If surgery seems likely (and bearing in mind the age of most men who present with this condition) further questions to assess fitness for surgery may be in order. Urinary frequency is often a presenting symptom. [patient.info]

This study reports for the first time that post-coital gross hematuria is one of the clinical presentations of BPH, which can be successfully treated with 5alpha-reductase inhibitor. [ncbi.nlm.nih.gov]

He has presented at over seventeen conferences and acts as a reviewer for 13 journals. He has been the editor of The Journal of Urology and Research since June 2014. [elsevier.com]

Presentation An 80 year-old-man presented with urinary retention and hematuria. The PSA blood level was 8 ng/ml. Caption: Suprapubic ultrasound Description: Suprapubic ultrasound demonstrates an enlarged prostate. [sonoworld.com]

• Inflammation

  Inflammation Most observational studies suggest that inflammation is intimately linked to the development of BPH and LUTS. The mechanisms underpinning this relationship are unclear. [doi.org]

  Continued Inflammation Key? Doctors don't know exactly how BPH develops, but inflammation may be part of the process. Anti-inflammatory drugs, such as ibuprofen and naproxen, are often used to treat arthritis inflammation. [webmd.com]

  Age-related changes associated with metabolic disturbances, changes in hormone balance, and chronic inflammation may cause BPH development. [ncbi.nlm.nih.gov]

• Recurrent Urinary Tract Infection

  Chronic urologic conditions, including benign prostatic hyperplasia, recurrent urinary tract infections, and urinary incontinence, are common in older adults. [ncbi.nlm.nih.gov]

  Surgery should be reserved for patients who either have failed medical management or have complications from BPH, such as recurrent urinary tract infections, refractory urinary retention, bladder stones, or renal insufficiency as a result of obstructive [doi.org]

• Fishing

  Materials and methods: Our objective was to evaluate the association between HER-2/neu, c-myc, p53, and clinicopathological variables in 45 patients diagnosed with benign prostatic hyperplasia using fluorescence in situ hybridization (FISH). [ncbi.nlm.nih.gov]

  Upper urinary tract abnormalities that usually result from bladder outlet obstruction include upward displacement of the terminal portions of the ureters (fish hooking), ureteral dilation, and hydronephrosis. [merckmanuals.com]

  Other cold-water fish, such as sardines and trout, are also rich in these types of fats. Tomatoes: Tomatoes are packed with lycopene, an antioxidant that may benefit prostate gland cells. [medicalnewstoday.com]

• Chronic Infection

  II: Its adjunctive role in chronic urinary infection J Urol 1965 94 : 300–303 47 Stover SL, Fleming WC. [doi.org]

• Failure to Thrive

  In the absence of family history of X-SCID and prior to newborn screening for X-SCID, most males with typical X-SCID come to medical attention between ages three and six months with failure to thrive, oral/diaper candidiasis, absent tonsils and lymph [ncbi.nlm.nih.gov]

  Frailty and failure to thrive. In: Hazzard WR, editor;, Blass JP, editor;, Ettinger WH Jr, editor;, Halter JB, editor;, Ouslander J, editor., eds. Principles of Geriatric Medicine and Gerontology. New York: McGraw-Hill. Pp.1487–1502. [web.archive.org]

• Alopecia

  The prevalence of alopecia, another potential indication for 5-alpha reductase inhibitor use, was 0.1%. [ajmc.com]

  14,15 This may have implications on medication adherence and persistence of adverse effects, which may last well after the discontinuation of the drug. 13 Another difference is that finasteride is indicated for male pattern hair loss (androgenetic alopecia [uspharmacist.com]

• Hirsutism

  […] glomerulonephritis糸球体腎炎 glomerulus (pl. glomeruli)糸球体 glycosuria (glucosuria)糖尿 gonorrhea淋病 gout痛風 gross (macro) hematuria肉眼的血尿 h hematogenous血液原の、血行性の hematuria血尿 hemodialysis　（HD）血液透析 Henle's loop　（loop of Henle）ヘンレループ hermaphroditism半陰陽 herpes単純疱疹 hirsutism [tokyo-med.ac.jp]

