Benign familial infantile epilepsy is a clinical syndrome that may be more common than is presently recognized. [ncbi.nlm.nih.gov]

Benign (nonfamilial) infantile epilepsy presents in neurologically normal infants in the first year of life. [neupsykey.com]

In this chapter, we describe the wide clinical spectrum associated with PRRT2 mutations and present the current hypotheses on the underlying pathophysiology. [moh-it.pure.elsevier.com]

Patients present with motor arrest, unresponsiveness, head and/or eye deviation to one side, staring, fluttering of eyelids, grunting, cyanosis, diffuse hypertonia and unilateral or bilateral clonic jerks of the limbs. [orpha.net]

EEG is required to distinguish myoclonic seizures from nonictal causes of myoclonus, which can arise from lesions of the cortex, brainstem, spinal cord, or even peripheral nerve (see Workup). [emedicine.medscape.com]

Shorter duration between the onset of IS and initiation of standard treatment appears to lead to an improved outcome; therefore early recognition of the seizures and early treatment are essential. [childneurologyfoundation.org]

Tonic or atonic seizures First-line treatment: offer sodium valproate as first-line treatment. Adjunctive treatment: offer lamotrigine as adjunctive treatment if first-line treatment with sodium valproate is ineffective or not tolerated. [patient.info]

Treatment with anticonvulsant drugs is not necessary but they are often prescribed and are effective at controlling the seizures. This form of epilepsy resolves after one or two years, and appears to be completely benign. [en.wikipedia.org]

Direct in style but comprehensive in content, with ample tables and summaries, the Handbook of Epilepsy Treatment covers: Treatment of the different forms and causes of epilepsy Treatment in the different commonly encountered clinical situations Treatment [books.google.de]

E for further details of pharmacological treatment. [nice.org.uk]

The subjects, from 11 families, were between the ages of 3 and 19 months and had normal neurodevelopmental status, a normal interictal electroencephalogram, a family history of similar seizures, and an excellent prognosis. [ncbi.nlm.nih.gov]

Prognosis The prognosis for children with IS is largely dependent on the underlying cause. The intellectual prognosis for children with IS is generally poor because many babies with IS have neurological impairment prior to the onset of spasms. [childneurologyfoundation.org]

Prognosis The prognosis depends heavily on the underlying etiology and the epilepsy syndrome. Patients with a benign syndrome typically respond well to medication and may outgrow their epilepsy. [emedicine.medscape.com]

Herein, the involvement of the SCN1B gene in the etiology of BFIE, contributing to the disease phenotype as a modifier or part of an oligogenic predisposition, is shown for the first time. Copyright 2017 European Paediatric Neurology Society. [ncbi.nlm.nih.gov]

These seizures are likely also linked in some way to ion channel dysfunction as is found in the familial seizures, but they may be caused by multiple etiologies or occur as a multigenomic entity. [37, 38, 39] These sorts of multifactorial etiologies are [emedicine.medscape.com]

According to ILAE 2010 Etiology Type of Seizures Gender Vaccination Age at Vaccination (mon) Children with vaccination-related seizure onset Genetic Sotos syndrome Multiple simple FS Male MMR 15.5 Genetic Down syndrome Atypical seizure Male dh1 3.0 Genetic [pediatrics.aappublications.org]

[…] of Epilepsy Chapter 6: Epileptogenic Cerebral Cortical Malformations Chapter 7: Exploring the Epilepsiome I: Genetics of Age-Dependent Epileptic Encephalopathies Chapter 8: Exploring the Epilepsiome II: Approaching the Complex Epilepsies SECTION II: Epidemiology [connect.springerpub.com]

Particular updates include full coverage of new developments in epidemiology, genetics, classification, imaging, drug therapy and other treatments. [books.google.ro]

The first section of the book introduces the clinical aspects of the science of epileptology with chapters on pathophysiology, genetics, classification, syndromes, epidemiology, etiology, and differential diagnosis. [books.google.de]

Summary Epidemiology Although BFIE cases have been reported worldwide, prevalence and incidence remain unknown. In an Argentinian case series, BFIE have been listed as the third most common type of epilepsy in the first two years of life. [orpha.net]

In this chapter, we describe the wide clinical spectrum associated with PRRT2 mutations and present the current hypotheses on the underlying pathophysiology. [moh-it.pure.elsevier.com]

The first section of the book introduces the clinical aspects of the science of epileptology with chapters on pathophysiology, genetics, classification, syndromes, epidemiology, etiology, and differential diagnosis. [books.google.de]

As a result, chloride is efficiently pumped from the intracellular milieu, GABA begins to exert its conventional inhibitory action, and the primitive pattern is replaced by more diverse and elaborate patterns of activity. [34] The pathophysiology of benign [emedicine.medscape.com]

Add to Favorites Permissions Contents Untitled Contributors Preface SECTION I: Basic Mechanisms Chapter 1: Pathophysiology of Seizures in the Developing Brain Chapter 2: Ion Channels, Membranes, and Molecules in Epilepsy and Neuronal Excitability Chapter [connect.springerpub.com]

Genetic causes are not directly preventable. Causes are more often preventable as the infant or young child grows older. [childneurologyfoundation.org]

While this condition can be easily controlled by medication, it impacts on quality of life and may prevent people from participating in some activities. [news-medical.net]

Prevention There is no known way to prevent the onset of seizure disorders, but seizures may be controlled and sometimes prevented by the use of medication. [healthofchildren.com]

In addition, parents should also be aware that these drugs may prevent recurrences but do not alter the long-term prognosis for attaining seizure remission. [aafp.org]