Skin eruptions include urticaria, erythema multiforme, eczema, and papulovesicular eruptions. These eruptions typically occur 5 to 8 days prior to menses and subside at the start of menarche. [medscape.com]

The skin eruptions have not returned since the initiation of this therapy. Conclusion: Dermatologists, gynecologists, and obstetricians should be aware of this rare entity. [pubmed.ncbi.nlm.nih.gov]

Although the condition is rare, APD should be included in the differential diagnosis in females with a recurrent, cyclical, or recalcitrant cutaneous eruption. [mdedge.com]

Case of autoimmune progesterone dermatitis presenting as fixed drug eruption. J Dermatol., 36 (2009), pp. 643-645 [6] T. Honda, K. Kabashima, Y. Fujii, M. Katoh, Y. Miyachi. [actasdermo.org]

Case A 25-year-old Asian woman presented with a 4-year history of a recurrent pruritic eruption on her thighs and also on the first and second digits of both hands. [onlinelibrary.wiley.com]

Skin eruptions include urticaria, erythema multiforme, eczema, and papulovesicular eruptions. These eruptions typically occur 5 to 8 days prior to menses and subside at the start of menarche. [medscape.com]

She had long term history of eczema since age of 3 years and had taken regular antihistamines. [anncaserep.com]

[…] with increased progesterone levels during the luteal phase of the menstrual cycle, caused by an immune reaction to endogenous or exogenous progesterone.2,3 Often confused with other dermatoses, cutaneous manifestations of AIPD vary and may present as eczema [emjreviews.com]

A number of different allergic skin conditions, including eczema, urticaria, angioedema, and erythema multiforme, can worsen during the premenstrual time period. [verywellhealth.com]

The clinical symptoms of APD (eczema, urticaria, angioedema, etc.) usually begin 3–10 days before the onset of menstrual flow and end 1–2 days into menses. [link.springer.com]

No other skin lesions were present, and palpation of the cervical, axillary, and inguinal lymph nodes was unremarkable. A repeat 6-mm punch biopsy was performed and she was sent for fasting blood work. Figure 1. [mdedge.com]

The occurrence of skin lesions associated with the introduction of progesterone therapy on two occasions and observations from a clinical examination led us to the diagnosis of AIPD. [emjreviews.com]

The skin lesions resolved completely during treatment. She has been receiving treatment with ulipristal acetate for 9 months. [actasdermo.org]

She was reviewed after 3 months and 5 months following Zoladex injection which showed significant improvement in her skin lesions with no new flare ups. [anncaserep.com]

The diagnostic criteria of APD include recurrent cyclical worsening of skin lesions and symptomatic improvement after inhibition of progesterone secretion by suppression of ovulation. The pathogenesis is unclear. [link.springer.com]

[…] type I or type III; idiopathic angioedema symptoms [47]; and petechiae and purpura on the chest not induced by scratching [50]. [link.springer.com]

Often confused with other dermatoses, cutaneous manifestations of AIPD vary and may present as eczema, folliculitis, stomatitis, mucosal lesions, papulovesicular lesions, papulopustular lesions, vesiculobullous reactions, erythema multiforme, urticaria, angioedema [emjreviews.com]

A number of different allergic skin conditions, including eczema, urticaria, angioedema, and erythema multiforme, can worsen during the premenstrual time period. [verywellhealth.com]

Clinical features of fixed drug,16-18 erythema annulare centrifugum,7 vesicular, bullous, angioedema and anaphylaxis16, 19 have been less commonly reported.20 Mucosal lesions have been commonly reported and occasionally are the sole area involved but [onlinelibrary.wiley.com]

A case of progesterone-induced anaphylaxis, cyclic urticaria/angioedema, and autoimmune dermatitis. J Womens Health. 2011; 20: 643-648. [anncaserep.com]

So, we must first exclude other chronic dermatological conditions that can also have a perimenstrual flare such as acne vulgaris, dermatitis herpetiformis, erythema multiforme, lichen planus, lupus erythematosus and psoriasis [3,6]. [anncaserep.com]

Acne vulgaris, rosacea, and cutaneous lupus erythematosus commonly deteriorate. [hindawi.com]

The use of GnRH causes symptoms of oestrogen depletion such as vaginal dryness, osteoporosis and hot flushes [1,3,5]. [anncaserep.com]

A non-specific or interstitial inflammatory infiltrate was described in 31% of the cases, with 41% having an eosinophilic component and 21% having a neutrophilic component mixed with the predominant lymphocytic infiltrate. [onlinelibrary.wiley.com]