Presentation
Suppurative complications of group A beta-hemolytic Streptococcus infection can present acutely and progress rapidly if prompt treatment is not initiated. Awareness of uncommon presentations is essential. [ncbi.nlm.nih.gov]
Fever was the main presenting feature in this case but it was the presentation of patient with multiple cerebral infarcts that lead to the diagnosis of infective endocarditis. [ecommons.aku.edu]
Entire Body System
- Malaise
COMPLICATION : Acute Glomerulonephritis The major clinical and laboratory manifestations of acute post-streptococcal glomerulonephritis are: CLINICAL FEATURES LABORATORY FINDINGS Abrupt onset Hematuria, cylindruria Headache, malaise Proteinuria Edema, [atsu.edu]
The majority of scarlet fever patients do experience associated symptoms of malaise, fever, head- ache, and abdominal pain, with or without vomiting. On examination, patients are not ill. [ahcmedia.com]
- Constitutional Symptom
Constitutional symptoms include fever and chills, myalgias, headaches and nausea. Physical findings may include petechiae of the palate, pharyngeal and tonsillar erythema and exudates, and anterior cervical adenopathy. [aafp.org]
Cardiovascular
- Tachycardia
An elderly diabetic man presents to hospital with a fever, tachycardia and hypotension. He is septic and so blood cultures are taken and he is started on IV Piptazobactam as per the hospitals empirical guidelines for sepsis. [microbiologynutsandbolts.co.uk]
Treatment of potentially life-threatening complications of GAS infections includes not only eradication of the organism from normally sterile sites throughout the body but also management of secondary problems -- namely, hypotension, tachycardia, and [emedicinehealth.com]
Tachycardia is disproportionately seen in relation to the height of the fever. [ahcmedia.com]
Jaw & Teeth
- Exudative Pharyngitis
James et al. [ 1 ] have associated group C SBH with exudative pharyngitis. Baquero et al. [ 2 ] also identified these species on its research work. [omicsonline.org]
Skin
- Pruritus
Patients first present with perianal pruritus. More than half of the patients then exhibit rectal pain that is exacerbated with defecation. [ahcmedia.com]
Symptoms include a serous vaginal discharge, erythema of the vulvar area, and intense pruritus. Therapy consists of orally administered penicillin for 10 days. Patients allergic to penicillin can be treated with erythromycin. [antimicrobe.org]
Neurologic
- Tic Disorder
Therapeutic plasma exchange and intravenous immunoglobulin for obsessive compulsive disorder and tic disorders in childhood. (1999) Oct Lancet 2;354(9185):1153-8. 8. Orvidas LJ, Slattery MJ. [priory.com]
[…] and tic disorders. [emedicinehealth.com]
Reports of obsessive-compulsive disorder (OCD), tic disorders, and other neuropsychiatric symptoms occurring in association with group A beta-hemolytic streptococcal infections suggest that various CNS sequelae may be triggered by poststreptococcal autoimmunity [emedicine.medscape.com]
PANDAS [ edit ] A subset of children with acute, rapid-onset of tic disorders and obsessive compulsive disorder (OCD) are hypothesized to be due to an autoimmune response to group A beta-hemolytic streptococcal infection ( PANDAS ). [27] References [ [en.wikipedia.org]
PANDAS syndrome (pediatric autoimmune neuropsychiatric disorder associated with group A streptococci) refers to a subset of obsessive disorders or tic disorders in children thought to be exacerbated by GABHS infection. [merckmanuals.com]
Urogenital
- Vaginal Discharge
Symptoms include a serous vaginal discharge, erythema of the vulvar area, and intense pruritus. Therapy consists of orally administered penicillin for 10 days. Patients allergic to penicillin can be treated with erythromycin. [antimicrobe.org]
Workup
His workup showed evidence of infection and multiple cerebral infarcts on the right side. Blood culture grew Streptococcus pyogens. Echocardiogram showed two vegetations on the aortic valve. [ecommons.aku.edu]
Microbiology
- Gram-Positive Bacteria
These are streptococci (round or ovoid gram - positive bacteria) that are characterised by their ability to lyse red blood cells. [gpnotebook.co.uk]
Group A beta-hemolytic streptococci (GABHS) are gram-positive bacteria that grow in culture as pairs or chains of variable length. [pedsinreview.aappublications.org]
Michael Gibson, M.S., M.D. [1] Overview Streptococcus is a genus of spherical Gram-positive bacteria, belonging to the phylum Firmicutes [1] and the lactic acid bacteria group. [wikidoc.org]
A Gram stain is performed to show Gram-positive cocci in chains. [en.wikipedia.org]
Mupirocin is effective against gram-positive bacteria, especially methicillin-sensitive Staphylococcus aureus (MSSA) and GABHS. [ahcmedia.com]
- Gram-Positive Coccus
Group A Strep (GAS) Infection Related Articles Group A Strep (GAS) Infection Facts Streptococcus pyogenes, also known as group A beta-hemolytic Streptococcus, or group A strep ( GAS ) is a gram-positive coccus (spherical bacteria) that is ubiquitous, [emedicinehealth.com]
