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Becker Nevus Syndrome

NCM


Presentation

  • We present two clinical cases of Becker nevus syndrome with thoracic nevus and ipsilateral breast hypoplasia treated with lipofilling alone (fat grafting).[ncbi.nlm.nih.gov]
  • A 12-year-old boy presented a brown lesion on the anterior aspect of the chest that had been present since 6 months of age. The lesion had a hairy surface and biopsy confirmed the diagnosis of Becker nevus.[kundoc.com]
  • Becker nevus syndrome presented with ipsilateral breast hypoplasia. Indian J Dermatol 2014;59:634 How to cite this URL: Pektas SD, Akoglu G, Metin A, Adiyaman NS, Demirseren ME. Becker nevus syndrome presented with ipsilateral breast hypoplasia.[e-ijd.org]
Relapsing Polychondritis
  • polychondritis 733 219 Rhinophyma 737 220 Rocky Mountain spotted fever and other rickettsial infections 739 221 Rosacea 744 222 Sarcoidosis 752 223 Scabies 757 224 Scleredema 761 225 Scleroderma 764 226 Sebaceous hyperplasia 769 227 Seborrheic eczema[books.google.com]
Myxedema
  • Polymorphic light eruption 643 197 Porokeratoses 646 198 Porphyria cutanea tarda 650 199 Port wine stain nevus flammeus 653 200 Postinflammatory hyperpigmentation and other disorders of hyperpigmentation 658 201 Pregnancy dermatoses 662 202 Pretibial myxedema[books.google.com]
Mitral Valve Prolapse
  • Unusual skeletal abnormalities (depressed nasal bridge, long slender digits, crowding of lateral toes, valgus deformity of first metatarsophalangeal joint), mental retardation, and cardiac defects (mitral valve prolapse). 3.[e-ijd.org]
Cyanosis
  • Seite xvi - The Rombo syndrome: a familial disorder with vermiculate atrophoderma, milia, hypotrichosis, trichoepitheliomas, basal cell carcinomas and peripheral vasodilation with cyanosis. Acta Derm Venereol. ‎[books.google.de]
Xanthoma
  • […] disease 834 247 Trichotillomania 836 248 Tuberculosis and tuberculids 838 249 Urticaria and angioedema 840 250 Varicella 844 rubella roseola rubeola and enteroviruses 848 252 Viral warts 852 253 Vitiligo 859 254 Vulvodynia 864 255 Wells syndrome 868 256 Xanthomas[books.google.com]
Yellow Nails
Ataxia
  • AJ, JR. (1992) A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in Ataxia-Telangiectasia. ‎ Seite 136 - R. (1997).[books.google.de]

Workup

Staphylococcus Aureus
  • aureus and PantonValentine leukocidin Staphylococcus aureus infections 499 154 Miliaria 505 155 Molluscum contagiosum 508 156 Morphea 512 157 Mucoceles 515 158 Mucous membrane pemphigoid 517 eumycetoma and actinomycetoma 522 160 Mycobacterial atypical[books.google.com]

Treatment

  • Treatment Options Table I. Treatment options for Becker’as nevus Table I.[dermatologyadvisor.com]
  • We believe that the lipofilling technique is a natural and valuable treatment option for thoracic anomalies in Becker nevus syndrome with a major impact on patient's quality of life.[ncbi.nlm.nih.gov]
  • You may also want to contact a university or tertiary medical center in your area, because these centers tend to see more complex cases and have the latest technology and treatments.[rarediseases.info.nih.gov]

Prognosis

  • (Outcomes/Resolutions) The prognosis of Becker’s Nevus is excellent on its complete excision and removal Since, these are benign conditions, the prognosis is generally excellent even if no treatment is provided and only periodic observation maintained[dovemed.com]
  • Prognosis The naevus remains indefinitely. [ 2 ] Becker naevus syndrome [ 1, 6, 7 ] This is a Becker's naevus with additional abnormalities of underlying tissues derived from ectoderm. It is a type of epidermal naevus syndrome.[patient.info]
  • Prognosis Prognosis is determined mainly by cardiac complications. Most patients with LEOPARD syndrome lead a normal life.[emedicine.medscape.com]

Etiology

  • Etiology The etiology of Becker’s nevus remains unclear. It is a hamartoma of ectodermal and mesodermal derivatives that is thought to be hormonally responsive given the augmented smooth muscle and peripubertal growth.[dermatologyadvisor.com]
  • The exact etiology is unknown, but androgen stimulation may be responsible for the hypertrichosis and darker pigmentation in postpubertal males [5] .[ijsronline.net]
  • The male predominance, onset at or after puberty and the hypertricosis suggest that local androgen hypersensitivity may be an etiological factor.[drsandeshgupta.com]
  • Pathophysiology The pathogenesis and etiology of Becker nevus remain uncertain.[emedicine.com]

Epidemiology

  • In addition, a significant increase in the number of androgen receptors in Becker melanosis lesional skin has been reported. [2] Epidemiology Frequency A study of 19,302 men aged 17-26 years revealed a prevalence of Becker melanosis of 0.52%.[emedicine.com]
  • Epidemiology It is more common in men. One study reported a prevalence of 0.52% in men aged 17-26 years. [ 4 ] Presentation [ 1, 2 ] A large brown area, sometimes covering half the upper back or chest. Most lesions become hairy (hypertrichosis).[patient.info]
  • (Reviews the epidemiology of Becker’s nevus and associated abnormalities.) Chima, KN, Janniger, CK, Schwartz, RA. “Becker’s melanosis”. Cutis. vol. 57. 1996. pp. 311-4. (Comprehensive review article of Becker’s nevus.) Becker, SW.[dermatologyadvisor.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology The pathogenesis and etiology of Becker nevus remain uncertain.[emedicine.com]
  • Pathophysiology Thedevelopmental anomalies associated with Becker’s nevus syndrome,including breast hypoplasia, supernumerary nipples and musculoskeletalanomalies, are similar to the spectrum seen in the epidermal nevussyndrome and suggest mosaicism.[dermatologyadvisor.com]

Prevention

  • Current medical research has not established a way of preventing the occurrence of Becker’s Nevus However, if the signs and symptoms of melanoma (such as a suspicious-looking pigmented spot that changes in color and shape) are observed, then immediate[dovemed.com]
  • Author Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, Rutgers New Jersey Medical School; Visiting Professor, Rutgers University School of Public[emedicine.medscape.com]

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