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Bartonella Quintana

Rochalimaea Quintana


  • The aim of this report is to illustrate B. quintana endocarditis as an important cause of culture-negative endocarditis that presents challenges in its clinical, diagnostic and therapeutic management.[ncbi.nlm.nih.gov]
  • Author notes * Present address: Division of Medical Sciences, Southern Illinois University School of Medicine, Springfield, Illinois 62708. † Present address: Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland[doi.org]
  • Dr O'Rourke is a veterinary clinical pathologist at the University College Dublin, Dublin, Ireland. Top Mooser H, Weyer F. Experimental infection of Macacus rhesus with Rickettsia quintana (trench fever).[doi.org]
  • Etymology: N.L. fem. adj. arupensis, pertaining to ARUP (Associated Regional and University Pathologists, Inc.) in Salt Lake City, Utah, the laboratory where the type strain was initially characterized. Valid publication: Validation List no. 72.[bacterio.net]
  • Epidemic typhus is another life-threatening louse-borne disease caused by Rickettsia prowazekii and known to occur in conditions of war, famine, refugee camps, cold weather, poverty, or lapses in public health.[ncbi.nlm.nih.gov]
  • Most recently, an epidemic of trench fever erupted in a refugee camp in Burundi [ 8 ]. Wherever it has appeared, disease caused by B. quintana has signaled social disruption and human hardship.[doi.org]
Chronic Infection
  • High antibody titers in chronically infected people could be associated with the presence of endocarditis. 4,18 We believe that B. quintana infections are far more prevalent than is currently recognized.[doi.org]
  • Inhibition of TLR4 breaks the inflammatory loop in autoimmune destructive arthritis. Arthritis Rheum., in press. 1a. Affymetrix. 2003. Expression analysis technical manual. Affymetrix, Santa Clara, CA. 2. Anderson, B. E., and M. A. Neuman. 1997.[doi.org]


  • A laboratory workup was initiated to determine the cause of this clinical presentation and empirical treatment with antibiotics was started.[ncbi.nlm.nih.gov]
  • B. quintana has been retrieved in erythrocytes in large clusters and in erythroblasts. Direct immunofluorescence of blood smears allows a rapid diagnosis.[ncbi.nlm.nih.gov]
  • During asymptomatic period, B. quintana is located in the erythrocytes and has been detected in erythroblasts at the bone marrow (12).[microbewiki.kenyon.edu]
  • Our results suggest that there is a link between alcoholism and infections of B. quintana that may be due to the macrocytosis of erythrocytes.[ncbi.nlm.nih.gov]
Rickettsia Prowazekii
  • Epidemic typhus is another life-threatening louse-borne disease caused by Rickettsia prowazekii and known to occur in conditions of war, famine, refugee camps, cold weather, poverty, or lapses in public health.[ncbi.nlm.nih.gov]
  • prowazekii and B. quintana in lice from patients with fever during an outbreak of epidemic typhus in Burundi. 8 The PCR is rapid and is indicative of active infection, yielding positive results in 3 of 5 lice from recently or currently infected patients[doi.org]
  • Audia JP, Patton MC, Winkler HH (2008) DNA microarray analysis of the heat shock transcriptome of the obligate intracytoplasmic pathogen Rickettsia prowazekii . Appl Environ Microbiol 74: 7809–7812. View Article Google Scholar 12.[journals.plos.org]
Plasmodium Falciparum
  • S84 - 92 ) 19 Effect of vitamin A supplementation on morbidity due to Plasmodium falciparum in young children in Papua New Guinea: a randomised trial , Lancet , 1999 , vol. 354 (pg. 203 - 9 ) 20 Return of trench fever [letter] , Lancet , 1995 , vol. 345[doi.org]
Leptospira Interrogans
  • On the other hand, other LPS species, such as those isolated from Legionella pneumophila, Leptospira interrogans, Helicobacter pylori, and Porphyromonas gingivalis ( 11, 17, 18, 26 ), interact with TLR2 rather than with TLR4.[doi.org]


  • Furthermore, the treatment of the infection has been a challenge for physicians. In this report, we present a 71-year-old patient with Bartonella quintana aortic valve endocarditis from the view of diagnosis and treatment aspects.[ncbi.nlm.nih.gov]


  • Prognosis Usually self-limiting. Trench fever re-infection may occur within 3-6 months because antibodies do not give full protection.[patient.info]


  • B. quintana is now also recognized as an etiological agent of fever and bacteremia, endocarditis, bacillary angiomatosis, and chronic lymphadenopathy.[ncbi.nlm.nih.gov]
  • SUMMARY Bartonella (formerly Rochalimaea) quintana is the etiological agent of trench fever, a disease extensively reported during the World Wars.[cmr.asm.org]


  • Abstract In an epidemiological investigation of trench fever in Japan, we compared the seroprevalence of Bartonella quintana in homeless people and in the general population.[ncbi.nlm.nih.gov]
  • Poverty and louse infestation were the main epidemiological factors associated with B. quintana infections during wartime.[cmr.asm.org]
Sex distribution
Age distribution


  • This particle contains a 14-kb linear DNA segment, but its function in Bartonella pathophysiology is still unknown. In trench fever or B. quintana-induced endocarditis patients, bacillary angiomatosis lesions are also seen.[en.wikipedia.org]
  • In the future, our laboratory-derived B. quintana mutant may play a useful role in angiogenesis models and help to clarify the pathophysiology and treatment of B. quintana infection.[academic.oup.com]


  • The California Department of Public Health in collaboration with San Francisco Project Homeless Connect initiated a program in 2007 to collect lice from the homeless to test for B. quintana and to educate the homeless and their caregivers on prevention[ncbi.nlm.nih.gov]
  • , Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Changping, Beijing 102206, China 3 School of Tropical[mdpi.com]
  • Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions.[doi.org]

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