Presentation
If surgery seems likely (and bearing in mind the age of most men who present with this condition) further questions to assess fitness for surgery may be in order. Urinary frequency is often a presenting symptom. [patient.info]
This study reports for the first time that post-coital gross hematuria is one of the clinical presentations of BPH, which can be successfully treated with 5alpha-reductase inhibitor. [ncbi.nlm.nih.gov]
He has presented at over seventeen conferences and acts as a reviewer for 13 journals. He has been the editor of The Journal of Urology and Research since June 2014. [elsevier.com]
Presentation An 80 year-old-man presented with urinary retention and hematuria. The PSA blood level was 8 ng/ml. Caption: Suprapubic ultrasound Description: Suprapubic ultrasound demonstrates an enlarged prostate. [sonoworld.com]
Entire Body System
- Recurrent Urinary Tract Infection
Chronic urologic conditions, including benign prostatic hyperplasia, recurrent urinary tract infections, and urinary incontinence, are common in older adults. [ncbi.nlm.nih.gov]
Surgery should be reserved for patients who either have failed medical management or have complications from BPH, such as recurrent urinary tract infections, refractory urinary retention, bladder stones, or renal insufficiency as a result of obstructive [doi.org]
- Inguinal Hernia
Straining also may acutely cause vasovagal syncope and, over the long term, may cause dilation of hemorrhoidal veins or inguinal hernias. [merckmanuals.com]
Neurologic
- Seizure
Practically speaking, myoclonic seizures can be grouped into the following categories (myoclonic absences, myoclonic tonic seizures, and myoclonic clonic seizure types are not discussed here): Early infantile epileptic encephalopathies [2] - This includes [emedicine.medscape.com]
Ictal EEG shows that partial seizures originate from the parietal-occipital region and that the side of the hemisphere involved can vary between episodes. Seizures can sometimes spread and involve the entire brain. [orpha.net]
Orpha Number: 140927 Definition Benign familial neonatal-infantile seizures (BFNIS) is a benign familial epilepsy syndrome with an intermediate phenotype between benign familial neonatal seizures (BFNS) and benign familial infantile seizures (BFIS; see [rarediseases.info.nih.gov]
] Seizures, Benign Familial Infantile, 3 [T804677] Convulsions, Benign Familial Infantile, 1 [T834090] Seizures, Benign Familial Infantile, 1 [T834093] Benign Familial Infantile Convulsions Syndrome [T834250] Benign Infantile Familial Convulsions [T834251 [medvik.cz]
The average onset age of the epilepsy was 6.8 years (SD=2.1) and the average seizure number was 4.2 (SD=2.9). The mean time since the last seizure was 15.7 months (SD=17.7). [scielo.br]
- Asthenia
The most common adverse effects associated with SR, finasteride, and tamsulosin were asthenia (abnormal loss of strength), decreased libido, diarrhea, dizziness, ejaculation disorders, gastrointestinal distress, headaches, and postural hypotension. no [doi.org]
Table 3 Summary table of adverse effects (SR vs tamsulosin) * SR § TAM Comparisons P = 0.05 n/N (%) Asthenia 10/349 (3) (1 trial) 10/354 (3) (1 trial) P = NS Decrease in libido 13/890 (1) (2 trials) 4/354 (1) (1 trial) P = NS Dizziness 10/349 (3) (1 trial [ncbi.nlm.nih.gov]
- Sleep Disturbance
disturbances, and they often already suffer from dry mouth, dry eye, and vision problems as well as GI motility problems including constipation. 30 Kay et al studied the differential effects oxybutynin ER versus the drug darifenacin on memory in older [ncbi.nlm.nih.gov]
Several noncontrolled studies of hypogonadal men found some evidence of increases in disordered breathing events during testosterone therapy but with wide variability in the extent of sleep disturbances between individuals ( Appendix C ). [web.archive.org]
Urogenital
- Urinary Retention
Incidence of Urinary retention: The incidence of urinary retention is 4.5–18/1000 man-years. Symptoms (LUTS), prostate size and a low maximum flow rate are risk factors for urinary retention. [urology-textbook.com]
The complications of benign prostatic hyperplasia may include acute urinary retention chronic, or long lasting, urinary retention blood in the urine urinary tract infections (UTIs) bladder damage kidney damage bladder stones Most men with benign prostatic [niddk.nih.gov]
Some patients present with sudden, complete urinary retention, with marked abdominal discomfort and bladder distention. [merckmanuals.com]
COMPLICATIONS Recurring urinary retention is a common complication of BPH. Men at greater risk for urinary retention are those with PSA levels above 1.6 ng/mL or prostate volumes over 31 mL. [journals.lww.com]
