Symptoma

Bazex Syndrome

BDCS

We present evidence to justify costs of therapy for insurance purposes. [ncbi.nlm.nih.gov]

  • Cervical Lymphadenopathy

    This article describes Bazex syndrome in a 56-year-old woman who presented with bilateral cervical lymphadenopathy and a mass at the base of her tongue. [ncbi.nlm.nih.gov]

    Six weeks later, the patient developed bilateral cervical lymphadenopathy. [mdedge.com]

  • Lymphadenopathy

    This article describes Bazex syndrome in a 56-year-old woman who presented with bilateral cervical lymphadenopathy and a mass at the base of her tongue. [ncbi.nlm.nih.gov]

    Six weeks later, the patient developed bilateral cervical lymphadenopathy. [mdedge.com]

    Aguirre-Negrete Syndrome Hernandez Fragoso Syndrome herpes zoster oticus Herrmann Syndrome Hersh Podruch Weisskopk Syndrome Hhhh Syndrome HID Syndrome high myopia-sensorineural deafness syndrome high pressure neurological syndrome Hirata disease histiocytosis-lymphadenopathy [rgd.mcw.edu]

  • Severe Pain

    She suffered severe pain in the fingers and toes and experienced some symptomatic relief with psoralen ultraviolet A therapy. [ncbi.nlm.nih.gov]

  • Shivering

    Case presentation A 60-year-old woman presented with acute upper abdominal pain, fever, nausea and shivering as well as elevated liver and pancreatic enzymes. [bmccancer.biomedcentral.com]

  • Respiratory Insufficiency

    Insufficiency Syndrome Pub Type(s) Case Reports English Abstract Journal Article Language spa PubMed ID 17257564 TY - JOUR T1 - [Pulmonary adenocarcinoma and Bazex syndrome (paraneoplastic acrokeratosis)]. [unboundmedicine.com]

  • Hematochezia

    Colonoscopy was performed because of hematochezia, and it revealed an early colon cancer. After the resection of the cancer, the skin lesions began to fall off dramatically. [ncbi.nlm.nih.gov]

  • Upper Abdominal Pain

    Case presentation A 60-year-old woman presented with acute upper abdominal pain, fever, nausea and shivering as well as elevated liver and pancreatic enzymes. [bmccancer.biomedcentral.com]

  • Abdominal Pain

    Case presentation A 60-year-old woman presented with acute upper abdominal pain, fever, nausea and shivering as well as elevated liver and pancreatic enzymes. [bmccancer.biomedcentral.com]

  • Anhidrosis

    Anhidrosis (inability to sweat) of the face and head may also occur. In adulthood, around 20-30 years old, basal cell carcinomas begin to appear on the face. These are similar to the tumours of Gorlin syndrome. [dermnetnz.org]

  • Sparse Eyebrows

    Eyebrows found to be sparse Click here to view Figure 3: Closer view of the hyperpigmented papules showing rolling border and central ulceration Click here to view Figure 7: Multiple facial milia, characteristic appearance of nose and sparse eyebrows [ijdvl.com]

  • Sparse to No Eyebrows

    The patient had camouflaged the sparseness of the eyebrows with a black pencil [Figure 7]. There was a single 0.5 cm 0.5 cm hyperpigmented papule below her left eye, [Figure 7] which had appeared 5 years back. [ijdvl.com]

  • Long Thin Nose

    All three cases had long thin noses, with prominent columella and hypoplastic nasal alae. There was no evidence of acral erythema or palmoplantar pits in any of the patients. Skeletal abnormalities were ruled out with normal skiagrams. [ijdvl.com]

  • Incontinence

    […] always of epidermal and never of mesodermal origin, possible histopathological changes including the presence of necrotic foci, scattered vacuolar degeneration of basal cells, cytoplasmic eosinophilia and vacuolization of keratinocytes and pigmentary incontinence [bmccancer.biomedcentral.com]

Treatment modalities including topical and systemic corticosteroids, salicylic acid, topical vitamin D analogues, etretinate and PUVA therapy are often ineffective. [ncbi.nlm.nih.gov]