Wilde, MD, FAAP, Associate Professor, Emergency Medicine and Pediatrics, Section Chief, Pediatric Emergency Medicine, Medical College of Georgia, Augusta, GA Streptococcus pyogenes is an aerobic, gram-positive coccus, forming either short or long chains [ahcmedia.com]
G ENERAL DESCRIPTION M icrobiology Streptococcus pyogenes, or Group A streptococcus (GAS), is a facultative, Gram-positive coccus which grows in chains and causes numerous infections in humans including pharyngitis, tonsillitis, scarlet fever, cellulitis [antimicrobe.org]
- Beta-Hemolytic Streptococcus Group A
Also Known As Group B Beta-hemolytic Streptococcus Group B Streptococcus Group B Strep GBS Strep Group B Streptococcus agalactiae Beta-hemolytic Strep Culture Formal Name Prenatal Group B Streptococcus Screening This article was last modified on May 6 [labtestsonline.org]
- Candida
Nonbacterial causes are infrequent but include varicella zoster, herpes simplex and Candida species. 69 Bacteria are the primary cause of supraglottitis. Prior to the 1980s, Haemophilus influenzae accounted for all but 1% of the cases. [ahcmedia.com]
Treatment
OBJECTIVE: To confirm that treatment with an extract of Pelargonium sidoides (EPs 7630) is superior to placebo for the treatment of non-GABHS tonsillopharyngitis in children. DESIGN: Randomized, double-blind, placebo-controlled trial. [ncbi.nlm.nih.gov]
Prognosis
What is the prognosis of a group B strep infection? The prognosis of a GBS infection varies depending on various factors, including the patient's age and the presence of any underlying medical conditions. [medicinenet.com]
Group A Strep (GAS) Infection Prognosis Tonsillopharyngitis and uncomplicated skin and soft-tissue infections caused by GAS have a good prognosis. [emedicinehealth.com]
Prognosis GAS is responsible for more than 2,000 deaths a year. About one in five people infected with flesh-eating bacteria die. So do three out of every five people who develop streptococcal toxic shock syndrome. [encyclopedia.com]
Long-term prognosis is generally thought to be excellent, but some studies found that up to 20% of patients develop urinary abnormalities ( 13 ). [antimicrobe.org]
Etiology
Keywords Adolescent — Adult — Female — Humans — Male — Meningitis, Bacterial/ etiology/microbiology — Middle Aged — Streptococcal Infections/ etiology/microbiology — Streptococcus pyogenes/pathogenicity — Virulence Identifiers DOI: 10.1086/520461 PMID [archive-ouverte.unige.ch]
We discuss the etiology and pathogenesis of this rare infection. [ncbi.nlm.nih.gov]
Incidence of specific etiology and role of methods for specific etiologic diagnosis of primary acute pericarditis. Am J Cardiol 1995; 75:378-382 Chapter 9 SPECIFIC PERICARDIAL DISORDERS Congenital malformations and acquired diseases 1. [books.google.es]
ETIOLOGICAL AGENT : Streptococcus pyogenes NOTE : All beta-hemolytic streptococci are grouped from A to U based on the C-antigen (Lancefield classification). [atsu.edu]
Epidemiology
Epidemiological analysis of group A streptococci recovered from patients in China. J Med Microbiol 2006;55:1101-7. [Table 1], [Table 2] [jlponline.org]
Modes of transmission, age distribution of cases, and other epidemiologic features are similar to those for streptococcal pharyngitis. [emedicine.medscape.com]
& Schuchat A. (2002) Epidemiology of Invasive Group A Streptococcus Disease in the United States, 1995-1999. Clinical Infectious Diseases. 35, 268-276. 4. Efstratiou A. (2000) Group A streptococci in the 1990s. [alere.com]
Evolving epidemiology of pediatric Staphylococcus aureus cutaneous infections in a Baltimore hospital. Pediatr Emerg Care 2006;22:717-723. 22. Kilbane BJ, Reynolds SL. [ahcmedia.com]
Sub-typing strains of GAS has proven invaluable for epidemiological studies, in much the same way that phage typing has been useful to define the epidemiology of Staphylococcus aureus. [antimicrobe.org]
Pathophysiology
The pathophysiology, classification, and treatment of invasive group A streptococcal infection is discussed. [ncbi.nlm.nih.gov]
Recent interest in the pathophysiology of this disorder has focused on the role of streptococcal pyrogenic exotoxins (SPEs), extracellular products of group A streptococci that mediate not only scarlatiniform-like rashes but also multi-organ damage and [antimicrobe.org]
Prevention
Benzathine penicillin chemoprophylaxis is safe and effective for interdicting and preventing GABHS outbreaks in closed, healthy young adult populations. [ncbi.nlm.nih.gov]
Group B Strep Prevention (GBS, baby strep, Group B streptococcal bacteria) General Public, Frequently Asked Questions. Centers for Disease Control and Prevention [On-line information]. [labtestsonline.it]
Centers for Disease Control and Prevention. Available online at https://www.cdc.gov/Features/GroupBStrep/. Accessed on 3/19/17. (2016 May 23 Updated). Group B Strep (GBS), Prevention in Newborns Centers for Disease Control and Prevention. [labtestsonline.org]