• Aggressive Behavior

  Most of these tumors follow a benign course, with only a small percentage showing aggressive behavior, perhaps due to early stage at diagnosis. [emedicine.medscape.com]

  High GATA-4 expression associates with aggressive behavior, whereas low anti-Mullerian hormone expression associates with growth potential of ovarian granulosa cell tumors. J Clin Endocrinol Metab. 2005;90:6529–6535. doi: 10.1210/jc.2005-0921. [ncbi.nlm.nih.gov]

• Asthenia

  The most common adverse effects associated with SR, finasteride, and tamsulosin were asthenia (abnormal loss of strength), decreased libido, diarrhea, dizziness, ejaculation disorders, gastrointestinal distress, headaches, and postural hypotension. no [doi.org]

  Table 3 Summary table of adverse effects (SR vs tamsulosin) * SR § TAM Comparisons P = 0.05 n/N (%) Asthenia 10/349 (3) (1 trial) 10/354 (3) (1 trial) P = NS Decrease in libido 13/890 (1) (2 trials) 4/354 (1) (1 trial) P = NS Dizziness 10/349 (3) (1 trial [ncbi.nlm.nih.gov]

• Sleep Disturbance

  disturbances, and they often already suffer from dry mouth, dry eye, and vision problems as well as GI motility problems including constipation. 30 Kay et al studied the differential effects oxybutynin ER versus the drug darifenacin on memory in older [ncbi.nlm.nih.gov]

  Several noncontrolled studies of hypogonadal men found some evidence of increases in disordered breathing events during testosterone therapy but with wide variability in the extent of sleep disturbances between individuals ( Appendix C ). [web.archive.org]

• Urinary Retention

  Incidence of Urinary retention: The incidence of urinary retention is 4.5–18/1000 man-years. Symptoms (LUTS), prostate size and a low maximum flow rate are risk factors for urinary retention. [urology-textbook.com]

  The complications of benign prostatic hyperplasia may include acute urinary retention chronic, or long lasting, urinary retention blood in the urine urinary tract infections (UTIs) bladder damage kidney damage bladder stones Most men with benign prostatic [niddk.nih.gov]

  Some patients present with sudden, complete urinary retention, with marked abdominal discomfort and bladder distention. [merckmanuals.com]

  COMPLICATIONS Recurring urinary retention is a common complication of BPH. Men at greater risk for urinary retention are those with PSA levels above 1.6 ng/mL or prostate volumes over 31 mL. [journals.lww.com]

  We herein report a 17-year-old boy who presented with acute urinary retention due to BPH and was treated with endoscopic transurethral resection of the prostate (TUR-P). [ncbi.nlm.nih.gov]

• Enlargement of the Prostate

  Enlarged prostate (BPH) definition and facts The prostate gland produces a fluid that becomes part of the semen. Benign prostatic hyperplasia, or BPH, involves enlargement of the prostate gland. [medicinenet.com]

  […] benign enlargement of the prostate benign prostate enlargement BPH BEP BPE prostatic hyperplasia Benign Hyperplasia of Prostate Benign Hyperplasia of the Prostate Benign Prostatic Hypertrophy Benign Prostate Hyperplasia PROSTATIC HYPERPLASIA, BENIGN [wikidata.org]

  Description What is benign prostatic hyperplasia (enlarged prostate)? Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement of the prostate, the gland that transports sperm during ejaculation. [bostonscientific.com]

  By age 60, half of all men have an enlarged prostate. By age 80, about 80 percent of all men have an enlarged prostate. The prostate forms part of the male reproductive system and helps produce semen. It is located at the base of the male bladder. [uwhealth.org]

• Nocturia

  Fluid diary A fluid diary is useful for patients complaining of frequency or nocturia and can help quantify the volume of fluid intake, frequency of urination, and volumes voided. [mdedge.com]