We herein report a 17-year-old boy who presented with acute urinary retention due to BPH and was treated with endoscopic transurethral resection of the prostate (TUR-P). [ncbi.nlm.nih.gov]
- Enlargement of the Prostate
Enlarged prostate (BPH) definition and facts The prostate gland produces a fluid that becomes part of the semen. Benign prostatic hyperplasia, or BPH, involves enlargement of the prostate gland. [medicinenet.com]
[…] benign enlargement of the prostate benign prostate enlargement BPH BEP BPE prostatic hyperplasia Benign Hyperplasia of Prostate Benign Hyperplasia of the Prostate Benign Prostatic Hypertrophy Benign Prostate Hyperplasia PROSTATIC HYPERPLASIA, BENIGN [wikidata.org]
Description What is benign prostatic hyperplasia (enlarged prostate)? Benign prostatic hyperplasia (BPH) is a non-cancerous enlargement of the prostate, the gland that transports sperm during ejaculation. [bostonscientific.com]
By age 60, half of all men have an enlarged prostate. By age 80, about 80 percent of all men have an enlarged prostate. The prostate forms part of the male reproductive system and helps produce semen. It is located at the base of the male bladder. [uwhealth.org]
- Nocturia
Fluid diary A fluid diary is useful for patients complaining of frequency or nocturia and can help quantify the volume of fluid intake, frequency of urination, and volumes voided. [mdedge.com]
Theabnormalities included subacute hemorrhagein… Desmopressin Effectively Treats Nocturia in BPH Nocturia improved 43% in patients receiving oral desmopressin alone and 64.3% in those receiving desmopressin and an alpha-blocker. [renalandurologynews.com]
This indicates that Pygeum africanum resulted in a statistically significant moderate to large improvement in nocturia. [doi.org]
The possibility that the monthly period of nocturia is a general phenomenon and is coupled to a monthly menstrual period, and the implications for more accurate diagnosis and new modes of therapy, are discussed. [ncbi.nlm.nih.gov]
- Urinary Incontinence
Chronic urologic conditions, including benign prostatic hyperplasia, recurrent urinary tract infections, and urinary incontinence, are common in older adults. [ncbi.nlm.nih.gov]
[…] or without urgency urinary incontinence). [doi.org]
Most Transient SUI After HoLEP Resolves Within 6 Weeks Of patients who had transient stress urinary incontinence after holmium laser enucleation of the prostate, 88.6% experienced resolution of the incontinence within 6 weeks after the procedure. [renalandurologynews.com]
Overactive bladder is a condition in which the bladder muscles contract uncontrollably and cause urinary frequency, urinary urgency, and urinary incontinence. Antimuscarinics are a class of medications that relax the bladder muscles. [niddk.nih.gov]
- Prostatic Disease
An increase in immunoreactive CK-BB or CK-BB activity in patients with prostatic disease has been proposed as an indication of prostatic adenocarcinoma. [ncbi.nlm.nih.gov]
Uroselectivity Revisited Subject Categories Medicine, Dentistry, Nursing & Allied Health Medicine Urology Prostatic Disease BISAC Subject Codes/Headings: MED088000 MEDICAL / Urology [routledge.com]
Saw palmetto for benign prostatic hyperplasia. The New England journal of medicine. Feb 9 2006;354(6):557-566. Shinohara K. Thermal ablation of prostate diseases: advantages and limitations. [urology.ucsf.edu]
Workup
Primary care physicians are uniquely positioned to screen for BPH, conduct a timely diagnostic workup, and if indicated, initiate medical therapy. [mdedge.com]
EEG is required to distinguish myoclonic seizures from nonictal causes of myoclonus, which can arise from lesions of the cortex, brainstem, spinal cord, or even peripheral nerve (see Workup). [emedicine.medscape.com]
In addition, peak urinary flow, voided volume, and symptoms may worsen over time in men with untreated BPH (see Workup ). The risk of AUR and the need for corrective surgery increases with age. [emedicine.com]
Serum
- Hyponatremia
However, technical advances such as the use of bipolar resectoscopes, which allow use of saline irrigation, have greatly improved the safety of TURP by averting hemolysis and hyponatremia. [merckmanuals.com]
However, technical advances such as the use of a bipolar resectoscope, which allows use of saline irrigation, have greatly improved the safety of TURP by averting hemolysis and hyponatremia. [msdmanuals.com]
TURP is effective for improving BPH symptoms but may cause complications such as hemorrhage, hyponatremia, and retrograde ejaculation. [journals.lww.com]
