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Bacteroides Fragilis


Presentation

  • We present what is to the best of our knowledge the first reported case of B. fragilis endophthalmitis.[ncbi.nlm.nih.gov]
  • We present the case of a 74-year-old otherwise healthy male who presented with fever and right hip pain ten days after a course of intramuscular injections.[ncbi.nlm.nih.gov]
  • To present a patient with monomicrobial anaerobic vertebral osteomyelitis secondary to a previously undescribed source of infection. A 17-year-old boy presented with low back pain 3 months after anal dilatation.[ncbi.nlm.nih.gov]
  • Uncommonly, however, multiple hepatic abscesses caused by anaerobic bacteria are the presenting signs of unsuspected colonic cancer in the absence of liver metastases.[ncbi.nlm.nih.gov]
  • We present a case of a B fragilis bacteraemia and endocarditis caused by seeding of left ventricular thrombus formed secondary to severe left ventricular dysfunction.[ncbi.nlm.nih.gov]
Intravenous Administration
  • The lesions were successfully treated with intravenous administration of antibiotics. Repeated bacterial cultures yielded only Bacteroids fragilis. To our knowledge, this is the first report of pyomyositis due to Bacteroides fragilis.[ncbi.nlm.nih.gov]
Left Ventricular Dysfunction
  • We present a case of a B fragilis bacteraemia and endocarditis caused by seeding of left ventricular thrombus formed secondary to severe left ventricular dysfunction.[ncbi.nlm.nih.gov]
Right Shoulder Pain
  • A 43-year-old Japanese woman was evaluated in the outpatient department for right shoulder pain and fever, which began 5 days earlier. MRI of the right shoulder revealed a high-intensity area deep in the right trapezius muscle.[ncbi.nlm.nih.gov]

Workup

  • We compared the presence of the bft gene in mucosal samples from colorectal neoplasia patients (cases, n 49) to a control group undergoing outpatient colonoscopy for CRC screening or diagnostic workup (controls, n 49).[ncbi.nlm.nih.gov]
Pyuria
  • Anaerobic infections are associated with urinary tract abnormalities and pyuria. The various therapeutic maneuvers that were used to treat the infection are discussed, including antibiotic instillation into the bladder and nephrectomy.[ncbi.nlm.nih.gov]

Treatment

  • Prompt antibiotic treatment and joint drainage are the cornerstones of treatment.[ncbi.nlm.nih.gov]
  • A transcriptionally regulated response was observed using quantitative RT-PCR after metronidazole and hydrogen peroxide treatment, with all three genes being upregulated under stress conditions.[ncbi.nlm.nih.gov]
  • Such infections, although still rare, do exist and tend to complicate treatment.[ncbi.nlm.nih.gov]
  • After treatment with imipenem, pus drained from the pleural cavity yielded an identical isolate that had become highly resistant to imipenem and co-amoxiclav.[ncbi.nlm.nih.gov]
  • We report a 68-year-old Japanese woman who developed pyomyositis caused by Bacteroides fragilis following treatment for multiple myeloma. There are only two cases of pyomyositis associated with multiple myeloma in the literature.[ncbi.nlm.nih.gov]

Prognosis

  • ., Prevotella and Fusobacterium Treatment Metronidazole, clindamycin, and cefoxitin Abscesses should be surgically drained Prognosis, Prevention, and Complications Prognosis worse in immunocompromised and elderly also if there is no access to surgical[step1.medbullets.com]

Etiology

  • We recently diagnosed and treated an unusual case of primary endocarditis due to Bacteroides fragilis, for which no underlying etiology was found.[ncbi.nlm.nih.gov]
  • Defining a microbial etiology for colon cancer has key implications as colon cancer is a major public health problem being the second leading cause of cancer death in the United States in women and men.[grantome.com]
  • Bacterial and viral etiology of childhood diarrhea in Ouagadougou, Burkina Faso. BMC Pediatr. 2013; 13 : 36[ DOI ][ PubMed ] 4. Caceres M, Zhang G, Weintraub A, Nord CE.[jjmicrobiol.com]
  • Anaerobic bacteremia is usually polymicrobial in etiology and has a high death rate ( 4 ). In this case, both bacterial isolates were resistant to the empirical treatment.[wwwnc.cdc.gov]

Epidemiology

  • Critical questions about the epidemiology of chronic, subclinical human colonization with ETBF and its impact on the biology of the colon need to be addressed.[ncbi.nlm.nih.gov]
  • Future epidemiologic and clinical studies are needed to understand the role of ETBF and TXCD in human gastroenteritis.[ncbi.nlm.nih.gov]
  • Strains of Bacteroides fragilis that produce an extracellular 20-kD heat-labile toxin have been epidemiologically associated with diarrheal disease.[ncbi.nlm.nih.gov]
  • It is part of the normal flora of the human colon and is generally commensal , [1] [2] but can cause infection if displaced into the bloodstream or surrounding tissue following surgery, disease, or trauma. [3] Epidemiology and pathogenesis [ edit ] The[en.wikipedia.org]
  • Etiology and epidemiology of diarrhea in children in Hanoi, Vietnam. Int J Infect Dis. 2006; 10 (4): 298-308[ DOI ][ PubMed ] 7. Akhi MT, Shirinzadeh M, Ghotaslou R, Sorous MH, Pirzadeh T, Naghavi Behzad M.[jjmicrobiol.com]
Sex distribution
Age distribution

Pathophysiology

  • The pathophysiology of B. fragilis in spondylodiscitis remains largely unclear because of its rare occurrence.[ncbi.nlm.nih.gov]
  • Pathophysiology Although AGNB perform beneficial functions as part of the GI flora, they are also consummate opportunistic pathogens that can cause serious infections, typically in synergistic infections in combination with other anaerobic as well as[emedicine.medscape.com]

Prevention

  • These observations may help to devise future preventative treatments of premature infants against NEC.[ncbi.nlm.nih.gov]
  • Thus, our data establish that B. fragilis colonization is able to prevent B. henselae damages through PSA.[ncbi.nlm.nih.gov]
  • Current approaches to prevention of colon cancer are cumbersome and underutilized due to their expense and inconvenience.[grantome.com]
  • She made a full recovery and began treatment with a herbal oestrogen derivative to prevent early menopause.[ncbi.nlm.nih.gov]
  • Overexpression of either component was sufficient to prevent lethal disease in Muc2-deficient mice.[ncbi.nlm.nih.gov]

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