  Theabnormalities included subacute hemorrhagein… Desmopressin Effectively Treats Nocturia in BPH Nocturia improved 43% in patients receiving oral desmopressin alone and 64.3% in those receiving desmopressin and an alpha-blocker. [renalandurologynews.com]

  This indicates that Pygeum africanum resulted in a statistically significant moderate to large improvement in nocturia. [doi.org]

  The possibility that the monthly period of nocturia is a general phenomenon and is coupled to a monthly menstrual period, and the implications for more accurate diagnosis and new modes of therapy, are discussed. [ncbi.nlm.nih.gov]

• Urinary Incontinence

  Chronic urologic conditions, including benign prostatic hyperplasia, recurrent urinary tract infections, and urinary incontinence, are common in older adults. [ncbi.nlm.nih.gov]

  […] or without urgency urinary incontinence). [doi.org]

  Most Transient SUI After HoLEP Resolves Within 6 Weeks Of patients who had transient stress urinary incontinence after holmium laser enucleation of the prostate, 88.6% experienced resolution of the incontinence within 6 weeks after the procedure. [renalandurologynews.com]

  Overactive bladder is a condition in which the bladder muscles contract uncontrollably and cause urinary frequency, urinary urgency, and urinary incontinence. Antimuscarinics are a class of medications that relax the bladder muscles. [niddk.nih.gov]

• Prostatic Disease

  An increase in immunoreactive CK-BB or CK-BB activity in patients with prostatic disease has been proposed as an indication of prostatic adenocarcinoma. [ncbi.nlm.nih.gov]

  Uroselectivity Revisited Subject Categories Medicine, Dentistry, Nursing & Allied Health Medicine Urology Prostatic Disease BISAC Subject Codes/Headings: MED088000 MEDICAL / Urology [routledge.com]

  Saw palmetto for benign prostatic hyperplasia. The New England journal of medicine. Feb 9 2006;354(6):557-566. Shinohara K. Thermal ablation of prostate diseases: advantages and limitations. [urology.ucsf.edu]

Primary care physicians are uniquely positioned to screen for BPH, conduct a timely diagnostic workup, and if indicated, initiate medical therapy. [mdedge.com]

EEG is required to distinguish myoclonic seizures from nonictal causes of myoclonus, which can arise from lesions of the cortex, brainstem, spinal cord, or even peripheral nerve (see Workup). [emedicine.medscape.com]

In addition, peak urinary flow, voided volume, and symptoms may worsen over time in men with untreated BPH (see Workup ). The risk of AUR and the need for corrective surgery increases with age. [emedicine.com]

• Nephrolithiasis

  […] treatment option in patients who are unresponsive to medical treatment in patients with recurrent UTIs, bladder stones, or gross hematuria secondary to their BPH complication retrograde ejaculation erectile dysfunction this is uncommon Complications UTI Nephrolithiasis [medbullets.com]

  […] presence of other positive diagnostic outcomes, an elevated PSA level can help a primary care provider arrive at a BPH diagnosis. 1 Urinalysis Ordering a urinalysis is recommended as a primary step in order to exclude UTI, prostatitis, cystolithiasis, nephrolithiasis [journals.lww.com]

  Krambeck, Walter Astorne, Erik Bergstralh and John Lieske, Sex Steroid Hormone Levels May Not Explain Gender Differences in Development of Nephrolithiasis, Journal of Endourology, 29, 12, (1341), (2015). [doi.org]

  メサンギウム細胞 metastatic carcinoma転移性癌 microscopic hematuria顕微鏡的血尿 micturition hyperreflexia 排尿反射亢進 micturition reflex 排尿反射 minimally invasive therapy低侵襲治療 mycobacteriaミコバクテリア、マイコバクテリア n needle biopsy針生検 neobladder 新膀胱 nephrectomy腎摘出［術］、腎摘、腎切除［術］ nephritis腎炎 nephrolithiasis [tokyo-med.ac.jp]

• Testosterone Increased

  PSA levels increased significantly in the testosterone-treated group by six months and then leveled off. No significant increase was seen in the placebo group. [web.archive.org]

