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Beta-Hemolytic Streptococcus

Beta Hemolytic Streptococcus


Presentation

  • Abstract Suppurative complications of group A beta-hemolytic Streptococcus infection can present acutely and progress rapidly if prompt treatment is not initiated. Awareness of uncommon presentations is essential.[ncbi.nlm.nih.gov]
  • The clinical picture of toxic shock syndrome (TSS) presenting with purpura fulminans and limb ischemia is an exceptionally uncommon finding in sepsis due to GABHS.[ncbi.nlm.nih.gov]
  • A rare case of graft infection of thoracic aorta in terms of causative organism, long period from graft replacement to graft infection, and site of infection is presented and discussed.[ncbi.nlm.nih.gov]
  • Systemic GBS infection in an outpatient population can involve infants up to eight months old, is more common in blacks than in whites, can be present without fever or compromised appearance, and usually has low mortality.[ncbi.nlm.nih.gov]
  • Abstract Group A beta-hemolytic Streptococcus is a rare cause of peripartum infection, but it remains an extremely virulent pathogen with devastating consequences, thus requiring awareness of its presentation.[ncbi.nlm.nih.gov]
Malaise
  • COMPLICATION : Acute Glomerulonephritis The major clinical and laboratory manifestations of acute post-streptococcal glomerulonephritis are: CLINICAL FEATURES LABORATORY FINDINGS Abrupt onset Hematuria, cylindruria Headache, malaise Proteinuria Edema,[atsu.edu]
Regurgitation
  • One month after the initial echocardiogram, a repeat examination revealed worsening aortic regurgitation and mitral regurgitation.[ncbi.nlm.nih.gov]
Neonatal Jaundice
  • We report here a neonate with late onset GBS infection manifesting as a urinary tract infection (UTI) in an infant presenting with prolonged neonatal jaundice. The pathogenesis of this late onset is postulated.[ncbi.nlm.nih.gov]
Jaundice
  • We report here a neonate with late onset GBS infection manifesting as a urinary tract infection (UTI) in an infant presenting with prolonged neonatal jaundice. The pathogenesis of this late onset is postulated.[ncbi.nlm.nih.gov]
Exudative Pharyngitis
  • James et al. [ 1 ] have associated group C SBH with exudative pharyngitis. Baquero et al. [ 2 ] also identified these species on its research work.[omicsonline.org]
Tachycardia
  • An elderly diabetic man presents to hospital with a fever, tachycardia and hypotension. He is septic and so blood cultures are taken and he is started on IV Piptazobactam as per the hospitals empirical guidelines for sepsis.[microbiologynutsandbolts.co.uk]
Diastolic Murmur
  • After developing a harsh, diastolic murmur that led to an echocardiogram, aortic valve endocarditis was diagnosed. A 6-week course of intravenous penicillin G was administered.[ncbi.nlm.nih.gov]

Workup

  • His workup showed evidence of infection and multiple cerebral infarcts on the right side. Blood culture grew Streptococcus pyogens. Echocardiogram showed two vegetations on the aortic valve.[ecommons.aku.edu]
Gram-Positive Bacteria
  • These are streptococci (round or ovoid gram - positive bacteria) that are characterised by their ability to lyse red blood cells.[gpnotebook.co.uk]
  • Group A beta-hemolytic streptococci (GABHS) are gram-positive bacteria that grow in culture as pairs or chains of variable length.[pedsinreview.aappublications.org]
  • ., M.D. [1] Overview Streptococcus is a genus of spherical Gram-positive bacteria, belonging to the phylum Firmicutes [1] and the lactic acid bacteria group.[wikidoc.org]
  • However, S. dysgalactiae can also be group A. [1] S. pyogenes is a beta-hemolytic species of Gram positive bacteria that is responsible for a wide range of both invasive and noninvasive infections. [2] Infection of GAS may spread through direct contact[en.wikipedia.org]
Beta-Hemolytic Streptococcus Group A
  • Also Known As Group B Beta-hemolytic Streptococcus Group B Streptococcus Group B Strep GBS Strep Group B Streptococcus agalactiae Beta-hemolytic Strep Culture Formal Name Prenatal Group B Streptococcus Screening This article was last modified on May 6[labtestsonline.org]
Capnocytophaga Ochracea
  • We report the clinical and laboratory findings of a child in whom culture of the thyroid pus yielded two bacteria which are part of the normal oropharyngeal flora: capnocytophaga ochracea and group F Beta-hemolytic streptococcus.[ncbi.nlm.nih.gov]