Conivaptan is the first medication approved by US Food and Drug Administration for the treatment of euvolemic hyponatremia in those with heart failure.[40] In rare cases hypertonic 3% saline together with diuretics may be used to correct hyponatremia. [en.wikipedia.org]
- Testosterone Increased
PSA levels increased significantly in the testosterone-treated group by six months and then leveled off. No significant increase was seen in the placebo group. [ncbi.nlm.nih.gov]
Cystoscopy
- Bladder Trabeculation
The false passage will disappear also on cystoscopy and IC can be safely restarted. 77 Other complications such as hydronephrosis, vesico-ureteral reflux, and bladder cancer seem to relate rather to infection, bladder trabeculation, detrusor pressure [doi.org]
Treatment
Alternative Treatments Alternative treatments include nutritional supplements, herbal remedies, and hydrotherapy. [healthcentral.com]
The 1470-nm laser vaporization treatment protected patients against BPH, indicating that 1470-nm laser vaporization might be important on treating BPH, which provided solid foundation for further clinical treatment. [ncbi.nlm.nih.gov]
[…] complications. 9 Treatment decisions are based on the severity of the condition. [journals.lww.com]
Mayo Clinic urologists are actively investigating drugs and treatments, developing novel therapies and conducting ongoing research into new treatments and minimally invasive procedures. [mayo.edu]
In June 2016, National Institute of Health and Care Excellence (NICE) approved GreenLight XPS laser treatment for the treatment of BPH. [globenewswire.com]
Prognosis
(Outcomes/Resolutions) The prognosis of Benign Prostatic Hyperplasia varies from individual to individual. [dovemed.com]
Conclusion: In this study, we discussed important genetic markers in benign prostatic hyperplasia patients which may, in the future, be used as markers for diagnosis and prognosis, as well as targets for therapeutic intervention. [ncbi.nlm.nih.gov]
Can prostatitis and BPH be cured (prognosis)? The prognosis for BPH for most patients that undergo treatment is good to fair, depending upon how well patients respond. [medicinenet.com]
Prognosis The prognosis depends heavily on the underlying etiology and the epilepsy syndrome. Patients with a benign syndrome typically respond well to medication and may outgrow their epilepsy. [emedicine.medscape.com]
Etiology
Owing to the limited number of cases, the etiology and management of BPH in the first two decades is not clear. [ncbi.nlm.nih.gov]
You are here: Urology Textbook > Prostate > BPH > Definition, epidemiology, etiology Benign prostatic hyperplasia (1/6): definitions, epidemiology and etiology Benign prostatic hyperplasia (2/6): signs and symptoms Benign prostatic hyperplasia (3/6): [urology-textbook.com]
Epidemiology
Epidemiologic Risk Factors for Benign Prostatic Hyperplasia (BPH): The epidemiology of BPH is fairly constant, some genetic factors or environmental influences may modestly increase the risk for BPH. [urology-textbook.com]
The term LUTS describes a distinct phenotype and allows for a broad epidemiologic description of urinary symptoms at a population level. [ncbi.nlm.nih.gov]
Keywords Benign prostatic hyperplasia Lower urinary tract symptoms American Urological Association Symptom Index BPH LUTS Epidemiology Risk factor Exercise Physical activity Metabolic syndrome Modifiable Obesity Diabetes Introduction The epidemiology [doi.org]
Pathophysiology
Published on Jul 20, 2012 Pathophysiology lecture on the physiology of the prostate gland, and the etiology of benign prostatic hyperplasia (BPH). Distinction made between benign prostatic hypertrophy and hyperplasia. [youtube.com]
In this study, we propose a novel and tested pathophysiological mechanism for the evolution of BPH and suggest a tested and effective treatment. [ncbi.nlm.nih.gov]
Prevention
How can benign prostatic hyperplasia be prevented? Researchers have not found a way to prevent benign prostatic hyperplasia. [niddk.nih.gov]
Currently, there are no guidelines or methods available for the prevention of Benign Prostatic Hyperplasia. [dovemed.com]
The 5-α reductase inhibitors (finasteride and dutasteride) decrease serum concentrations of DHT [ 24 ] and prevent progression of clinical BPH [ 25 ]. However, it is not known whether finasteride or dutasteride will prevent incident BPH. [doi.org]
Research is ongoing to identify who might benefit from early treatment to prevent BPH. According to the American Cancer Society, most cases of prostate cancer can't be prevented. This is because prostate cancer's causes are still unknown. [webmd.com]