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Autosomal Dominant Coronary Artery Disease 1
Autosomal Dominant CAD 1

Presentation

This is a rare and interesting presentation of an uncommon disorder. Case presentation A 52-year-old Caucasian woman with a known history of autosomal dominant PKD presented with acute onset chest pain lasting over 1 day. [link.springer.com]

In this report, we present the case of a young woman who presented with an acute coronary syndrome and sudden cardiac death due to SCAD, and will present a review of the literature and elaborate on the pathogenesis, therapeutic options, and prognosis. [cathlabdigest.com]

Acronym ADCAD1 Synonyms Coronary artery disease with myocardial infarction Disclaimer Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. [uniprot.org]

This brand-new companion to Braunwald's Heart Disease was designed as a stand-alone reference for physicians treating patients who present with complex, unique challenges, offering the latest information on the use of imaging modalities in diagnosis and [books.google.com]

Workup

There can be more than 20 doctors reviewing every piece of information that has come during a presurgical workup, including the video EEG, the MRI, the PET scan and the neuropsychological testing, to determine if surgery can be offered. [sharecare.com]

[…] location in women, whereas right coronary artery dissection is most common in men. 3–4 Recognition of the dissection can be quite difficult and may require multiple angiographic views or IVUS to confirm the diagnosis. 10,11,24 Treatment and diagnostic workup [cathlabdigest.com]

Treatment

Covers every aspect of evaluation and treatment of patients who suffer from chronic coronary syndromes. [books.google.com]

[…] in Adults (Adult Treatment Panel III). [rarediseases.org]

The major benefit of statin treatment appears to be in primary prevention of fatal coronary disease. [heart.bmj.com]

It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice . [uniprot.org]

J-Comput-Assist-Tomogr. 2001 May-Jun; 25(3): 371-7 Demetriou,-K; H'Maltezou,-E; Pierides,-A-M Familial homozygous hypercholesterolemia: effective long-term treatment with cascade double filtration plasmapheresis. [malattierare.regione.veneto.it]

Prognosis

Highlights new developments concerning epidemiology and prevention, pathophysiology, and clinical findings, as well as laboratory testing, invasive and non-invasive testing, risk stratification, clinical decision-making, and prognosis and management of [books.google.com]

The prognosis appears to be good, if the patient survives the acute phase. [cathlabdigest.com]

Clinical features, management, and prognosis of spontaneous coronary artery dissection. Circulation. 2012;126(5):579–88. CrossRef PubMed Google Scholar 6. Afari ME, Quddus A, Bhattarai M, John AR, Broderick RJ. [link.springer.com]

[…] have any solid enhancing components presence of enhancement of a solid component or septa should raise the possibility of a renal cell carcinoma (RCC) (N.B. infected cysts may peripherally enhance, as do islands of trapped renal tissue) Treatment and prognosis [radiopaedia.org]

CARDIAC INJURY BY RADIOFREQUENCY ENERGY DURING CATHETER ABLATION PREDICTS PROGNOSIS IN ATRIAL FIBRILLATION 16-feb-2015 Mohanty, Sanghamitra; Mohanty, Prasant; Di Biase, Luigi; Trivedi, Chintan; Bai, Rong; Santangeli, Pasquale; Burkhardt, John; Horton, [fair.unifg.it]

Etiology

An important clue to understanding the etiology of CAD is its substantial heritability, which demonstrates that variation in DNA sequence influences risk ( 1 ). [jci.org]

Current status of understanding of the genetic etiology of coronary heart disease. J Postgrad Med 2013;59:30-41 :: Introduction Diseases that are related to the heart and blood vessels are called cardiovascular diseases (CVDs). [jpgmonline.com]

Causes of death during follow-up included cardiovascular complications (38.8%), infectious diseases (16.4%), cancer (10.4%), acute metabolic complications (9.0%), renal failure (3.0%), and other or undetermined etiologies (22.4%). [care.diabetesjournals.org]

Epidemiology

Highlights new developments concerning epidemiology and prevention, pathophysiology, and clinical findings, as well as laboratory testing, invasive and non-invasive testing, risk stratification, clinical decision-making, and prognosis and management of [books.google.com]

Its name is derived from the way the arteries sit on the heart, it can be focal or diffuse and it is the leading cause of death in developing countries where epidemiological studies emphasize dietary and environmental contributions to the disorder. [cags.org.ae]

Relevant External Links for MEF2A Genetic Association Database (GAD) MEF2A Human Genome Epidemiology (HuGE) Navigator MEF2A Atlas of Genetics and Cytogenetics in Oncology and Haematology: MEF2A No data available for Genatlas for MEF2A Gene Transcription [genecards.org]

Epidemiology BS typically presents during adulthood. Although most patients are in their 30’s to 40’s, BS has been reported in patients as young as 2 years of age and as old as 84 years. [geneticheartdisease.org]

Epidemiology In contrast to coronary heart disease having a higher incidence in the elderly, cardiomyopathies can occur at younger ages. [patient.info]

Pathophysiology

Highlights new developments concerning epidemiology and prevention, pathophysiology, and clinical findings, as well as laboratory testing, invasive and non-invasive testing, risk stratification, clinical decision-making, and prognosis and management of [books.google.com]

Genetics and Pathophysiology BS is a genetic disorder. In the inherited form, the mutant genes are passed down from parents to offspring and the syndrome runs in families. [geneticheartdisease.org]

This article gives an overview of hypertension, cardiac complications, and intracranial aneurysms in ADPKD, their pathophysiology, and recent developments in their management. [mdedge.com]

Molecular biology and pathophysiological aspects of plasma cholestery ester transfer protein. Biochim Biophys Acta. 1529: 257-275, 2000. 2) Nagano M et al. [bml.co.jp]

To our knowledge, the role these vasopressin effects play in the pathophysiology of ischemic heart disease has not been evaluated. There are limitations to this study. [care.diabetesjournals.org]

Prevention

For example, according to the CDC Division of Heart Disease and Stroke Prevention (DHDSP) public health departments can work to prevent and control high blood cholesterol and reduce the burden of heart disease and stroke by promoting activities that can [cdc.gov]

Highlights new developments concerning epidemiology and prevention, pathophysiology, and clinical findings, as well as laboratory testing, invasive and non-invasive testing, risk stratification, clinical decision-making, and prognosis and management of [books.google.com]

Read more about preventing CVD. Brain aneurysms An aneurysm is a bulge in a blood vessel caused by a weakness in the blood vessel wall. [nhs.uk]

In FH, primary prevention interventions are more effective in terms of absolute number of prevented deaths than interventions in the setting of secondary prevention. [heart.bmj.com]

This arrhythmia prevents the ventricles from contracting effectively. Without prompt defibrillation (electrical shock), death ensues within a few minutes due to lack of blood flow to the body’s vital organs. [geneticheartdisease.org]

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