Presentation
Suppurative complications of group A beta-hemolytic Streptococcus infection can present acutely and progress rapidly if prompt treatment is not initiated. Awareness of uncommon presentations is essential. [ncbi.nlm.nih.gov]
Fever was the main presenting feature in this case but it was the presentation of patient with multiple cerebral infarcts that lead to the diagnosis of infective endocarditis. [ecommons.aku.edu]
Entire Body System
- Sepsis
Despite the presence of sepsis, bilateral pulmonary congestion and bleeding were observed without pneumonia. Due to the rapid progression of sepsis, there was no time for granulocyte migration from the bone marrow. [ncbi.nlm.nih.gov]
Despite the marked male predominance, few reviews of neonatal sepsis mention how many infants were circumcised. [cirp.org]
- Surgical Procedure
Risk factors including being old, males (>2:1 vs females), diabetes, chronic cardiac disease, CKD, cirrhosis, alcoholism, immunocompromised state, and surgical procedures. [errolozdalga.com]
There have been reports of newborns 5-7 who have been circumcised and then developed life threatening infection within several days of this procedure. [cirp.org]
People with abnormal or damaged heart valves are given courses of antibiotics when they have some types of surgical procedures, including dental work, to help prevent endocarditis from developing from the shedding of bacteria into the bloodstream that [humanillnesses.com]
Surgical procedures such as suction lipectomy, hysterectomy, vaginal delivery, bunionectomy and bone pinning provide a portal of entry in some cases. [antimicrobe.org]
- Pallor
The rash is seen best on the abdomen or lateral chest and as dark red lines in skinfolds (Pastia lines) or as circumoral pallor. [merckmanuals.com]
The exanthem spares the mouth creating circumoral pallor. The rash is finely papular with a texture of coarse sandpaper. [ahcmedia.com]
S carlet Fever: Scarlet fever is characterized by high fever, circumoral pallor and a diffuse erythematous rash over the neck, trunk, face and limbs. There is a sandpaper consistency to the rash which blanches with pressure. [antimicrobe.org]
- Malaise
COMPLICATION : Acute Glomerulonephritis The major clinical and laboratory manifestations of acute post-streptococcal glomerulonephritis are: CLINICAL FEATURES LABORATORY FINDINGS Abrupt onset Hematuria, cylindruria Headache, malaise Proteinuria Edema, [atsu.edu]
The majority of scarlet fever patients do experience associated symptoms of malaise, fever, head- ache, and abdominal pain, with or without vomiting. On examination, patients are not ill. [ahcmedia.com]
Respiratoric
- Pneumonia
sepsis, meningitis in newborns S. pneumoniae: community - acquired pneumonia, meningitis, otitis media Viridans Group streptococci: endocarditis, bacteremia (particularly in setting of oral mucosal disruption) Laboratory Culture conditions: Blood agar [pathologyoutlines.com]
Streptococcus pneumoniae S. pneumoniae is usually found on the surface of the skin and inside the throat. It causes infections in both adults and children. It is transmitted through coughs and sneezes. [yourgenome.org]
Despite the presence of sepsis, bilateral pulmonary congestion and bleeding were observed without pneumonia. Due to the rapid progression of sepsis, there was no time for granulocyte migration from the bone marrow. [ncbi.nlm.nih.gov]
Alpha-Hemolytic Streptococcus Pneumococci S. pneumoniae, a leading cause of bacterial pneumonia, otitis media and meningitis. [wikidoc.org]
Gastrointestinal
- Overeating
Group A beta hemolytic streptococcus (GABHS) was recovered from 22 (54%) of 41 specimens compared with 6 (35%) of 17 over the previous 12 years. [ncbi.nlm.nih.gov]
Exotoxin A - a super antigen which causes over production of cytokines 8. Cysteine protease (Exotoxin B) Pyoderma strains of S. pyogenes can colonize or survive on normal skin surfaces for extended periods. [atsu.edu]
Cardiovascular
- Tachycardia
