Presentation
Modern Surgical Pathology, 2nd Edition presents today's most complete, current, and practical assistance in evaluating and signing out surgical specimens. [books.google.com]
Abstract A case of inverted papilloma of the ureter in a 62-year-old man is presented along with a literature review of 14 cases. [link.springer.com]
In the present case, the patient’s current smoking status was an identifiable risk factor. [academic.oup.com]
variable Present, frequent Present, frequent Present, frequent Low p27 kip1, high MIB1proliferation index Florid von Brunn nests Present, variable Absent Absent Absent Variable Nephrogenicmetaplasia Present Absent Present, frequent Present,rare Variable [abdominalkey.com]
Patients present with dysuria or gross or microscopic hematuria. It has no age predilection. [med-ed.virginia.edu]
Immune System
-
Splenomegaly
This distinguishes Myelofibrosis from Hair Cell Leukemia, which shows splenomegaly, dry tap, and leukopenia. Massive Splenomegaly: The biggest spleens you'll ever see. [kumc.edu]
Hematological
-
Hemophilia A
Epistaxis, lacrimal gland tumors, vicarious menstruation, bleeding disorders such as hemophilia, trauma, orbital varix, canaliculitis and tumors of the lacrimal sac, and frequently, the malignant tumors have been reported as the causes of bloody tears [eyewiki.aao.org]
EPIDEMIOLOGY: Rarer than Hemophilia-A SYMPTOMS: Identical to Hemophilia-A LABS: Prolonged Partial Thromboplastin Time (PTT), indicating a defect in the Intrinsic Pathway. [kumc.edu]
Entire Body System
-
Pathologist
Edited by four leading surgical pathologists - Noel Weidner, MD, Richard J. Cote, MD, Saul Suster, MD and Lawrence M. [books.google.com]
The pathologists work together in a team, and there are often multiple pathologists assessing the tissue sample before the final diagnosis is made. [oncolex.org]
Transitional epithelium / urothelium The International Society of Urologic Pathologists began promoting the term urothelium as preferred terminology about 1998, but the current nomenclature has not been adopted by all pathologists and causes confusion [training.seer.cancer.gov]
-
Hodgkin Lymphoma
Lymphoma and Non Hodgkins Lymphoma Ophthalmic Primary Sites Introduction and Orientation Eyelid Adnexa Conjunctiva Uvea Malignant Melanoma Retina Orbit Sarcomas Lymphomas and Lacrimal Gland Carcinomas Online Chapters Appendix ARecommended Reading and [books.google.com]
Non-Hodgkin’s lymphoma of the renal pelvis. Clin Lymphoma Myeloma 2006 ; 6 ( 5 ): 404–6. [cambridge.org]
Involvement Uncommon Common (30% of cases) HODGKIN'S LYMPHOMA : EPIDEMIOLOGY: Relatively rare disease. [kumc.edu]
-
Splenectomy
TREATMENT: Disease usually responds to steroids; if that fails, do splenectomy. THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP): Simultaneous thrombosis, blood clotting, and bleeding ------ end-organ infarcts. [kumc.edu]
Skin
-
Pruritus
SYMPTOMS: Pruritus, bleeding, ulcer, and a mass. Prognosis is good: 90% survival with no metastasis. Metastasis goes to inguinal or femoral nodes. VERRUCOUS CARCINOMA (GIANT CONDYLOMA) : PATHOGENESIS: HPV 6 CLINICAL: Good prognosis. [kumc.edu]
Eyes
-
Lacrimation
SystemMelanoma Musculoskeletal Soft Tissue Sarcoma Osseous Skeletal System Hodgkins Lymphoma and Non Hodgkins Lymphoma Ophthalmic Primary Sites Introduction and Orientation Eyelid Adnexa Conjunctiva Uvea Malignant Melanoma Retina Orbit Sarcomas Lymphomas and Lacrimal [books.google.com]
A variety of tumors can arise in the canaliculus, lacrimal sac, and tha nasolacrimal duct, with the mayority originating in the lacrimal sac. [1] Lacrimal sac tumors are usually primary and of epithelial origin. [eyewiki.aao.org]
Urogenital
-
Hematuria
Patients present with dysuria or gross or microscopic hematuria. It has no age predilection. [med-ed.virginia.edu]
In this case, in addition to gross hematuria, the patient presented with obstructive voiding symptoms likely secondary to the location of the IPB. [academic.oup.com]
The hematuria is caused by a small renal cell carcinoma in the left kidney Pitfalls: Large bloodclot in the bladder that could be mistaken for a tumor in a patient with dissiminated prostate cancer invading the bladder [ultrasoundcases.info]
Figure 12a Figure 12b UCC in a 78-year-old woman with hematuria. [pubs.rsna.org]
CASE REPORT Male patient, 55 years, with a clinical picture of macroscopic hematuria and insidious lower back pain similar to cramps for about six months, which became stronger in recent months. The patient reports a fever, not measured. [scielo.br]
Workup
Progress logically from the histologic pattern, through the appropriate workup, around the pitfalls, to the best diagnosis. [books.google.ro]
C 18 Complete blood count, blood chemistry tests, liver function tests, chest radiography, and CT or magnetic resonance imaging of the abdomen and pelvis should be included in the metastatic workup for invasive bladder cancer. [aafp.org]
