Presentation
Similarly, the present report details a patient with nonketotic hyperglycemia and a hyperdense basal ganglion lesion with an unusual clinical presentation. [ceemjournal.org]
The presenting history is often only a few months and most patients present with a space occupying lesion or lesions producing local deficits. [thamburaj.com]
The motor system is present at all levels of the nervous system. [csuchico.edu]
This report is based on analysis of seven patients with brain tumours, who had MDs either as their principal presenting feature or these were important part of clinical presentation. Diagnosis was made by computed tomography (CT). [neurologyindia.com]
The authors present a more detailed review with rich iconography from the own archive. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved. [ncbi.nlm.nih.gov]
Entire Body System
- Weight Loss
loss) PML Rapid neurologic decline (hemiplegia, visual field defects, ataxia, aphasia) HIV Encephalopathy Progressive memory loss, depression, movement disorders CMV encephalitis Confusion, focal deficits Laboratory tests Blood : Anti-toxoplasma IgG [learningradiology.com]
Patients present with confusion, memory loss, hemiparesis, aphasia, and seizures. Most patients have constitutional symptoms such as fever, night sweats, and weight loss. Epstein-Barr virus DNA may be found in the cerebrospinal fluid. [aafp.org]
- Pallor
Periventricular caps are hyperintense regions around the anterior and posterior pole of the lateral ventricles and are associated with myelin pallor and dilated perivascular spaces. [radiologyassistant.nl]
- Cerebral Palsy
Chorea and athetosis are commonly due to long-term exposure to neuroleptics, excess of dopamine stimulating medicine, Huntington's disease or the choreoathetotic variety of cerebral palsy. [dartmouth.edu]
Gastrointestinal
- Muscle Rigidity
In general, symptoms vary and may include: Movement changes, such as involuntary or slowed movements Increased muscle tone Muscle spasms and muscle rigidity Problems finding words Tremor Uncontrollable, repeated movements, speech, or cries (tics) Walking [medlineplus.gov]
Facial muscle rigidity can also partly or completely account for the "masked facies." [dartmouth.edu]
Eyes
- Lacrimation
[…] rhabdomyosarcoma (child), metastasis (child: neuroblastoma to bone; adult: breast, lung, prostate, melanoma to uvea, rectus muscles, bone) Metastasis to bony orbit Invasion by adjacent primary tumor: paranasal sinus or nasal SCC, sphenoid wing meningioma Lacrimal [quizlet.com]
"clusters" up to several times per day for a period of one or more months before going into "remission" for months or years; diagnosis requires one or more of the following autonomic abnormalities ipsilateral to the headache: conjunctival injection, lacrimation [strokecenter.org]
Psychiatrical
- Anxiety Disorder
"Meta-analytical comparison of voxel-based morphometry studies in obsessive-compulsive disorder vs other anxiety disorders". Archives of General Psychiatry. 67 (7): 701–711. doi : 10.1001/archgenpsychiatry.2010.70. [en.wikipedia.org]
- Fear
[…] disorder in which in the daily sleep/wake cycle is delayed with respect to clock time such that sleep occurs well after the conventional bedtime; common in young adults delirium abnormal mental state characterized by disorientation, inattention, confusion, fear [strokecenter.org]
Neurologic
- Stroke
Hemorrhagic stroke This less common type of stroke accounts for about 40 percent of all stroke deaths, according to the National Stroke Association. [medicalnewstoday.com]
This is why basal ganglia strokes are often hemorrhagic strokes as well. About 13 percent of all strokes are hemorrhagic strokes. An ischemic stroke can also affect the basal ganglia. [healthline.com]
Identification of nonischemic stroke mimics among 411 code strokes at the university of california, san diego, stroke center. J Stroke Cerebrovasc Dis. 2008;17:23-25. Libman RB, Wirkowski E, Alvir J, Rao TH. [appliedradiology.com]
Collaborative Meta-Analysis of Randomised Trials of Antiplatelet Therapy for Prevention of Death, Myocardial Infarction, and Stroke in High Risk Patients. [books.google.es]
