Presentation
A singleton pregnancy of longitudinal lie, cephalic presentation and occipito-posterior position was noted. The fetal heart rate was 150 beats/min. [jcgo.org]
Snapshot A 25-year-old man presents to the emergency room for pain in his right lower quadrant. He was found to have perforated appendicitis and was immediately taken to the operating room for emergent laparoscopic appendectomy. [medbullets.com]
Furthermore, I will present mechanistic models of plausible engagement of specific P. gingivalis virulence factors, gingipains and peptidyl arginine deiminase (PPAD) in pathogenesis of first two diseases. [fasebj.org]
If present, the best match for the respective sample will be reported as a presumptive cfiA positive strain. Not for use in clinical diagnostic procedures. [bruker.com]
The results of the present study demonstrate promising therapeutic potential for α‑amylases and pentamidine. [spandidos-publications.com]
Entire Body System
- Wound Infection
Other nonfatal paraparturient mixed infections with bacteroides included amnionitis, endometritis, and wound infections after cesarean section. [journals.lww.com]
Peritonitis -Wound infections -Bite wounds -Dental infections Anaerobes: Epidemiology overview -Need predisposition of the tissue -Need a reduction in tissue oxidation-reduction potential (loss of blood supply, growth of facultative bacteria to use up [quizlet.com]
Head and neck infections dental infection retropharyngeal abscess peritonsillar abscess Aspiration pneumonia Empyema Intra-abdominal infections peritonitis abscess Wound infections Imaging Computed tomography (CT) site involved area ( i.e., abdomen) [medbullets.com]
Definition An anaerobic infection is an infection caused by bacteria (called anaerobes) which cannot grow in the presence of oxygen. Anaerobic bacteria can infect deep wounds, deep tissues, and internal organs where there is little oxygen. [encyclopedia.com]
In settings where anaerobic infections are expected to occur, such as intra-abdominal and wound infections after surgery, proper antimicrobial prophylaxis reduces the chance of such infections. [anaerobicinfections.blogspot.com]
- Sepsis
Morbidity and mortality rates for anaerobic and mixed bacterial sepsis are as high as those for sepsis caused by a single aerobic organism. Anaerobic infections are often complicated by deep-seated tissue necrosis. [msdmanuals.com]
Abdomen - intraperitoneal sepsis such as peritonitis and abscess following perforation of the bowel usually involve several species of anaerobes together with facultative organisms. 5. [virology-online.com]
Infections with B. fragilis can cause severe symptoms including abscess formation and sepsis. [bruker.com]
Nosocomial polymicrobial sepsis with positive Hafnia cultures was diagnosed in four premature neonates with intravenous catheters and parenteral feeding, but without previous abdominal pathology or surgery [ 22 ]. [jcgo.org]
LPS (not endotoxic, doesn't interact with TLR-4) leads to bacteremia without sepsis. -Neuraminidase, hyaluronidase for tissue degradation -Superoxide dismutase (SOD)- resists O2 toxicity. -Enterotoxin (by ETBF) -Zinc metalloprotease. [quizlet.com]
Workup
Microbiology
- Clostridium Perfringens
Cefoxitin is inactive against most clostridial organisms, except Clostridium perfringens. [emedicine.medscape.com]
Localized pneumocephalus caused by Clostridium perfringens meningitis. Br J Neurosurg 1999;13:85-6. [ PUBMED ] 6. Maliwan N. "Spontaneous" pneumocephalus associated with mixed aerobic-anaerobic bacterial meningitis. [jpgmonline.com]
perfringens [C. perfringens] as the cause of diseases classified elsewhere B96.8 Other specified bacterial agents as the cause of diseases classified elsewhere B96.81 Helicobacter pylori [H. pylori] as the cause of diseases classified elsewhere B96.82 [icd10data.com]
Application of serological typing to the investigation of outbreaks of Clostridium perfringens food poisoning, 1970–1978. Journal of Hygiene, Vol. 84, Issue. 03, p. 443. CrossRef Google Scholar Nord, Carl Erik and Norrby, Ragnar 1979. [cambridge.org]
Cefoxitin is relatively inactive against most species of Clostridium (including C. difficile ); C. perfringens is an exception. [anaerobicinfections.blogspot.com]
Treatment
In the empirical treatment of this case, metronidazole has been preferred for treatment of anaerobes; ceftriaxone has been preferred for treatment of other bacteria. [pubs.sciepub.com]
Moxifloxacin was approved by the FDA for the treatment of complicated skin and skin-structure infections and complicated intra-abdominal infections. [emedicine.medscape.com]
Honeybee propolis extract in periodontal treatment: a clinical and microbiological study of propolis in periodontal treatment. Coutinho A. Indian J Dent Res. 2012 Mar-Apr;23(2):294. 16. [passeportsante.net]
