The disease usually affects persons in the sixth decade of life and most commonly presents as rectal bleeding, pain, or constipation, while 50% of patients are asymptomatic, with tumors found during routine endoscopy. [emedicine.medscape.com]

[…] necropsy with considerable left ventricular hypertrophy (heart weight 750 g) and then reviewed their medical records to determine whether signs and symptoms of right-sided heart failure were isolated or simply preceded signs of left-sided heart failure (dyspnea [ncbi.nlm.nih.gov]

[…] review of 59 case studies by Veyssier-Belot, C et al. in 1996 reported the following symptoms in order of frequency of occurrence: [6] Bone pain Retroperitoneal fibrosis Diabetes insipidus Exophthalmos Xanthomas Neurological signs ( including ataxia ) Dyspnea [en.wikipedia.org]

During subsequent years he developed evidence of severe heart failure, runs of ventricular tachycardia, atrial fibrillation, and a murmur consistent with mitral regurgitation. An intracardiac defibrillator was inserted when he was 63 years old. [ncbi.nlm.nih.gov]

In 1955, Selzer and colleagues ( 6 ) ( Figure 1 ) described a 62-year-old man with severe hypertension (blood pressure 260/140 mm Hg) hospitalized because of nausea, hepatomegaly, distended neck veins, and clear lung fields. [ncbi.nlm.nih.gov]

Palliation of carcinoid heart disease. Arch Surg. 1987 Sep. 122(9):1076-7. [Medline]. Bhattacharyya S, Davar J, Dreyfus G, Caplin ME. Carcinoid heart disease. Circulation. 2007 Dec 11. 116(24):2860-5. [Medline]. [emedicine.medscape.com]

Braunwald's Heart Disease: a Textbook of Cardiovascular Medicine. 7th ed. Philadelphia: Elsevier; 2005. p. 1587. [ Google Scholar ] [ncbi.nlm.nih.gov]

In 1955, Selzer and colleagues ( 6 ) ( Figure 1 ) described a 62-year-old man with severe hypertension (blood pressure 260/140 mm Hg) hospitalized because of nausea, hepatomegaly, distended neck veins, and clear lung fields. [ncbi.nlm.nih.gov]

Hokkaido Perinatal Epidemiology Study Group. 4G/5G variant of plasminogen activator inhibitor-1 gene and severe pregnancy-induced hypertension: subgroup analyses of variants of angiotensinogen and endothelial nitric oxide synthase. J. [en.aig-journal.ru]

[…] or simply preceded signs of left-sided heart failure (dyspnea). [ncbi.nlm.nih.gov]

During subsequent years he developed evidence of severe heart failure, runs of ventricular tachycardia, atrial fibrillation, and a murmur consistent with mitral regurgitation. An intracardiac defibrillator was inserted when he was 63 years old. [ncbi.nlm.nih.gov]

In 1955, Selzer and colleagues ( 6 ) ( Figure 1 ) described a 62-year-old man with severe hypertension (blood pressure 260/140 mm Hg) hospitalized because of nausea, hepatomegaly, distended neck veins, and clear lung fields. [ncbi.nlm.nih.gov]

Kidney failure Hypopituitarism Liver failure Diagnosis [ edit ] Radiologic osteosclerosis and histology are the main diagnostic features. [en.wikipedia.org]

Selzer et al argued rightfully that “‘encroachment’ of the cardiac septum on the cavity of the right ventricle appears to be a normal phenomenon, or may be an accentuation of normal conditions by left ventricular hypertrophy.” [ncbi.nlm.nih.gov]