Growth delays and growth retardation may be seen as affected children age, and final adult height may be shorter than would otherwise be expected (short stature). [rarediseases.org]

[…] to thrive in infancy, EAST syndrome Classic Bartter III (602522) CLCNKB/1p36 ClC-Kb chloride channel DCT Thiazide type Hypomagnesemia, hypocalciuria, EAST syndrome Bartter syndrome with senosorineural deafness IV (606412) BSND/1p31 or CLCNKA- CLCNKB/ [hindawi.com]

Principal clinical features in most of them include early onset polyhydramnios, failure to thrive, prematurity, and nephrocalcinosis. [hindawi.com]

Beginning in infancy, affected individuals often fail to grow and gain weight at the expected rate (failure to thrive). [medlineplus.gov]

Affected infants may fail to grow and gain weight as would be expected based upon age and gender (failure to thrive). [rarediseases.org]

Classic BS presents at a later age with failure to thrive, polyuria, polydipsia, salt craving, and dehydration. History of polyhydramnios and prematurity is absent. Urinary calcium is normal and nephrocalcinosis is usually absent. [indianjnephrol.org]

Antenatal presentation associates polyhydramnios, premature birth, postnatal polyuria complicated by severe dehydration episodes, recurrent vomiting, failure to thrive, growth retardation, and hypercalciuria with nephrocalcinosis (3). [nature.com]

Classic BS presents at a later age with failure to thrive, polyuria, polydipsia, salt craving, and dehydration. History of polyhydramnios and prematurity is absent. Urinary calcium is normal and nephrocalcinosis is usually absent. [indianjnephrol.org]

Growth faltering, dwarfism, polydipsia, and weakness may be present in older children. Mild mental retardation is reported in few patients. [hindawi.com]

Excessive thirst (polydipsia), excessive urination (polyuria), and the need to urinate at night (nocturia) may also occur. Despite excessive fluid intake, frequent urination can lead to dehydration. Some children may crave salt. [rarediseases.org]

Classic Bartter syndrome occurs in infancy or early childhood and is characterized by salt wasting and hypokalemia, leading to polyuria, polydipsia, volume contraction, muscle weakness, growth retardation, and sometimes nephrocalcinosis (4). [cjasn.asnjournals.org]

They lose excess amounts of salt (sodium chloride) in their urine, which leads to dehydration, constipation, and increased urine production (polyuria). [medlineplus.gov]

Additional symptoms that may occur include constipation, vomiting, elevated body temperature, lethargy, and a general feeling of poor health. [rarediseases.org]

Bartter syndrome is also characterized by low levels of potassium in the blood (hypokalemia), which can result in muscle weakness, cramping, and fatigue. [medlineplus.gov]

In some individuals who experience significant electrolyte imbalances, severe complications, such as irregular heartbeats (cardiac arrhythmias) or muscle weakness (paralysis) may develop. [rarediseases.org]

Patients present with fatigue, muscle weakness, and recurrent episodes of tetany in the form of carpopedal spasm. History of polyhydramnios and prematurity is absent. They have hypomagnesemia and hypocalciuria. [indianjnephrol.org]

Classic Bartter syndrome occurs in infancy or early childhood and is characterized by salt wasting and hypokalemia, leading to polyuria, polydipsia, volume contraction, muscle weakness, growth retardation, and sometimes nephrocalcinosis (4). [cjasn.asnjournals.org]

This dilution is not observed in polyhydramnios of nonrenal origin, such as maternal diabetes, esophageal atresia, Pierre Robin syndrome, chloride diarrhea, or digestive tract atresia. [nature.com]

In the antenatal form, it manifests with fetal polyuria, polyhydramnios of early and severe onset, premature delivery, and intrauterine growth restriction. [scielo.conicyt.cl]

The typical features include fetal polyuria, early onset maternal polyhydramnios, intrauterine growth restriction, preterm birth, postnatal polyuria, episodes of dehydration, recurrent vomiting, and failure to thrive [3, 4]. [hindawi.com]

Prenatal manifestations, mainly recurrent polyhydramnios because of fetal polyuria, lead to premature delivery. After birth, polyuria leads to life-threatening dehydration. Prenatal genetic diagnosis needs an index case. [nature.com]

The indomethacin therapy has shown to decrease polyuria, renal salt-wasting, hyperprostaglandinuria, hypercalciuria, and nephrocalcinosis. References 1. Landau D, Shalev H, Ohlay M, Carrni R. [indianjnephrol.org]

Polyuria, hyponatremia, hypokalemia, hyperaldosteronism, and hypercalciuria were initially present. [frontiersin.org]

Lack of satisfactory control may lead to morbidity, growth failure, and renal insufficiency [2, 18, 23]. 8. Prognosis Untreated ABS patients may succumb to dehydration, dyselectrolytemia, and intercurrent infections. [hindawi.com]

Hematological investigation shows hyponatremia, hypokalemia, and hypochloremia with metabolic alkalosis; hypercalciuria with nephrocalcinosis also occurs. [indianjnephrol.org]

Polyuria, hyponatremia, hypokalemia, hyperaldosteronism, and hypercalciuria were initially present. [frontiersin.org]