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Basal Ganglia Lesion

Lesions in the Basal Ganglia


Presentation

  • Abstract This paper describes a diabetic dialysis patient presenting two episodes of symmetric basal ganglia lesions occurring 18 months apart, and discusses the MR imaging findings and the pathogenesis of this condition.[ncbi.nlm.nih.gov]
  • The authors present a more detailed review with rich iconography from the own archive. Copyright 2012 Elsevier Ireland Ltd. All rights reserved.[ncbi.nlm.nih.gov]
  • Mixed hypo- and hyperintensity on T1-weighted MRI could present in the syndrome of acute bilateral basal ganglia lesions in diabetic uremia with hyperglycemia associated dyskinesia.[mdsabstracts.org]
  • […] than a distinct illness Unlike Alzheimer’s, it has a relatively rapid development of dementia It is accompanied by mild extrapyramidal features such as: Masked face Bradykinesia Resting tremor Gait impairment pronounced enough to lead to falls Can also present[brainaacn.org]
  • Patient 1 presented with signal-intensity alterations involving the dorsal striatum and the cerebellum. However, none of the typical lesions usually associated with WE were detected in patient 1.[ajnr.org]
Tremor
  • ., extrapyramidal) injury involve the following involuntary movement disorders: Parkinsonism – combination of resting tremor, rigidity, bradykinesia/akinesia, and postural abnormalities Athetosis – slow continuous, writhing movements of the fingers, hands[brainaacn.org]
  • This distinguishes it from other disorders involving tremor in which the tremor persists during movement (essential tremor) or is specifically associated with movement (intention tremor in cerebellar disorders).[courses.washington.edu]
  • […] thalamus and cortex rigidity, increased tone, slow reduced movements, bradykinesia/hypokinesia, stooped posture, resting tremor are all symptoms of....[memorize.com]
  • Wilson’s Disease (Hepatolenticular degeneration): As the name suggests – lenticular dengeneration due to copper accumulation Lenticular or lentiform nucleus Putamen Globus pallidus Dystonia and Tremor are the most common hyperkinetic movement disorders[epomedicine.com]
Stroke
  • Prognosis of Basal Ganglia Stroke Approximately 33% of all stroke cases are deadly.[healthfixit.com]
  • In addition, patients with hemorrhagic stroke are usually more affected than those with ischemic stroke, which warrants further study with homogeneous group of patients.[omicsonline.org]
  • […] indirect pathway) in huntington's disease there is increased output of... thalamus and cortex (hyperkinesia) which basal ganglia disorder is characterized by wild flailing movement of the arm and leg of one side... hemiballismus hemiballismus is... a stroke[memorize.com]
  • Case of Ferumoxytol (Feraheme ) Prompting Critical Modification to Our Patient Prebreast Magnetic Resonance Imaging Questionnaire Naziya Samreen, Asha A Bhatt, James Glockner, Christine U Lee J Clin Imaging Sci 9 (6) 1-3 (28 March 2019) Case report: Stroke[clinicalimagingscience.org]
  • Such conditions include: Carbon monoxide poisoning Drug overdose Head injury Infection Liver disease Metabolic problems Multiple sclerosis (MS) Poisoning with copper, manganese, or other heavy metals Stroke Tumors A common cause of these findings is chronic[medlineplus.gov]
Chorea
  • In 39 patients, chorea had ameliorated completely. The remaining 14 cases showed some improvement during the follow-up period. The chorea recurred in seven patients. CONCLUSION: C-H-BG is a benign disorder affecting the elderly.[ncbi.nlm.nih.gov]
  • Hyperglycemia associated unilateral predominant chorea could demonstrate with symmetrical T1–hyperintense lesions in basal ganglia on brain MRI.[mdsabstracts.org]
  • […] injury involve the following involuntary movement disorders: Parkinsonism – combination of resting tremor, rigidity, bradykinesia/akinesia, and postural abnormalities Athetosis – slow continuous, writhing movements of the fingers, hands, face, and throat Chorea[brainaacn.org]
  • "Sydenham Chorea Information Page" Saint Vitus Dance, Rheumatic Encephalitis from the National Institute of Neurological Disorders and Stroke. Accessed April 26, 2008 a b Sydenham's Chorea Symptoms .Accessed September 24, 2009.[en.wikipedia.org]
  • […] and variable location on the body Huntington’s chorea – due to excessive CAG (trinucelotide) repeats on chromosome 4 3.[epomedicine.com]
Dystonia
  • OBJECTIVE: To assess the efficacy of epidural motor cortex stimulation (MCS) on dystonia, spasticity, pain, and quality of life in patients with dystonia secondary to a focal basal ganglia (BG) lesion.[ncbi.nlm.nih.gov]
  • Truncal dyskinesia, right side predominant limbs chorea, cervical dystonia and abnormal gait gradually developed. Laboratory data showed hyperglycemia (sugar: 436 mg/dl).[mdsabstracts.org]
  • G24.01 Drug induced subacute dyskinesia G24.02 Drug induced acute dystonia G24.09 Other drug induced dystonia G24.1 Genetic torsion dystonia G24.2 Idiopathic nonfamilial dystonia G24.3 Spasmodic torticollis G24.4 Idiopathic orofacial dystonia Reimbursement[icd10data.com]
  • Dystonia [ edit ] Dystonia is a hyperkinetic movement disorder that is characterized by involuntary movement and the slowing of intentional movement.[en.wikipedia.org]
  • Describe - Choreiform, Athetoid, Ballismus, Dystonia, Dyskinesias, Hyperkinetic Disorders (cont.)[quizlet.com]
Resting Tremor
  • ., extrapyramidal) injury involve the following involuntary movement disorders: Parkinsonism – combination of resting tremor, rigidity, bradykinesia/akinesia, and postural abnormalities Athetosis – slow continuous, writhing movements of the fingers, hands[brainaacn.org]
  • […] thalamus and cortex rigidity, increased tone, slow reduced movements, bradykinesia/hypokinesia, stooped posture, resting tremor are all symptoms of....[memorize.com]
  • Symptoms The disease is diagnosed by observing a set of characteristic symptoms that affect motor control: resting tremor, bradykinesia, and hypertonia. Resting tremor is an oscillating movement that occurs when the patient is trying to be still.[courses.washington.edu]