Upper motor neuron disorders typically arise from such causes as stroke, tumors, and blunt trauma. [nba.uth.tmc.edu]
- Tremor
The tremor has been erroneously considered a tremor at rest, but actually it is a tremor of postural or resting muscle tension. [dartmouth.edu]
For example, the thumb and forefingers will move back-and-forth against each other in a characteristic tremor called “pill-rolling tremor.” The tremor stops when the body part engages in active movement. [nba.uth.tmc.edu]
Scott M : Parkinsonism-like tremor and cog wheel rigidity in child secondary to massive ependymoma of the frontal lobe and caudate nucleus : prefrontal lobectomy with cassation of tremor and rigidity. Arch Neurol Psychiatry 1974; 57 : 649-654. 16. [neurologyindia.com]
In general, symptoms vary and may include: Movement changes, such as involuntary or slowed movements Increased muscle tone Muscle spasms and muscle rigidity Problems finding words Tremor Uncontrollable, repeated movements, speech, or cries (tics) Walking [medlineplus.gov]
- Chorea
This book describes in detail the latest clinical and etiological information regarding chorea. Management strategies, pathophysiology, and associated medical and psychiatric problems associated with chorea are also addressed. [books.google.de]
The model for choreiform disorders is Huntington's chorea. [dartmouth.edu]
Types of Hyperkinesia Chorea: Huntington’s chorea and Sydenham chorea. Wilson’s disease. Athetosis. Dystonia. Ballismus/Hemiballismus. Tardive dyskinesia. [drnajeeblectures.com]
Krauss et al [7] reported dystonia and chorea in most of their patients of thalamic tumours with MDs. [neurologyindia.com]
Chorea This answer is INCORRECT. Chorea is an involuntary, abnormal movement. C. Tremors D. Rigidity E. Ballismus All of the following are examples of dyskinesia EXCEPT: A. Athetosis B. Chorea C. Tremors This answer is INCORRECT. [nba.uth.tmc.edu]
- Dystonia
CONCLUSION These cases emphasise the importance of the GP, particularly its internal segment, in the pathophysiology of dystonia. globus pallidus lesions basal ganglia dystonia Statistics from Altmetric.com globus pallidus lesions basal ganglia dystonia [jnnp.bmj.com]
G24.01 Drug induced subacute dyskinesia G24.02 Drug induced acute dystonia G24.09 Other drug induced dystonia G24.1 Genetic torsion dystonia G24.2 Idiopathic nonfamilial dystonia G24.3 Spasmodic torticollis G24.4 Idiopathic orofacial dystonia Reimbursement [icd10data.com]
Dystonias With one exception, the dystonias are uncommon disorders. They are characterized by torsion spasms of the limbs, trunk, and neck. [dartmouth.edu]
Moreover, the patient’s clinical symptoms were relatively nonspecific, although his slowly progressing hemiparesis and mental retardation in addition to dystonia are distinct features of idiopathic torsion dystonia. [ajnr.org]
• CLINICAL FEATURES : dysarthria, dystonia, tremors, ataxia, Parkinsonian symptoms, and psychiatric problems. [slideshare.net]
- Excitement
Thus, the loss of the nigrostriatal dopaminergic pathway upsets the fine balance of excitation and inhibition in the basal ganglia and reduces the excitation of motor cortex. [nba.uth.tmc.edu]
Another shorter indirect pathway has been proposed, which involves cortical excitation of the subthalamic nucleus resulting in direct excitation of the GPe, and inhibition of the thalamus. [en.wikipedia.org]
Therefore, when the tonic activity of dopamine is lost, the motor and premotor cortex are less excitable and the patient is less mobile, with slower responses and less spontaneous movement. [dartmouth.edu]
[…] the head being held down and pointed toward the floor paralysis loss of motor function in a body part paramedian pontine reticular formation (PPRF) collection of premotor neurons located in or near the abducens nucleus that drive horizontal gaze when excited [strokecenter.org]
Treatment
They perform a major role in facilitating the diagnosis, understanding the mechanisms of symptoms, and monitoring the effect of new treatments. [books.google.com]