Investigation and Diagnosis Cystoscopy The primary modality for the diagnosis of bladder carcinoma Permits biopsy and resection of papillary tumors Upper urinary tract imaging Necessary for the hematuria workup American Urologic Association Best [slideshare.net]
Figure 20b Conclusion CT urography has become widely accepted as the new first-line imaging modality in the workup of hematuria in adult patients and in the initial staging and surveillance of UCC. [pubs.rsna.org]
Treatment
The primary treatment for choroid plexus tumors is surgery to remove them. At UPMC, the preferred surgical treatment for choroid plexus tumors is Neuroendoport surgery. [upmc.com]
Treatment options under clinical evaluation: The development of new instrumentation for endourological treatment of upper tract transitional cell cancer has provided new options for regional management of these cancers. [cancer.gov]
Trials are often designed to treat a certain stage of cancer, either as the first form of treatment offered, or as an option for treatment after other treatments have failed to work. [oncolink.org]
From the standpoint of clinicopathological features, inverted papillary tumor of the ureter should be distinguished from its exophytic counterpart with respect to the treatment. [ncbi.nlm.nih.gov]
Results The clinical features and treatment approaches of each patient are summarized in Table I. [spandidos-publications.com]
Prognosis
Prognosis Non–muscle invasive bladder cancer has a good prognosis, with 5-year survival rates of 82-100%. [slideshare.net]
POOR PROGNOSIS: Two abnormalities associated with poorer prognosis. Aneuploidy of chromosomes 7 and 8 is associated with poor prognosis. Chromosome 16 has Cadherin and Catenin proteins, which are associated with poor prognosis when present. [kumc.edu]
Patients with metastatic disease, in contrast, have a poor prognosis (5-year survival of 6%) 4. [radiopaedia.org]
Clinical Pathology of Urological Tumours is presented as a highly attractive, coherently structured, full colour atlas, featuring sections on: Renal Tumours Adrenal Glands Pathology of tumours of the urinary bladder Prostate cancer origins, diagnosis and prognosis [books.google.ro]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
Cancer of bladder 1) Incidence and prevalence. 2) Etiology/ Risk factors. 3) Pathology. 4) Clinical features. 5) Investigation and diagnosis. 6) Staging and Management. 7) Prognosis 18. [slideshare.net]
[…] exophytic neoplasm composed of a delicate fibrovascular core covered by normal-appearing urothelium (1,2). a low incidence – representing 1-4% of bladder tumours. cigarette smoking and occupational exposure to aromatic amines are the most important etiology [wsoonli15.wordpress.com]
Human papillomavirus is not an etiologic agent of urothelial inverted papillomas. Am J Surg Pathol. 2013 Aug. 37(8):1223-8. [Medline]. van Oers JM, Lurkin I, van Exsel AJ, et al. [emedicine.medscape.com]
Fibroepithelial polyps have a variety of proposed etiologies including: congenital development, infectious, inflammatory, or secondary to an obstructive process. The pathology report revealed right fibroepithelial polyps. [medical-dictionary.thefreedictionary.com]
Epidemiology
Epidemiology The risk factors for squamous papilloma are similar to those for other urothelial neoplasms; cigarette smoking and occupational exposure to aromatic amines are among the most important. [emedicine.medscape.com]
EPIDEMIOLOGY: 75% of men have it by age 80. Some people say even higher. Especially common in African American men. [kumc.edu]
Definition / general Discrete papillary growth with a central fibrovascular core lined by urothelium of normal thickness and cytology Epidemiology Uncommon if use restrictive diagnostic criteria (less than 1% of bladder tumors) Tends to occur in younger [pathologyoutlines.com]
Pathophysiology
However, the occurrence of upper urinary tract localization is not surprising when considering how the urothelial-lined tissue behaves as a single pathophysiological unit. [spandidos-publications.com]
Prevention
It is unclear whether condoms can prevent the transmission of HPV (though condoms can prevent the transmission of most other sexually transmitted diseases ). [britannica.com]
Since prevention is generally not possible, it is important to be aware of the risk factors of breast lumps. [dovemed.com]
Read more about the causes of bladder cancer and preventing bladder cancer. Treating bladder cancer In cases of non-muscle-invasive bladder cancer, it's usually possible to remove the cancerous cells while leaving the rest of the bladder intact. [nhs.uk]
How can I prevent bladder cancer? Smoking cessation is the best way to prevent bladder cancer. Additionally, reducing the exposure to cancer causing agents should decrease the risk of developing bladder cancer. [oncolink.org]