Treatment

  • Results : A 32-year-old lady with history of type II diabetic mellitus, hypertension, old myocardial infarction post treatment of coronary artery bypass grafting, end stage renal disease under peritoneal dialysis for years.[mdsabstracts.org]
  • Lancet Oncology 5, 1-8, 2009 4) Serizawa T, Iuchi T, Ono J et al: Gamma knife treatment for multiple metastatic brain tumors compared with whole-brain radiation therapy.[chiba-neurosurgery.jp]
  • Presently, treatment consists of calcium supplementation and the use of vitamin D analogs, but PTH replacement is under investigation. Treatment is important to prevent progression of BGC. Competing interests None declared. References 1.[bcmj.org]
  • It does not provide medical advice, diagnosis, or treatment. This content is not intended to be a substitute for professional medical advice, diagnosis, or treatment.[multiplesclerosisnewstoday.com]
  • Treatment Approaches for Overactivity of the Basal Ganglia Treatments for overactivity of the basal ganglia are essentially those for anxiety. Take a step back and pay attention to your thinking.[drlaurendeville.com]

Prognosis

  • Prognosis of Basal Ganglia Stroke Approximately 33% of all stroke cases are deadly.[healthfixit.com]
  • - Secondary progressive disease - gradual neurological deterioration with or without relapses - Primary progressive disease - nearly continuous neurological deterioration from onset of symptoms -worst prognosis - Treatment - acute episodes with corticosteroids[quizlet.com]
  • […] symmetric signal-intensity alterations in the mammillary bodies, medial thalami, tectal plate, and periaqueductal area. 1 – 4 Selective involvement of the putamen has been reported only in the pediatric population and is considered an indicator of poor prognosis[ajnr.org]

Epidemiology

  • Pagina 15 - Schiffer RB, Babigian HM: Behavioral disorders in multiple sclerosis, temporal lobe epilepsy, and amyotrophic lateral sclerosis: an epidemiologic study. ‎[books.google.it]
Sex distribution
Age distribution

Pathophysiology

  • This research topic aims to bring together the most recent advances related to the pathophysiology of the basal ganglia and movement disorders.[frontiersin.org]
  • Wichmann T and DeLong MR (1996) Functional and pathophysiological models of the BG. Current Opinion in Neurobiology 6: 751–758.[els.net]
  • "Functional and pathophysiological models of the basal ganglia". Curr. Opin. Neurobiol. 6 (6): 751–8. doi : 10.1016/S0959-4388(96)80024-9. PMID 9000030. Curtis AR, Fey C, Morris CM, et al. (August 2001).[en.wikipedia.org]

Prevention

  • Prevention of Stroke Any forms of CVA are dangerous to face. The best way to never experience stroke is prevention. In order to do that, risk factors (as enumerated in the earlier section of this article) to stroke should be eliminated.[healthfixit.com]
  • Treatment is important to prevent progression of BGC. Competing interests None declared. References 1. Rumboldt Z, Castillo M, Huang B, et al. (eds). Brain imaging with MRI and CT: An image pattern approach.[bcmj.org]
  • Or if you have migraines, you can take medicine to both prevent and treat them. If you are anxious or depressed, see your doctor. There are medicines to help with mood issues.[webmd.com]
  • For motor skills, the basal ganglia are critical in preventing muscular overreactivity. In MS, the basal ganglia don’t deliver neurochemical signals with fluidity.[multiplesclerosisnewstoday.com]

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