Complication during treatment if any : None. Follow up C.T. [pbhrfindia.org]
Pulmonary arteriovenous malformations: evaluation with CT of the chest before and after treatment. Seite 233 - Magnetic resonance imaging in planning limb-salvage surgery for primary malignant tumors of bone. [books.google.de]
There is no effective treatment other than palliation. [dartmouth.edu]
Ueki K, Tanaka R (1980) Treatments and prognosis of pineal tumors — Experience of 110 cases. Neurol Med Chir (Tokyo) 20:1–26 (in Jpn) Google Scholar 7. [springerlink.com]
Prognosis
DAI and delayed (within 48 hours) increase in hematoma have been implicated for poor prognosis in these patients 1 8. [ispub.com]
Ueki K, Tanaka R (1980) Treatments and prognosis of pineal tumors — Experience of 110 cases. Neurol Med Chir (Tokyo) 20:1–26 (in Jpn) Google Scholar 7. [springerlink.com]
In light of these observations and the poor prognosis despite radiotherapy, chemotherapy is being increasingly used. [thamburaj.com]
Prognosis of CNS GCTs. In: Sawamura Y, Shirato H, de Tribolet N, eds. Intracranial germ cell tumors Vienna: Springer-Verlag; 1998 : 155 –168 Received April 24, 2004. Accepted after revision July 30, 2004. [ajnr.org]
Etiology
This book describes in detail the latest clinical and etiological information regarding chorea. Management strategies, pathophysiology, and associated medical and psychiatric problems associated with chorea are also addressed. [books.google.de]
Etiology Diseases causing multiple ring-enhancing lesions of the brain are infectious, neoplastic, inflammatory or vascular in origin. [bioline.org.br]
Fungal granulomas frequently reveal a ring-like or nodular enhancement on MRI and cannot be distinguished from granuloma of other etiology. [jpgmonline.com]
As such, diagnosis of the underlying etiology may be difficult to achieve at imaging. [em-consulte.com]
Local inflammatory responses, vasculitis, and autoimmune mechanisms have been implicated in the etiology of Lyme neuroborreliosis. [canlyme.com]
Pathophysiology
Management strategies, pathophysiology, and associated medical and psychiatric problems associated with chorea are also addressed. [books.google.de]
Coverage ranges through the contributions of MR, the variety of techniques available, diagnosis and differential diagnosis, MR as a predictor of the clinical course, MR views of pathophysiology, and finally monitoring new treatment efficacy. [books.google.com]
CONCLUSION These cases emphasise the importance of the GP, particularly its internal segment, in the pathophysiology of dystonia. globus pallidus lesions basal ganglia dystonia Statistics from Altmetric.com globus pallidus lesions basal ganglia dystonia [jnnp.bmj.com]
Wong ST, Yuen SC, Fong D (2009) Pathophysiological mechanism of ipsilateral cerebral and brainstem hemiatrophy in basal ganglia germ cell tumors: case report. Childs Nerv Syst 25:693–699 PubMed CrossRef Google Scholar 15. [link.springer.com]
Further, functional studies are needed which will provide deeper insights into the pathophysiological processes underlying the generation of MDs in patients with brain tumours. 1. [neurologyindia.com]
Prevention
Collaborative Meta-Analysis of Randomised Trials of Antiplatelet Therapy for Prevention of Death, Myocardial Infarction, and Stroke in High Risk Patients. [books.google.es]
Risk factors People at higher risk of stroke might wish to take preventative measures to minimize their risk. Being aware of the risk factors is, therefore, beneficial. [medicalnewstoday.com]
They are unable to make the appropriate kinetic-postural adjustment necessary to prevent them from falling. [dartmouth.edu]
Or if you have migraines, you can take medicine to both prevent and treat them. If you are anxious or depressed, see your doctor. There are medicines to help with mood issues. [webmd.com]
Early diagnosis is important not only to prevent further neurologic deficit but also, by allowing a reduction in radiation field and/or dose, to obtain a reduction in posttreatment sequelae and preservation of neurocognitive function, while preventing [ajnr.org]