An elderly diabetic man presents to hospital with a fever, tachycardia and hypotension. He is septic and so blood cultures are taken and he is started on IV Piptazobactam as per the hospitals empirical guidelines for sepsis. [microbiologynutsandbolts.co.uk]
Treatment of potentially life-threatening complications of GAS infections includes not only eradication of the organism from normally sterile sites throughout the body but also management of secondary problems -- namely, hypotension, tachycardia, and [emedicinehealth.com]
Tachycardia is disproportionately seen in relation to the height of the fever. [ahcmedia.com]
Jaw & Teeth
- Exudative Pharyngitis
James et al. [ 1 ] have associated group C SBH with exudative pharyngitis. Baquero et al. [ 2 ] also identified these species on its research work. [omicsonline.org]
- Coated Tongue
A patient seen within several days of the onset of the illness will have a white-coated tongue with protruding prominent red papillae. Within several additional days segments of the white coating disappear (see Figure 1). [ahcmedia.com]
Skin
- Erythema
These can help in the diagnosis of rheumatic fever, post-streptococcal glomerulonephritis and erythema nodosum. [dermnetnz.org]
Urticaria or erythema multiform occasionally develops. Scarlet fever may accompany streptococcal pyoderma or wound infection (surgical scarlet fever). [atsu.edu]
Classic streptococcal tonsillopharyngitis has an acute onset; produces concurrent headache, stomach ache, and dysphagia; and upon examination is characterized by intense tonsillopharyngeal erythema, yellow exudate, and tender/enlarged anterior cervical [ncbi.nlm.nih.gov]
The interpretation of what constitutes an infected circumcision is problematic because the wound often has some exudate and erythema without other definite signs of infection. [cirp.org]
Other findings of ARF include erythema marginatum (usually over the spine or other bony areas) and a red expanding rash on the trunk and extremities that recurs over weeks to months. [en.wikipedia.org]
- Papule
The macules develop into papules as they elevate above the skin surface. The papules briefly fill with a clear liquid and lysis rapidly occurs. A serous discharge creates an oozing superficial lesion. [ahcmedia.com]
Workup
His workup showed evidence of infection and multiple cerebral infarcts on the right side. Blood culture grew Streptococcus pyogens. Echocardiogram showed two vegetations on the aortic valve. [ecommons.aku.edu]
Microbiology
- Gram-Positive Bacteria
These are streptococci (round or ovoid gram - positive bacteria) that are characterised by their ability to lyse red blood cells. [gpnotebook.co.uk]
Group A beta-hemolytic streptococci (GABHS) are gram-positive bacteria that grow in culture as pairs or chains of variable length. [pedsinreview.aappublications.org]
Michael Gibson, M.S., M.D. [1] Overview Streptococcus is a genus of spherical Gram-positive bacteria, belonging to the phylum Firmicutes [1] and the lactic acid bacteria group. [wikidoc.org]
A Gram stain is performed to show Gram-positive cocci in chains. [en.wikipedia.org]
Mupirocin is effective against gram-positive bacteria, especially methicillin-sensitive Staphylococcus aureus (MSSA) and GABHS. [ahcmedia.com]
- Gram-Positive Coccus
Group A Strep (GAS) Infection Related Articles Group A Strep (GAS) Infection Facts Streptococcus pyogenes, also known as group A beta-hemolytic Streptococcus, or group A strep ( GAS ) is a gram-positive coccus (spherical bacteria) that is ubiquitous, [emedicinehealth.com]
Wilde, MD, FAAP, Associate Professor, Emergency Medicine and Pediatrics, Section Chief, Pediatric Emergency Medicine, Medical College of Georgia, Augusta, GA Streptococcus pyogenes is an aerobic, gram-positive coccus, forming either short or long chains [ahcmedia.com]
G ENERAL DESCRIPTION M icrobiology Streptococcus pyogenes, or Group A streptococcus (GAS), is a facultative, Gram-positive coccus which grows in chains and causes numerous infections in humans including pharyngitis, tonsillitis, scarlet fever, cellulitis [antimicrobe.org]
- Beta-Hemolytic Streptococcus Group A