• Bladder Trabeculation

  The false passage will disappear also on cystoscopy and IC can be safely restarted. 77 Other complications such as hydronephrosis, vesico-ureteral reflux, and bladder cancer seem to relate rather to infection, bladder trabeculation, detrusor pressure [doi.org]

Alternative Treatments Alternative treatments include nutritional supplements, herbal remedies, and hydrotherapy. [healthcentral.com]

The 1470-nm laser vaporization treatment protected patients against BPH, indicating that 1470-nm laser vaporization might be important on treating BPH, which provided solid foundation for further clinical treatment. [ncbi.nlm.nih.gov]

[…] complications. 9 Treatment decisions are based on the severity of the condition. [journals.lww.com]

Mayo Clinic urologists are actively investigating drugs and treatments, developing novel therapies and conducting ongoing research into new treatments and minimally invasive procedures. [mayo.edu]

In June 2016, National Institute of Health and Care Excellence (NICE) approved GreenLight XPS laser treatment for the treatment of BPH. [globenewswire.com]

(Outcomes/Resolutions) The prognosis of Benign Prostatic Hyperplasia varies from individual to individual. [dovemed.com]

Conclusion: In this study, we discussed important genetic markers in benign prostatic hyperplasia patients which may, in the future, be used as markers for diagnosis and prognosis, as well as targets for therapeutic intervention. [ncbi.nlm.nih.gov]

Can prostatitis and BPH be cured (prognosis)? The prognosis for BPH for most patients that undergo treatment is good to fair, depending upon how well patients respond. [medicinenet.com]

Prognosis The prognosis depends heavily on the underlying etiology and the epilepsy syndrome. Patients with a benign syndrome typically respond well to medication and may outgrow their epilepsy. [emedicine.medscape.com]

Owing to the limited number of cases, the etiology and management of BPH in the first two decades is not clear. [ncbi.nlm.nih.gov]

You are here: Urology Textbook > Prostate > BPH > Definition, epidemiology, etiology Benign prostatic hyperplasia (1/6): definitions, epidemiology and etiology Benign prostatic hyperplasia (2/6): signs and symptoms Benign prostatic hyperplasia (3/6): [urology-textbook.com]

Epidemiologic Risk Factors for Benign Prostatic Hyperplasia (BPH): The epidemiology of BPH is fairly constant, some genetic factors or environmental influences may modestly increase the risk for BPH. [urology-textbook.com]

The term LUTS describes a distinct phenotype and allows for a broad epidemiologic description of urinary symptoms at a population level. [ncbi.nlm.nih.gov]

Keywords Benign prostatic hyperplasia Lower urinary tract symptoms American Urological Association Symptom Index BPH LUTS Epidemiology Risk factor Exercise Physical activity Metabolic syndrome Modifiable Obesity Diabetes Introduction The epidemiology [doi.org]

Published on Jul 20, 2012 Pathophysiology lecture on the physiology of the prostate gland, and the etiology of benign prostatic hyperplasia (BPH). Distinction made between benign prostatic hypertrophy and hyperplasia. [youtube.com]

In this study, we propose a novel and tested pathophysiological mechanism for the evolution of BPH and suggest a tested and effective treatment. [ncbi.nlm.nih.gov]

How can benign prostatic hyperplasia be prevented? Researchers have not found a way to prevent benign prostatic hyperplasia. [niddk.nih.gov]

Currently, there are no guidelines or methods available for the prevention of Benign Prostatic Hyperplasia. [dovemed.com]

The 5-α reductase inhibitors (finasteride and dutasteride) decrease serum concentrations of DHT [ 24 ] and prevent progression of clinical BPH [ 25 ]. However, it is not known whether finasteride or dutasteride will prevent incident BPH. [doi.org]

Research is ongoing to identify who might benefit from early treatment to prevent BPH. According to the American Cancer Society, most cases of prostate cancer can't be prevented. This is because prostate cancer's causes are still unknown. [webmd.com]