.nlm.nih.gov]

  • Hemophilia A

    A case of acquired hemophilia A (AHA) that developed in a patient with autoimmune pancreatitis (AIP) is presented. A 64-year-old woman was diagnosed with AIP in 2007. The symptoms resolved with prednisolone (PSL). [ncbi.nlm.nih.gov]

  • Subcutaneous Bleeding

    She suddenly presented with subcutaneous bleeding in 2015. Her activated partial thromboplastin time was prolonged (80.0 s). A mixing test showed an inhibitor pattern, factor VIII (FVIII) activity was less than 1%, and FVIII inhibitor was 290 BU/mL. [ncbi.nlm.nih.gov]

  • Scleral Icterus

    AIP is relatively uncommon and is characterized by the following features: Scleral Icterus (yellow eyes), jaundice (yellow skin) which is usually painless, usually without acute attacks of pancreatitis. [en.wikipedia.org]

  • Neck Mass

    Here, we describe a rare case of a 53-year-old male patient who primarily presented with pancreatic body mass, left neck mass and several lumps in his lower lip mimicking pancreatic cancer (PC) and neck metastasis. [ncbi.nlm.nih.gov]

CONCLUSIONS The diagnostic workup of IgG4-RD is complex and usually requires a combination of clinical examination, imaging, and serological analysis. [ncbi.nlm.nih.gov]

Computed tomography (CT), magnetic resonance imaging (MRI), and endoscopic retrograde cholangiopancreatography (ERCP) are usually included in the diagnostic workup. [hematologyandoncology.net]

"Amebic Hepatic Abscesses Workup." Medscape. Mar. 7, 2017. Sood, G. "Acute Liver failure workup." Medscape. June 13, 2017. Tommolino, Emily. "Fatty Liver." Medscape. Apr. 12, 2018. CONTINUE SCROLLING FOR RELATED SLIDESHOW [medicinenet.com]

  • Multilocular Cyst

    The macroscopic examination of the surgical specimen showed whitish solid masses in the head of the pancreas, with multilocular cysts within each mass. [ncbi.nlm.nih.gov]

Data for AIP patients with and those without steroid treatment (steroid treatment vs. wait and see policy or W&S) were then compared. [ncbi.nlm.nih.gov]

Treatment-related complications Since steroids are excellent at controlling disease and inexpensive, any alternative treatment must not only be effective, but also offer a more favorable side effect profile than steroids. [doi.org]

AIP often completely resolves with steroid treatment. [en.wikipedia.org]

BACKGROUND AND AIM: Relapse and diabetes mellitus (DM) are major problems for the prognosis of autoimmune pancreatitis (AIP). We examined the prognosis of type 1 AIP after corticosteroid therapy (CST)-induced remission in terms of relapse and DM. [ncbi.nlm.nih.gov]

Autoimmune pancreatitis should not be overlooked in cases of acute pancreatitis without other obvious etiology. Furthermore, superimposed splenic haemorrhage is a rare but important complication of autoimmune pancreatitis. [ncbi.nlm.nih.gov]

All aspects of AIP—from its definition and epidemiology to its clinical presentation, subtypes, diagnosis, pathophysiology and treatment—are covered in this online course by Julia Mayerle and Georg Beyer. [ueg.eu]

Most of the initial epidemiologic data have come from Japan and Korea. The prevalence was 0.7 per 100,000 patients in a survey of the Japanese population. 3 Further studies are needed to ascertain its incidence and prevalence in the United States. [doi.org]

Author information 1 Division of Gastroenterology, Tohoku University Graduate School of Medicine, Sendai, Japan. 2 Nishimori Clinic, Kochi, Japan. 3 Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University School [ncbi.nlm.nih.gov]

Gastroenterology and Hepatology, Kyoto University Graduate School of Medicine, Kyoto 606-8507, Japan. 2 Laboratory of Extracellular Matrix Biochemistry, Institute for Protein Research, Osaka University, Suita 565-0871, Japan. 3 Department of Healthcare Epidemiology [stm.sciencemag.org]

Early steroid treatment should be considered in patients with uncomplicated AIP to prevent the occlusive vascular complications that are frequently associated with the pathophysiology of this disease process. [ncbi.nlm.nih.gov]

All aspects of AIP—from its definition and epidemiology to its clinical presentation, subtypes, diagnosis, pathophysiology and treatment—are covered in this online course by Julia Mayerle and Georg Beyer. [ueg.eu]

The discovery of these autoantibodies should aid in the understanding of AIP pathophysiology and possibly improve the diagnosis of AIP. [stm.sciencemag.org]

This review provides an update on the diagnosis, pathophysiology and treatment of AIP, with special emphasis on the two subtypes. [academic.oup.com]

It is unresolved whether the titer of autoantibodies directed against amylase α-2A is causally linked to severity of the pathophysiology in patients with AIP and fulminant type 1 diabetes or merely correlates with severity. [diabetes.diabetesjournals.org]

Although the clinical diagnosis of pancreatic masses in patients with IPMN can be occasionally challenging, performing a pathological examination by EUS-FNA may prevent unnecessary pancreatic surgery in cases of possible AIP. [ncbi.nlm.nih.gov]

One must differentiate between the two disorders to prevent unnecessary surgery or delay in corticosteroid therapy. RATES ARE POORLY DEFINED The exact prevalence and incidence of autoimmune pancreatitis remain poorly defined. [doi.org]