Prognosis
[…] and those who were detected with high both IgA and IgG were associated with worst prognosis[40]; Pancreatic cancer patients have suffered poor prognosis, partly for lacking diagnostic and prognostic biomarkers. [wjgnet.com]
[Ph.D. thesis] Valpione, Sara (2017) Biomarkers of prognosis and toxicity for metastatic melanoma patients treated with ipilimumab. [paduaresearch.cab.unipd.it]
Prognosis Complete recovery should be achieved with the appropriate surgery and antibiotic treatment. Untreated or uncontrolled infections can cause severe tissue and bone destruction, which would require plastic surgery to repair. [encyclopedia.com]
Overexpression of long non-coding RNA CCAT1 is a novel biomarker of poor prognosis in patients with breast cancer. Int. J. Clin. Exp. Pathol. 8, 9440–9445. [frontiersin.org]
[…] and neck and periodontal disease has also been reported, suggesting that periodontal disease may be an independent risk factor, with practical implications for prevention, early diagnosis, and treatment, in the search for a possible improvement in the prognosis [mdpi.com]
Etiology
Bacterial and viral etiology of childhood diarrhea in Ouagadougou, Burkina Faso. BMC Pediatr. 2013; 13 : 36[ DOI ][ PubMed ] 4. Caceres M, Zhang G, Weintraub A, Nord CE. [jjmicrobiol.com]
Periodontal disease has a polymicrobial etiology. An extensive combination of bacteria, fungi, and even viruses has been reported to be present simultaneously within infected periodontal sites. [asmscience.org]
The bacterium has been isolated in Turkish women with cervicovaginitis suggesting that etiologic diagnosis of this disease is required to take appropriate preventive and therapeutic measures [ 21 ]. [jcgo.org]
The etiology and pathogenesis of periodontitis. Compend. Contin. Educ. Dent. 23:11-14. ↵ Park, Y., O. Yilmaz, I. Y. Jung, and R. J. Lamont. 2004. [iai.asm.org]
Edmiston CE Jr, Krepel CJ, Seabrook GR and Jochimsen WG (2002) Anaerobic infections in the surgical patient; microbial etiology and therapy. Clinical Infectious Diseases 35: S112–S118. [els.net]
Epidemiology
ISSN: 0950-2688 EISSN: 1469-4409 URL: /core/journals/epidemiology-and-infection × [cambridge.org]
Recent epidemiological studies have revealed that Porphyromonas gingivalis, a major pathogen in periodontal disease, is associated with the development of oral squamous cell carcinoma (OSCC). [pubs.acs.org]
Epidemiology Frequency United StatesThe exact frequency of AGNB infection is difficult to calculate because of inappropriate methods of collection, transportation, and cultivation of specimens. AGNB are more commonly found in chronic infections. [thehealthscience.com]
Recent epidemiological and experimental studies link infectious agents with the development of inflammatory atherosclerosis. [sciencedaily.com]
Etiology and epidemiology of diarrhea in children in Hanoi, Vietnam. Int J Infect Dis. 2006; 10 (4): 298-308[ DOI ][ PubMed ] 7. Akhi MT, Shirinzadeh M, Ghotaslou R, Sorous MH, Pirzadeh T, Naghavi Behzad M. [jjmicrobiol.com]
Pathophysiology
Pathophysiology Although AGNB perform beneficial functions as part of the GI flora, they are also consummate opportunistic pathogens that can cause serious infections, typically in synergistic infections in combination with other anaerobic as well as [thehealthscience.com]
Footnotes Address correspondence to Fusanori Nishimura, Department of Pathophysiology/Periodontal Science, Okayama University Graduate School of Medicine and Dentistry, 2-5-1 Shikata-cho, Okayama 700-8525, Japan. [care.diabetesjournals.org]
The etiopathogenesis of Alzheimer disease Till date, there has not been any appropriate model to reveal the pathophysiology of this disease. [dentalhypotheses.com]
Prevention
Centers for Disease Control and Prevention. Overview of Healthcare-associated MRSA. (Online information). Available online at http://www.cdc.gov/ncidod/dhqp/ar_mrsa.html. Accessed December 2007. Centers for Disease Control and Prevention. [labtestsonline.it]
They are always preceded by gingivitis and, therefore, if the latter is prevented, it is possible to prevent far more serious periodontitis. [mdpi.com]
Strengthening the prevention of periodontal disease : the WHO approach. P.E. Petersen, H. Ogawa. J Periodontol – December 2005. 9. Preventing periodontal disease, JADA, Vol 132, Septembre 2001. 10. The action of thymol on oral bacteria. Shapiro S. [passeportsante.net]
[…] only done by maintaining oral hygiene but also through biomolecular prevention. [dentalhypotheses.com]
Prevention and early therapy of conditions that may lead to anaerobic infection can reduce their rate. [anaerobicinfections.blogspot.com]