An early diagnosis may improve the patient's prognosis substantially. 2017 European Academy of Dermatology and Venereology. [ncbi.nlm.nih.gov]

[…] made on the basis of radiological (computerized) images, blood tests, and tissue biopsies The main treatment involves attempting to resolve the underlying cancer, and the use of topical corticosteroid creams to help control and treat skin lesions The prognosis [dovemed.com]

In most reported cases of acrokeratosis paraneoplastica, cervical lymph node metastases are present at the time of diagnosis, usually indicating a poor prognosis. [4] Morbidity and mortality in acrokeratosis paraneoplastica are related directly to the [emedicine.medscape.com]

Bazex syndrome). ( 29036561 ) Dabas G....Radotra B.D. 2018 4 Acrokeratosis Neoplastica (Bazex Syndrome) ( 29083711 ) Pulickal J.K....Kaliyadan F. 2017 5 Acrokeratosis paraneoplastica (Bazex syndrome) - a systematic review on risk factors, diagnosis, prognosis [malacards.org]

Moreover, etiological therapy against underlying malignancy is essential for treating paraneoplastic Bazex syndrome. [ncbi.nlm.nih.gov]

Etiology The etiology is unknown. Proposed mechanisms include reaction to secreted epidermal growth factors, tumor specific antibodies that react to the skin basement membrane, or zinc deficiency. [dermatologyadvisor.com]

Etiology The gene has been mapped to the long arm of the X chromosome, within the Xq24-q27.1 region. UBE2A (Xq24), encoding a protein involved in repair of UV-damaged DNA, has been proposed as a candidate gene. [rarediseases.info.nih.gov]

Acrokeratosis paraneoplastica (Bazex syndrome) presenting in a patient with metastatic breast carcinoma: possible etiologic role of zinc. J Cutan Med Surg. 2007 Mar-Apr. 11(2):78-83. [Medline]. [emedicine.medscape.com]

Epidemiology So far, 143 cases have been reported, mostly from France and Belgium. Clinical description The disease manifests during the neonatal period or during infancy. [rarediseases.info.nih.gov]

Proposed mechanisms include cross-reactivity between skin and tumor antigens, the action of tumor-produced growth factors, and even zinc deficiency. [1, 2] Epidemiology Frequency Approximately 140 cases of acrokeratosis paraneoplastica have been reported [emedicine.medscape.com]

The BJD has distinct sections for clinical trials, guidelines, translational research, epidemiology and qualitative and outcomes research. [onlinelibrary.wiley.com]

[…] dermatofibroma Member Rated 0 Patient case no. 338 Date added 01 January 1990 Patient details Age --Undetermined-- Localisation --Undetermined-- Primary Lesions Papule / hyperpigmented Pathophysiology tumors and proliferative diseases / connective tissue [dermquest.com]

Pathophysiology Pathophysiology consists of keratinocyte proliferation with resultant parakeratosis and acanthosis. [dermatologyadvisor.com]

Pathophysiology The pathophysiology of acrokeratosis paraneoplastica is not understood. [emedicine.medscape.com]

We report that BDCS is a novel ciliopathy and the first case of a skin cancer ciliopathy, where ARP-T1 plays a critical role to prevent pathogenesis. [biorxiv.org]

[…] minus' sign Virchow -triad Use Parentheses water AND (cup OR glass) Add an asterisk (*) at end of a word to include word stems Neuro* will search for Neurology, Neuroscientist, Neurological, and so on Use quotes to search for an exact phrase "primary prevention [read.qxmd.com]

Neoplastica and by the response of the affected individual to treatment Please find comprehensive information on Acrokeratosis Neoplastica regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention [dovemed.com]

Sun protection is essential to reduce the number of skin cancers developing but even total protection will not prevent occurrence of basal cell carcinomas in these patients. [xpertdox.com]

Sun protection is vital to reduce the number of skin cancers developing but even complete protection will not prevent all basal cell carcinomas in patients with Bazex-Dupre-Christol syndrome. See smartphone apps to check your skin. [dermnetnz.org]

Images