Also Known As Group B Beta-hemolytic Streptococcus Group B Streptococcus Group B Strep GBS Strep Group B Streptococcus agalactiae Beta-hemolytic Strep Culture Formal Name Prenatal Group B Streptococcus Screening This article was last modified on May 6 [labtestsonline.org]
Treatment
OBJECTIVE: To confirm that treatment with an extract of Pelargonium sidoides (EPs 7630) is superior to placebo for the treatment of non-GABHS tonsillopharyngitis in children. DESIGN: Randomized, double-blind, placebo-controlled trial. [ncbi.nlm.nih.gov]
Prognosis
What is the prognosis of a group B strep infection? The prognosis of a GBS infection varies depending on various factors, including the patient's age and the presence of any underlying medical conditions. [medicinenet.com]
Group A Strep (GAS) Infection Prognosis Tonsillopharyngitis and uncomplicated skin and soft-tissue infections caused by GAS have a good prognosis. [emedicinehealth.com]
Prognosis GAS is responsible for more than 2,000 deaths a year. About one in five people infected with flesh-eating bacteria die. So do three out of every five people who develop streptococcal toxic shock syndrome. [encyclopedia.com]
Long-term prognosis is generally thought to be excellent, but some studies found that up to 20% of patients develop urinary abnormalities ( 13 ). [antimicrobe.org]
Etiology
Keywords Adolescent — Adult — Female — Humans — Male — Meningitis, Bacterial/ etiology/microbiology — Middle Aged — Streptococcal Infections/ etiology/microbiology — Streptococcus pyogenes/pathogenicity — Virulence Identifiers DOI: 10.1086/520461 PMID [archive-ouverte.unige.ch]
We discuss the etiology and pathogenesis of this rare infection. [ncbi.nlm.nih.gov]
Incidence of specific etiology and role of methods for specific etiologic diagnosis of primary acute pericarditis. Am J Cardiol 1995; 75:378-382 Chapter 9 SPECIFIC PERICARDIAL DISORDERS Congenital malformations and acquired diseases 1. [books.google.es]
ETIOLOGICAL AGENT : Streptococcus pyogenes NOTE : All beta-hemolytic streptococci are grouped from A to U based on the C-antigen (Lancefield classification). [atsu.edu]
Epidemiology
Epidemiological analysis of group A streptococci recovered from patients in China. J Med Microbiol 2006;55:1101-7. [Table 1], [Table 2] [jlponline.org]
Modes of transmission, age distribution of cases, and other epidemiologic features are similar to those for streptococcal pharyngitis. [emedicine.medscape.com]
& Schuchat A. (2002) Epidemiology of Invasive Group A Streptococcus Disease in the United States, 1995-1999. Clinical Infectious Diseases. 35, 268-276. 4. Efstratiou A. (2000) Group A streptococci in the 1990s. [alere.com]
Evolving epidemiology of pediatric Staphylococcus aureus cutaneous infections in a Baltimore hospital. Pediatr Emerg Care 2006;22:717-723. 22. Kilbane BJ, Reynolds SL. [ahcmedia.com]
Sub-typing strains of GAS has proven invaluable for epidemiological studies, in much the same way that phage typing has been useful to define the epidemiology of Staphylococcus aureus. [antimicrobe.org]
Pathophysiology
The pathophysiology, classification, and treatment of invasive group A streptococcal infection is discussed. [ncbi.nlm.nih.gov]
Recent interest in the pathophysiology of this disorder has focused on the role of streptococcal pyrogenic exotoxins (SPEs), extracellular products of group A streptococci that mediate not only scarlatiniform-like rashes but also multi-organ damage and [antimicrobe.org]
Prevention
Benzathine penicillin chemoprophylaxis is safe and effective for interdicting and preventing GABHS outbreaks in closed, healthy young adult populations. [ncbi.nlm.nih.gov]
Group B Strep Prevention (GBS, baby strep, Group B streptococcal bacteria) General Public, Frequently Asked Questions. Centers for Disease Control and Prevention [On-line information]. [labtestsonline.it]
Centers for Disease Control and Prevention. Available online at https://www.cdc.gov/Features/GroupBStrep/. Accessed on 3/19/17. (2016 May 23 Updated). Group B Strep (GBS), Prevention in Newborns Centers for Disease Control and Prevention. [labtestsonline.org]