Treatment

  • OBJECTIVE: To confirm that treatment with an extract of Pelargonium sidoides (EPs 7630) is superior to placebo for the treatment of non-GABHS tonsillopharyngitis in children. DESIGN: Randomized, double-blind, placebo-controlled trial.[ncbi.nlm.nih.gov]
  • Mothers colonized at this time may be considered candidates for prophylactic antibiotic treatment.[ncbi.nlm.nih.gov]
  • The rates of delayed treatment, unnecessary treatment, and increased costs were compared using different combinations of the clinical scoring system, the in-office streptococcal test, and culture.[ncbi.nlm.nih.gov]
  • Treatment included i.v. antibiotics: ampicillin/sulbactam or clindamycin plus either cefuroxime or ceftriaxone, followed by oral amoxicillin/clavulanate or clindamycin. All patients recovered.[ncbi.nlm.nih.gov]
  • These results may have treatment implications if use continues to be high.[ncbi.nlm.nih.gov]

Prognosis

  • What is the prognosis of a group B strep infection? The prognosis of a GBS infection varies depending on various factors, including the patient's age and the presence of any underlying medical conditions.[medicinenet.com]

Etiology

  • We discuss the etiology and pathogenesis of this rare infection.[ncbi.nlm.nih.gov]
  • Keywords Adolescent — Adult — Female — Humans — Male — Meningitis, Bacterial/ etiology/microbiology — Middle Aged — Streptococcal Infections/ etiology/microbiology — Streptococcus pyogenes/pathogenicity — Virulence Identifiers DOI: 10.1086/520461 PMID[archive-ouverte.unige.ch]
  • Incidence of specific etiology and role of methods for specific etiologic diagnosis of primary acute pericarditis. Am J Cardiol 1995; 75:378-382 Chapter 9 SPECIFIC PERICARDIAL DISORDERS Congenital malformations and acquired diseases 1. ‎[books.google.es]
  • ETIOLOGICAL AGENT : Streptococcus pyogenes NOTE : All beta-hemolytic streptococci are grouped from A to U based on the C-antigen (Lancefield classification).[atsu.edu]
  • Most children and adolescents who develop a sore throat do not have GABHS as the cause; their infection is viral in etiology.[ncbi.nlm.nih.gov]

Epidemiology

  • Epidemiological analysis of group A streptococci recovered from patients in China. J Med Microbiol 2006;55:1101-7. [Table 1], [Table 2][jlponline.org]
  • . & Schuchat A. (2002) Epidemiology of Invasive Group A Streptococcus Disease in the United States, 1995-1999. Clinical Infectious Diseases. 35, 268-276. 4. Efstratiou A. (2000) Group A streptococci in the 1990s.[alere.com]
  • These findings lend epidemiologic evidence that PANDAS may arise as a result of a post infectious autoimmune phenomenon induced by childhood streptococcal infection.[priory.com]
  • References Turner JC, Hayden FG, Lobo MC, Ramirez CE, Murren D (1997) Epidemiologic evidence for Lancefield group C beta-hemolytic streptococci as a cause of exudative pharyngitis in college students.J ClinMicrobiol 35: 1-4.[omicsonline.org]
  • "Group A Streptococcus Epidemiology and Vaccine Implications". Clinical Infectious Diseases. 45 (7): 863–5. doi : 10.1086/521263. PMID 17806050. Carapetis, JR; Steer, AC; Mulholland, EK; Weber, M (November 2005).[en.wikipedia.org]
Sex distribution
Age distribution

Pathophysiology

  • The pathophysiology, classification, and treatment of invasive group A streptococcal infection is discussed.[ncbi.nlm.nih.gov]
  • Anti-GM1 IgM was significantly elevated in his serum during the acute phase, which suggested that it was related with the pathophysiology in this patient.[ncbi.nlm.nih.gov]

Prevention

  • Benzathine penicillin chemoprophylaxis is safe and effective for interdicting and preventing GABHS outbreaks in closed, healthy young adult populations.[ncbi.nlm.nih.gov]
  • CONCLUSION: Women who are colonized with Group B streptococcus and who have cerebrospinal fluid shunts should receive perinatal antibiotic prophylaxis, and may require more extended prophylactic antibiotics with cesarean section deliveries to prevent[ncbi.nlm.nih.gov]
  • Forty-four women colonized with GB-BHS at 38 weeks' gestation were randomly assigned to a treatment (500 mg potassium penicillin or erythromycin ethylsuccinate q.i.d.) or a control group to determine the value of antepartum oral antibiotic therapy in preventing[ncbi.nlm.nih.gov]
  • A live, attenuated vaccine exists to prevent this illness, but controversy remains concerning the need to vaccinate children for what is generally a benign, self-limited disease, although more states are currently recommending this vaccine.[ncbi.nlm.nih.gov]

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